A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk.

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Published in Cancer Res on October 15, 2008

Authors

Lena J Chin1, Elena Ratner, Shuguang Leng, Rihong Zhai, Sunitha Nallur, Imran Babar, Roman-Ulrich Muller, Eva Straka, Li Su, Elizabeth A Burki, Richard E Crowell, Rajeshvari Patel, Trupti Kulkarni, Robert Homer, Daniel Zelterman, Kenneth K Kidd, Yong Zhu, David C Christiani, Steven A Belinsky, Frank J Slack, Joanne B Weidhaas

Author Affiliations

1: Department of Molecular, Yale University, New Haven, Connecticut 06520, USA.

Associated clinical trials:

Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment | NCT02253251

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