Effects of deoxycholylglycine, a conjugated secondary bile acid, on myogenic tone and agonist-induced contraction in rat resistance arteries.

PubWeight™: 0.84‹?›

🔗 View Article (PMC 3281111)

Published in PLoS One on February 16, 2012

Authors

Sandeep Khurana1, Hema Raina, Valeria Pappas, Jean-Pierre Raufman, Thomas L Pallone

Author Affiliations

1: Division of Gastroenterology and Hepatology, VA Maryland Health Care System and University of Maryland School of Medicine, Baltimore, Maryland, United States of America. skhurana@medicine.umaryland.edu

Articles cited by this

A G protein-coupled receptor responsive to bile acids. J Biol Chem (2003) 4.76

The cardiac output at rest in Laennec's cirrhosis. J Clin Invest (1953) 3.94

Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates. Hepatology (2004) 3.66

Bile acids as regulatory molecules. J Lipid Res (2009) 3.23

Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter. Circ Res (2004) 2.60

Structural basis of TEA blockade in a model potassium channel. Nat Struct Mol Biol (2005) 1.77

Invited review: arteriolar smooth muscle mechanotransduction: Ca(2+) signaling pathways underlying myogenic reactivity. J Appl Physiol (1985) (2001) 1.74

Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction. EMBO J (2008) 1.71

The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells. Hepatology (2007) 1.69

Portal hypertension and its complications. Gastroenterology (2008) 1.50

Serum bile acids in liver disease. Gut (1971) 1.50

Expression and activation of the farnesoid X receptor in the vasculature. Proc Natl Acad Sci U S A (2004) 1.48

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders. Trends Pharmacol Sci (2009) 1.45

Vitamin D receptor activators can protect against vascular calcification. J Am Soc Nephrol (2008) 1.35

Beta1 (KCNMB1) subunits mediate lithocholate activation of large-conductance Ca2+-activated K+ channels and dilation in small, resistance-size arteries. Mol Pharmacol (2007) 1.34

The emerging role of Ca2+ sensitivity regulation in promoting myogenic vasoconstriction. Cardiovasc Res (2008) 1.30

Neural mechanisms of angiotensin II-salt hypertension: implications for therapies targeting neural control of the splanchnic circulation. Curr Hypertens Rep (2011) 1.29

Mesenteric arcade arteries contribute substantially to vascular resistance in conscious rats. J Vasc Res (1993) 1.22

Natural bile acids and synthetic analogues modulate large conductance Ca2+-activated K+ (BKCa) channel activity in smooth muscle cells. J Gen Physiol (2002) 1.20

Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. Diabetes Care (2009) 1.19

Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes. PLoS One (2010) 1.15

Rapid intracellular TEA block of the KcsA potassium channel. Biophys J (2004) 1.15

Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells. Circ Res (2005) 1.12

Mesenteric blood pressure profile of conscious, freely moving rats. J Physiol (1995) 1.11

Attenuation of conducted vasodilatation in rat mesenteric arteries during hypertension: role of inwardly rectifying potassium channels. J Physiol (2004) 1.07

FXR-mediated regulation of eNOS expression in vascular endothelial cells. Cardiovasc Res (2007) 1.06

Selective interaction of bile acids with muscarinic receptors: a case of molecular mimicry. Eur J Pharmacol (2002) 1.02

Role of portal and splenic vein shunts and impaired hepatic extraction in the elevated serum bile acids in liver cirrhosis. Gastroenterology (1984) 1.01

Regional heterogeneity in acetylcholine-induced relaxation in rat vascular bed: role of calcium-activated K+ channels. Am J Physiol Heart Circ Physiol (2006) 0.98

Lithocholyltaurine interacts with cholinergic receptors on dispersed chief cells from guinea pig stomach. Am J Physiol (1998) 0.97

Bile acids regulate cardiovascular function. Clin Transl Sci (2011) 0.95

Vasoactive effects of bile salts in cirrhotic rats: in vivo and in vitro studies. Hepatology (1993) 0.94

Regulation of vascular tone during pregnancy: a novel role for the pregnane X receptor. Hypertension (2006) 0.92

Functional expression of NOS 1 in vascular smooth muscle. Am J Physiol Heart Circ Physiol (2000) 0.91

FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells. Cardiovasc Res (2007) 0.90

Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. Eur J Pharmacol (2005) 0.89

Deoxycholic acid conjugates are muscarinic cholinergic receptor antagonists. Pharmacology (2002) 0.87

Voltage-gated divalent currents in descending vasa recta pericytes. Am J Physiol Renal Physiol (2010) 0.86

Sympathetic nerves and the endothelium influence the vasoconstrictor effect of low concentrations of ouabain in pressurized small arteries. Am J Physiol Heart Circ Physiol (2010) 0.86

Baroreflex sensitivity is impaired in patients with obstructive jaundice. Anesthesiology (2009) 0.85

Presence and vascular pharmacology of KATP channel subtypes in rat central and peripheral tissues. Eur J Pharmacol (2010) 0.85

Calcium dynamics and vasomotion in arteries subject to isometric, isobaric, and isotonic conditions. Biophys J (2008) 0.84

Sequential changes in serum levels of individual bile acids in patients with chronic cholestatic liver disease. J Gastroenterol Hepatol (1996) 0.83

Bile acids increase intracellular Ca(2+) concentration and nitric oxide production in vascular endothelial cells. Br J Pharmacol (2000) 0.80

Serum bile acids in patients with liver failure supported with a bioartificial liver. Aliment Pharmacol Ther (2002) 0.80

Mechanism of bile salt vasoactivity: dependence on calcium channels in vascular smooth muscle. Br J Pharmacol (1994) 0.79

Postprandial plasma concentrations of glycine and taurine conjugated bile acids in healthy subjects. Gut (1983) 0.76

Articles by these authors

Quality assessment of colonoscopic cecal intubation: an analysis of 6 years of continuous practice at a university hospital. Am J Gastroenterol (2006) 3.49

Vasa recta pericytes express a strong inward rectifier K+ conductance. Am J Physiol Regul Integr Comp Physiol (2006) 1.49

Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors. Biochem Pharmacol (2005) 1.44

How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension. Am J Physiol Heart Circ Physiol (2011) 1.43

Muscarinic receptors and ligands in cancer. Am J Physiol Cell Physiol (2008) 1.42

Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse. Am J Physiol Cell Physiol (2003) 1.35

Human cecal bile acids: concentration and spectrum. Am J Physiol Gastrointest Liver Physiol (2007) 1.35

The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension (2008) 1.32

Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. Biochem Pharmacol (2006) 1.30

Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells. Cancer Res (2003) 1.28

Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter. Mol Pharm (2009) 1.26

Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells. Am J Physiol Gastrointest Liver Physiol (2009) 1.19

Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation. Am J Physiol Gastrointest Liver Physiol (2008) 1.19

3',5'-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation. Biochem Biophys Res Commun (2005) 1.07

Functional interaction of lithocholic acid conjugates with M3 muscarinic receptors on a human colon cancer cell line. Biochim Biophys Acta (2002) 1.07

Low-dose ouabain constricts small arteries from ouabain-hypertensive rats: implications for sustained elevation of vascular resistance. Am J Physiol Heart Circ Physiol (2009) 1.04

Ouabain modulation of cellular calcium stores and signaling. Am J Physiol Renal Physiol (2007) 1.01

Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. Am J Physiol Gastrointest Liver Physiol (2011) 1.01

Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis. Exp Cell Res (2008) 1.00

In vivo assessment of artery smooth muscle [Ca2+]i and MLCK activation in FRET-based biosensor mice. Am J Physiol Heart Circ Physiol (2010) 0.99

A technique for simultaneous measurement of Ca2+, FRET fluorescence and force in intact mouse small arteries. J Physiol (2008) 0.98

Membrane potential controls calcium entry into descending vasa recta pericytes. Am J Physiol Regul Integr Comp Physiol (2002) 0.97

Intrinsic nitric oxide and superoxide production regulates descending vasa recta contraction. Am J Physiol Renal Physiol (2010) 0.96

Sympathetic neurogenic Ca2+ signalling in rat arteries: ATP, noradrenaline and neuropeptide Y. Exp Physiol (2008) 0.96

Vasodilatory effects of cholinergic agonists are greatly diminished in aorta from M3R-/- mice. Eur J Pharmacol (2004) 0.96

Bile acids regulate cardiovascular function. Clin Transl Sci (2011) 0.95

Iodixanol, constriction of medullary descending vasa recta, and risk for contrast medium-induced nephropathy. Radiology (2009) 0.95

Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation. Am J Physiol Gastrointest Liver Physiol (2012) 0.94

Response of descending vasa recta to luminal pressure. Am J Physiol Renal Physiol (2004) 0.93

Descending vasa recta endothelium is an electrical syncytium. Am J Physiol Regul Integr Comp Physiol (2006) 0.93

Increased arterial smooth muscle Ca2+ signaling, vasoconstriction, and myogenic reactivity in Milan hypertensive rats. Am J Physiol Heart Circ Physiol (2011) 0.92

Membrane current oscillations in descending vasa recta pericytes. Am J Physiol Renal Physiol (2008) 0.92

Cholinergic agonist-induced pepsinogen secretion from murine gastric chief cells is mediated by M1 and M3 muscarinic receptors. Am J Physiol Gastrointest Liver Physiol (2005) 0.91

Ca(2+) signaling and membrane potential in descending vasa recta pericytes and endothelia. Am J Physiol Renal Physiol (2002) 0.90

ANG II signaling in vasa recta pericytes by PKC and reactive oxygen species. Am J Physiol Heart Circ Physiol (2004) 0.90

Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. Eur J Pharmacol (2005) 0.89

Chronic ANG II infusion increases NO generation by rat descending vasa recta. Am J Physiol Heart Circ Physiol (2004) 0.89

In vivo performance of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile acid transport. Mol Pharm (2014) 0.89

A survey of credentialing practices of gastrointestinal endoscopy centers in the United States. J Clin Gastroenterol (2005) 0.88

Hepatitis C knowledge among primary care residents: is our teaching adequate for the times? Am J Gastroenterol (2004) 0.88

Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis. BMC Cancer (2013) 0.87

Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta. Am J Physiol Cell Physiol (2004) 0.87

Heterozygosity for factor V Leiden and G20210A prothrombin genotypes in a patient with mesenteric vein thrombosis. Dig Dis Sci (2002) 0.86

Sympathetic nerves and the endothelium influence the vasoconstrictor effect of low concentrations of ouabain in pressurized small arteries. Am J Physiol Heart Circ Physiol (2010) 0.86

Voltage-gated divalent currents in descending vasa recta pericytes. Am J Physiol Renal Physiol (2010) 0.86

Lithocholylcholine, a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist. J Pharmacol Exp Ther (2002) 0.86

Muscarinic receptor signaling in colon cancer. Cancers (Basel) (2011) 0.86

Descending vasa recta pericytes express voltage operated Na+ conductance in the rat. J Physiol (2005) 0.86

Chronic ouabain treatment induces vasa recta endothelial dysfunction in the rat. Am J Physiol Renal Physiol (2008) 0.85

KATP channel conductance of descending vasa recta pericytes. Am J Physiol Renal Physiol (2005) 0.85

SlimQuick™ - associated hepatotoxicity in a woman with alpha-1 antitrypsin heterozygosity. World J Hepatol (2012) 0.85

Design and characterization of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile Acid transporter activity. Pharm Res (2013) 0.84

Hsp70A and GlsA interact as partner chaperones to regulate asymmetric division in Volvox. Dev Biol (2005) 0.84

Modification of cytosolic calcium signaling by subplasmalemmal microdomains. Am J Physiol Renal Physiol (2007) 0.84

Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury. J Pharmacol Exp Ther (2010) 0.84

Vasa recta voltage-gated Na+ channel Nav1.3 is regulated by calmodulin. Am J Physiol Renal Physiol (2006) 0.83

Mechanisms underlying angiotensin II-induced calcium oscillations. Am J Physiol Renal Physiol (2008) 0.83

High vascular tone of mouse femoral arteries in vivo is determined by sympathetic nerve activity via α1A- and α1D-adrenoceptor subtypes. PLoS One (2013) 0.83

Cellular mechanisms underlying nitric oxide-induced vasodilation of descending vasa recta. Am J Physiol Renal Physiol (2010) 0.83

Angiotensin II constriction of rat vasa recta is partially thromboxane dependent. Hypertension (2002) 0.82

RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer. Inflamm Bowel Dis (2013) 0.82

Notch transcriptional control of vascular smooth muscle regulatory gene expression and function. J Biol Chem (2013) 0.82

Mural propagation of descending vasa recta responses to mechanical stimulation. Am J Physiol Renal Physiol (2013) 0.81

ANG II AT2 receptor modulates AT1 receptor-mediated descending vasa recta endothelial Ca2+ signaling. Am J Physiol Heart Circ Physiol (2002) 0.81

Descending vasa recta endothelia express inward rectifier potassium channels. Am J Physiol Renal Physiol (2007) 0.81

Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging. J Pharm Sci (2014) 0.81

Ouabain modulation of endothelial calcium signaling in descending vasa recta. Am J Physiol Renal Physiol (2006) 0.80

Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice. Biochem Pharmacol (2013) 0.79

Gastrointestinal peptides and regulation of gastric acid secretion. Curr Opin Endocrinol Diabetes Obes (2010) 0.79

Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis. PLoS One (2012) 0.79

Murine vasa recta pericyte chloride conductance is controlled by calcium, depolarization, and kinase activity. Am J Physiol Regul Integr Comp Physiol (2010) 0.79

The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of β1PIX with β-catenin. J Biol Chem (2013) 0.78

Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids. Carcinogenesis (2015) 0.78

Descending vasa recta endothelial cells and pericytes form mural syncytia. Am J Physiol Renal Physiol (2013) 0.78

Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium. Inflamm Bowel Dis (2015) 0.77

Sodium pumps: ouabain, ion transport, and signaling in hypertension. Am J Physiol Renal Physiol (2007) 0.76

Anatomic classification of the endoscopic appearance of the normal appendiceal orifice: a novel tool for recognition and documentation of cecal intubation. Clin Anat (2011) 0.75

Control of renal Na+ excretion by heme oxygenase. Hypertension (2006) 0.75

Microvascular effects of aldosterone and angiotensin type 2 receptors. Hypertension (2005) 0.75

Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma. Mayo Clin Proc (2013) 0.75

Declining gastrointestinal opportunistic infections in HIV-infected persons: a triumph of science and a challenge for our HAARTs and minds. Am J Gastroenterol (2005) 0.75

Aquaporin 1, urea transporters, and renal vascular bundles. J Am Soc Nephrol (2007) 0.75

Seroprevalence of H. pylori infection and symptoms of upper gastrointestinal tract disease in two groups of health-care workers. Dig Dis Sci (2002) 0.75