Y Eugene Chin

Author PubWeight™ 48.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 2005 5.31
2 Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis. Nat Med 2013 2.85
3 A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy. Kidney Int 2010 2.32
4 Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Mol Cell Biol 2009 1.80
5 Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. J Exp Med 2008 1.76
6 Acetylation-dependent signal transduction for type I interferon receptor. Cell 2007 1.68
7 Au-Fe3O4 dumbbell nanoparticles as dual-functional probes. Angew Chem Int Ed Engl 2008 1.64
8 P2X7 receptors mediate deleterious renal epithelial-fibroblast cross talk. Am J Physiol Renal Physiol 2010 1.57
9 Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol 2009 1.53
10 Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation. Genes Dev 2003 1.51
11 Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. J Immunol 2009 1.45
12 SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nuclei. J Biol Chem 2002 1.44
13 Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation. J Biol Chem 2002 1.28
14 FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways. Obesity (Silver Spring) 2010 1.24
15 Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells. Mol Cell Biol 2004 1.19
16 Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity. J Biol Chem 2010 1.16
17 SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol Cell 2012 1.11
18 Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts. J Biol Chem 2012 1.08
19 Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II. Mol Cell Biol 2005 1.06
20 Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. J Biol Chem 2006 1.05
21 The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy. Cell Metab 2013 1.01
22 Acetylation modulates prolactin receptor dimerization. Proc Natl Acad Sci U S A 2010 1.01
23 Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer. J Biol Chem 2012 0.96
24 Monodisperse magnetite nanoparticles coupled with nuclear localization signal peptide for cell-nucleus targeting. Chem Asian J 2008 0.93
25 DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis. J Clin Invest 2014 0.89
26 Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways. Am J Physiol Renal Physiol 2009 0.87
27 STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells. Am J Physiol Gastrointest Liver Physiol 2007 0.87
28 Novel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phase influencing cell migration and second phase directing cell proliferation. J Biol Chem 2012 0.86
29 Transglutaminase-1 regulates renal epithelial cell proliferation through activation of Stat-3. J Biol Chem 2008 0.85
30 Identification of the linker-SH2 domain of STAT as the origin of the SH2 domain using two-dimensional structural alignment. Mol Cell Proteomics 2004 0.85
31 Antibodies immobilized as arrays to profile protein post-translational modifications in mammalian cells. Mol Cell Proteomics 2004 0.84
32 Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine. J Biol Chem 2012 0.83
33 CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation. Cell Death Differ 2012 0.82
34 Phospho-SXXE/D motif mediated TNF receptor 1-TRADD death domain complex formation for T cell activation and migration. J Immunol 2011 0.81
35 Gprc5a-deficiency confers susceptibility to endotoxin-induced acute lung injury via NF-κB pathway. Cell Cycle 2015 0.80
36 EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer. Mol Cancer 2014 0.78
37 Antibody array platform to monitor protein tyrosine phosphorylation in mammalian cells. Methods Mol Biol 2009 0.77
38 PRBC-derived plasma induces non-muscle myosin type IIA-mediated neutrophil migration and morphologic change. Immunopharmacol Immunotoxicol 2012 0.75
39 mTOR and post-translational modifications rely on mitochondrion as the arsenal for cellular metabolism regulation. Sci China Life Sci 2015 0.75