Published in PLoS One on March 05, 2012
Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations. Reprod Toxicol (2013) 1.23
Long non-coding RNA regulation of reproduction and development. Mol Reprod Dev (2015) 0.82
Paramutation and related phenomena in diverse species. Nat Rev Genet (2016) 0.76
Could interallelic interactions be a key to the epigenetic aspects of fitness-trait inbreeding depression? Heredity (Edinb) (2013) 0.75
Imprinted DNA methylation reconstituted at a non-imprinted locus. Epigenetics Chromatin (2016) 0.75
Simplified mammalian DNA isolation procedure. Nucleic Acids Res (1991) 12.56
Epigenetic reprogramming in mouse primordial germ cells. Mech Dev (2002) 6.67
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev (1998) 6.29
Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature (1997) 5.08
Inheritance of a cancer-associated MLH1 germ-line epimutation. N Engl J Med (2007) 4.87
Germline epimutation of MLH1 in individuals with multiple cancers. Nat Genet (2004) 4.74
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
Characterization of the chicken beta-globin insulator. Proc Natl Acad Sci U S A (1997) 3.57
Transgenerational epigenetic effects. Annu Rev Genomics Hum Genet (2008) 3.16
CTCF maintains differential methylation at the Igf2/H19 locus. Nat Genet (2002) 3.15
Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science (2004) 2.98
Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev (2009) 2.76
The pre-implantation ontogeny of the H19 methylation imprint. Nat Genet (1997) 2.28
Gene-specific timing and epigenetic memory in oocyte imprinting. Hum Mol Genet (2004) 2.25
Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance. Mol Cell Biol (2004) 2.24
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus. PLoS Genet (2008) 2.08
Regulation of DNA methylation of Rasgrf1. Nat Genet (2001) 2.06
Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation. Nature (1987) 2.00
Timing of establishment of paternal methylation imprints in the mouse. Genomics (2004) 1.84
H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19. Genes Dev (2000) 1.70
Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Mol Cell Biol (2005) 1.43
Imprinting of Igf2 and H19 from a 130 kb YAC transgene. Development (1997) 1.43
Epigenetic inheritance in the mouse. Curr Biol (1997) 1.40
The imprinting box of the Prader-Willi/Angelman syndrome domain. Nat Genet (2000) 1.37
The imprinting box of the mouse Igf2r gene. Nature (1999) 1.36
Trans allele methylation and paramutation-like effects in mice. Nat Genet (2003) 1.15
The H19 differentially methylated region marks the parental origin of a heterologous locus without gametic DNA methylation. Mol Cell Biol (2004) 1.14
Control elements within the PWS/AS imprinting box and their function in the imprinting process. Hum Mol Genet (2004) 1.11
Methylation imprints of the imprint control region of the SNRPN-gene in human gametes and preimplantation embryos. Hum Mol Genet (2003) 1.01
Elucidation of the minimal sequence required to imprint H19 transgenes. Genomics (2001) 1.00
Timing and sequence requirements defined for embryonic maintenance of imprinted DNA methylation at Rasgrf1. Mol Cell Biol (2006) 0.99
Imprint control element-mediated secondary methylation imprints at the Igf2/H19 locus. J Biol Chem (2002) 0.98
A human H19 transgene exhibits impaired paternal-specific imprint acquisition and maintenance in mice. Hum Mol Genet (2002) 0.86
Distal transgene insertion affects CpG island maintenance during differentiation. J Biol Chem (2008) 0.85
Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature (2002) 9.51
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature (2005) 7.72
Lysosomal glycosphingolipid recognition by NKT cells. Science (2004) 7.31
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell (2012) 6.71
CD-HIT Suite: a web server for clustering and comparing biological sequences. Bioinformatics (2010) 6.68
Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development. Plant Cell (2007) 4.13
Transcriptome-wide identification of novel imprinted genes in neonatal mouse brain. PLoS One (2008) 4.03
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet (2002) 3.88
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. Cancer Cell (2013) 2.50
Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth. Neuron (2002) 2.48
Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Plant Physiol (2005) 2.23
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus. PLoS Genet (2008) 2.08
Regulation of DNA methylation of Rasgrf1. Nat Genet (2001) 2.06
Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells. J Am Chem Soc (2004) 2.05
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system. Mol Pharmacol (2010) 1.81
Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes. Plant Physiol (2004) 1.79
Real-time analysis and selection of methylated DNA by fluorescence-activated single molecule sorting in a nanofluidic channel. Proc Natl Acad Sci U S A (2012) 1.70
Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells. Biochem Biophys Res Commun (2007) 1.69
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. PLoS Biol (2009) 1.61
Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis. Genome Biol (2005) 1.55
Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer. Nat Rev Genet (2013) 1.53
Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats. Ann Thorac Surg (2011) 1.52
Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. Am J Pathol (2004) 1.52
Single molecule epigenetic analysis in a nanofluidic channel. Anal Chem (2010) 1.52
Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis. Plant Cell (2002) 1.52
The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. J Neurosci (2006) 1.51
Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Mol Cell Biol (2005) 1.43
Changes of the proportion and mortality of pulmonary thromboembolism in hospitalized patients from 1974 to 2005. Chin Med J (Engl) (2006) 1.40
Individual Timp deficiencies differentially impact pro-MMP-2 activation. J Biol Chem (2006) 1.34
Androgenic regulation of oxidative stress in the rat prostate: involvement of NAD(P)H oxidases and antioxidant defense machinery during prostatic involution and regrowth. Am J Pathol (2003) 1.33
DNA methylation, imprinting and cancer. Eur J Hum Genet (2002) 1.32
Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha. J Leukoc Biol (2007) 1.32
TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation. Circ Res (2010) 1.32
Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology (2005) 1.31
Targeting autophagy augments in vitro and in vivo antimyeloma activity of DNA-damaging chemotherapy. Clin Cancer Res (2011) 1.30
A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development. Plant Physiol (2003) 1.27
Coordinate regulation of DNA methylation and H3K27me3 in mouse embryonic stem cells. PLoS One (2013) 1.24
Potential of mean force for protein-protein interaction studies. Proteins (2002) 1.24
Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers. Bioconjug Chem (2008) 1.24
A survey for novel imprinted genes in the mouse placenta by mRNA-seq. Genetics (2011) 1.24
The RSC chromatin remodelling ATPase translocates DNA with high force and small step size. EMBO J (2011) 1.24
Alterations in cardiac DNA methylation in human dilated cardiomyopathy. EMBO Mol Med (2013) 1.23
Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates myogenesis and beta1 integrin expression in vitro. Exp Cell Res (2007) 1.23
Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells. Proc Natl Acad Sci U S A (2013) 1.21
The role of glycogen synthase kinase 3beta in the transformation of epidermal cells. Cancer Res (2007) 1.19
Increased medial degradation with pseudo-aneurysm formation in apolipoprotein E-knockout mice deficient in tissue inhibitor of metalloproteinases-1. Circulation (2003) 1.18
Late abscess formation following indirect hernia repair utilizing silk suture. Pediatr Surg Int (2007) 1.18
Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice. Am J Respir Cell Mol Biol (2005) 1.17
Trans allele methylation and paramutation-like effects in mice. Nat Genet (2003) 1.15
20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol (2008) 1.15
Primary protein response after ligand photodissociation in carbonmonoxy myoglobin. Proc Natl Acad Sci U S A (2007) 1.14
Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice. Am J Pathol (2006) 1.14
Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation. J Biol Chem (2003) 1.13
Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation (2009) 1.12
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition. J Biol Chem (2006) 1.11
Tissue inhibitor of metalloproteinases-1 (TIMP-1) modulates neuronal death, axonal plasticity, and learning and memory. Eur J Neurosci (2005) 1.10
Clinical and pathological features of renal involvement in propylthiouracil-associated ANCA-positive vasculitis. Am J Kidney Dis (2007) 1.09
Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. Life Sci (2008) 1.09
Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population. Carcinogenesis (2013) 1.08
Star-shape copolymer of lysine-linked di-tocopherol polyethylene glycol 2000 succinate for doxorubicin delivery with reversal of multidrug resistance. Biomaterials (2012) 1.06
Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin-Beck disease. Arthritis Rheum (2010) 1.06
Prevalence and risk factors for diabetic retinopathy: the Beijing Communities Diabetes Study 6. Retina (2012) 1.06
20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells. Am J Physiol Heart Circ Physiol (2009) 1.05
Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131. Antimicrob Agents Chemother (2007) 1.05
Eco-physiological characteristics of alfalfa seedlings in response to various mixed salt-alkaline stresses. J Integr Plant Biol (2008) 1.05
Dysregulation of unfolded protein response partially underlies proapoptotic activity of bortezomib in multiple myeloma cells. Leuk Lymphoma (2009) 1.05
DOCKGROUND protein-protein docking decoy set. Bioinformatics (2008) 1.03
Paternally biased X inactivation in mouse neonatal brain. Genome Biol (2010) 1.03
Propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis. Nat Rev Nephrol (2012) 1.03
Tissue inhibitor of metalloproteinase 1 regulates resistance to infection. Infect Immun (2005) 1.03
TNF-alpha gene promoter -238G>A and -308G>A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis. J Invest Dermatol (2007) 1.01
Imprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1. Mamm Genome (2009) 1.00
Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors. Bioorg Med Chem (2008) 1.00
Receptors for myelin inhibitors: Structures and therapeutic opportunities. Mol Cell Neurosci (2009) 1.00
Endostar induces apoptotic effects in HUVECs through activation of caspase-3 and decrease of Bcl-2. Anticancer Res (2009) 1.00
Successful computational prediction of novel imprinted genes from epigenomic features. Mol Cell Biol (2010) 1.00
Reduced expression of the androgen receptor by third generation of antisense shows antitumor activity in models of prostate cancer. Mol Cancer Ther (2011) 1.00
Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates neuromuscular junction development via a beta1 integrin-mediated mechanism. J Neurobiol (2006) 0.99
Timing and sequence requirements defined for embryonic maintenance of imprinted DNA methylation at Rasgrf1. Mol Cell Biol (2006) 0.99
Histopathological changes of Ceroplastes japonicus infected by Lecanicillium lecanii. J Invertebr Pathol (2009) 0.98
Placebo acupuncture devices: considerations for acupuncture research. Evid Based Complement Alternat Med (2013) 0.98
The size of the intermolecular energy funnel in protein-protein interactions. Proteins (2008) 0.98
Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. J Biol Chem (2008) 0.98
Single-molecule observation of helix staggering, sliding, and coiled coil misfolding. Proc Natl Acad Sci U S A (2012) 0.98
Comparison of the cerebrospinal fluid (CSF) toluidine red unheated serum test and the CSF rapid plasma reagin test with the CSF venereal disease research laboratory test for diagnosis of neurosyphilis among HIV-negative syphilis patients in China. J Clin Microbiol (2013) 0.97
Plants can benefit from herbivory: stimulatory effects of sheep saliva on growth of Leymus chinensis. PLoS One (2012) 0.96
20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt. Am J Physiol Lung Cell Mol Physiol (2010) 0.96
Angiogenesis and osteogenesis enhanced by bFGF ex vivo gene therapy for bone tissue engineering in reconstruction of calvarial defects. J Biomed Mater Res A (2011) 0.96
A classification of Hashimoto's thyroiditis based on immunohistochemistry for IgG4 and IgG. Thyroid (2013) 0.96
Biologic contribution of P1 promoter-mediated expression of ST6Gal I sialyltransferase. Glycobiology (2003) 0.96
Role of TGF-beta family in osteoclastogenesis induced by RANKL. Cell Signal (2002) 0.96
Microfluidic extraction, stretching and analysis of human chromosomal DNA from single cells. Lab Chip (2012) 0.95