Published in Nature on November 03, 1987
Genomic imprinting: review and relevance to human diseases. Am J Hum Genet (1990) 4.73
Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission. Proc Natl Acad Sci U S A (2003) 4.70
Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nat Rev Genet (2012) 2.93
A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting. Proc Natl Acad Sci U S A (1989) 2.02
Two dominant mutations in the mouse fused gene are the result of transposon insertions. Genetics (1997) 1.76
Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome. J Virol (1988) 1.68
Transgenerational epigenetic inheritance: more questions than answers. Genome Res (2010) 1.67
The structural H19 gene is required for transgene imprinting. Proc Natl Acad Sci U S A (1996) 1.55
The case for transgenerational epigenetic inheritance in humans. Mamm Genome (2008) 1.54
Population genetic models of genomic imprinting. Genetics (1992) 1.52
The marks, mechanisms and memory of epigenetic states in mammals. Biochem J (2001) 1.43
Uniparental heterodisomy for chromosome 14 in a phenotypically abnormal familial balanced 13/14 Robertsonian translocation carrier. Am J Hum Genet (1991) 1.43
Expression of a foreign gene in a line of transgenic mice is modulated by a chromosomal position effect. Mol Cell Biol (1990) 1.41
Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J Clin Invest (1994) 1.41
A 5' differentially methylated sequence and the 3'-flanking region are necessary for H19 transgene imprinting. Mol Cell Biol (1997) 1.40
Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am J Hum Genet (1993) 1.36
Genomic imprinting: a possible mechanism for the parental origin effect in Huntington's chorea. J Med Genet (1988) 1.33
Mouse U2af1-rs1 is a neomorphic imprinted gene. Mol Cell Biol (1997) 1.27
Bridging the transgenerational gap with epigenetic memory. Trends Genet (2013) 1.17
Imprinting capacity of gamete lineages in Caenorhabditis elegans. Genetics (2005) 1.15
Epigenetic inheritance of disease and disease risk. Neuropsychopharmacology (2012) 1.07
Complex patterns of inheritance of an imprinted murine transgene suggest incomplete germline erasure. Nucleic Acids Res (2000) 1.07
DNA methylation: a phoenix rises. Proc Natl Acad Sci U S A (1993) 1.02
Genomic imprinting: mechanism and role in human pathology. Am J Pathol (1994) 0.97
Mechanism and therapeutic potential of DNA-based immunization against the envelope proteins of hepatitis B virus in normal and transgenic mice. Immunology (2001) 0.95
Transcription of the S gene in transgenic mice is associated with hypomethylation at specific sites and with DNase I sensitivity. J Virol (1990) 0.91
Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively. J Virol (1988) 0.90
Testis-specific expression of a metallothionein I-driven transgene correlates with undermethylation of the locus in testicular DNA. Proc Natl Acad Sci U S A (1993) 0.90
The cloning of 3'-truncated preS/S gene from HBV genomic DNA and its expression in transgenic mice. World J Gastroenterol (2000) 0.90
Epigenetic genome-wide association methylation in aging and longevity. Epigenomics (2012) 0.88
The use of epigenetic phenomena for the improvement of sheep and cattle. Front Genet (2014) 0.85
Sequences sufficient for programming imprinted germline DNA methylation defined. PLoS One (2012) 0.82
No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations. Mamm Genome (2013) 0.82
Variable germline and embryonic instability of the human minisatellite MS32 (D1S8) in transgenic mice. EMBO J (1994) 0.81
Persistence or loss of preimposed methylation patterns and de novo methylation of foreign DNA integrated in transgenic mice. Nucleic Acids Res (1991) 0.79
A dominant modifier of transgene methylation is mapped by QTL analysis to mouse chromosome 13. Genome Res (2001) 0.79
Methylation status of genes flanking the fragile site in males with the fragile-X syndrome: a test of the imprinting hypothesis. Am J Hum Genet (1990) 0.77
Inducible mouse models illuminate parameters influencing epigenetic inheritance. Development (2013) 0.76
Epigenetic inheritance: a contributor to species differentiation? DNA Cell Biol (2012) 0.76
A role for epigenetic inheritance in modern evolutionary theory? A comment in response to Dickins and Rahman. Proc Biol Sci (2013) 0.75
Leaving the past behind. PLoS Genet (2008) 0.75
De novo methylation causes a tissue-specific polymorphic EcoRI pattern at the human epidermal growth factor receptor gene. Biochem J (1993) 0.75
Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting. Am J Hum Genet (1990) 0.75
Mouse chromosome 13. Mamm Genome (1992) 0.75
Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli. Nature (1979) 15.42
A physical map of 30,000 human genes. Science (1998) 12.43
The hepatitis B virus. Nature (1985) 8.71
Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses. Nature (1987) 7.96
Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus. Cell (1985) 7.86
Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Cell (1986) 6.12
Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene. Nature (1990) 5.50
Identification of a second human retinoic acid receptor. Nature (1988) 5.11
Biology of hepatitis B virus. Science (1981) 4.93
Cloning in Escherichia coli and physical structure of hepatitis B virion DNA. Proc Natl Acad Sci U S A (1979) 4.71
Bacteriophage lambda having EcoRI endonuclease sites only in the nonessential region of the genome. Proc Natl Acad Sci U S A (1974) 4.35
Large-scale identification of virulence genes from Streptococcus pneumoniae. Infect Immun (1998) 4.19
Excretion of hepatitis B surface antigen particles from mouse cells transformed with cloned viral DNA. Proc Natl Acad Sci U S A (1980) 3.97
Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab Invest (1984) 3.86
Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone. J Bacteriol (1996) 3.72
Transcription of the hepatitis B surface antigen gene in mouse cells transformed with cloned viral DNA. J Virol (1982) 3.51
Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious. Nature (1983) 3.43
Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proc Natl Acad Sci U S A (1998) 3.17
Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma. Nature (1980) 3.16
Detection of hepatitis B virus DNA in serum by a simple spot hybridization technique: comparison with results for other viral markers. Hepatology (1983) 3.11
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat Genet (2001) 3.10
Biosynthesis of hepatitis B virus surface antigen in Escherichia coli. Nature (1980) 3.00
Molecular comparison of virulence plasmids in Shigella and enteroinvasive Escherichia coli. Ann Microbiol (Paris) (1983) 2.93
Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies. Proc Natl Acad Sci U S A (1980) 2.88
Detection of hepatitis B virus DNA in liver and serum: a direct appraisal of the chronic carrier state. Lancet (1981) 2.80
High-efficiency transformation of Streptococcus lactis protoplasts by plasmid DNA. Appl Environ Microbiol (1986) 2.68
Nucleotide sequence and expression of the diphtheria tox228 gene in Escherichia coli. Science (1983) 2.65
Epidemiology of tension-type headache. JAMA (1998) 2.63
Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours. Nature (1990) 2.61
Pax: a murine multigene family of paired box-containing genes. Genomics (1991) 2.60
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet (2001) 2.60
Transcription of woodchuck hepatitis virus in the chronically infected liver. EMBO J (1985) 2.49
The cytoplasmic domain of simian immunodeficiency virus transmembrane protein modulates infectivity. J Virol (1989) 2.46
Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development (1990) 2.42
Localization on the viral genome and nucleotide sequence of the gene coding for the two major polypeptides of the hepatitis B surface antigen (HBs Ag). Nucleic Acids Res (1979) 2.42
Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes. EMBO J (1989) 2.41
Structure of two adenovirus type 12 transforming polypeptides and their evolutionary implications. Nature (1980) 2.38
State of hepatitis B virus DNA in hepatocytes of patients with hepatitis B surface antigen-positive and -negative liver diseases. Proc Natl Acad Sci U S A (1981) 2.37
Chagas' disease. Clin Microbiol Rev (1992) 2.30
Timing fracture repair in patients with severe brain injury (Glasgow Coma Scale score <9) J Trauma (1998) 2.24
Molecular cloning of lymphadenopathy-associated virus. Nature (1985) 2.22
Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma. Nature (1986) 2.21
Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development (1995) 2.20
In vitro and in vivo synthesis of the hepatitis B virus surface antigen and of the receptor for polymerized human serum albumin from recombinant human adenoviruses. EMBO J (1985) 2.18
Enhanced immunogenicity of the pre-S region of hepatitis B surface antigen. Science (1985) 2.18
Synthesis in animal cells of hepatitis B surface antigen particles carrying a receptor for polymerized human serum albumin. Proc Natl Acad Sci U S A (1984) 2.00
Medical consultation for migraine: results from the American Migraine Study. Headache (1998) 1.99
A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma. Nature (1988) 1.96
Transmission of hepatitis B from hepatitis-B-seronegative subjects. Lancet (1988) 1.95
Guidelines for treatment of atopic eczema (atopic dermatitis) part I. J Eur Acad Dermatol Venereol (2012) 1.77
Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer (1997) 1.74
A genomic approach of the hepatitis C virus generates a protein interaction map. Gene (2000) 1.72
Specific hepatitis B virus integration in hepatocellular carcinoma DNA through a viral 11-base-pair direct repeat. Proc Natl Acad Sci U S A (1984) 1.71
Specific expression of hepatitis B surface antigen (HBsAg) in transgenic mice. Science (1985) 1.70
Characterization of integrated hepatitis B viral DNA cloned from a human hepatoma and the hepatoma-derived cell line PLC/PRF/5. Proc Natl Acad Sci U S A (1983) 1.69
A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. Genes Dev (1988) 1.68
Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome. J Virol (1988) 1.68
Sodium di-N-propylacetate (DPA) in the treatment of epilepsy. A review. Epilepsia (1975) 1.63
[Cloning of the hepatitis B virus genome in Escherichia coli]. C R Acad Sci Hebd Seances Acad Sci D (1978) 1.62
DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans. Proc Natl Acad Sci U S A (1995) 1.60
Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma. Cell (1988) 1.58
EAACI/GA2LEN/EDF guideline: definition, classification and diagnosis of urticaria. Allergy (2006) 1.55
Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene (1997) 1.52
Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene. Proc Natl Acad Sci U S A (1985) 1.51
Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. Neurology (1999) 1.51
Leg ulcer care: an audit of cost-effectiveness. Health Trends (1996) 1.51
Guidelines for treatment of atopic eczema (atopic dermatitis) Part II. J Eur Acad Dermatol Venereol (2012) 1.49
Detection of hepatitis B virus DNA in mononuclear blood cells. Br Med J (Clin Res Ed) (1984) 1.49
Associations of blood lead, dimercaptosuccinic acid-chelatable lead, and tibia lead with neurobehavioral test scores in South Korean lead workers. Am J Epidemiol (2001) 1.46
Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy (2012) 1.46
Key priorities in managing glucose control in older people with diabetes. J Nutr Health Aging (2009) 1.45
DNA-methylase from regenerating rat liver: purification and characterisation. Nucleic Acids Res (1978) 1.44
Nucleotide sequence and evolution of ETn elements. Proc Natl Acad Sci U S A (1987) 1.42
The prevalence of positive reactions in the atopy patch test with aeroallergens and food allergens in subjects with atopic eczema: a European multicenter study. Allergy (2004) 1.42
Identification of variable-number tandem-repeat loci in Leptospira interrogans sensu stricto. J Clin Microbiol (2005) 1.41
ACE inhibitors do not induce recombinant human erythropoietin resistance in hemodialysis patients. Am J Kidney Dis (2000) 1.41
Synthesis of human interferon beta 1 in Escherichia coli infected by a lambda phage recombinant containing a human genomic fragment. Eur J Biochem (1981) 1.41
Complete DNA methylation does not prevent polyoma and simian virus 40 virus early gene expression. Proc Natl Acad Sci U S A (1983) 1.39
Diagnosis of Encephalitozoon cuniculi infection by western blot and the use of cross-reactive antigens for the possible detection of microsporidiosis in humans. Am J Trop Med Hyg (1992) 1.38
Widespread occurrence of spliceosomal introns in the rDNA genes of ascomycetes. Mol Biol Evol (2000) 1.37
Evidence that hepatitis B virus has a role in liver-cell carcinoma in alcoholic liver disease. N Engl J Med (1982) 1.37
Pulmonary aspiration during emergency endoscopy in patients with upper gastrointestinal hemorrhage. Crit Care Med (1991) 1.37
The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice. Nature (1986) 1.36
Associations of blood lead, dimercaptosuccinic acid-chelatable lead, and tibia lead with polymorphisms in the vitamin D receptor and [delta]-aminolevulinic acid dehydratase genes. Environ Health Perspect (2000) 1.35
Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors. J Virol (1992) 1.34
Fused transcripts of c-myc and a new cellular locus, hcr in a primary liver tumor. Oncogene (1989) 1.33
Associations of blood pressure and hypertension with lead dose measures and polymorphisms in the vitamin D receptor and delta-aminolevulinic acid dehydratase genes. Environ Health Perspect (2001) 1.33
Work-related disability: results from the American migraine study. Cephalalgia (1996) 1.32
Detection of hepatitis B virus DNA in pancreas, kidney and skin of two human carriers of the virus. J Gen Virol (1984) 1.32
Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1. Int J Cancer (1999) 1.31