Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation.

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Published in Immunity on March 08, 2012

Authors

Liang Shan1, Kai Deng, Neeta S Shroff, Christine M Durand, S Alireza Rabi, Hung-Chih Yang, Hao Zhang, Joseph B Margolick, Joel N Blankson, Robert F Siliciano

Author Affiliations

1: Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Associated clinical trials:

Research In Viral Eradication of HIV Reservoirs (RIVER) | NCT02336074

A Phase I/II Study to Evaluate the Immunologic Response and Virologic Impact of AGS-004 | NCT02042248

Enhancement by Poly-ICLC During HIV-1 Infection (Poly-ICLC) | NCT02071095

Phase I Study of HIV 1 Antigen Expanded Specific T Cell Therapy (HXTC) | NCT02208167

Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 Infection (VORVAX) | NCT02707900

Early Infant HIV Treatment in Botswana (EIT) | NCT02369406

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