Published in J Biol Chem on March 21, 2012
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Impaired contractile responses and altered expression and phosphorylation of Ca(2+) sensitization proteins in gastric antrum smooth muscles from ob/ob mice. J Muscle Res Cell Motil (2013) 0.89
Myosin phosphatase isoforms as determinants of smooth muscle contractile function and calcium sensitivity of force production. Microcirculation (2014) 0.85
Neural programming of mesenteric and renal arteries. Am J Physiol Heart Circ Physiol (2014) 0.82
A bioinformatic and computational study of myosin phosphatase subunit diversity. Am J Physiol Regul Integr Comp Physiol (2014) 0.81
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Transformer 2β homolog (Drosophila) (TRA2B) regulates protein kinase C δI (PKCδI) splice variant expression during 3T3L1 preadipocyte cell cycle. J Biol Chem (2014) 0.79
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High-efficiency somatic mutagenesis in smooth muscle cells and cardiac myocytes in SM22alpha-Cre transgenic mice. Genesis (2005) 1.99
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Unzipping the role of myosin light chain phosphatase in smooth muscle cell relaxation. J Biol Chem (2003) 1.19
Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing. Hum Mol Genet (2010) 1.19
Vascular smooth muscle phenotypic diversity and function. Physiol Genomics (2010) 1.18
Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development. PLoS Genet (2011) 1.17
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A myosin phosphatase targeting subunit isoform transition defines a smooth muscle developmental phenotypic switch. Am J Physiol Cell Physiol (2000) 1.11
Regulation of force in vascular smooth muscle. J Mol Cell Cardiol (2003) 1.08
Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy. Am J Physiol Cell Physiol (2007) 1.08
Myosin phosphatase isoform switching in vascular smooth muscle development. J Mol Cell Cardiol (2005) 1.07
Conditioning effect of blood flow on resistance artery smooth muscle myosin phosphatase. Circ Res (2007) 1.07
Determinants of the contractile properties in the embryonic chicken gizzard and aorta. Am J Physiol Cell Physiol (2000) 1.06
Dynamic changes in expression of myosin phosphatase in a model of portal hypertension. Am J Physiol Heart Circ Physiol (2004) 1.04
Vascular reactivity in heart failure: role of myosin light chain phosphatase. Circ Res (2004) 1.02
Tropomyosin exons as models for alternative splicing. Adv Exp Med Biol (2008) 0.99
Tra2beta as a novel mediator of vascular smooth muscle diversification. Circ Res (2008) 0.96
Analysis of U1 small nuclear RNA interaction with cyclin H. J Biol Chem (2005) 0.94
The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing. Nucleic Acids Res (2006) 0.92
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MYPT1 protein isoforms are differentially phosphorylated by protein kinase G. J Biol Chem (2011) 0.91
Molecular design of a splicing switch responsive to the RNA binding protein Tra2β. Nucleic Acids Res (2011) 0.90
Regulation of basal LC20 phosphorylation by MYPT1 and CPI-17 in murine gastric antrum, gastric fundus, and proximal colon smooth muscles. Neurogastroenterol Motil (2011) 0.89
CaM kinase II in colonic smooth muscle contributes to dysmotility in murine DSS-colitis. Neurogastroenterol Motil (2009) 0.87
Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle. Am J Physiol Gastrointest Liver Physiol (2009) 0.86
Expression of Tra2beta isoforms is developmentally regulated in a tissue- and temporal-specific pattern. Cell Biol Int (2003) 0.85
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Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy. Am J Hum Genet (2001) 4.50
Exome sequencing identifies truncating mutations in human SERPINF1 in autosomal-recessive osteogenesis imperfecta. Am J Hum Genet (2011) 2.69
Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy. Science (2008) 2.51
Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2. Genet Med (2002) 2.26
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol Dis (2006) 1.96
hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1. Hum Mol Genet (2002) 1.84
SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy. Hum Mol Genet (2010) 1.80
PLS3 mutations in X-linked osteoporosis with fractures. N Engl J Med (2013) 1.66
Regulation of calcium-activated chloride channels in smooth muscle cells: a complex picture is emerging. Can J Physiol Pharmacol (2005) 1.62
A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus. Am J Hum Genet (2012) 1.57
Evidence for a modifying pathway in SMA discordant families: reduced SMN level decreases the amount of its interacting partners and Htra2-beta1. Hum Genet (2003) 1.52
In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate. Ann Neurol (2006) 1.48
In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy. J Neurochem (2006) 1.48
Histone deacetylase inhibitors: possible implications for neurodegenerative disorders. Expert Opin Investig Drugs (2008) 1.36
Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders. Am J Hum Genet (2008) 1.34
Mutations in BICD2, which encodes a golgin and important motor adaptor, cause congenital autosomal-dominant spinal muscular atrophy. Am J Hum Genet (2013) 1.32
Ca2+ sensitization pathways accessed by cholinergic neurotransmission in the murine gastric fundus. J Physiol (2013) 1.32
Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Hum Mol Genet (2011) 1.32
The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells. Hum Genet (2006) 1.27
Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition. Hum Mol Genet (2008) 1.26
An approximately 140-kb deletion associated with feline spinal muscular atrophy implies an essential LIX1 function for motor neuron survival. Genome Res (2006) 1.25
The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs. Microsc Microanal (2002) 1.23
LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate. Hum Mol Genet (2009) 1.21
Unzipping the role of myosin light chain phosphatase in smooth muscle cell relaxation. J Biol Chem (2003) 1.19
Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing. Hum Mol Genet (2010) 1.19
Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development. PLoS Genet (2011) 1.17
Extended phenotype of pontocerebellar hypoplasia with infantile spinal muscular atrophy. Am J Med Genet A (2003) 1.17
Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality. Hum Mol Genet (2012) 1.17
Regulation of Kv4.3 currents by Ca2+/calmodulin-dependent protein kinase II. Am J Physiol Cell Physiol (2004) 1.11
Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy. Am J Physiol Cell Physiol (2007) 1.08
Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. J Clin Invest (2014) 1.08
Myosin phosphatase isoform switching in vascular smooth muscle development. J Mol Cell Cardiol (2005) 1.07
Conditioning effect of blood flow on resistance artery smooth muscle myosin phosphatase. Circ Res (2007) 1.07
Dynamic changes in expression of myosin phosphatase in a model of portal hypertension. Am J Physiol Heart Circ Physiol (2004) 1.04
The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin. Hum Mol Genet (2011) 1.04
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy. Hum Mol Genet (2010) 1.03
Neuromuscular defects and breathing disorders in a new mouse model of spinal muscular atrophy. Neurobiol Dis (2010) 1.02
Calcineurin Aalpha but not Abeta augments ICl(Ca) in rabbit pulmonary artery smooth muscle cells. J Biol Chem (2004) 0.99
Tra2beta as a novel mediator of vascular smooth muscle diversification. Circ Res (2008) 0.96
Severe SMA mice show organ impairment that cannot be rescued by therapy with the HDACi JNJ-26481585. Eur J Hum Genet (2012) 0.96
Splicing of a myosin phosphatase targeting subunit 1 alternative exon is regulated by intronic cis-elements and a novel bipartite exonic enhancer/silencer element. J Biol Chem (2002) 0.96
Differential levels of tissue hypoxia in the developing chicken heart. Dev Dyn (2006) 0.96
Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract. Dev Biol (2004) 0.95
TIA proteins are necessary but not sufficient for the tissue-specific splicing of the myosin phosphatase targeting subunit 1. J Biol Chem (2004) 0.95
The development of the embryonic outflow tract provides novel insights into cardiac differentiation and remodeling. Trends Cardiovasc Med (2004) 0.95
Phospholamban knockout increases CaM kinase II activity and intracellular Ca2+ wave activity and alters contractile responses of murine gastric antrum. Am J Physiol Cell Physiol (2007) 0.94
Hypoxia-responsive signaling regulates the apoptosis-dependent remodeling of the embryonic avian cardiac outflow tract. Dev Biol (2004) 0.94
Dominant spinal muscular atrophy due to BICD2: a novel mutation refines the phenotype. J Neurol Neurosurg Psychiatry (2013) 0.92
Roles of CaM kinase II and phospholamban in SNP-induced relaxation of murine gastric fundus smooth muscles. Am J Physiol Cell Physiol (2006) 0.89
Sculpting the cardiac outflow tract. Birth Defects Res C Embryo Today (2003) 0.89
Splicing factor TRA2B is required for neural progenitor survival. J Comp Neurol (2014) 0.89
Impaired contractile responses and altered expression and phosphorylation of Ca(2+) sensitization proteins in gastric antrum smooth muscles from ob/ob mice. J Muscle Res Cell Motil (2013) 0.89
VPA response in SMA is suppressed by the fatty acid translocase CD36. Hum Mol Genet (2012) 0.87
Nuclear translocation of calcineurin Abeta but not calcineurin Aalpha by platelet-derived growth factor in rat aortic smooth muscle. Am J Physiol Cell Physiol (2007) 0.87
Altered hypoxia-inducible factor-1 alpha expression levels correlate with coronary vessel anomalies. Dev Dyn (2009) 0.87
Mutations of the LMNA gene can mimic autosomal dominant proximal spinal muscular atrophy. Neurogenetics (2006) 0.86
Differential autophosphorylation of CaM kinase II from phasic and tonic smooth muscle tissues. Am J Physiol Cell Physiol (2002) 0.86
Nonsense-mediated messenger RNA decay of survival motor neuron 1 causes spinal muscular atrophy. Hum Genet (2008) 0.86
Myosin phosphatase isoforms as determinants of smooth muscle contractile function and calcium sensitivity of force production. Microcirculation (2014) 0.85
Hypoxia-inducible transcription factor-1alpha triggers an autocrine survival pathway during embryonic cardiac outflow tract remodeling. Circ Res (2008) 0.85
Inhibition of BK channel activity by association with calcineurin in rat brain. Eur J Neurosci (2006) 0.85
X-linked infantile spinal muscular atrophy: clinical definition and molecular mapping. Genet Med (2007) 0.84
CaM kinase II activation and phospholamban phosphorylation by SNP in murine gastric antrum smooth muscles. Am J Physiol Gastrointest Liver Physiol (2006) 0.84
CaM kinase II and phospholamban contribute to caffeine-induced relaxation of murine gastric fundus smooth muscle. Am J Physiol Cell Physiol (2005) 0.84
Complex phosphatase regulation of Ca2+-activated Cl- currents in pulmonary arterial smooth muscle cells. J Biol Chem (2009) 0.84
High vascular tone of mouse femoral arteries in vivo is determined by sympathetic nerve activity via α1A- and α1D-adrenoceptor subtypes. PLoS One (2013) 0.83
Fas ligand gene transfer to the embryonic heart induces programmed cell death and outflow tract defects. Dev Biol (2004) 0.83
Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target. Neuropathol Appl Neurobiol (2014) 0.82
Neural programming of mesenteric and renal arteries. Am J Physiol Heart Circ Physiol (2014) 0.82
Notch transcriptional control of vascular smooth muscle regulatory gene expression and function. J Biol Chem (2013) 0.82
Smooth muscle contractile diversity in the control of regional circulations. Am J Physiol Heart Circ Physiol (2013) 0.81
Initiation of apoptosis in the developing avian outflow tract myocardium. Dev Dyn (2002) 0.81
Increasing SMN levels using the histone deacetylase inhibitor SAHA ameliorates defects in skeletal muscle microvasculature in a mouse model of severe spinal muscular atrophy. Neurosci Lett (2013) 0.80
Histone acetylation as a potential therapeutic target in motor neuron degenerative diseases. Curr Pharm Des (2013) 0.79
Role of VEGF and tissue hypoxia in patterning of neural and vascular cells recruited to the embryonic heart. Dev Dyn (2009) 0.79
Cyclosporin-A inhibits ERK phosphorylation in B cells by modulating the binding of Raf protein to Bcl2. Biochem Biophys Res Commun (2006) 0.79
Imaging the embryonic heart: how low can we go? How fast can we get? J Mol Cell Cardiol (2003) 0.79
Induction of PDE5 and de-sensitization to endogenous NO signaling in a systemic resistance artery under altered blood flow. J Mol Cell Cardiol (2009) 0.79
Investigational therapies for the treatment of spinal muscular atrophy. Expert Opin Investig Drugs (2015) 0.79
Dynamic patterns of apoptosis in the developing chicken heart. Dev Dyn (2004) 0.79
Stk31 is dispensable for embryonic development and spermatogenesis in mice. Mol Reprod Dev (2013) 0.78
Modulation of murine gastric antrum smooth muscle STOC activity and excitability by phospholamban. J Physiol (2008) 0.78
Biallelic Loss of Proprioception-Related PIEZO2 Causes Muscular Atrophy with Perinatal Respiratory Distress, Arthrogryposis, and Scoliosis. Am J Hum Genet (2016) 0.78
The zinc finger protein ZNF297B interacts with BDP1, a subunit of TFIIIB. Biol Chem (2006) 0.77
No evidence for DUP25 in patients with panic disorder using a quantitative real-time PCR approach. Hum Genet (2003) 0.76
Reply from Kenton M. Sanders, Bhupal P. Bhetwal and Brian A. Perrino. J Physiol (2013) 0.75
Cardiac myocyte cytokinesis: The contractile ring is the thing. J Mol Cell Cardiol (2006) 0.75
A paucisymptomatic neuromuscular disease mimicking type III 5q-SMA with complex rearrangements in the SMN gene. J Child Neurol (2013) 0.75