Published in Pancreas on August 01, 2012
Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation. Proc Natl Acad Sci U S A (2013) 0.88
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Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning. PLoS One (2013) 0.80
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Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res (2003) 103.76
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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development (2002) 12.21
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A (2000) 8.34
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet (2002) 8.28
Manual curation is not sufficient for annotation of genomic databases. Bioinformatics (2007) 4.16
A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell (2007) 4.13
Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res (2009) 3.44
An ultrastructural analysis of the developing embryonic pancreas. Dev Biol (1972) 3.00
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev (2005) 2.94
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Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
Cystathionine beta-synthase mutations in homocystinuria. Hum Mutat (1999) 1.96
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev Cell (2010) 1.90
Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS. Proc Natl Acad Sci U S A (2006) 1.77
Pathways and regulation of homocysteine metabolism in mammals. Semin Thromb Hemost (2000) 1.75
Rat endocrine pancreatic development in relation to two homeobox gene products (Pdx-1 and Nkx 6.1). J Histochem Cytochem (1998) 1.71
The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest (2009) 1.54
Biomedical discovery acceleration, with applications to craniofacial development. PLoS Comput Biol (2009) 1.49
Cell Lineage metastability in Gfi1-deficient mouse intestinal epithelium. Dev Biol (2010) 1.41
L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter. Diabetes (2006) 1.36
Gfi1 and Gfi1b: key regulators of hematopoiesis. Leukemia (2010) 1.32
Exploring biological networks with Cytoscape software. Curr Protoc Bioinformatics (2008) 1.30
Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development. Diabetes (2011) 1.30
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From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment. Curr Opin Immunol (2010) 1.25
Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Mol Endocrinol (2004) 1.23
A missense mutation in ALDH18A1, encoding Delta1-pyrroline-5-carboxylate synthase (P5CS), causes an autosomal recessive neurocutaneous syndrome. Eur J Hum Genet (2008) 1.20
Leveraging existing biological knowledge in the identification of candidate genes for facial dysmorphology. BMC Bioinformatics (2009) 1.13
Hormonal regulation of cystathionine beta-synthase expression in liver. J Biol Chem (2002) 1.10
Structural insights into mutations of cystathionine beta-synthase. Biochim Biophys Acta (2003) 1.10
Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse. Diabetes (2008) 1.09
The developmental regulation of amylolytic and proteolytic enzymes in the embryonic rat pancreas. J Biol Chem (1974) 1.09
Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. BMC Dev Biol (2009) 1.09
Pancreatic ductal morphogenesis and the Pdx1 homeodomain transcription factor. Mol Biol Cell (2009) 1.09
GeneSpeed: protein domain organization of the transcriptome. Nucleic Acids Res (2006) 1.07
EPConDB: a web resource for gene expression related to pancreatic development, beta-cell function and diabetes. Nucleic Acids Res (2006) 1.02
Production of pancreatic beta-cells from stem cells. Curr Diabetes Rev (2010) 1.02
Homocysteine metabolism in diabetes. Biochem Soc Trans (2007) 1.02
Gfi1-cells and circuits: unraveling transcriptional networks of development and disease. Curr Opin Hematol (2010) 1.01
Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose. FEBS Lett (2008) 1.00
Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10. Mech Dev (2009) 0.97
Association of variants within APOE, SORL1, RUNX1, BACE1 and ALDH18A1 with dementia in Alzheimer's disease in subjects with Down syndrome. Neurosci Lett (2010) 0.92
From endoderm to pancreas: a multistep journey. Cell Mol Life Sci (2007) 0.91
The pancreatic and duodenal homeobox protein PDX-1 regulates the ductal specific keratin 19 through the degradation of MEIS1 and DNA binding. PLoS One (2010) 0.87
Biochemistry and molecular genetics of cystathionine beta-synthase deficiency. Eur J Pediatr (1998) 0.87
GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist. Exp Diabetes Res (2008) 0.81
In vitro models of pancreatic differentiation using embryonic stem or induced pluripotent stem cells. Congenit Anom (Kyoto) (2011) 0.80
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A (2007) 6.44
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature (2005) 5.39
Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol (2004) 3.45
The structural and content aspects of abstracts versus bodies of full text journal articles are different. BMC Bioinformatics (2010) 2.88
AMIA Board white paper: definition of biomedical informatics and specification of core competencies for graduate education in the discipline. J Am Med Inform Assoc (2012) 2.40
Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides. Nat Biotechnol (2010) 2.38
Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells. Science (2007) 2.36
A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes. Diabetes (2008) 2.09
Gene copy number variation spanning 60 million years of human and primate evolution. Genome Res (2007) 2.02
Concept annotation in the CRAFT corpus. BMC Bioinformatics (2012) 1.94
Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young. Diabetes Care (2011) 1.86
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. J Clin Invest (2003) 1.73
Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes (2010) 1.67
Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. Biochem J (2009) 1.64
Proteomics as a tool for discovery: proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets. J Proteome Res (2003) 1.60
Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. Endocrinology (2005) 1.56
Diminished beta-cell replication contributes to reduced beta-cell mass in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol (2005) 1.54
Large-scale biomedical concept recognition: an evaluation of current automatic annotators and their parameters. BMC Bioinformatics (2014) 1.52
Biomedical discovery acceleration, with applications to craniofacial development. PLoS Comput Biol (2009) 1.49
A corpus of full-text journal articles is a robust evaluation tool for revealing differences in performance of biomedical natural language processing tools. BMC Bioinformatics (2012) 1.46
Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care (2012) 1.45
SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes. Ann N Y Acad Sci (2008) 1.42
Dense core vesicle dynamics in Caenorhabditis elegans neurons and the role of kinesin UNC-104. Traffic (2004) 1.36
Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8. J Immunol (2011) 1.28
The PhenoGen informatics website: tools for analyses of complex traits. BMC Genet (2007) 1.25
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone (2011) 1.21
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed. PLoS One (2009) 1.19
Diabetes antibody standardization program: first proficiency evaluation of assays for autoantibodies to zinc transporter 8. Clin Chem (2011) 1.17
Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. BMC Cancer (2010) 1.13
Novel diabetes autoantibodies and prediction of type 1 diabetes. Curr Diab Rep (2013) 1.13
Contribution of antibodies against IA-2β and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age. Diabetes Care (2011) 1.12
The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background. PLoS One (2012) 1.11
Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. PLoS One (2009) 1.11
Expression and regulation of chemokines in murine and human type 1 diabetes. Diabetes (2011) 1.10
Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse. Diabetes (2008) 1.09
A comparison of alternative 60-mer probe designs in an in-situ synthesized oligonucleotide microarray. BMC Genomics (2006) 1.05
Novel antigens in type 1 diabetes: the importance of ZnT8. Curr Diab Rep (2009) 1.05
Cytokine-mediated down-regulation of the transcription factor cAMP-response element-binding protein in pancreatic beta-cells. J Biol Chem (2003) 1.02
Improving protein function prediction methods with integrated literature data. BMC Bioinformatics (2008) 1.02
Protein carbonylation in a murine model for early alcoholic liver disease. Chem Res Toxicol (2012) 1.00
Skeletal muscle proteomics: carbohydrate metabolism oscillates with seasonal and torpor-arousal physiology of hibernation. Am J Physiol Regul Integr Comp Physiol (2011) 0.99
U-Compare bio-event meta-service: compatible BioNLP event extraction services. BMC Bioinformatics (2011) 0.99
ETS-family genes in pancreatic development. Dev Dyn (2007) 0.98
Exploring species-based strategies for gene normalization. IEEE/ACM Trans Comput Biol Bioinform (2010) 0.97
Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human islets. Diabetes (2007) 0.96
Parenthetically speaking: classifying the contents of parentheses for text mining. AMIA Annu Symp Proc (2011) 0.96
Bombesin receptor subtype-3 (BRS-3) regulates glucose-stimulated insulin secretion in pancreatic islets across multiple species. Endocrinology (2011) 0.96
Metabolic cycles in a circannual hibernator. Physiol Genomics (2011) 0.96
The diagnostic value of zinc transporter 8 autoantibody (ZnT8A) for type 1 diabetes in Chinese. Diabetes Metab Res Rev (2010) 0.96
A novel function of MUC18: amplification of lung inflammation during bacterial infection. Am J Pathol (2012) 0.95
Temporal analysis of mRNA and miRNA expression in transgenic mice overexpressing Arg- and Gly389 polymorphic variants of the β1-adrenergic receptor. Physiol Genomics (2011) 0.95
Chapter 16: text mining for translational bioinformatics. PLoS Comput Biol (2013) 0.94
Establishment of native insulin-negative NOD mice and the methodology to distinguish specific insulin knockout genotypes and a B:16 alanine preproinsulin transgene. Ann N Y Acad Sci (2004) 0.94
DNA microarray and proteomic strategies for understanding alcohol action. Alcohol Clin Exp Res (2006) 0.94
Multistate proteomics analysis reveals novel strategies used by a hibernator to precondition the heart and conserve ATP for winter heterothermy. Physiol Genomics (2011) 0.93
A simulated MS/MS library for spectrum-to-spectrum searching in large scale identification of proteins. Mol Cell Proteomics (2008) 0.92
G6PC2: a negative regulator of basal glucose-stimulated insulin secretion. Diabetes (2012) 0.92
Genome-scale identification and characterization of ethanol tolerance genes in Escherichia coli. Metab Eng (2012) 0.91
Identification of a major humoral epitope in Slc30A8 (ZnT8). Ann N Y Acad Sci (2008) 0.91
Recycling of the dense-core vesicle membrane protein phogrin in Min6 beta-cells. Biochem Biophys Res Commun (2004) 0.90
Peax: interactive visual analysis and exploration of complex clinical phenotype and gene expression association. Pac Symp Biocomput (2015) 0.90
An extended tyrosine-targeting motif for endocytosis and recycling of the dense-core vesicle membrane protein phogrin. Traffic (2005) 0.90
Long-range enhancers are required to maintain expression of the autoantigen islet-specific glucose-6-phosphatase catalytic subunit-related protein in adult mouse islets in vivo. Diabetes (2007) 0.89
Predicting protein linkages in bacteria: which method is best depends on task. BMC Bioinformatics (2008) 0.88
Mapping of conformational autoantibody epitopes in ZNT8. Diabetes Metab Res Rev (2011) 0.87
HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes. J Immunol (2004) 0.87
Exact calculations of average power for the Benjamini-Hochberg procedure. Int J Biostat (2008) 0.86
The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer. Biochem J (2011) 0.86
C16:0 sulfatide inhibits insulin secretion in rat beta-cells by reducing the sensitivity of KATP channels to ATP inhibition. Diabetes (2006) 0.85
Profiling impaired hepatic endoplasmic reticulum glycosylation as a consequence of ethanol ingestion. J Proteome Res (2011) 0.85
The topology of the bacterial co-conserved protein network and its implications for predicting protein function. BMC Genomics (2008) 0.85
Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study. Diabetes (2012) 0.84
The lumenal domain of the integral membrane protein phogrin mediates targeting to secretory granules. Traffic (2002) 0.84
HLA-A*24 is an independent predictor of 5-year progression to diabetes in autoantibody-positive first-degree relatives of type 1 diabetic patients. Diabetes (2012) 0.84
Kidney proteome changes provide evidence for a dynamic metabolism and regional redistribution of plasma proteins during torpor-arousal cycles of hibernation. Physiol Genomics (2012) 0.83
Characterization of the human SLC30A8 promoter and intronic enhancer. J Mol Endocrinol (2011) 0.83
Regional differences in subcutaneous adipose tissue gene expression. Obesity (Silver Spring) (2012) 0.83
Combining heterogenous data for prediction of disease related and pharmacogenes. Pac Symp Biocomput (2014) 0.82
New antigenic targets in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes (2008) 0.82
GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist. Exp Diabetes Res (2008) 0.81