Published in Microb Cell Fact on April 03, 2012
Engineering Escherichia coli to synthesize free fatty acids. Trends Biotechnol (2012) 1.28
Next generation biofuel engineering in prokaryotes. Curr Opin Chem Biol (2013) 1.23
Identification of transport proteins involved in free fatty acid efflux in Escherichia coli. J Bacteriol (2012) 1.09
Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels. Biotechnol Biofuels (2014) 1.07
Improved Free Fatty Acid Production in Cyanobacteria with Synechococcus sp. PCC 7002 as Host. Front Bioeng Biotechnol (2014) 1.04
An engineered pathway for the biosynthesis of renewable propane. Nat Commun (2014) 1.00
Systems metabolic engineering design: fatty acid production as an emerging case study. Biotechnol Bioeng (2014) 0.85
Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering. Mol Biosyst (2014) 0.82
Improving fatty acid availability for bio-hydrocarbon production in Escherichia coli by metabolic engineering. PLoS One (2013) 0.79
Production Strategies and Applications of Microbial Single Cell Oils. Front Microbiol (2016) 0.76
In silico screening for candidate chassis strains of free fatty acid-producing cyanobacteria. BMC Genomics (2017) 0.75
Genetic engineering of microorganisms for biodiesel production. Bioengineered (2012) 0.75
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass. Nature (2010) 5.84
Challenges in engineering microbes for biofuels production. Science (2007) 3.05
Fatty acid production in genetically modified cyanobacteria. Proc Natl Acad Sci U S A (2011) 2.77
Perspectives of microbial oils for biodiesel production. Appl Microbiol Biotechnol (2008) 2.25
Alteration of the specificity and regulation of fatty acid synthesis of Escherichia coli by expression of a plant medium-chain acyl-acyl carrier protein thioesterase. J Bacteriol (1994) 2.12
Overproduction of acetyl-CoA carboxylase activity increases the rate of fatty acid biosynthesis in Escherichia coli. J Biol Chem (2000) 2.05
Overproduction of free fatty acids in E. coli: implications for biodiesel production. Metab Eng (2008) 1.97
A process for microbial hydrocarbon synthesis: Overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes. Biotechnol Bioeng (2010) 1.88
Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnol Bioeng (1996) 1.86
Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis. J Bacteriol (1993) 1.80
Penicillin-binding protein PBP2 of Escherichia coli localizes preferentially in the lateral wall and at mid-cell in comparison with the old cell pole. Mol Microbiol (2003) 1.80
Inhibition of fatty acid synthesis in Escherichia coli in the absence of phospholipid synthesis and release of inhibition by thioesterase action. J Bacteriol (1994) 1.76
Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. Metab Eng (2000) 1.75
Introduction to advantages and problems of shaken cultures. Biochem Eng J (2001) 1.74
MsbA transporter-dependent lipid A 1-dephosphorylation on the periplasmic surface of the inner membrane: topography of francisella novicida LpxE expressed in Escherichia coli. J Biol Chem (2004) 1.73
Recovery of microalgal biomass and metabolites: process options and economics. Biotechnol Adv (2003) 1.71
Defective export of a periplasmic enzyme disrupts regulation of fatty acid synthesis. J Biol Chem (1995) 1.69
Stabilized gene duplication enables long-term selection-free heterologous pathway expression. Nat Biotechnol (2009) 1.65
Escherichia coli unsaturated fatty acid synthesis: complex transcription of the fabA gene and in vivo identification of the essential reaction catalyzed by FabB. J Biol Chem (2009) 1.63
Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification. Microbiol Mol Biol Rev (2003) 1.55
Quantitative analysis and engineering of fatty acid biosynthesis in E. coli. Metab Eng (2010) 1.55
Escherichia coli thioesterase I, molecular cloning and sequencing of the structural gene and identification as a periplasmic enzyme. J Biol Chem (1993) 1.47
Fatty acid transport proteins: a current view of a growing family. Trends Endocrinol Metab (2001) 1.44
Penicillin-binding proteins. Wall peptidoglycan assembly and resistance to penicillin: facts, doubts and hopes. Int J Antimicrob Agents (1997) 1.37
Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A. J Biol Chem (2000) 1.36
Transport of long-chain fatty acids in Escherichia coli. Evidence for role of fadL gene product as long-chain fatty acid receptor. J Biol Chem (1986) 1.12
Temperature effect on inclusion body formation and stress response in the periplasm of Escherichia coli. Mol Microbiol (2003) 1.08
Effect of temperature on protein quality in bacterial inclusion bodies. FEBS Lett (2006) 1.05
Metabolic engineering of microorganisms: general strategies and drug production. Drug Discov Today (2008) 1.04
Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling. FEBS J (2008) 1.02
A host/plasmid system that is not dependent on antibiotics and antibiotic resistance genes for stable plasmid maintenance in Escherichia coli. J Biotechnol (2004) 1.01
High butanol production by Clostridium saccharoperbutylacetonicum N1-4 in fed-batch culture with pH-Stat continuous butyric acid and glucose feeding method. J Biosci Bioeng (2004) 0.97
Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology. Metab Eng (2009) 0.90
Integrated processing of biotechnology products. Biotechnol Adv (2000) 0.86
Improvement in the Iatroscan thin-layer chromatographic-flame ionisation detection analysis of marine lipids. Separation and quantitation of monoacylglycerols and diacylglycerols in standards and natural samples. J Chromatogr A (1999) 0.83
Integrated bioprocesses. Curr Opin Microbiol (2005) 0.79
Integrated L-phenylalanine separation in an E. coli fed-batch process: from laboratory to pilot scale. Bioprocess Biosyst Eng (2002) 0.77
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell (2010) 15.20
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med (2009) 10.54
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (2010) 10.30
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature (2006) 9.20
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature (2011) 6.73
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA (2008) 6.60
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (2010) 5.86
Structure of the human κ-opioid receptor in complex with JDTic. Nature (2012) 5.18
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science (2013) 5.10
JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A (2009) 4.98
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet (2009) 4.35
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med (2005) 4.17
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science (2013) 3.72
Structure of the human histamine H1 receptor complex with doxepin. Nature (2011) 3.48
Acquired resistance to crizotinib from a mutation in CD74-ROS1. N Engl J Med (2013) 3.42
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci (2010) 3.38
Structure of the human smoothened receptor bound to an antitumour agent. Nature (2013) 3.08
A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. J Clin Invest (2009) 3.03
Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics. Nature (2013) 2.98
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature (2012) 2.96
Structure of the human glucagon class B G-protein-coupled receptor. Nature (2013) 2.86
Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma. Cancer Res (2008) 2.75
Genomic epidemiology of a dengue virus epidemic in urban Singapore. J Virol (2009) 2.74
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci U S A (2008) 2.70
Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood (2002) 2.66
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol (2004) 2.65
Structural features for functional selectivity at serotonin receptors. Science (2013) 2.60
Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. J Lipid Res (2005) 2.56
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J Clin Invest (2002) 2.52
Risk factors for human illness with avian influenza A (H5N1) virus infection in China. J Infect Dis (2009) 2.50
Crystal structure of a soluble CD28-Fab complex. Nat Immunol (2005) 2.46
Task-dependent visual-codebook compression. IEEE Trans Image Process (2011) 2.44
Glycoprotein structural genomics: solving the glycosylation problem. Structure (2007) 2.40
Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell (2013) 2.40
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res (2008) 2.38
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell (2009) 2.32
Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2003) 2.30
A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs. J Infect Dis (2007) 2.22
An adenosine nucleoside inhibitor of dengue virus. Proc Natl Acad Sci U S A (2009) 2.20
Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nat Genet (2006) 2.19
Rapid transmission of hepatitis C virus among young injecting heroin users in Southern China. Int J Epidemiol (2004) 2.19
The Calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol (2002) 2.18
AnimalTFDB: a comprehensive animal transcription factor database. Nucleic Acids Res (2011) 2.15
Epidermal growth factor receptor mutations and their correlation with gefitinib therapy in patients with non-small cell lung cancer: a meta-analysis based on updated individual patient data from six medical centers in mainland China. J Thorac Oncol (2007) 2.15
Serologic survey of pandemic (H1N1) 2009 virus, Guangxi Province, China. Emerg Infect Dis (2009) 2.13
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab (2008) 2.10
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (2012) 2.08
Quantitative hepatic CT perfusion measurement: comparison of Couinaud's hepatic segments with dual-source 128-slice CT. Eur J Radiol (2012) 2.06
Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure. Toxicol Lett (2009) 2.04
LysM-type mycorrhizal receptor recruited for rhizobium symbiosis in nonlegume Parasponia. Science (2010) 2.02
Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. BMC Cell Biol (2008) 2.00
Sensorineural hearing loss associated with neomycin eardrops and nonintact tympanic membranes. Otolaryngol Head Neck Surg (2012) 1.98
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol (2008) 1.97
Small molecule activation of PKM2 in cancer cells induces serine auxotrophy. Chem Biol (2012) 1.96
MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med (Berl) (2008) 1.93
Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res (2003) 1.92
A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
Regional ventricular wall thickening reflects changes in cardiac fiber and sheet structure during contraction: quantification with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2005) 1.91
Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42. Biochemistry (2006) 1.88
Comparison of helix interactions in membrane and soluble alpha-bundle proteins. Biophys J (2002) 1.88
Structural basis for molecular recognition at serotonin receptors. Science (2013) 1.86
'Social evils' and harm reduction: the evolving policy environment for human immunodeficiency virus prevention among injection drug users in China and Vietnam. Addiction (2007) 1.85
The calcimimetic AMG 073 reduces parathyroid hormone and calcium x phosphorus in secondary hyperparathyroidism. Kidney Int (2003) 1.82
Insect outbreaks produce distinctive carbon isotope signatures in defensive resins and fossiliferous ambers. Proc Biol Sci (2011) 1.75
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity. Proc Natl Acad Sci U S A (2012) 1.74
Golgi inheritance in mammalian cells is mediated through endoplasmic reticulum export activities. Mol Biol Cell (2005) 1.73
MRI features of pigmented villonodular synovitis (PVNS). Clin Rheumatol (2004) 1.73
Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells. Cell (2012) 1.72
A five-city trial of a behavioural intervention to reduce sexually transmitted disease/HIV risk among sex workers in China. AIDS (2007) 1.72
Identification of Francisella tularensis genes affected by iron limitation. Infect Immun (2006) 1.72
The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. PLoS One (2009) 1.72
trans-Diaqua-bis[5-carb-oxy-4-carboxyl-ato-2-(4-pyridinio)-1H-imidazol-1-ido-κN,O]iron(II). Acta Crystallogr Sect E Struct Rep Online (2009) 1.72
Cellular magnetic resonance imaging: current status and future prospects. Expert Rev Med Devices (2006) 1.71
The adult Drosophila malpighian tubules are maintained by multipotent stem cells. Cell Stem Cell (2007) 1.70
Acupuncture for essential hypertension. Int J Cardiol (2013) 1.70
Cinacalcet hydrochloride is an effective treatment for secondary hyperparathyroidism in patients with CKD not receiving dialysis. Am J Kidney Dis (2005) 1.69
Soluble syndecan-1 promotes growth of myeloma tumors in vivo. Blood (2002) 1.69
MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G. Cancer Lett (2008) 1.68
Condom use among female sex workers in China: role of gatekeepers. Sex Transm Dis (2005) 1.67
Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell (2013) 1.66
MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2. Gastroenterology (2012) 1.64
Cholesterol biosynthesis modulation regulates dengue viral replication. Virology (2009) 1.64
Density-functional theory with screened van der Waals interactions for the modeling of hybrid inorganic-organic systems. Phys Rev Lett (2012) 1.63
Isolation and characterization of cancer stem like cells in human glioblastoma cell lines. Cancer Lett (2009) 1.62
Detecting and profiling tissue-selective genes. Physiol Genomics (2006) 1.61
A genomic and expression compendium of the expanded PEBP gene family from maize. Plant Physiol (2007) 1.61
High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. Nucleic Acids Res (2013) 1.61
Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development (2002) 1.60
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet (2007) 1.59
Climate variability and hemorrhagic fever with renal syndrome transmission in Northeastern China. Environ Health Perspect (2010) 1.59
New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol (2009) 1.58
A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation. J Biol Chem (2011) 1.57
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell (2008) 1.57
Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2. Int Immunopharmacol (2004) 1.56