PubRank

J W Sedat

Author PubWeight™ 173.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 2000 6.93
2 Fluorescence microscopy in three dimensions. Methods Cell Biol 1989 6.70
3 Fluorescence microscopy: reduced photobleaching of rhodamine and fluorescein protein conjugates by n-propyl gallate. Science 1982 5.92
4 Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA. Mol Biol Cell 1997 5.47
5 Mitosis in living budding yeast: anaphase A but no metaphase plate. Science 1997 5.15
6 Interphase chromosomes undergo constrained diffusional motion in living cells. Curr Biol 1997 5.00
7 I5M: 3D widefield light microscopy with better than 100 nm axial resolution. J Microsc 1999 4.84
8 Perturbation of nuclear architecture by long-distance chromosome interactions. Cell 1996 4.73
9 Direct evidence of a role for heterochromatin in meiotic chromosome segregation. Cell 1996 4.53
10 Microtubule nucleation by gamma-tubulin-containing rings in the centrosome. Nature 1995 4.24
11 Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity 2001 3.84
12 Three-dimensional architecture of a polytene nucleus. Nature 1983 3.82
13 Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA. Nat New Biol 1973 3.74
14 Spatial control of actin polymerization during neutrophil chemotaxis. Nat Cell Biol 1999 3.45
15 Determination of three-dimensional imaging properties of a light microscope system. Partial confocal behavior in epifluorescence microscopy. Biophys J 1990 3.44
16 Structure of the DNA of bacteriophage phiX174. VII. Methylation. J Mol Biol 1970 3.23
17 Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast. J Cell Biol 1998 2.97
18 Large-scale chromatin structural domains within mitotic and interphase chromosomes in vivo and in vitro. Chromosoma 1989 2.66
19 Block in anaphase chromosome separation caused by a telomerase template mutation. Science 1997 2.65
20 Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nat Cell Biol 1999 2.65
21 The use of a charge-coupled device for quantitative optical microscopy of biological structures. Science 1987 2.64
22 Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. Mol Biol Cell 1999 2.61
23 Three-dimensional multiple-wavelength fluorescence microscopy for the structural analysis of biological phenomena. Semin Cell Biol 1991 2.43
24 Three-dimensional structural characterization of centrosomes from early Drosophila embryos. J Cell Biol 1995 2.41
25 Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster. J Cell Biol 1986 2.39
26 Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr Biol 2001 2.37
27 Meiotic chromosome pairing in maize is associated with a novel chromatin organization. Cell 1994 2.34
28 Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster. Mol Biol Cell 1996 2.32
29 Interphase nuclear envelope lamins form a discontinuous network that interacts with only a fraction of the chromatin in the nuclear periphery. Cell 1990 2.32
30 The onset of homologous chromosome pairing during Drosophila melanogaster embryogenesis. J Cell Biol 1993 2.26
31 A three-dimensional approach to mitotic chromosome structure: evidence for a complex hierarchical organization. J Cell Biol 1987 2.26
32 Telomeres cluster de novo before the initiation of synapsis: a three-dimensional spatial analysis of telomere positions before and during meiotic prophase. J Cell Biol 1997 2.17
33 Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations. J Cell Biol 1998 2.16
34 IVE (Image Visualization Environment): a software platform for all three-dimensional microscopy applications. J Struct Biol 1996 2.12
35 Phase-retrieved pupil functions in wide-field fluorescence microscopy. J Microsc 2004 1.96
36 Fractionation of nucleic acid on benzoylated-naphthoylated DEAE cellulose. J Mol Biol 1967 1.92
37 Computational adaptive optics for live three-dimensional biological imaging. Proc Natl Acad Sci U S A 2001 1.91
38 Dispersion, aberration and deconvolution in multi-wavelength fluorescence images. J Microsc 1996 1.89
39 Multiple chromosomal populations of topoisomerase II detected in vivo by time-lapse, three-dimensional wide-field microscopy. Cell 1993 1.87
40 The three-dimensional architecture of chromatin in situ: electron tomography reveals fibers composed of a continuously variable zig-zag nucleosomal ribbon. J Cell Biol 1994 1.84
41 Temporal and spatial coordination of chromosome movement, spindle formation, and nuclear envelope breakdown during prometaphase in Drosophila melanogaster embryos. J Cell Biol 1990 1.80
42 Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. J Cell Biol 1988 1.59
43 Three-dimensional organization of Drosophila melanogaster interphase nuclei. II. Chromosome spatial organization and gene regulation. J Cell Biol 1987 1.58
44 Automated microscopy for electron tomography. Ultramicroscopy 1992 1.56
45 Mapping three-dimensional chromosome architecture in situ. Methods Cell Biol 1998 1.51
46 A novel 3D wavelet-based filter for visualizing features in noisy biological data. J Microsc 2005 1.50
47 Focal points for chromosome condensation and decondensation revealed by three-dimensional in vivo time-lapse microscopy. Nature 1989 1.48
48 Three-dimensional organization of Drosophila melanogaster interphase nuclei. I. Tissue-specific aspects of polytene nuclear architecture. J Cell Biol 1987 1.46
49 Direct cell lineage analysis in Drosophila melanogaster by time-lapse, three-dimensional optical microscopy of living embryos. J Cell Biol 1989 1.45
50 Spatial organization of the Drosophila nucleus: a three-dimensional cytogenetic study. J Cell Sci Suppl 1984 1.44
51 Evidence for the coincident initiation of homolog pairing and synapsis during the telomere-clustering (bouquet) stage of meiotic prophase. J Cell Sci 2000 1.39
52 Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos by four-dimensional microscopy-based motion analysis. Curr Biol 2001 1.38
53 Proteins shifting from the cytoplasm into the nuclei during early embryogenesis of Drosophila melanogaster. Dev Biol 1984 1.37
54 Rapid isolation of metaphase chromosomes containing high molecular weight DNA. J Cell Biol 1979 1.35
55 Cryo automated electron tomography: towards high-resolution reconstructions of plastic-embedded structures. J Microsc 1994 1.23
56 Precise determination of the molecular limits of a polytene chromosome band: regulatory sequences for the Notch gene are in the interband. Cell 1988 1.19
57 Tilted view reconstruction in optical microscopy. Three-dimensional reconstruction of Drosophila melanogaster embryo nuclei. Biophys J 1989 1.19
58 Deconstructing the nucleus: global architecture from local interactions. Curr Opin Genet Dev 1997 1.17
59 Drosophila gastrulation: analysis of cell shape changes in living embryos by three-dimensional fluorescence microscopy. Development 1991 1.14
60 Time-resolved, in vivo studies of mitotic spindle formation and nuclear lamina breakdown in Drosophila early embryos. J Cell Sci 1996 1.11
61 Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190. J Cell Sci 1997 1.10
62 In vivo methylation of replicating bacteriophage phi chi174 DNA. J Mol Biol 1973 1.09
63 A three-dimensional structural dissection of Drosophila polytene chromosomes. J Cell Biol 1995 1.06
64 Selective loss of sperm bearing a compound chromosome in the Drosophila female. Genetics 1996 1.01
65 Solid-state imagers for microscopy. Methods Cell Biol 1989 0.99
66 High-resolution wide-field microscopy with adaptive optics for spherical aberration correction and motionless focusing. J Microsc 2010 0.98
67 The three-dimensional organization of polytene nuclei in male Drosophila melanogaster with compound XY or ring X chromosomes. Genetics 1989 0.94
68 Light microscope based analysis of three-dimensional structure: applications to the study of Drosophila salivary gland nuclei. I. Data collection and analysis. J Microsc 1985 0.93
69 A library of monoclonal antibodies to nuclear proteins from Drosophila melanogaster embryos. Characterization by a cultured cell assay. Exp Cell Res 1982 0.91
70 Toward fully automated high-resolution electron tomography. J Struct Biol 1996 0.91
71 Chromosome structure inside the nucleus. Curr Opin Cell Biol 1993 0.88
72 Automated data collection for electron microscopic tomography. Methods Enzymol 2010 0.86
73 Three-dimensional light microscopy of diploid Drosophila chromosomes. Cell Motil Cytoskeleton 1988 0.85
74 Practical image restoration of thick biological specimens using multiple focus levels in transmission electron microscopy. J Struct Biol 1997 0.82
75 Gene F of bacteriophage phiX174. Correlation of nucleotide sequences from the DNA and amino acid sequences from the gene product. J Mol Biol 1976 0.82
76 Structure of Drosophila polytene chromosomes. Evidence for a toroidal organization of the bands. J Cell Sci 1982 0.81
77 Optimal strategies for imaging thick biological specimens: exit wavefront reconstruction and energy-filtered imaging. J Microsc 1996 0.81
78 Nuclear architecture. Results Probl Cell Differ 1999 0.80
79 Mechanism of image formation for thick biological specimens: exit wavefront reconstruction and electron energy-loss spectroscopic imaging. J Microsc 1995 0.79
80 Interferometer-based structured-illumination microscopy utilizing complementary phase relationship through constructive and destructive image detection by two cameras. J Microsc 2012 0.75
81 An extended view of nuclear lamin structure, function, and dynamics. Semin Cell Biol 1992 0.75