Published in Cardiovasc Res on April 02, 2012
Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunits. Front Physiol (2014) 0.88
An update to the toxicological profile for water-soluble and sparingly soluble tungsten substances. Crit Rev Toxicol (2015) 0.81
Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans. J Clin Cell Immunol (2015) 0.79
BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating. Pflugers Arch (2013) 0.79
Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle. PLoS One (2015) 0.78
Heavy metal to lower the pressure? Cardiovasc Res (2012) 0.77
BK channels in rat and human pulmonary smooth muscle cells are BKα-β1 functional complexes lacking the oxygen-sensitive stress axis regulated exon insert. Pulm Circ (2016) 0.75
Environmental justice and regional inequality in southern California: implications for future research. Environ Health Perspect (2002) 2.60
The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Hum Mol Genet (2010) 1.83
Near-roadway pollution and childhood asthma: implications for developing "win-win" compact urban development and clean vehicle strategies. Environ Health Perspect (2012) 1.73
Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension. J Clin Invest (2004) 1.70
TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity. J Cell Biol (2005) 1.68
Inroads to predict in vivo toxicology-an introduction to the eTOX Project. Int J Mol Sci (2012) 1.64
Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking. J Biol Chem (2005) 1.61
Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction. Circ Res (2011) 1.60
Playing it safe: assessing cumulative impact and social vulnerability through an environmental justice screening method in the South Coast Air Basin, California. Int J Environ Res Public Health (2011) 1.54
A multiscale simulation system for the prediction of drug-induced cardiotoxicity. J Chem Inf Model (2011) 1.38
TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. Proc Natl Acad Sci U S A (2008) 1.36
Ambient air pollution exposure and full-term birth weight in California. Environ Health (2010) 1.35
Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel. J Gen Physiol (2006) 1.33
A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis. J Biol Chem (2011) 1.33
Anchor-GRIND: filling the gap between standard 3D QSAR and the GRid-INdependent descriptors. J Med Chem (2005) 1.26
A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia. Proc Natl Acad Sci U S A (2009) 1.25
Induced effects of sodium ions on dopaminergic G-protein coupled receptors. PLoS Comput Biol (2010) 1.25
Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia. J Biol Chem (2004) 1.22
IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid. J Cell Biol (2008) 1.22
Genetic variation in the KCNMA1 potassium channel alpha subunit as risk factor for severe essential hypertension and myocardial infarction. J Hypertens (2008) 1.19
Maxi K+ channel mediates regulatory volume decrease response in a human bronchial epithelial cell line. Am J Physiol Cell Physiol (2002) 1.19
Mechanisms of low-glucose sensitivity in carotid body glomus cells. Diabetes (2007) 1.18
Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk. Circ Res (2005) 1.16
Strengthening community capacity to participate in making decisions to reduce disproportionate environmental exposures. Am J Public Health (2011) 1.12
RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration. Hum Mol Genet (2007) 1.10
Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma. J Biol Chem (2010) 1.08
Association between self-replicating calcifying nanoparticles and aortic stenosis: a possible link to valve calcification. Eur Heart J (2008) 1.08
Scientific competency questions as the basis for semantically enriched open pharmacological space development. Drug Discov Today (2013) 1.04
Transient receptor potential genes, smoking, occupational exposures and cough in adults. Respir Res (2012) 1.02
Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli. Proc Natl Acad Sci U S A (2013) 0.99
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation. Brain (2009) 0.96
Ca2+ channel-sarcoplasmic reticulum coupling: a mechanism of arterial myocyte contraction without Ca2+ influx. EMBO J (2003) 0.96
IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site. J Biol Chem (2008) 0.96
Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells. Neurobiol Aging (2007) 0.94
The TRPV4 channel. Handb Exp Pharmacol (2014) 0.94
ORMDL3 modulates store-operated calcium entry and lymphocyte activation. Hum Mol Genet (2012) 0.93
Late-onset episodic ataxia type 2 associated with a novel loss-of-function mutation in the CACNA1A gene. J Neurol Sci (2009) 0.93
Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines. Pflugers Arch (2008) 0.92
Plasma membrane voltage-dependent anion channel mediates antiestrogen-activated maxi Cl- currents in C1300 neuroblastoma cells. J Biol Chem (2003) 0.92
Development and validation of AMANDA, a new algorithm for selecting highly relevant regions in Molecular Interaction Fields. J Chem Inf Model (2008) 0.92
Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCR. PLoS One (2012) 0.91
Equine estrogens impair nitric oxide production and endothelial nitric oxide synthase transcription in human endothelial cells compared with the natural 17{beta}-estradiol. Hypertension (2010) 0.91
A review of TRP channels splicing. Semin Cell Dev Biol (2006) 0.89
Cell membrane stretch modulates the high-conductance Ca2+-activated K+ channel in bovine trabecular meshwork cells. Invest Ophthalmol Vis Sci (2003) 0.88
The progesterone receptor regulates the expression of TRPV4 channel. Pflugers Arch (2009) 0.87
Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis. PLoS One (2013) 0.87
Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia. J Biol Chem (2012) 0.86
MEMBPLUGIN: studying membrane complexity in VMD. Bioinformatics (2014) 0.86
Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor. J Med Chem (2007) 0.85
Applicability Domain ANalysis (ADAN): a robust method for assessing the reliability of drug property predictions. J Chem Inf Model (2014) 0.85
A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction. Cardiovasc Res (2011) 0.84
A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis. Proc Natl Acad Sci U S A (2010) 0.83
Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands. Bioorg Med Chem Lett (2009) 0.83
QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine. Neuropharmacology (2006) 0.83
Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant. J Neurosci (2002) 0.83
Voltage-dependent anion channel localises to the plasma membrane and peripheral but not perinuclear mitochondria. Pflugers Arch (2003) 0.82
The haves, the have-nots, and the health of everyone: the relationship between social inequality and environmental quality. Annu Rev Public Health (2015) 0.82
Surface descriptors for protein-ligand affinity prediction. J Med Chem (2003) 0.82
Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design. Curr Pharm Des (2013) 0.82
Suitability of GRIND-based principal properties for the description of molecular similarity and ligand-based virtual screening. J Chem Inf Model (2009) 0.82
Chloride secretion in a morphologically differentiated human colonic cell line that expresses the epithelial Na+ channel. J Physiol (2003) 0.82
The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition. Pflugers Arch (2009) 0.82
Multi-receptor binding profile of clozapine and olanzapine: a structural study based on the new beta2 adrenergic receptor template. ChemMedChem (2008) 0.82
Incorporating molecular shape into the alignment-free Grid-Independent Descriptors. J Med Chem (2004) 0.82
Hypoxia inducible factor-2alpha stabilization and maxi-K+ channel beta1-subunit gene repression by hypoxia in cardiac myocytes: role in preconditioning. Circ Res (2009) 0.81
IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid. J Gen Physiol (2008) 0.80
Rational design of the survivin/CDK4 complex by combining protein-protein docking and molecular dynamics simulations. J Mol Model (2012) 0.80
Nitro-oxidative stress after neuronal ischemia induces protein nitrotyrosination and cell death. Oxid Med Cell Longev (2013) 0.80
Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling. Br J Pharmacol (2012) 0.80
Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II. ACS Chem Biol (2014) 0.80
Hypoxia inhibits vasoconstriction induced by metabotropic Ca2+ channel-induced Ca2+ release in mammalian coronary arteries. Cardiovasc Res (2009) 0.80
Short communication: genetic ablation of L-type Ca2+ channels abolishes depolarization-induced Ca2+ release in arterial smooth muscle. Circ Res (2010) 0.79
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory. J Membr Biol (2015) 0.79
Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors. ChemMedChem (2010) 0.79
BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating. Pflugers Arch (2013) 0.79
Tonic arterial contraction mediated by L-type Ca2+ channels requires sustained Ca2+ influx, G protein-associated Ca2+ release, and RhoA/ROCK activation. Eur J Pharmacol (2012) 0.79