|
1
|
Common variants on chromosome 6p22.1 are associated with schizophrenia.
|
Nature
|
2009
|
8.12
|
|
2
|
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
|
Nat Genet
|
2013
|
8.02
|
|
3
|
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
Nat Genet
|
2013
|
7.44
|
|
4
|
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
|
Lancet
|
2012
|
4.87
|
|
5
|
Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications.
|
Am J Psychiatry
|
2011
|
4.29
|
|
6
|
A HaemAtlas: characterizing gene expression in differentiated human blood cells.
|
Blood
|
2009
|
3.63
|
|
7
|
Evaluation of Nyholt's procedure for multiple testing correction.
|
Hum Hered
|
2005
|
2.50
|
|
8
|
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.
|
Blood
|
2009
|
2.25
|
|
9
|
The use of edge-betweenness clustering to investigate biological function in protein interaction networks.
|
BMC Bioinformatics
|
2005
|
1.97
|
|
10
|
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.
|
Eur J Hum Genet
|
2009
|
1.97
|
|
11
|
Maximizing association statistics over genetic models.
|
Genet Epidemiol
|
2008
|
1.93
|
|
12
|
Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins.
|
Blood
|
2006
|
1.91
|
|
13
|
Research review: Polygenic methods and their application to psychiatric traits.
|
J Child Psychol Psychiatry
|
2014
|
1.54
|
|
14
|
Copy number variation of the APC gene is associated with regulation of bone mineral density.
|
Bone
|
2012
|
1.46
|
|
15
|
Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins.
|
Blood
|
2008
|
1.45
|
|
16
|
A note on permutation tests in multistage association scans.
|
Am J Hum Genet
|
2006
|
1.28
|
|
17
|
Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort.
|
Eur J Hum Genet
|
2006
|
1.25
|
|
18
|
Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function.
|
Blood
|
2010
|
1.16
|
|
19
|
Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.
|
Am J Psychiatry
|
2012
|
1.15
|
|
20
|
Re: Is the Risk Difference Really a More Heterogeneous Measure?
|
Epidemiology
|
2016
|
1.08
|
|
21
|
What role for genetics in the prediction of multiple sclerosis?
|
Ann Neurol
|
2010
|
1.05
|
|
22
|
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.
|
Eur J Hum Genet
|
2009
|
1.05
|
|
23
|
Genome-wide association study of multiplex schizophrenia pedigrees.
|
Am J Psychiatry
|
2012
|
1.05
|
|
24
|
Comparison of methods for competitive tests of pathway analysis.
|
PLoS One
|
2012
|
1.03
|
|
25
|
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
|
PLoS One
|
2013
|
1.02
|
|
26
|
Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents.
|
Br J Psychiatry
|
2010
|
1.01
|
|
27
|
Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia.
|
PLoS One
|
2009
|
1.00
|
|
28
|
Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.
|
Genet Epidemiol
|
2009
|
0.98
|
|
29
|
9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.95
|
|
30
|
Genetic determinants of major blood lipids in Pakistanis compared with Europeans.
|
Circ Cardiovasc Genet
|
2010
|
0.95
|
|
31
|
Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis.
|
Int J Epidemiol
|
2012
|
0.95
|
|
32
|
Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis.
|
Am J Hum Genet
|
2008
|
0.94
|
|
33
|
An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD.
|
Am J Med Genet B Neuropsychiatr Genet
|
2007
|
0.93
|
|
34
|
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
|
Int J Epidemiol
|
2015
|
0.93
|
|
35
|
Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men.
|
PLoS Genet
|
2011
|
0.92
|
|
36
|
Polymorphism in HSD17B6 is associated with key features of polycystic ovary syndrome.
|
Fertil Steril
|
2006
|
0.91
|
|
37
|
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes.
|
Hum Genet
|
2003
|
0.91
|
|
38
|
Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis.
|
Bone
|
2009
|
0.90
|
|
39
|
Utilising family-based designs for detecting rare variant disease associations.
|
Ann Hum Genet
|
2014
|
0.88
|
|
40
|
Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.
|
Neurobiol Aging
|
2012
|
0.88
|
|
41
|
Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.
|
PLoS One
|
2013
|
0.87
|
|
42
|
Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI.
|
Hum Mol Genet
|
2012
|
0.87
|
|
43
|
Early and current socio-economic position and cardiometabolic risk factors in the Indian Migration Study.
|
Eur J Prev Cardiol
|
2012
|
0.87
|
|
44
|
A general framework for two-stage analysis of genome-wide association studies and its application to case-control studies.
|
Am J Hum Genet
|
2012
|
0.87
|
|
45
|
Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores.
|
Genet Epidemiol
|
2013
|
0.85
|
|
46
|
Two novel pathway analysis methods based on a hierarchical model.
|
Bioinformatics
|
2013
|
0.84
|
|
47
|
Identification of variation in the platelet transcriptome associated with glycoprotein 6 haplotype.
|
Platelets
|
2008
|
0.84
|
|
48
|
Fast and robust association tests for untyped SNPs in case-control studies.
|
Hum Hered
|
2010
|
0.84
|
|
49
|
Evaluation of seven common lipid associated loci in a large Indian sib pair study.
|
Lipids Health Dis
|
2012
|
0.82
|
|
50
|
Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro.
|
J Bone Miner Res
|
2009
|
0.80
|
|
51
|
Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal.
|
BMC Genet
|
2013
|
0.80
|
|
52
|
Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia.
|
BMC Genet
|
2010
|
0.80
|
|
53
|
Heritability of Individual Psychotic Experiences Captured by Common Genetic Variants in a Community Sample of Adolescents.
|
Behav Genet
|
2015
|
0.79
|
|
54
|
Transmission of human herpesvirus type 8 infection within families in american indigenous populations from the Brazilian Amazon.
|
J Infect Dis
|
2012
|
0.78
|
|
55
|
Accuracy of Gene Scores when Pruning Markers by Linkage Disequilibrium.
|
Hum Hered
|
2016
|
0.78
|
|
56
|
Erratum: Whole-genome sequence-based analysis of thyroid function.
|
Nat Commun
|
2015
|
0.77
|
|
57
|
Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations.
|
Comput Biol Chem
|
2007
|
0.76
|
|
58
|
Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome.
|
Fertil Steril
|
2008
|
0.76
|
|
59
|
Commentary: Tobacco consumption and body weight: Mendelian randomization across a range of exposure.
|
Int J Epidemiol
|
2015
|
0.75
|
|
60
|
Application of the optimal discovery procedure to genetic case-control studies: comparison with p values and asymptotic Bayes factors.
|
Hum Hered
|
2011
|
0.75
|