Published in BMC Genet on September 09, 2010
HapFABIA: identification of very short segments of identity by descent characterized by rare variants in large sequencing data. Nucleic Acids Res (2013) 0.86
Imputation without doing imputation: a new method for the detection of non-genotyped causal variants. Genet Epidemiol (2014) 0.79
Chapter 10: Mining genome-wide genetic markers. PLoS Comput Biol (2012) 0.78
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Genomic control for association studies. Biometrics (1999) 64.39
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol (1995) 30.55
Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat Genet (2005) 25.34
Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. Am J Hum Genet (2007) 24.68
A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol (1996) 20.25
Personal genomes: The case of the missing heritability. Nature (2008) 19.56
A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity. Genetica (1995) 18.06
Calibrating a coalescent simulation of human genome sequence variation. Genome Res (2005) 15.04
Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Hum Hered (2003) 14.37
A tutorial on statistical methods for population association studies. Nat Rev Genet (2006) 12.49
Estimation of significance thresholds for genomewide association scans. Genet Epidemiol (2008) 8.88
Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered (2002) 8.64
A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes. Am J Hum Genet (2001) 8.47
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry (2007) 7.00
Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered (2008) 5.89
The power of genomic control. Am J Hum Genet (2000) 4.99
Use of unphased multilocus genotype data in indirect association studies. Genet Epidemiol (2004) 4.51
Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. Am J Hum Genet (2004) 4.44
Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals. Hum Hered (2003) 4.34
Transmission/disequilibrium tests for extended marker haplotypes. Am J Hum Genet (1999) 4.07
Missing data imputation and haplotype phase inference for genome-wide association studies. Hum Genet (2008) 3.65
Accounting for haplotype uncertainty in matched association studies: a comparison of simple and flexible techniques. Genet Epidemiol (2005) 3.44
Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol (2008) 3.26
Fine mapping of disease genes via haplotype clustering. Genet Epidemiol (2006) 1.82
A flexible Bayesian framework for modeling haplotype association with disease, allowing for dominance effects of the underlying causative variants. Am J Hum Genet (2006) 1.70
Estimation and testing of genotype and haplotype effects in case-control studies: comparison of weighted regression and multiple imputation procedures. Genet Epidemiol (2006) 1.59
Genetic association mapping via evolution-based clustering of haplotypes. PLoS Genet (2007) 1.56
A kinship-based modification of the armitage trend test to address hidden population structure and small differential genotyping errors. PLoS One (2009) 1.50
Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods. BMC Genet (2005) 0.88
Measuring and partitioning the high-order linkage disequilibrium by multiple order Markov chains. Genet Epidemiol (2008) 0.85
One degree of freedom for dominance in indirect association studies. Genet Epidemiol (2007) 0.84
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry (2011) 4.29
A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood (2009) 3.63
Evaluation of Nyholt's procedure for multiple testing correction. Hum Hered (2005) 2.50
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood (2009) 2.25
The use of edge-betweenness clustering to investigate biological function in protein interaction networks. BMC Bioinformatics (2005) 1.97
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet (2009) 1.97
Maximizing association statistics over genetic models. Genet Epidemiol (2008) 1.93
Research review: Polygenic methods and their application to psychiatric traits. J Child Psychol Psychiatry (2014) 1.54
Copy number variation of the APC gene is associated with regulation of bone mineral density. Bone (2012) 1.46
Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins. Blood (2008) 1.45
A note on permutation tests in multistage association scans. Am J Hum Genet (2006) 1.28
Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort. Eur J Hum Genet (2006) 1.25
Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. Blood (2010) 1.16
Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. Am J Psychiatry (2012) 1.15
Re: Is the Risk Difference Really a More Heterogeneous Measure? Epidemiology (2016) 1.08
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. Eur J Hum Genet (2009) 1.05
What role for genetics in the prediction of multiple sclerosis? Ann Neurol (2010) 1.05
Genome-wide association study of multiplex schizophrenia pedigrees. Am J Psychiatry (2012) 1.05
Comparison of methods for competitive tests of pathway analysis. PLoS One (2012) 1.03
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS One (2013) 1.02
Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents. Br J Psychiatry (2010) 1.01
Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia. PLoS One (2009) 1.00
Unbiased estimation of odds ratios: combining genomewide association scans with replication studies. Genet Epidemiol (2009) 0.98
9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev (2012) 0.95
Genetic determinants of major blood lipids in Pakistanis compared with Europeans. Circ Cardiovasc Genet (2010) 0.95
Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis. Int J Epidemiol (2012) 0.95
Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. Am J Hum Genet (2008) 0.94
An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD. Am J Med Genet B Neuropsychiatr Genet (2007) 0.93
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol (2015) 0.93
Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men. PLoS Genet (2011) 0.92
Polymorphism in HSD17B6 is associated with key features of polycystic ovary syndrome. Fertil Steril (2006) 0.91
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes. Hum Genet (2003) 0.91
Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis. Bone (2009) 0.90
Utilising family-based designs for detecting rare variant disease associations. Ann Hum Genet (2014) 0.88
Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation. Neurobiol Aging (2012) 0.88
Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs. PLoS One (2013) 0.87
Early and current socio-economic position and cardiometabolic risk factors in the Indian Migration Study. Eur J Prev Cardiol (2012) 0.87
Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI. Hum Mol Genet (2012) 0.87
A general framework for two-stage analysis of genome-wide association studies and its application to case-control studies. Am J Hum Genet (2012) 0.87
Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores. Genet Epidemiol (2013) 0.85
Two novel pathway analysis methods based on a hierarchical model. Bioinformatics (2013) 0.84
Identification of variation in the platelet transcriptome associated with glycoprotein 6 haplotype. Platelets (2008) 0.84
Fast and robust association tests for untyped SNPs in case-control studies. Hum Hered (2010) 0.84
Evaluation of seven common lipid associated loci in a large Indian sib pair study. Lipids Health Dis (2012) 0.82
Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal. BMC Genet (2013) 0.80
Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro. J Bone Miner Res (2009) 0.80
Heritability of Individual Psychotic Experiences Captured by Common Genetic Variants in a Community Sample of Adolescents. Behav Genet (2015) 0.79
Accuracy of Gene Scores when Pruning Markers by Linkage Disequilibrium. Hum Hered (2016) 0.78
Transmission of human herpesvirus type 8 infection within families in american indigenous populations from the Brazilian Amazon. J Infect Dis (2012) 0.78
Erratum: Whole-genome sequence-based analysis of thyroid function. Nat Commun (2015) 0.77
Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome. Fertil Steril (2008) 0.76
Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations. Comput Biol Chem (2007) 0.76
Application of the optimal discovery procedure to genetic case-control studies: comparison with p values and asymptotic Bayes factors. Hum Hered (2011) 0.75
Commentary: Tobacco consumption and body weight: Mendelian randomization across a range of exposure. Int J Epidemiol (2015) 0.75