Published in Comput Biol Chem on March 24, 2007
A weighted average difference method for detecting differentially expressed genes from microarray data. Algorithms Mol Biol (2008) 1.27
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet (2010) 7.62
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet (2011) 6.36
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res (2006) 5.50
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet (2010) 5.31
Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation (2008) 5.20
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet (2008) 4.96
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet (2012) 4.46
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry (2011) 4.29
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet (2012) 4.13
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nat Genet (2012) 3.77
A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood (2009) 3.63
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet (2010) 3.34
Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet (2012) 3.31
Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data. BMC Genomics (2003) 3.30
An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet (2009) 3.05
Common variants near TERC are associated with mean telomere length. Nat Genet (2010) 2.98
IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology (2007) 2.97
Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays. Hum Mol Genet (2005) 2.56
Evaluation of Nyholt's procedure for multiple testing correction. Hum Hered (2005) 2.50
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood (2009) 2.25
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology (2008) 2.17
The use of edge-betweenness clustering to investigate biological function in protein interaction networks. BMC Bioinformatics (2005) 1.97
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet (2009) 1.97
On-chip single-copy real-time reverse-transcription PCR in isolated picoliter droplets. Anal Chem (2008) 1.96
Maximizing association statistics over genetic models. Genet Epidemiol (2008) 1.93
A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. Blood (2009) 1.85
Supra-domains: evolutionary units larger than single protein domains. J Mol Biol (2004) 1.82
Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome. Am J Hum Genet (2005) 1.78
Influence of 9p21.3 genetic variants on clinical and angiographic outcomes in early-onset myocardial infarction. J Am Coll Cardiol (2011) 1.73
Statistical analysis of domains in interacting protein pairs. Bioinformatics (2004) 1.64
A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood (2012) 1.59
Research review: Polygenic methods and their application to psychiatric traits. J Child Psychol Psychiatry (2014) 1.54
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
Copy number variation of the APC gene is associated with regulation of bone mineral density. Bone (2012) 1.46
Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins. Blood (2008) 1.45
Distinct cytokine-driven responses of activated blood gammadelta T cells: insights into unconventional T cell pleiotropy. J Immunol (2007) 1.42
Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet (2011) 1.41
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres. EMBO J (2007) 1.38
Adventitious changes in long-range gene expression caused by polymorphic structural variation and promoter competition. Proc Natl Acad Sci U S A (2009) 1.35
Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nat Genet (2011) 1.30
Highly Sensitive, Mechanically Stable Nanopore Sensors for DNA Analysis. Adv Mater (2009) 1.29
A note on permutation tests in multistage association scans. Am J Hum Genet (2006) 1.28
Cross-domain inhibition of TACE ectodomain. Proc Natl Acad Sci U S A (2011) 1.26
Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort. Eur J Hum Genet (2006) 1.25
Neonates harbour highly active gammadelta T cells with selective impairments in preterm infants. Eur J Immunol (2009) 1.23
Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemia myelodysplasia syndrome (ATMDS). Nat Genet (2003) 1.17
Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. Blood (2010) 1.16
First cleavage of the mouse embryo responds to change in egg shape at fertilization. Curr Biol (2004) 1.16
Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. Am J Psychiatry (2012) 1.15
Endothelial nitric oxide synthase polymorphisms are associated with type 2 diabetes and the insulin resistance syndrome. Diabetes (2003) 1.15
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet (2013) 1.15
Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution. PLoS One (2010) 1.09
Re: Is the Risk Difference Really a More Heterogeneous Measure? Epidemiology (2016) 1.08
Association between walking speed and age in healthy, free-living individuals using mobile accelerometry--a cross-sectional study. PLoS One (2011) 1.06
What role for genetics in the prediction of multiple sclerosis? Ann Neurol (2010) 1.05
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. Eur J Hum Genet (2009) 1.05
Genome-wide association study of multiplex schizophrenia pedigrees. Am J Psychiatry (2012) 1.05
Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis. BMC Med Genomics (2008) 1.04
Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population. Inflamm Bowel Dis (2008) 1.04
Klp10A, a microtubule-depolymerizing kinesin-13, cooperates with CP110 to control Drosophila centriole length. Curr Biol (2012) 1.03