Host genes important to HIV replication and evolution.

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Published in Cold Spring Harb Perspect Med on April 01, 2012

Authors

Amalio Telenti1, Welkin E Johnson

Author Affiliations

1: Institute of Microbiology, University Hospital and University of Lausanne, 1011 Lausanne, Switzerland. Amalio.Telenti@chuv.ch

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Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science (1995) 17.42

The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility. Science (2005) 17.00

Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science (1996) 15.63

A whole-genome association study of major determinants for host control of HIV-1. Science (2007) 15.19

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Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat Med (1996) 10.49

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Isolation of T-cell tropic HTLV-III-like retrovirus from macaques. Science (1985) 9.27

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Human immunodeficiency virus type 1, human protein interaction database at NCBI. Nucleic Acids Res (2008) 3.54

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Endogenous viral elements in animal genomes. PLoS Genet (2010) 2.97

Macrophage inflammatory protein-1. Cytokine Growth Factor Rev (2002) 2.93

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Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. Nat Immunol (2001) 2.52

A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3. J Virol (1997) 2.46

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