Published in PLoS Biol on February 09, 2010
TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species. PLoS Biol (2010) 3.21
Endogenous viral elements in animal genomes. PLoS Genet (2010) 2.97
Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses. Cell (2012) 2.94
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe (2012) 2.79
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Cell Host Microbe (2012) 2.66
Purifying selection can obscure the ancient age of viral lineages. Mol Biol Evol (2011) 2.43
Evolutionary conflicts between viruses and restriction factors shape immunity. Nat Rev Immunol (2012) 2.10
Filoviruses are ancient and integrated into mammalian genomes. BMC Evol Biol (2010) 1.87
Nutritional immunity. Escape from bacterial iron piracy through rapid evolution of transferrin. Science (2014) 1.74
Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses. J Virol (2010) 1.61
Genomic fossils calibrate the long-term evolution of hepadnaviruses. PLoS Biol (2010) 1.57
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Natural selection and infectious disease in human populations. Nat Rev Genet (2014) 1.48
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RNA-mediated interference and reverse transcription control the persistence of RNA viruses in the insect model Drosophila. Nat Immunol (2013) 1.24
Convergent evolution of escape from hepaciviral antagonism in primates. PLoS Biol (2012) 1.22
Paleozoic origin of insect large dsDNA viruses. Proc Natl Acad Sci U S A (2011) 1.20
Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses. PLoS Pathog (2013) 1.19
How SAMHD1 changes our view of viral restriction. Trends Immunol (2011) 1.15
When parasitic wasps hijacked viruses: genomic and functional evolution of polydnaviruses. Philos Trans R Soc Lond B Biol Sci (2013) 1.10
Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. PLoS Pathog (2013) 1.08
Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor. PLoS One (2012) 1.07
Short- and long-term evolutionary dynamics of bacterial insertion sequences: insights from Wolbachia endosymbionts. Genome Biol Evol (2011) 1.06
Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs. PLoS Pathog (2012) 1.05
The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection. J Virol (2011) 1.04
Evolutionary maintenance of filovirus-like genes in bat genomes. BMC Evol Biol (2011) 1.02
A cross-species view on viruses. Curr Opin Virol (2012) 1.01
APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription. J Virol (2013) 0.97
Host gene evolution traces the evolutionary history of ancient primate lentiviruses. Philos Trans R Soc Lond B Biol Sci (2013) 0.95
Host genes important to HIV replication and evolution. Cold Spring Harb Perspect Med (2012) 0.95
Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes. BMC Med (2012) 0.94
Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene. Hum Genet (2010) 0.93
Evolution of the antiretroviral restriction factor TRIMCyp in Old World primates. PLoS One (2010) 0.92
Species specificity of protein kinase r antagonism by cytomegalovirus TRS1 genes. J Virol (2012) 0.91
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Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections. J Virol (2013) 0.88
Unique spectrum of activity of prosimian TRIM5alpha against exogenous and endogenous retroviruses. J Virol (2011) 0.87
Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes. Proc Natl Acad Sci U S A (2013) 0.84
The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses. Retrovirology (2012) 0.83
Low frequency of paleoviral infiltration across the avian phylogeny. Genome Biol (2014) 0.83
Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus. Proc Natl Acad Sci U S A (2013) 0.83
The first full-length endogenous hepadnaviruses: identification and analysis. J Virol (2012) 0.83
Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors. Elife (2017) 0.83
Evolution of the retroviral restriction gene Fv1: inhibition of non-MLV retroviruses. PLoS Pathog (2014) 0.82
Species-specific transmission of novel picornaviruses in lemurs. J Virol (2015) 0.82
OASes and STING: adaptive evolution in concert. Genome Biol Evol (2015) 0.81
Extensive retroviral diversity in shark. Retrovirology (2015) 0.80
Plastic proteins and monkey blocks: how lentiviruses evolved to replicate in the presence of primate restriction factors. PLoS Pathog (2014) 0.79
Study of Sylvilagus rabbit TRIM5α species-specific domain: how ancient endoviruses could have shaped the antiviral repertoire in Lagomorpha. BMC Evol Biol (2011) 0.79
Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors. J Biol Chem (2015) 0.79
Apparent effect of rabbit endogenous lentivirus type K acquisition on retrovirus restriction by lagomorph Trim5αs. Philos Trans R Soc Lond B Biol Sci (2013) 0.78
Evolutionary and Functional Analysis of Old World Primate TRIM5 Reveals the Ancient Emergence of Primate Lentiviruses and Convergent Evolution Targeting a Conserved Capsid Interface. PLoS Pathog (2015) 0.77
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Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export. Retrovirology (2014) 0.76
The genomes of many yam species contain transcriptionally active endogenous geminiviral sequences that may be functionally expressed. Virus Evol (2015) 0.75
Identification and characterization of diverse groups of endogenous retroviruses in felids. Retrovirology (2015) 0.75
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Positive selection drives rapid evolution of certain amino acid residues in an evolutionarily highly conserved interferon-inducible antiviral protein of fishes. Immunogenetics (2012) 0.75
Presence of a Shared 5'-Leader Sequence in Ancestral Human and Mammalian Retroviruses and its Transduction into Feline Leukemia Virus. J Virol (2017) 0.75
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (2005) 17.19
Positive natural selection in the human lineage. Science (2006) 12.55
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature (2004) 7.10
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci U S A (2005) 6.85
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A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction. Curr Biol (2005) 5.24
Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction. J Virol (2005) 4.64
The origin, emergence and evolutionary genetics of dengue virus. Infect Genet Evol (2003) 3.83
The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates. J Virol (2005) 3.63
Genomewide screening reveals high levels of insertional polymorphism in the human endogenous retrovirus family HERV-K(HML2): implications for present-day activity. J Virol (2005) 3.26
Long-term reinfection of the human genome by endogenous retroviruses. Proc Natl Acad Sci U S A (2004) 3.19
Retroelement distributions in the human genome: variations associated with age and proximity to genes. Genome Res (2002) 3.14
Endogenous non-retroviral RNA virus elements in mammalian genomes. Nature (2010) 2.91
Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host Microbe (2008) 2.85
Ancient co-speciation of simian foamy viruses and primates. Nature (2005) 2.71
Identification of an infectious progenitor for the multiple-copy HERV-K human endogenous retroelements. Genome Res (2006) 2.55
Reconstitution of an infectious human endogenous retrovirus. PLoS Pathog (2007) 2.52
A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution. Proc Natl Acad Sci U S A (2008) 2.28
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Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature (2008) 2.13
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On the origin of smallpox: correlating variola phylogenics with historical smallpox records. Proc Natl Acad Sci U S A (2007) 1.84
Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biol (2005) 1.82
Reawakening retrocyclins: ancestral human defensins active against HIV-1. PLoS Biol (2009) 1.80
The evolutionary dynamics of human endogenous retroviral families. Annu Rev Genomics Hum Genet (2006) 1.79
Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science (2007) 1.76
Parallel germline infiltration of a lentivirus in two Malagasy lemurs. PLoS Genet (2009) 1.69
Integration target site selection by a resurrected human endogenous retrovirus. Genes Dev (2009) 1.62
Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. PLoS Genet (2008) 1.52
A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus. Virology (2008) 1.52
Dating the age of the SIV lineages that gave rise to HIV-1 and HIV-2. PLoS Comput Biol (2009) 1.47
Poxviruses as possible vectors for horizontal transfer of retroposons from reptiles to mammals. Proc Natl Acad Sci U S A (2007) 1.44
The evolutionary dynamics of endogenous retroviruses. Trends Microbiol (2005) 1.41
Evidence of the recombinant origin of a bat severe acute respiratory syndrome (SARS)-like coronavirus and its implications on the direct ancestor of SARS coronavirus. J Virol (2007) 1.39
Evolution of cyclophilin A and TRIMCyp retrotransposition in New World primates. J Virol (2005) 1.37
Poxvirus genome evolution by gene gain and loss. Mol Phylogenet Evol (2005) 1.34
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Evolution of human endogenous retroviral sequences: a conceptual account. Cell Mol Life Sci (2008) 1.26
Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha. PLoS Pathog (2007) 1.11
Multiple evolutionary mechanisms drive papillomavirus diversification. Mol Biol Evol (2007) 1.10
A novel gamma 2-herpesvirus of the Rhadinovirus 2 lineage in chimpanzees. Genome Res (2001) 1.07
Origins of human virus diversity. Cell (2002) 1.05
Adaptation and immunity. PLoS Biol (2004) 1.01
Evidence for restriction of ancient primate gammaretroviruses by APOBEC3 but not TRIM5alpha proteins. PLoS Pathog (2008) 0.99
Antiretroviral activity of ancestral TRIM5alpha. J Virol (2007) 0.97
Phylogenetic analysis, genome evolution and the rate of gene gain in the Herpesviridae. Mol Phylogenet Evol (2006) 0.88
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci U S A (2005) 6.85
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. PLoS Biol (2004) 4.76
Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. PLoS Genet (2009) 3.60
Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses. Cell (2012) 2.94
Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host Microbe (2008) 2.85
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe (2012) 2.79
Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. J Virol (2006) 2.40
The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions. Genome Res (2009) 2.35
Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9. RNA (2003) 2.23
Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature (2008) 2.13
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The evolutionary conundrum of pathogen mimicry. Nat Rev Microbiol (2009) 1.87
Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol (2008) 1.86
High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Curr Biol (2006) 1.85
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science (2007) 1.76
Centromeres: selfish drivers. Nature (2002) 1.63
Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses. J Virol (2010) 1.61
Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PLoS Pathog (2007) 1.60
Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species. Science (2009) 1.58
Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila. PLoS Genet (2005) 1.57
Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. PLoS Genet (2008) 1.52
Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J Exp Med (2012) 1.48
Multiple roles for heterochromatin protein 1 genes in Drosophila. Annu Rev Genet (2009) 1.41
Paleovirology - ghosts and gifts of viruses past. Curr Opin Virol (2011) 1.37
Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA. Cell Host Microbe (2012) 1.29
Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis. Proc Natl Acad Sci U S A (2006) 1.26
Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes. Proc Natl Acad Sci U S A (2013) 1.24
Convergent evolution of escape from hepaciviral antagonism in primates. PLoS Biol (2012) 1.22
Ancient lineages of non-LTR retrotransposons in the primitive eukaryote, Giardia lamblia. Mol Biol Evol (2002) 1.21
Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila. Proc Natl Acad Sci U S A (2007) 1.14
Stepwise evolution of essential centromere function in a Drosophila neogene. Science (2013) 1.13
An expanded clade of rodent Trim5 genes. Virology (2009) 1.10
The CNA1 histone of the ciliate Tetrahymena thermophila is essential for chromosome segregation in the germline micronucleus. Mol Biol Cell (2005) 1.05
The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection. J Virol (2011) 1.04
An evolutionary perspective on the broad antiviral specificity of MxA. Curr Opin Microbiol (2013) 1.02
Host gene evolution traces the evolutionary history of ancient primate lentiviruses. Philos Trans R Soc Lond B Biol Sci (2013) 0.95
Phylogenomic analysis reveals dynamic evolutionary history of the Drosophila heterochromatin protein 1 (HP1) gene family. PLoS Genet (2012) 0.91
Birth, death, and replacement of karyopherins in Drosophila. Mol Biol Evol (2011) 0.84
The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses. Retrovirology (2012) 0.83
Absence of positive selection on centromeric histones in Tetrahymena suggests unsuppressed centromere: drive in lineages lacking male meiosis. J Mol Evol (2011) 0.83
A rapidly evolving genomic toolkit for Drosophila heterochromatin. Fly (Austin) (2013) 0.79
An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family. Genome Biol Evol (2013) 0.79
A surrogate approach to study the evolution of noncoding DNA elements that organize eukaryotic genomes. J Hered (2009) 0.79
Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces. BMC Evol Biol (2010) 0.77
Learning to protect your genome on the fly. Cell (2011) 0.76
Molecular evolution of Drosophila Cdc6, an essential DNA replication-licensing gene, suggests an adaptive choice of replication origins. Fly (Austin) (2008) 0.76
Diamonds and rust: how transposable elements influence mammalian genomes. Conference on Mobile Elements in Mammalian Genomes. EMBO Rep (2009) 0.75
Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev (2017) 0.75