Published in Nucleic Acids Res on April 05, 2012
Transposable elements reveal a stem cell-specific class of long noncoding RNAs. Genome Biol (2012) 2.22
Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep (2012) 1.82
Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma. J Cancer Res Clin Oncol (2012) 1.66
Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy. PLoS One (2013) 1.58
Expression of Hox genes during regeneration of nereid polychaete Alitta (Nereis) virens (Annelida, Lophotrochozoa). Evodevo (2013) 1.44
Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation. PLoS One (2015) 1.40
Overexpression of long non-coding RNA UCA1 predicts a poor prognosis in patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol (2014) 1.39
The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells. Oncotarget (2014) 1.26
Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3. Oncotarget (2016) 1.20
Potential roles of microRNAs in regulating long intergenic noncoding RNAs. BMC Med Genomics (2013) 1.19
Characterization of a novel long noncoding RNA, SCAL1, induced by cigarette smoke and elevated in lung cancer cell lines. Am J Respir Cell Mol Biol (2013) 1.16
Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing. PLoS Comput Biol (2014) 1.15
Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells. PLoS Pathog (2013) 1.12
Comprehensive analysis of lncRNA expression profiles reveals a novel lncRNA signature to discriminate nonequivalent outcomes in patients with ovarian cancer. Oncotarget (2016) 1.11
Functions of microRNAs in cardiovascular biology and disease. Annu Rev Physiol (2012) 1.10
Cell cycle regulation by long non-coding RNAs. Cell Mol Life Sci (2013) 1.10
Regulation of viral and cellular gene expression by Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA. J Virol (2013) 1.09
Colon Cancer Associated Transcript-1 (CCAT1) Expression in Adenocarcinoma of the Stomach. J Cancer (2015) 1.07
The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population. Oncotarget (2015) 1.07
HELLP babies link a novel lincRNA to the trophoblast cell cycle. J Clin Invest (2012) 1.07
Long noncoding RNAs-related diseases, cancers, and drugs. ScientificWorldJournal (2013) 1.07
Long noncoding RNAs: new players in the molecular mechanism for maintenance and differentiation of pluripotent stem cells. Stem Cells Dev (2013) 1.07
Negative regulation of the interferon response by an interferon-induced long non-coding RNA. Nucleic Acids Res (2014) 1.02
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Functional transcriptomics in the post-ENCODE era. Genome Res (2013) 0.98
From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease. Endocr Rev (2014) 0.98
CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA. Mol Cancer (2015) 0.97
A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer. Oncotarget (2015) 0.97
Association of genetic variants in lncRNA H19 with risk of colorectal cancer in a Chinese population. Oncotarget (2016) 0.96
Long noncoding RNAs promote transcriptional poising of inducible genes. PLoS Biol (2013) 0.96
Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity. Sci Rep (2015) 0.95
Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. Biochem Pharmacol (2013) 0.95
A potential panel of six-long non-coding RNA signature to improve survival prediction of diffuse large-B-cell lymphoma. Sci Rep (2016) 0.94
Long non-coding RNAs in colorectal cancer. Oncotarget (2016) 0.92
Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer. Genomics Proteomics Bioinformatics (2016) 0.91
Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and function. Neuroscience (2013) 0.89
Non-coding RNAs in the development of sensory organs and related diseases. Cell Mol Life Sci (2013) 0.88
Long non-coding RNAs and hepatocellular carcinoma. Mol Clin Oncol (2014) 0.87
The functions of microRNAs and long non-coding RNAs in embryonic and induced pluripotent stem cells. Genomics Proteomics Bioinformatics (2013) 0.87
Influence of RNA extraction methods and library selection schemes on RNA-seq data. BMC Genomics (2014) 0.87
The DMD locus harbours multiple long non-coding RNAs which orchestrate and control transcription of muscle dystrophin mRNA isoforms. PLoS One (2012) 0.87
Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases. Int J Mol Sci (2015) 0.87
Genome-wide analysis of long noncoding RNA (lncRNA) expression in colorectal cancer tissues from patients with liver metastasis. Cancer Med (2016) 0.86
Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex (2014) 0.85
Evolutionarily conserved long intergenic non-coding RNAs in the eye. Hum Mol Genet (2013) 0.85
AB209630, a long non-coding RNA decreased expression in hypopharyngeal squamous cell carcinoma, influences proliferation, invasion, metastasis, and survival. Oncotarget (2016) 0.85
Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion Syndrome. G3 (Bethesda) (2015) 0.85
Genome-wide identification and functional analysis of lincRNAs acting as miRNA targets or decoys in maize. BMC Genomics (2015) 0.85
Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of systemic sclerosis and Sjögren's syndrome. Autoimmun Rev (2013) 0.84
Computational prediction of polycomb-associated long non-coding RNAs. PLoS One (2012) 0.84
RNA regulators of host immunity and pathogen adaptive responses in the oral cavity. Microbes Infect (2015) 0.84
KDM1 class flavin-dependent protein lysine demethylases. Biopolymers (2015) 0.84
Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome. BMC Genomics (2012) 0.84
Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts. RNA Biol (2014) 0.83
Imprinted and X-linked non-coding RNAs as potential regulators of human placental function. Epigenetics (2013) 0.82
A novel molecular mechanism in human genetic disease: a DNA repeat-derived lncRNA. RNA Biol (2012) 0.82
LincRNA-p21: Implications in Human Diseases. Int J Mol Sci (2015) 0.81
The Emerging Functions of Long Noncoding RNA in Immune Cells: Autoimmune Diseases. J Immunol Res (2015) 0.81
Expression profiling of RNA transcripts during neuronal maturation and ischemic injury. PLoS One (2014) 0.81
Long Non-Coding RNAs in Infection Biology. Front Genet (2013) 0.81
Short stories on zebrafish long noncoding RNAs. Zebrafish (2014) 0.81
Genome-wide analysis of long non-coding RNAs at early stage of skin pigmentation in goats (Capra hircus). BMC Genomics (2016) 0.81
Role of Pnn in alternative splicing of a specific subset of lncRNAs of the corneal epithelium. Mol Vis (2014) 0.80
Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma. Oncotarget (2016) 0.80
Microarray analysis of long noncoding RNA and mRNA expression profiles in human macrophages infected with Mycobacterium tuberculosis. Sci Rep (2016) 0.80
Identification of non-coding RNAs with a new composite feature in the Hybrid Random Forest Ensemble algorithm. Nucleic Acids Res (2014) 0.80
Regulation of the mRNA half-life in breast cancer. World J Clin Oncol (2014) 0.80
Microarray analysis of Long non-coding RNA expression profiles in human gastric cells and tissues with Helicobacter pylori Infection. BMC Med Genomics (2015) 0.80
Sequencing and characterization of striped venus transcriptome expand resources for clam fishery genetics. PLoS One (2012) 0.80
Long Non-coding RNAs in the Cytoplasm. Genomics Proteomics Bioinformatics (2016) 0.79
Long non-coding RNA derived miR-205-5p modulates human endometrial cancer by targeting PTEN. Am J Transl Res (2015) 0.79
Downregulation of long noncoding RNA MEG3 is associated with poor prognosis and promoter hypermethylation in cervical cancer. J Exp Clin Cancer Res (2017) 0.79
Non-coding RNAs in DNA damage response. Am J Cancer Res (2012) 0.79
Comparison of long non‑coding RNAs, microRNAs and messenger RNAs involved in initiation and progression of esophageal squamous cell carcinoma. Mol Med Rep (2014) 0.79
Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder. Transl Psychiatry (2015) 0.79
LincRNA-Cox2 Promotes Late Inflammatory Gene Transcription in Macrophages through Modulating SWI/SNF-Mediated Chromatin Remodeling. J Immunol (2016) 0.79
Analysis of the transcriptome in molecular epidemiology studies. Environ Mol Mutagen (2013) 0.79
Long interspersed nuclear elements (LINEs) show tissue-specific, mosaic genome and methylation-unrestricted, widespread expression of noncoding RNAs in somatic tissues of the rat. RNA Biol (2012) 0.78
Exploratory bioinformatics study of lncRNAs in Alzheimer's disease mRNA sequences with application to drug development. Comput Math Methods Med (2013) 0.78
LncRNA DQ786243 contributes to proliferation and metastasis of colorectal cancer both in vitro and in vivo. Biosci Rep (2016) 0.78
Big (sequencing) future of non-coding RNA research for the understanding of cocaine. Front Genet (2012) 0.78
RNA-binding proteins in pluripotency, differentiation, and reprogramming. Front Biol (Beijing) (2014) 0.78
The function of homeobox genes and lncRNAs in cancer. Oncol Lett (2016) 0.78
Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells. Mol Cell Proteomics (2015) 0.78
Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System. J Immunol (2016) 0.78
Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer. PLoS One (2017) 0.78
A comprehensive view of the epigenetic landscape. Part II: Histone post-translational modification, nucleosome level, and chromatin regulation by ncRNAs. Neurotox Res (2014) 0.77
There is a world beyond protein mutations: the role of non-coding RNAs in melanomagenesis. Exp Dermatol (2013) 0.77
Non-Coding RNAs as Potential Neuroprotectants against Ischemic Brain Injury. Brain Sci (2013) 0.77
Associating schizophrenia, long non-coding RNAs and neurostructural dynamics. Front Mol Neurosci (2015) 0.77
Long Noncoding RNA-Sox2OT Knockdown Alleviates Diabetes Mellitus-Induced Retinal Ganglion Cell (RGC) injury. Cell Mol Neurobiol (2016) 0.77
Long noncoding RNAs (lncRNAs) dynamics evidence immunomodulation during ISAV-Infected Atlantic salmon (Salmo salar). Sci Rep (2016) 0.77
Identification and characterization of long intergenic non-coding RNAs related to mouse liver development. Mol Genet Genomics (2014) 0.77
Histone Deacetylase Inhibitors as Anticancer Drugs. Int J Mol Sci (2017) 0.77
Critical roles of long noncoding RNAs in Drosophila spermatogenesis. Genome Res (2016) 0.76
Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer. Oncotarget (2016) 0.76
Long noncoding RNA MALAT1 as a putative biomarker of lymph node metastasis: a meta-analysis. Int J Clin Exp Med (2015) 0.76
Comprehensive analysis of lncRNA expression profiles and identification of functional lncRNAs in lung adenocarcinoma. Oncotarget (2016) 0.76
Differential transcription profiles of long non-coding RNAs in primary human brain microvascular endothelial cells in response to meningitic Escherichia coli. Sci Rep (2016) 0.76
Combining DGE and RNA-sequencing data to identify new polyA+ non-coding transcripts in the human genome. Nucleic Acids Res (2013) 0.76
High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18
Chromatin modifications and their function. Cell (2007) 55.98
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature (2009) 35.48
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet (2006) 20.76
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci U S A (2009) 20.66
Long non-coding RNAs: insights into functions. Nat Rev Genet (2009) 19.61
Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs. Nat Biotechnol (2010) 18.44
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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev (2011) 16.77
Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
Long noncoding RNA as modular scaffold of histone modification complexes. Science (2010) 15.23
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Long noncoding RNAs with enhancer-like function in human cells. Cell (2010) 13.00
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature (2005) 12.06
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature (2011) 11.59
Molecular mechanisms of long noncoding RNAs. Mol Cell (2011) 11.44
lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature (2011) 11.31
Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell (2011) 10.56
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell (2008) 9.76
Target mimicry provides a new mechanism for regulation of microRNA activity. Nat Genet (2007) 9.48
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell (2010) 8.66
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science (2008) 8.45
Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22. Genome Res (2004) 8.35
A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature (1991) 8.22
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell (1992) 8.05
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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature (2008) 7.64
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Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell (2010) 6.88
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol Cell (2011) 6.83
The transcriptional activity of human Chromosome 22. Genes Dev (2003) 6.82
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The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell (1992) 6.26
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell (2009) 6.08
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res (2011) 6.02
Genome-wide measurement of RNA secondary structure in yeast. Nature (2010) 5.74
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell (2011) 5.65
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet (2011) 5.62
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
The product of the H19 gene may function as an RNA. Mol Cell Biol (1990) 5.61
Regulating gene expression through RNA nuclear retention. Cell (2005) 5.58
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell (2007) 5.40
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet (2010) 5.37
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MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res (2008) 5.06
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Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci Signal (2010) 4.77
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ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell (2011) 4.26
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Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation. Cell (2001) 4.21
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Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann Surg Oncol (2011) 3.88
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Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation. Med Oncol (2011) 3.24
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Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology (2011) 3.05
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The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Res (2011) 2.52
Regulation of X-chromosome inactivation by the X-inactivation centre. Nat Rev Genet (2011) 2.50
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RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet (2009) 2.45
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Structural and functional differences in the long non-coding RNA hotair in mouse and human. PLoS Genet (2011) 2.20
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Decapping of long noncoding RNAs regulates inducible genes. Mol Cell (2012) 1.57
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One (2008) 1.57
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The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia. Best Pract Res Clin Haematol (2007) 1.34
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Xist regulation and function explored. Hum Genet (2011) 1.28
Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS. J Biol Chem (2005) 1.24
ncRAN, a newly identified long noncoding RNA, enhances human bladder tumor growth, invasion, and survival. Urology (2010) 1.18
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
MicroRNA-143 regulates adipocyte differentiation. J Biol Chem (2004) 6.78
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs. Nucleic Acids Res (2004) 3.11
The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Res (2011) 2.52
MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells (2007) 2.40
An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis. J Lipid Res (2005) 1.96
A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol (2008) 1.80
Decapping of long noncoding RNAs regulates inducible genes. Mol Cell (2012) 1.57
The regulation of miRNA-211 expression and its role in melanoma cell invasiveness. PLoS One (2010) 1.55
Nucleosome occupancy landscape and dynamics at mouse recombination hotspots. EMBO Rep (2010) 1.22
Emerging Roles for Long Non-Coding RNAs in Cancer and Neurological Disorders. Front Genet (2012) 1.13
Epigenetic regulation of microRNA-375 and its role in melanoma development in humans. FEBS Lett (2011) 1.00
Epigenetic regulation of microRNA genes and the role of miR-34b in cell invasion and motility in human melanoma. PLoS One (2011) 0.94
Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network. Sci Rep (2013) 0.87
Protein-coding and non-coding gene expression analysis in differentiating human keratinocytes using a three-dimensional epidermal equivalent. Mol Genet Genomics (2010) 0.87
Long noncoding RNAs as putative biomarkers for prostate cancer detection. J Mol Diagn (2014) 0.87
Identification of a novel lncRNA in gluteal adipose tissue and evidence for its positive effect on preadipocyte differentiation. Obesity (Silver Spring) (2014) 0.86
Evolutionarily conserved long intergenic non-coding RNAs in the eye. Hum Mol Genet (2013) 0.85
Evaluation of selected biochemical parameters in the saliva of young males using mobile phones. Electromagn Biol Med (2014) 0.84
Co-Immunoprecipitation of long noncoding RNAs. Methods Mol Biol (2012) 0.84
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer. Breast Cancer Res Treat (2015) 0.78
Diverse functions and mechanisms of mammalian long noncoding RNAs. Methods Mol Biol (2015) 0.76
In vitro cytogenetic testing of an organoselenium compound and its sulfur analogue in cultured rat bone marrow cells. J Carcinog (2004) 0.75