Published in PLoS Comput Biol on April 12, 2012
N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods. J Cell Biol (2012) 1.45
Exosome secretion is enhanced by invadopodia and drives invasive behavior. Cell Rep (2013) 1.26
Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis. Sci Signal (2012) 1.19
Critical role of transient activity of MT1-MMP for ECM degradation in invadopodia. PLoS Comput Biol (2013) 1.07
A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination. J Cell Biol (2014) 1.04
Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis. J Exp Clin Cancer Res (2015) 0.91
ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo. J Cell Biol (2014) 0.90
Mathematical modeling of cancer invasion: the role of membrane-bound matrix metalloproteinases. Front Oncol (2013) 0.89
Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP. Mol Cell Biol (2013) 0.87
Spatial chaos and complexity in the intracellular space of cancer and normal cells. Theor Biol Med Model (2013) 0.86
Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network. PLoS Comput Biol (2015) 0.81
The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation. Front Oncol (2013) 0.78
Dynamic regulation of a cell adhesion protein complex including CADM1 by combinatorial analysis of FRAP with exponential curve-fitting. PLoS One (2015) 0.77
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep (2016) 0.77
The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia. PLoS One (2013) 0.77
Raf kinase inhibitor protein (RKIP) inhibits the cell migration and invasion in human glioma cell lines in vitro. Int J Clin Exp Pathol (2015) 0.76
A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation. PLoS Genet (2016) 0.76
Modeling extracellular matrix reorganization in 3D environments. PLoS One (2013) 0.76
Finding Solvable Units of Variables in Nonlinear ODEs of ECM Degradation Pathway Network. Comput Math Methods Med (2017) 0.75
Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype. Sci Rep (2017) 0.75
Spatial uncertainty modeling of fuzzy information in images for pattern classification. PLoS One (2014) 0.75
RABGTPases in MT1-MMP trafficking and cell invasion: Physiology versus pathology. Small GTPases (2015) 0.75
Control and inhibition analysis of complex formation processes. Theor Biol Med Model (2012) 0.75
Free boundary problem for cell protrusion formations: theoretical and numerical aspects. J Math Biol (2016) 0.75
Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta (2006) 4.27
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res (2006) 3.83
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res (2007) 3.30
Assembly and biological role of podosomes and invadopodia. Curr Opin Cell Biol (2008) 3.26
Invadopodia: specialized cell structures for cancer invasion. Clin Exp Metastasis (2006) 3.05
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. J Cell Sci (2009) 2.94
Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport. Nat Cell Biol (2005) 2.50
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A (1997) 2.35
Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system. J Cell Biol (1988) 2.31
Dynamin participates in focal extracellular matrix degradation by invasive cells. Mol Biol Cell (2003) 2.19
MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway. EMBO J (2007) 2.16
Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases. FEBS Lett (2001) 2.15
Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization. J Biol Chem (1990) 2.02
The cofilin activity cycle in lamellipodia and invadopodia. J Cell Biochem (2009) 1.99
Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin Exp Metastasis (2008) 1.83
Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis. Proc Natl Acad Sci U S A (2001) 1.83
Invadopodia and podosomes in tumor invasion. Eur J Cell Biol (2005) 1.75
Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity. J Cell Biol (2001) 1.71
Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface. J Cell Sci (2003) 1.68
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7. Curr Biol (2008) 1.55
A theoretical model of type I collagen proteolysis by matrix metalloproteinase (MMP) 2 and membrane type 1 MMP in the presence of tissue inhibitor of metalloproteinase 2. J Biol Chem (2004) 1.51
Lipid rafts and caveolin-1 are required for invadopodia formation and extracellular matrix degradation by human breast cancer cells. Cancer Res (2009) 1.42
Caveolae are a novel pathway for membrane-type 1 matrix metalloproteinase traffic in human endothelial cells. Mol Biol Cell (2003) 1.39
Actin dynamics at sites of extracellular matrix degradation. Eur J Cell Biol (2006) 1.36
Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP. Mol Biol Cell (2006) 1.26
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice. Cancer Res (2007) 1.21
Mathematical modelling of cancer cell invasion of tissue: local and non-local models and the effect of adhesion. J Theor Biol (2008) 1.16
A novel protein associated with membrane-type 1 matrix metalloproteinase binds p27(kip1) and regulates RhoA activation, actin remodeling, and matrigel invasion. J Biol Chem (2009) 1.13
Type I collagen abrogates the clathrin-mediated internalization of membrane type 1 matrix metalloproteinase (MT1-MMP) via the MT1-MMP hemopexin domain. J Biol Chem (2005) 1.01
Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation. J Math Biol (2010) 1.00
MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis. Oncogene (2011) 0.98
Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo. Mol Cancer Ther (2005) 0.97
A-Cell: graphical user interface for the construction of biochemical reaction models. Bioinformatics (2001) 0.93
The impact of adhesion on cellular invasion processes in cancer and development. J Theor Biol (2010) 0.92
A modeling environment with three-dimensional morphology, A-Cell-3D, and Ca2+ dynamics in a spine. Neuroinformatics (2005) 0.90
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature (2006) 7.56
Avian flu: isolation of drug-resistant H5N1 virus. Nature (2005) 6.66
Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature (2004) 6.11
Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell (2006) 4.07
A simplified laminin nomenclature. Matrix Biol (2005) 3.81
A two-step method for marking polypectomy sites in the colon and rectum. Gastrointest Endosc (2003) 3.63
MT1-MMP: a potent modifier of pericellular microenvironment. J Cell Physiol (2006) 3.37
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res (2007) 3.30
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol (2005) 3.02
Cortactin promotes cell motility by enhancing lamellipodial persistence. Curr Biol (2005) 2.78
Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov (2008) 2.58
Heterogeneous increase in CD34-positive alveolar capillaries in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2004) 2.35
Integrative mathematical oncology. Nat Rev Cancer (2008) 2.28
Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury. J Immunol (2004) 2.25
Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol (2003) 2.12
Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors. J Neurochem (2011) 2.11
Long-tube insertion with the ropeway method facilitated by a guidewire placed by transnasal ultrathin endoscopy for bowel obstruction: a prospective, randomized, controlled trial. Gastrointest Endosc (2009) 2.10
Characterization of a human H5N1 influenza A virus isolated in 2003. J Virol (2005) 2.09
Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts. J Cell Sci (2004) 2.08
CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain. EMBO J (2002) 2.05
N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses. J Biol Chem (2008) 2.05
Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma--an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy. Expert Opin Ther Targets (2012) 2.00
Variable lymphocyte receptors in hagfish. Proc Natl Acad Sci U S A (2005) 1.99
MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis. Dev Cell (2013) 1.95
Low blood pressure in endothelial cell-specific endothelin 1 knockout mice. Hypertension (2010) 1.91
Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5. Sci Signal (2011) 1.88
Changes in microRNA expression levels correlate with clinicopathological features and prognoses in endometrial serous adenocarcinomas. Cancer Sci (2009) 1.85
Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1. J Biol Chem (2002) 1.81
Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema. FEBS Lett (2004) 1.77
The human CYP19 (aromatase P450) gene: update on physiologic roles and genomic organization of promoters. J Steroid Biochem Mol Biol (2003) 1.77
Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers. Oncogene (2002) 1.75
Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition. Circulation (2010) 1.72
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion. Curr Biol (2003) 1.72
Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. J Cell Biol (2004) 1.72
Influenza A (H5N1) viruses from pigs, Indonesia. Emerg Infect Dis (2010) 1.70
Localization of aldosterone-producing adrenocortical adenomas: significance of adrenal venous sampling. Hypertens Res (2007) 1.68
Expression of urocortin and corticotropin-releasing factor receptor subtypes in the human heart. J Clin Endocrinol Metab (2002) 1.66
Clinicopathological characteristics of breast cancer and trends in the management of breast cancer patients in Japan: Based on the Breast Cancer Registry of the Japanese Breast Cancer Society between 2004 and 2011. Breast Cancer (2015) 1.64
Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells. J Cell Sci (2007) 1.57
Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma. Cancer Sci (2012) 1.54
Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton. Cancer Res (2009) 1.53
A new role for cortactin in invadopodia: regulation of protease secretion. Eur J Cell Biol (2008) 1.52
Dissecting human adrenal androgen production. Trends Endocrinol Metab (2002) 1.52
Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors. Oncogene (2003) 1.52
Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development. Development (2006) 1.52
Progesterone receptor in non-small cell lung cancer--a potent prognostic factor and possible target for endocrine therapy. Cancer Res (2005) 1.51
Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. J Biol Chem (2006) 1.49
CAS promotes invasiveness of Src-transformed cells. Oncogene (2004) 1.49
Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. EMBO J (2013) 1.48
Plasma total homocysteine and gallstone in middle-aged Japanese men. J Gastroenterol (2005) 1.46
Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment. Gut (2011) 1.46
Mathematical modeling of cancer: the future of prognosis and treatment. Clin Chim Acta (2005) 1.43
Sex steroid hormone receptors in human thymoma. J Clin Endocrinol Metab (2003) 1.38
Tales from the crypt[ic] sites of the extracellular matrix. Trends Cell Biol (2003) 1.37
The quail and chicken intestine have sialyl-galactose sugar chains responsible for the binding of influenza A viruses to human type receptors. Glycobiology (2007) 1.37
Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. ACS Chem Biol (2009) 1.37
In situ androgen producing enzymes in human prostate cancer. Endocr Relat Cancer (2005) 1.37
Expression and sub-cellular localization of human ABH family molecules. J Cell Mol Med (2007) 1.36
Cortactin: a multifunctional regulator of cellular invasiveness. Cell Adh Migr (2011) 1.36
Incidence and burden of rotavirus gastroenteritis in Japan, as estimated from a prospective sentinel hospital study. J Infect Dis (2005) 1.36
IL-28 elicits antitumor responses against murine fibrosarcoma. J Immunol (2007) 1.35
Microenvironment driven invasion: a multiscale multimodel investigation. J Math Biol (2008) 1.34
Intratumoral estrogens and estrogen receptors in human non-small cell lung carcinoma. Clin Cancer Res (2008) 1.33
Normalizing DNA microarray data. Curr Issues Mol Biol (2002) 1.33
Multifunctional roles of MT1-MMP in myofiber formation and morphostatic maintenance of skeletal muscle. J Cell Sci (2006) 1.32
Membrane type 1 matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-related kinase activation and cell migration. Cancer Res (2004) 1.27
Materials chemistry: a synthetic enamel for rapid tooth repair. Nature (2005) 1.27
IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness. Cancer Res (2004) 1.27
The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. implications for the control of adrenal functional zonation. J Biol Chem (2004) 1.27
Role of sulfatide in normal and pathological cells and tissues. J Lipid Res (2012) 1.27
Impact of a transparent hood on the performance of total colonoscopy: a randomized controlled trial. Gastrointest Endosc (2009) 1.26
Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP. Mol Biol Cell (2006) 1.26
Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res (2006) 1.26
Oligosaccharides as receptors for JC virus. J Virol (2002) 1.25
Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. J Ethnopharmacol (2006) 1.25
Chemoenzymatic synthesis and application of glycopolymers containing multivalent sialyloligosaccharides with a poly(L-glutamic acid) backbone for inhibition of infection by influenza viruses. Glycobiology (2002) 1.24
Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools. PLoS One (2009) 1.24
Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells. J Biol Chem (2006) 1.23
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (2013) 1.23
Adhesion rings surround invadopodia and promote maturation. Biol Open (2012) 1.23
Proteolytic processing of laminin-5 by MT1-MMP in tissues and its effects on epithelial cell morphology. FASEB J (2003) 1.23
Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. Biochem Biophys Res Commun (2003) 1.23
Human trachea primary epithelial cells express both sialyl(alpha2-3)Gal receptor for human parainfluenza virus type 1 and avian influenza viruses, and sialyl(alpha2-6)Gal receptor for human influenza viruses. Glycoconj J (2006) 1.22
Turnover of focal adhesions and cancer cell migration. Int J Cell Biol (2012) 1.22
A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro. BMC Cancer (2008) 1.21
The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production. Mol Endocrinol (2003) 1.21
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice. Cancer Res (2007) 1.21
Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain. J Biol Chem (2004) 1.21
Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth. Cancer Res (2009) 1.20
Systemic distribution of somatostatin receptor subtypes in human: an immunohistochemical study. Endocr J (2005) 1.19
Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis. Sci Signal (2012) 1.19