Published in Proc Natl Acad Sci U S A on November 06, 2001
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39
Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev (2012) 2.22
MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway. EMBO J (2007) 2.16
Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia (2004) 1.70
High-affinity peptide against MT1-MMP for in vivo tumor imaging. J Control Release (2011) 1.59
Matrix metalloproteinases: old dogs with new tricks. Genome Biol (2003) 1.59
ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells. J Cell Biol (2002) 1.48
An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature. Genes Dev (2005) 1.47
N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods. J Cell Biol (2012) 1.45
Caveolae are a novel pathway for membrane-type 1 matrix metalloproteinase traffic in human endothelial cells. Mol Biol Cell (2003) 1.39
Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation. J Anat (2002) 1.37
Matrix metalloproteases in head and neck cancer. Head Neck (2006) 1.35
MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer. Cancer Metastasis Rev (2008) 1.34
Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies. PLoS Comput Biol (2012) 1.33
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J Cell Biol (2013) 1.28
Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP. Mol Biol Cell (2006) 1.26
Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy. Biochim Biophys Acta (2009) 1.23
Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging. J Biol Chem (2008) 1.18
A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis. Mol Biol Cell (2006) 1.18
The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs. Am J Pathol (2009) 1.17
Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer. Cancer Res (2008) 1.14
The regulation of MMP targeting to invadopodia during cancer metastasis. Front Cell Dev Biol (2015) 1.11
Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination. Cancer Res (2009) 1.10
Molecular and cellular mechanisms of ectodomain shedding. Anat Rec (Hoboken) (2010) 1.08
Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices. J Biol Chem (2009) 1.08
Metalloendoprotease cleavage triggers gelsolin amyloidogenesis. EMBO J (2005) 1.00
The second dimer interface of MT1-MMP, the transmembrane domain, is essential for ProMMP-2 activation on the cell surface. J Biol Chem (2008) 0.99
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells. Clin Exp Metastasis (2003) 0.98
Membrane-bound and exosomal metastasis-associated C4.4A promotes migration by associating with the α(6)β(4) integrin and MT1-MMP. Neoplasia (2012) 0.97
Regulation of invadopodia formation and activity by CD147. J Cell Sci (2012) 0.95
FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex. Proc Natl Acad Sci U S A (2010) 0.94
Roles of matrix metalloproteinases and their natural inhibitors in prostate cancer progression. Cancers (Basel) (2014) 0.92
Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton. Mol Biol Cell (2014) 0.91
Nanopreparations for organelle-specific delivery in cancer. Adv Drug Deliv Rev (2013) 0.90
Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes. J Biol Chem (2010) 0.90
Epidermal growth factor receptor-mediated membrane type 1 matrix metalloproteinase endocytosis regulates the transition between invasive versus expansive growth of ovarian carcinoma cells in three-dimensional collagen. Mol Cancer Res (2009) 0.89
VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration. J Cell Sci (2012) 0.89
Inhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin-resistant rats. Br J Pharmacol (2012) 0.89
The cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase. J Biol Chem (2008) 0.88
LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP. Sci Rep (2016) 0.88
MT-LOOP-dependent localization of membrane type I matrix metalloproteinase (MT1-MMP) to the cell adhesion complexes promotes cancer cell invasion. J Biol Chem (2013) 0.87
Regulation of MT1-MMP activity by β-catenin in MDCK non-cancer and HT1080 cancer cells. J Cell Physiol (2010) 0.87
Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen. J Biol Chem (2012) 0.87
Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase. Biochem J (2005) 0.87
Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes. Vitam Horm (2009) 0.85
Mechanism of metastasis by membrane type 1-matrix metalloproteinase in hepatocellular carcinoma. World J Gastroenterol (2005) 0.84
Regulation of membrane-type 1 matrix metalloproteinase activity by vacuolar H+-ATPases. Biochem J (2003) 0.83
Quantitative FRET imaging to visualize the invasiveness of live breast cancer cells. PLoS One (2013) 0.82
BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity. J Cell Biochem (2012) 0.81
Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking. Biochem J (2007) 0.81
Dynamic interdomain interactions contribute to the inhibition of matrix metalloproteinases by tissue inhibitors of metalloproteinases. J Biol Chem (2011) 0.81
Peptide aptamers as new tools to modulate clathrin-mediated internalisation--inhibition of MT1-MMP internalisation. BMC Cell Biol (2010) 0.81
Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin. BMC Cell Biol (2011) 0.80
Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration. Cornea (2010) 0.80
Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells. J Cell Sci (2016) 0.80
The planar cell polarity protein VANGL2 coordinates remodeling of the extracellular matrix. Commun Integr Biol (2012) 0.78
Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process. Oncogene (2015) 0.78
Posttranslation modification of G protein-coupled receptor in relationship to biased agonism. Methods Enzymol (2013) 0.77
MicroRNA miR-182 cluster mediated modulation of RECK without changes in cell surface membrane type-1 matrix metalloproteinase (MT1-MMP). Am J Cancer Res (2015) 0.77
Rat forming incisor requires a rigorous ECM remodeling modulated by MMP/RECK balance. J Mol Histol (2009) 0.76
Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1). Oncotarget (2016) 0.76
Beta2-adaptin binds actopaxin and regulates cell spreading, migration and matrix degradation. PLoS One (2012) 0.76
Metalloproteinase binding proteins: WO2009097397. Expert Opin Ther Pat (2010) 0.75
Regulation of membrane type-1 matrix metalloproteinase activity and intracellular localization in clinical thoracic aortic aneurysms. J Thorac Cardiovasc Surg (2016) 0.75
MT1-MMP Inhibits the Activity of Bst-2 via Their Cytoplasmic Domains Dependent Interaction. Int J Mol Sci (2016) 0.75
Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts. J Biol Chem (2017) 0.75
Proactive for invasion: Reuse of matrix metalloproteinase for structural memory. J Cell Biol (2016) 0.75
Post-Translational Modification of the Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Cytoplasmic Tail Impacts Ovarian Cancer Multicellular Aggregate Dynamics. J Biol Chem (2017) 0.75
Matrix metalloproteinases. J Biol Chem (1999) 12.08
A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (1994) 9.31
Clathrin, adaptors, and sorting. Annu Rev Cell Biol (1990) 7.17
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell (1999) 6.40
ECM and cell surface proteolysis: regulating cellular ecology. Cell (1997) 6.00
Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem (1995) 5.57
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature (1991) 5.13
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc Natl Acad Sci U S A (2000) 4.22
GTPase activity of dynamin and resulting conformation change are essential for endocytosis. Nature (2001) 3.90
Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins. Cell (1998) 3.72
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol (2000) 3.53
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol (2001) 3.32
Matrix metalloproteinases in tumor invasion and metastasis. Semin Cancer Biol (2000) 3.13
Matrix metalloproteinases: structures, evolution, and diversification. FASEB J (1998) 2.74
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3. J Biol Chem (1996) 2.45
Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (1997) 2.39
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A (1997) 2.35
Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family. J Biol Chem (1995) 2.01
Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. J Biol Chem (1996) 1.98
Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem (1999) 1.89
Three-dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells. J Biol Chem (1998) 1.80
Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation. J Biol Chem (2000) 1.59
Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase. Int J Cancer (2000) 1.56
Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP. J Biol Chem (1999) 1.52
Stimulation-induced down-regulation of tumor necrosis factor-alpha converting enzyme. J Biol Chem (2000) 1.51
Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface. Biochem J (1998) 1.48
Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain. J Biol Chem (2000) 1.36
G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. J Biol Chem (1997) 1.36
Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur J Biochem (1996) 1.35
Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage. Cell Res (1999) 1.34
Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase. J Biol Chem (1999) 1.31
Subcellular distribution and cytokine- and chemokine-regulated secretion of leukolysin/MT6-MMP/MMP-25 in neutrophils. J Biol Chem (2001) 1.20
Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through beta1 integrin. Cancer Res (1999) 1.19
Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP. FEBS Lett (2000) 1.19
Collagen-induced activation of the M(r) 72,000 type IV collagenase in normal and malignant human fibroblastoid cells. Cancer Res (1992) 1.17
Membrane type 1 matrix metalloproteinase-associated degradation of tissue inhibitor of metalloproteinase 2 in human tumor cell lines. J Biol Chem (2000) 1.02
Functional characterization of MT3-MMP in transfected MDCK cells: progelatinase A activation and tubulogenesis in 3-D collagen lattice. FASEB J (2000) 0.97
Cysteine array matrix metalloproteinase (CA-MMP)/MMP-23 is a type II transmembrane matrix metalloproteinase regulated by a single cleavage for both secretion and activation. J Biol Chem (2000) 0.97
Expression of membrane type 1 matrix metalloproteinase in human articular cartilage. Arthritis Rheum (1997) 0.93
Matrix metalloproteinases and coronary artery disease: a novel therapeutic target. J Clin Pharmacol (1997) 0.89
Mighty mice: transgenic technology "knocks out" questions of matrix metalloproteinase function. Matrix Biol (1997) 0.87
The sequence of the human genome. Science (2001) 101.55
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell (1997) 24.57
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell (1996) 16.73
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science (1997) 16.09
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell (1998) 13.87
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science (2000) 13.62
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell (1997) 12.83
Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. Science (2000) 12.35
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell (2000) 11.90
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev (1998) 11.86
Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med (2000) 11.35
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature (2000) 9.80
Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol (1999) 8.21
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell (1993) 6.95
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem (1999) 6.88
HOLE: a program for the analysis of the pore dimensions of ion channel structural models. J Mol Graph (1996) 6.48
Endonuclease G is an apoptotic DNase when released from mitochondria. Nature (2001) 6.20
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell (1997) 5.95
Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol (2000) 5.81
Speech recognition in noise as a function of the number of spectral channels: comparison of acoustic hearing and cochlear implants. J Acoust Soc Am (2001) 5.75
The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc Natl Acad Sci U S A (2000) 5.46
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Proc Natl Acad Sci U S A (2000) 5.38
DNA microarray-mediated transcriptional profiling of the Escherichia coli response to hydrogen peroxide. J Bacteriol (2001) 5.35
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci (2001) 4.99
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med (2001) 4.71
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc Natl Acad Sci U S A (1993) 4.61
POWER_SAGE: comparing statistical tests for SAGE experiments. Bioinformatics (2000) 4.56
Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography. Opt Lett (1997) 4.48
Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. J Exp Med (1987) 4.35
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J Cell Biol (1988) 4.34
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res (1999) 4.23
Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol (1996) 4.11
Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J Biol Chem (1998) 4.02
Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science (1991) 3.96
Treatment of supraventricular tachycardia due to atrioventricular nodal reentry, by radiofrequency catheter ablation of slow-pathway conduction. N Engl J Med (1992) 3.95
Interstitial cells of Cajal mediate cholinergic neurotransmission from enteric motor neurons. J Neurosci (2000) 3.95
Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors. Proc Natl Acad Sci U S A (1998) 3.94
Multiple transcription-factor genes are early targets of phytochrome A signaling. Proc Natl Acad Sci U S A (2001) 3.91
Language comprehension in language-learning impaired children improved with acoustically modified speech. Science (1996) 3.84
The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci U S A (1998) 3.83
Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins. Cell (1998) 3.72
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nat Photonics (2012) 3.68
Structural basis of IAP recognition by Smac/DIABLO. Nature (2001) 3.66
Temporal and rate representations of time-varying signals in the auditory cortex of awake primates. Nat Neurosci (2001) 3.62
High-throughput genotyping with single nucleotide polymorphisms. Genome Res (2001) 3.55
Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature (2000) 3.54
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol (2000) 3.53
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest (1998) 3.51
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway. Nat Cell Biol (1999) 3.45
Association of Rab25 and Rab11a with the apical recycling system of polarized Madin-Darby canine kidney cells. Mol Biol Cell (1999) 3.45
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis. Cell (2000) 3.39
Myocyte death in the failing human heart is gender dependent. Circ Res (1999) 3.38
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem (1996) 3.38
Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation. J Clin Invest (1982) 3.33
Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium. Proc Natl Acad Sci U S A (2000) 3.32
Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology (1995) 3.26
Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem (1994) 3.09
Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J Biol Chem (1993) 3.04
Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells. J Clin Invest (1981) 2.97
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest (1997) 2.93
Mobile microbiome: oral bacteria in extra-oral infections and inflammation. J Dent Res (2013) 2.89
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell (1998) 2.89
Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO J (1995) 2.87
Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages. Proc Natl Acad Sci U S A (1995) 2.84
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest (1999) 2.77
Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature (2001) 2.76
Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat Cell Biol (2000) 2.74
Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. J Clin Invest (1987) 2.74
Growth factors in the extracellular matrix. FASEB J (1997) 2.71
Radiofrequency catheter ablation of idiopathic left ventricular tachycardia guided by a Purkinje potential. Circulation (1993) 2.71
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest (2001) 2.67
Development and validation of an ECG algorithm for identifying accessory pathway ablation site in Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol (1998) 2.59
Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes. Circ Res (2001) 2.56
Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia. Circ Res (2001) 2.55
Human granulocyte generation of hydroxyl radical. J Exp Med (1978) 2.54
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis (2013) 2.52
Increasing the completion of the durable power of attorney for health care. A randomized, controlled trial. JAMA (1994) 2.48
Effects of noise and spectral resolution on vowel and consonant recognition: acoustic and electric hearing. J Acoust Soc Am (1998) 2.46
Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia. Brain Pathol (2000) 2.46
Comparison of in vivo tissue temperature profile and lesion geometry for radiofrequency ablation with a saline-irrigated electrode versus temperature control in a canine thigh muscle preparation. Circulation (1995) 2.45
Abrogation of the alternative complement pathway by targeted deletion of murine factor B. Proc Natl Acad Sci U S A (1997) 2.44
Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta. J Cell Biol (1986) 2.44
Phagocyte-generated oxygen metabolites and cellular injury. Lab Invest (1982) 2.43
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J Biol Chem (2000) 2.42
Long-term outcomes in nondiabetic chronic kidney disease. Kidney Int (2008) 2.41
Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature (1995) 2.40
Oxidative autoactivation of latent collagenase by human neutrophils. Science (1985) 2.40
The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. J Clin Invest (1996) 2.39
Acute effects of total suspended particles and sulfur dioxides on preterm delivery: a community-based cohort study. Arch Environ Health (1996) 2.39
Consonant recordings for speech testing. J Acoust Soc Am (1999) 2.38
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc Natl Acad Sci U S A (1998) 2.38
A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee. Arthritis Rheum (2001) 2.37
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology (2010) 2.36
Identification of a novel class of insect glutathione S-transferases involved in resistance to DDT in the malaria vector Anopheles gambiae. Biochem J (2001) 2.35
Torque generation in the flagellar motor of Escherichia coli: evidence of a direct role for FliG but not for FliM or FliN. J Bacteriol (1996) 2.32
Effects of cigarette smoking on lung function in adolescent boys and girls. N Engl J Med (1996) 2.31