Published in J Biol Chem on December 15, 1990
Type II restriction endonucleases--a historical perspective and more. Nucleic Acids Res (2014) 1.22
In vivo specificity of EcoRI DNA methyltransferase. Nucleic Acids Res (1992) 0.81
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
A complementation analysis of the restriction and modification of DNA in Escherichia coli. J Mol Biol (1969) 71.21
Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA. Proc Natl Acad Sci U S A (1974) 32.46
Construction of biologically functional bacterial plasmids in vitro. Proc Natl Acad Sci U S A (1973) 25.61
Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages and other viruses by agarose-gel electrophoresis. J Virol (1974) 23.54
DNA nucleotide sequence restricted by the RI endonuclease. Proc Natl Acad Sci U S A (1972) 15.71
Sequence-specific recognition of double helical nucleic acids by proteins. Proc Natl Acad Sci U S A (1976) 13.30
Construction and characterization of new cloning vehicles. I. Ampicillin-resistant derivatives of the plasmid pMB9. Gene (1977) 12.93
Specificity of substrate recognition by the EcoRI restriction endonuclease. Proc Natl Acad Sci U S A (1975) 11.07
Replication and transcription of eukaryotic DNA in Escherichia coli. Proc Natl Acad Sci U S A (1974) 10.51
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. Science (1977) 9.28
Protein expression in E. coli minicells by recombinant plasmids. Cell (1977) 8.74
A general method for the purification of restriction enzymes. Nucleic Acids Res (1978) 7.92
Characterization of a mini-ColC1 plasmid. J Bacteriol (1976) 7.20
Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structures. J Mol Biol (1975) 6.95
DNA restriction and modification mechanisms in bacteria. Annu Rev Microbiol (1971) 6.05
DNA substrate site for the EcoRII restriction endonuclease and modification methylase. Nat New Biol (1973) 5.90
Synthetic lac operator DNA is functional in vivo. Nature (1976) 5.36
Restriction and modification of DNA: enzymes and substrates. Introductory remarks. Fed Proc (1974) 5.31
The Escherichia coli B restriction endonuclease. Biochim Biophys Acta (1969) 5.00
Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution. Science (1986) 4.89
Chemical synthesis of restriction enzyme recognition sites useful for cloning. Science (1977) 4.81
Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the Eco RI restriction endonuclease and modification methylase. Biochemistry (1974) 4.58
Restriction and modification of a self-complementary octanucleotide containing the EcoRI substrate. J Mol Biol (1975) 4.21
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
A restriction endonuclease analysis of the bacterial plasmid controlling the ecoRI restriction and modification of DNA. Fed Proc (1976) 3.04
Altered tetracycline resistance in pSC101 recombinant plasmids. Mol Gen Genet (1977) 3.03
Double helix at atomic resolution. Nature (1973) 2.84
On the nature of tetracycline resistance controlled by the plasmid pSC101. Cell (1978) 2.80
Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing. Science (1990) 2.74
R factor-controlled restriction and modification of deoxyribonucleic acid: restriction mutants. J Bacteriol (1972) 2.65
Sequence analysis of the DNA encoding the Eco RI endonuclease and methylase. J Biol Chem (1981) 2.62
Kinked DNA in crystalline complex with EcoRI endonuclease. Nature (1984) 2.46
Origin of replication of pBR345 plasmid DNA. Proc Natl Acad Sci U S A (1977) 2.40
A crystalline fragment of the double helix: the structure of the dinucleoside phosphate guanylyl-3',5'-cytidine. Proc Natl Acad Sci U S A (1973) 2.39
Characterization of a halobacterial gene affecting bacterio-opsin gene expression. Nucleic Acids Res (1984) 2.37
RNA double-helical fragments at atomic resolution. I. The crystal and molecular structure of sodium adenylyl-3',5'-uridine hexahydrate. J Mol Biol (1976) 2.25
The bone induction principle. Clin Orthop Relat Res (1968) 2.23
Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313. Nucleic Acids Res (1979) 2.23
Genetic and physical studies on the replication of ColE1-type plasmids. Cold Spring Harb Symp Quant Biol (1979) 2.15
Interaction of bacteriophage T4 RNA and DNA ligases in joining of duplex DNA at base-paired ends. J Biol Chem (1977) 2.13
RNA double-helical fragments at atomic resolution. II. The crystal structure of sodium guanylyl-3',5'-cytidine nonahydrate. J Mol Biol (1976) 2.07
The structures and fidelity of replication of mouse mitochondrial DNA-pSC 101 EcoRI recombinant plasmids grown in E. coli K12. Cell (1976) 2.02
Bacterio-opsin mutants of Halobacterium halobium. Proc Natl Acad Sci U S A (1983) 1.91
Developmental expression of urine concentration-associated genes and their altered expression in murine infantile-type polycystic kidney disease. Dev Genet (1999) 1.80
Effect of silicon on gastrointestinal absorption of aluminium. Lancet (1993) 1.80
Production of two proteolytic enzymes by a transformable strain of Bacillus subtilis. Arch Biochem Biophys (1968) 1.74
Genomic instability induced by ionizing radiation. Radiat Res (1996) 1.73
Radial artery pressure monitoring underestimates central arterial pressure during vasopressor therapy in critically ill surgical patients. Crit Care Med (1998) 1.72
Aluminum neurotoxicity in preterm infants receiving intravenous-feeding solutions. N Engl J Med (1997) 1.71
Molecular cloning of an Escherichia coli plasmid determinant than encodes for the production of heat-stable enterotoxin. J Bacteriol (1976) 1.69
Simultaneous aortic, jugular bulb, and right atrial pressures during cardiopulmonary resuscitation in humans. Insights into mechanisms. Circulation (1989) 1.69
Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes. Nucleic Acids Res (1996) 1.68
Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2. Nat Biotechnol (2000) 1.66
Genetic control of the secondary modification of deoxyribonucleic acid in Escherichia coli. J Bacteriol (1970) 1.63
Characterization of insertions affecting the expression of the bacterio-opsin gene in Halobacterium halobium. Nucleic Acids Res (1984) 1.59
Improved analysis of picomole quantities of lithium, sodium, and potassium in biological fluids. Am J Physiol (1994) 1.57
Nanometal surface energy transfer in optical rulers, breaking the FRET barrier. J Am Chem Soc (2005) 1.48
The structure of cauliflower mosaic virus. I. A restriction endonuclease map of cauliflower mosaic virus DNA. Virology (1977) 1.48
Targeted base stacking disruption by the EcoRI DNA methyltransferase. Biochemistry (1996) 1.46
Restoration of bacterioopsin gene expression in a revertant of Halobacterium halobium. J Bacteriol (1985) 1.43
Electron microscopic mapping of the attachment sites on SV40 DNA during lytic infection. Cold Spring Harb Symp Quant Biol (1975) 1.42
Concerning CERRIE's conclusions and COMARE's response on doses and risks from internal emitters. J Radiol Prot (2005) 1.38
Kinetic studies of inducer binding to lac repressor.operator complex. J Biol Chem (1980) 1.35
Coordinate ion pair formation between EcoRI endonuclease and DNA. J Biol Chem (1983) 1.30
Tetracycline resistance determined by pBR322 is mediated by one polypeptide. Gene (1983) 1.27
Role of the nonheme Fe(II) center in the biosynthesis of the plant hormone ethylene. Proc Natl Acad Sci U S A (1999) 1.27
Solubility and dialysis limits of DNA oligonucleotides. Biochim Biophys Acta (1972) 1.26
Kinetics of uptake and elimination of silicic acid by a human subject: a novel application of 32Si and accelerator mass spectrometry. J Inorg Biochem (1998) 1.26
Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences. Biochemistry (1996) 1.24
Oligomeric but not monomeric silica prevents aluminum absorption in humans. Am J Clin Nutr (2000) 1.24
Mapping simian virus 40 mutants by construction of partial heterozygotes. J Virol (1975) 1.22
Molecular dynamics simulation study of DNA dodecamer d(CGCGAATTCGCG) in solution: conformation and hydration. J Mol Biol (1997) 1.21
Positive-selection vectors utilizing lethality of the EcoRI endonuclease. Gene (1986) 1.21
Exposition of a family of RNA m(5)C methyltransferases from searching genomic and proteomic sequences. Nucleic Acids Res (1999) 1.21
Structual comparison of ectopic and normal placental alkaline phosphatase. Proc Natl Acad Sci U S A (1973) 1.20
Lac repressor purification without inactivation of DNA binding activity. Nucleic Acids Res (1977) 1.20
Comparison of the nucleotide and amino acid sequences of the RsrI and EcoRI restriction endonucleases. Gene (1989) 1.19
Size and base composition of RNA in supercoiled plasmid DNA. Proc Natl Acad Sci U S A (1973) 1.19
Antioxidant therapy for recurrent pancreatitis: biochemical profiles in a placebo-controlled trial. Aliment Pharmacol Ther (1992) 1.18
Equilibrium binding of inducer to lac repressor.operator DNA complex. J Biol Chem (1980) 1.17
Eco RI* specificity and hydrogen bonding. DNA (1982) 1.16
RNA double helices generated from crystal structures of double helical dinucleoside phosphates. Biochem Biophys Res Commun (1976) 1.16
Measurement of the absolute temporal coupling between DNA binding and base flipping. Biochemistry (1999) 1.15
Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA. Biochemistry (1998) 1.14
Sequence of the 3'-noncoding and adjacent coding regions of human gamma-globin mRNA. Nucleic Acids Res (1978) 1.14
Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease. Nat Struct Biol (1999) 1.14
Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes. J Mol Cell Cardiol (2011) 1.14