Published in J Nutr Biochem on May 07, 2012
Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models. Drug Des Devel Ther (2014) 0.77
The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity. Int J Obes (Lond) (2013) 0.77
Indole-3-carbinol protects against cisplatin-induced acute nephrotoxicity: role of calcitonin gene-related peptide and insulin-like growth factor-1. Sci Rep (2016) 0.76
Suppression of Lipid Accumulation by Indole-3-Carbinol Is Associated with Increased Expression of the Aryl Hydrocarbon Receptor and CYP1B1 Proteins in Adipocytes and with Decreased Adipocyte-Stimulated Endothelial Tube Formation. Int J Mol Sci (2016) 0.75
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans. Brain Struct Funct (2010) 1.71
Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. J Agric Food Chem (2002) 1.64
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. Mol Cell (2012) 1.50
Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice. Biochem Pharmacol (2011) 1.32
Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc (2011) 1.30
Myricetin suppresses UVB-induced skin cancer by targeting Fyn. Cancer Res (2008) 1.29
Tpl2 is a key mediator of arsenite-induced signal transduction. Cancer Res (2009) 1.26
Naturally occurring phytochemicals for the prevention of Alzheimer's disease. J Neurochem (2009) 1.25
The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr (2005) 1.24
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer Res (2008) 1.20
Resveratrol directly targets COX-2 to inhibit carcinogenesis. Mol Carcinog (2008) 1.17
Long-term effects of resveratrol supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient mice. Biochem Biophys Res Commun (2008) 1.16
Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}. J Biol Chem (2010) 1.12
Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells. Cardiovasc Res (2009) 1.10
Impacts of changes in climate and land use/land cover under IPCC RCP scenarios on streamflow in the Hoeya River Basin, Korea. Sci Total Environ (2013) 1.08
Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer. Cancer Res (2010) 1.07
The von Economo neurons in the frontoinsular and anterior cingulate cortex. Ann N Y Acad Sci (2011) 1.07
Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis (2008) 1.07
Ilex paraguariensis extract ameliorates obesity induced by high-fat diet: potential role of AMPK in the visceral adipose tissue. Arch Biochem Biophys (2008) 1.07
Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity. BMC Genomics (2012) 1.03
Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity. Biochem Pharmacol (2010) 1.03
Variation in major antioxidants and total antioxidant activity of Yuzu (Citrus junos Sieb ex Tanaka) during maturation and between cultivars. J Agric Food Chem (2004) 1.03
Anti-obesity effects of Juniperus chinensis extract are associated with increased AMP-activated protein kinase expression and phosphorylation in the visceral adipose tissue of rats. Biol Pharm Bull (2008) 1.03
de Quervain disease: US identification of anatomic variations in the first extensor compartment with an emphasis on subcompartmentalization. Radiology (2011) 1.01
Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice. J Nutr Biochem (2011) 1.00
T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation. Cancer Res (2007) 1.00
DNA microarrays to define and search for genes associated with obesity. Biotechnol J (2010) 1.00
Assessment of exposure to heavy metals and health risks among residents near abandoned metal mines in Goseong, Korea. Environ Pollut (2013) 0.99
Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis. Pharmacol Ther (2011) 0.98
A mixture of the aqueous extract of Garcinia cambogia, soy peptide and L: -carnitine reduces the accumulation of visceral fat mass in rats rendered obese by a high fat diet. Genes Nutr (2008) 0.98
Interpreting positive signs of the supraspinatus test in screening for torn rotator cuff. Acta Med Okayama (2006) 0.98
1H-nuclear magnetic resonance spectroscopy-based metabolic assessment in a rat model of obesity induced by a high-fat diet. Anal Bioanal Chem (2009) 0.98
Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. Carcinogenesis (2011) 0.97
Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice. Breast Cancer Res (2011) 0.96
Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. Cancer Prev Res (Phila) (2011) 0.96
The von Economo neurons in apes and humans. Am J Hum Biol (2010) 0.96
Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase. Carcinogenesis (2009) 0.96
Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice. Food Chem (2013) 0.96
Genes are differentially expressed in the epididymal fat of rats rendered obese by a high-fat diet. Nutr Res (2008) 0.96
Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice. J Hepatol (2010) 0.94
Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation. J Biol Chem (2012) 0.94
Psychiatric symptom versus neurocognitive correlates of diminished expressivity in schizophrenia and mood disorders. Schizophr Res (2013) 0.94
Protective effect of quercetin against arsenite-induced COX-2 expression by targeting PI3K in rat liver epithelial cells. J Agric Food Chem (2010) 0.94
Zolpidem use and risk of fracture in elderly insomnia patients. J Prev Med Public Health (2012) 0.94
Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin. Int J Biochem Cell Biol (2009) 0.93
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol (2015) 0.93
On the boundaries of blunt affect/alogia across severe mental illness: implications for Research Domain Criteria. Schizophr Res (2012) 0.93
Reciprocal regulation of the autophosphorylation of enzyme INtr by glutamine and α-ketoglutarate in Escherichia coli. Mol Microbiol (2013) 0.93
Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells. Biopolymers (2014) 0.93
Src kinase is a direct target of apigenin against UVB-induced skin inflammation. Carcinogenesis (2012) 0.93
6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. Carcinogenesis (2011) 0.93
Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase. J Biol Chem (2008) 0.92
A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. Mol Carcinog (2011) 0.92
Ruthenium-catalyzed Heck-type olefination and Suzuki coupling reactions: studies on the nature of catalytic species. J Am Chem Soc (2004) 0.91
Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells. Ann N Y Acad Sci (2007) 0.91
Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission. J Biol Chem (2013) 0.91
Rhodium-catalyzed isomerization of unactivated alkynes to 1,3-dienes. Chem Commun (Camb) (2006) 0.91
Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway. J Biol Chem (2007) 0.91
Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin. Cancer Prev Res (Phila) (2013) 0.90
Protective effects of piceatannol against beta-amyloid-induced neuronal cell death. Ann N Y Acad Sci (2007) 0.90
7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4. J Biol Chem (2011) 0.90
Garcinia cambogia extract ameliorates visceral adiposity in C57BL/6J mice fed on a high-fat diet. Biosci Biotechnol Biochem (2008) 0.89
Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice. Mamm Genome (2011) 0.89
High-fat diet-induced obesity increases lymphangiogenesis and lymph node metastasis in the B16F10 melanoma allograft model: roles of adipocytes and M2-macrophages. Int J Cancer (2014) 0.89
Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis. Ann N Y Acad Sci (2011) 0.89
Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1. Cancer Res (2010) 0.89
Eupatilin, a major flavonoid of Artemisia, attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities. Planta Med (2013) 0.89
Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK. Mutat Res (2008) 0.89
Detection of BRAF(V600E) Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing. Korean J Pathol (2012) 0.89
BRAF (V600E) mutation analysis in papillary thyroid carcinomas by peptide nucleic acid clamp real-time PCR. Ann Surg Oncol (2012) 0.89
Antioxidant activity of black tea vs. green tea. J Nutr (2002) 0.89
Extract from Dioscorea batatas ameliorates insulin resistance in mice fed a high-fat diet. J Med Food (2012) 0.88
Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling. Ann N Y Acad Sci (2009) 0.88
Carvacrol prevents diet-induced obesity by modulating gene expressions involved in adipogenesis and inflammation in mice fed with high-fat diet. J Nutr Biochem (2011) 0.88
Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells. Ann N Y Acad Sci (2007) 0.88
Caffeinated coffee, decaffeinated coffee, and the phenolic phytochemical chlorogenic acid up-regulate NQO1 expression and prevent H₂O₂-induced apoptosis in primary cortical neurons. Neurochem Int (2012) 0.88
Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. Biochem Pharmacol (2010) 0.88
Preventive effects of vitamin C on carcinogenesis. Lancet (2002) 0.88
5-deoxykaempferol plays a potential therapeutic role by targeting multiple signaling pathways in skin cancer. Cancer Prev Res (Phila) (2010) 0.87
7,3',4'-Trihydroxyisoflavone inhibits epidermal growth factor-induced proliferation and transformation of JB6 P+ mouse epidermal cells by suppressing cyclin-dependent kinases and phosphatidylinositol 3-kinase. J Biol Chem (2010) 0.87
Short-term weight loss attenuates local tissue inflammation and improves insulin sensitivity without affecting adipose inflammation in obese mice. Am J Physiol Endocrinol Metab (2013) 0.87
Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemia HL-60 cells. Biol Pharm Bull (2006) 0.87
Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf. Biochem Pharmacol (2010) 0.87
Piperine, an LXRα antagonist, protects against hepatic steatosis and improves insulin signaling in mice fed a high-fat diet. Biochem Pharmacol (2012) 0.87
Moritella dasanensis sp. nov., a psychrophilic bacterium isolated from the Arctic ocean. Int J Syst Evol Microbiol (2008) 0.87
20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol suppresses UV-Induced MMP-1 expression through AMPK-mediated mTOR inhibition as a downstream of the PKA-LKB1 pathway. J Cell Biochem (2014) 0.86
Cancer chemopreventive effects of lactic acid bacteria. J Microbiol Biotechnol (2007) 0.86
Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target. FEBS Lett (2005) 0.86
Phosphatidylinositol 3-kinase, a novel target molecule for the inhibitory effects of kaempferol on neoplastic cell transformation. Carcinogenesis (2010) 0.86
Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo. Carcinogenesis (2009) 0.86
Induction of apoptosis in a human lymphoma cell line by hydrophobic peptide fraction separated from anchovy sauce. Biofactors (2004) 0.86
Palladium-catalyzed asymmetric [3+3] cycloaddition of trimethylenemethane derivatives with nitrones. Angew Chem Int Ed Engl (2007) 0.86
Curcumin suppresses proliferation of colon cancer cells by targeting CDK2. Cancer Prev Res (Phila) (2014) 0.86
Quercetin suppresses MIP-1α-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling. J Med Food (2013) 0.86
Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity. Toxicol Appl Pharmacol (2010) 0.85
Protective effect of Codonopsis lanceolata root extract against alcoholic fatty liver in the rat. J Med Food (2009) 0.85