Published in FASEB J on May 16, 2012
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A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts. Thyroid (2012) 1.00
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Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor. FASEB J (2010) 0.94
Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor. FASEB J (2008) 0.93
TRH-receptor-type-2-deficient mice are euthyroid and exhibit increased depression and reduced anxiety phenotypes. Neuropsychopharmacology (2008) 0.93
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A small molecule antagonist inhibits thyrotropin receptor antibody-induced orbital fibroblast functions involved in the pathogenesis of Graves ophthalmopathy. J Clin Endocrinol Metab (2013) 0.93
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Understanding the structural and functional differences between mouse thyrotropin-releasing hormone receptors 1 and 2. Proteins (2008) 0.88
A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling. Endocrinology (2005) 0.88
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A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice. Endocrinology (2013) 0.86
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Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobins. J Clin Endocrinol Metab (2014) 0.85
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A novel activating mutation in transmembrane helix 6 of the thyrotropin receptor as cause of hereditary nonautoimmune hyperthyroidism. Thyroid (2006) 0.81
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Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1. Bioorg Med Chem (2006) 0.81
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High levels of thyrotropin-releasing hormone receptors activate programmed cell death in human pancreatic precursors. Pancreas (2009) 0.80
Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation. Stem Cells Dev (2013) 0.80
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A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: role of a conserved tryptophan in helix 6. Mol Pharmacol (2004) 0.80
A modified ELISA accurately measures secretion of high molecular weight hyaluronan (HA) by Graves' disease orbital cells. Endocrinology (2013) 0.79
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