Published in J Appl Physiol (1985) on May 17, 2012
CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society. Radiology (2015) 1.24
Diagnosis, assessment, and phenotyping of COPD: beyond FEV1. Int J Chron Obstruct Pulmon Dis (2016) 0.80
MicroCT Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema. Am J Respir Crit Care Med (2016) 0.75
Seeing may be believing. J Appl Physiol (1985) (2012) 0.75
Sources of variation in quantitative computed tomography of the lung. J Thorac Imaging (2013) 0.75
Computed tomography--an increasing source of radiation exposure. N Engl J Med (2007) 41.06
The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med (2004) 17.08
The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy (2004) 13.16
Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med (2009) 10.27
Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J (2008) 10.08
A randomized study of endobronchial valves for advanced emphysema. N Engl J Med (2010) 6.23
Optical coherence tomography for ultrahigh resolution in vivo imaging. Nat Biotechnol (2003) 5.29
Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. Am J Respir Crit Care Med (2000) 4.32
"Density mask". An objective method to quantitate emphysema using computed tomography. Chest (1988) 4.24
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med (2011) 4.16
Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 3.70
Comparison of computed density and macroscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med (1995) 3.45
Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes--initial experience. Radiology (2002) 3.30
The linear no-threshold relationship is inconsistent with radiation biologic and experimental data. Radiology (2009) 3.25
Airflow limitation and airway dimensions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2006) 3.09
The prediction of small airway dimensions using computed tomography. Am J Respir Crit Care Med (2004) 3.02
Comparison of computed density and microscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med (1996) 2.75
State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 2.60
Global Strategy for the Diagnosis, Management and Prevention of COPD: 2003 update. Eur Respir J (2003) 2.57
Intrathoracic airway trees: segmentation and airway morphology analysis from low-dose CT scans. IEEE Trans Med Imaging (2005) 2.49
Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography. Am J Respir Crit Care Med (2010) 2.43
Is computed tomography safe? N Engl J Med (2010) 2.41
Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer. Am J Respir Crit Care Med (2007) 2.39
A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis. Chest (2008) 2.38
Risks associated with low doses and low dose rates of ionizing radiation: why linearity may be (almost) the best we can do. Radiology (2009) 2.37
The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis (1993) 2.23
Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease. Thorax (2012) 2.15
CT measurements of lung density in life can quantitate distal airspace enlargement--an essential defining feature of human emphysema. Am Rev Respir Dis (1988) 2.06
Accurate measurement of intrathoracic airways. IEEE Trans Med Imaging (1997) 1.97
Identification of chronic obstructive pulmonary disease in lung cancer screening computed tomographic scans. JAMA (2011) 1.94
Pulmonary emphysema: objective quantification at multi-detector row CT--comparison with macroscopic and microscopic morphometry. Radiology (2006) 1.93
Airway wall thickness in asthma assessed by computed tomography. Relation to clinical indices. Am J Respir Crit Care Med (2000) 1.88
Measurement of lung expansion with computed tomography and comparison with quantitative histology. J Appl Physiol (1985) (1995) 1.81
Hyperpolarized 3He diffusion MRI and histology in pulmonary emphysema. Magn Reson Med (2006) 1.76
Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms. Am J Respir Crit Care Med (2009) 1.75
An analysis algorithm for measuring airway lumen and wall areas from high-resolution computed tomographic data. Am J Respir Crit Care Med (2000) 1.75
Measurement of the internal size of bronchi using high resolution computed tomography (HRCT) Eur Respir J (1994) 1.67
Airway wall thickness assessed using computed tomography and optical coherence tomography. Am J Respir Crit Care Med (2008) 1.64
Worldwide burden of COPD in high- and low-income countries. Part I. The burden of obstructive lung disease (BOLD) initiative. Int J Tuberc Lung Dis (2008) 1.63
Montelukast improves regional air-trapping due to small airways obstruction in asthma. Eur Respir J (2006) 1.61
Effect of short-term treatment with inhaled corticosteroid on airway wall thickening in asthma. Am J Med (2004) 1.53
Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers. Chest (2010) 1.52
Imaging of lung function using hyperpolarized helium-3 magnetic resonance imaging: Review of current and emerging translational methods and applications. J Magn Reson Imaging (2010) 1.51
Maximizing quantitative accuracy of lung airway lumen and wall measures obtained from X-ray CT imaging. J Appl Physiol (1985) (2003) 1.51
In vivo optical coherence tomography imaging of preinvasive bronchial lesions. Clin Cancer Res (2008) 1.50
Quantitative upper airway imaging with anatomic optical coherence tomography. Am J Respir Crit Care Med (2005) 1.44
Clinical relevance of airway remodelling in airway diseases. Eur Respir J (2007) 1.44
Quantitative analysis of pulmonary airway tree structures. Comput Biol Med (2005) 1.42
Airway narrowing in excised canine lungs measured by high-resolution computed tomography. J Appl Physiol (1985) (1992) 1.40
Two-dimensional and 3-dimensional optical coherence tomographic imaging of the airway, lung, and pleura. J Thorac Cardiovasc Surg (2005) 1.39
Human airway narrowing measured using high resolution computed tomography. Am J Respir Crit Care Med (1996) 1.37
Airway dimensions in COPD: relationships with clinical variables. Respir Med (2010) 1.30
Optical coherence tomography in the diagnosis of bronchial lesions. Lung Cancer (2005) 1.28
In vivo size and shape measurement of the human upper airway using endoscopic longrange optical coherence tomography. Opt Express (2003) 1.27
Quantitative computed tomography assessment of airway wall dimensions: current status and potential applications for phenotyping chronic obstructive pulmonary disease. Proc Am Thorac Soc (2008) 1.26
New and current clinical imaging techniques to study chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2009) 1.23
CT of a bronchial phantom. Factors affecting appearance and size measurements. Invest Radiol (1985) 1.13
Prediction of the rate of decline in FEV(1) in smokers using quantitative Computed Tomography. Thorax (2009) 1.12
Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway. Opt Express (2008) 1.11
Quantitative assessment of the airway wall using computed tomography and optical coherence tomography. Proc Am Thorac Soc (2009) 1.04
Diagnostic imaging in COPD. Semin Respir Crit Care Med (2010) 1.03
Hyperpolarized ³He magnetic resonance imaging: preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease. Eur J Radiol (2009) 1.01
Radiation doses to patients receiving computed tomography examinations in British Columbia. Can Assoc Radiol J (2006) 1.00
Chronic obstructive pulmonary disease: quantification of bronchodilator effects by using hyperpolarized ³He MR imaging. Radiology (2011) 0.98
Bronchial wall thickness: appropriate window settings for thin-section CT and radiologic-anatomic correlation. Radiology (1996) 0.98
Computed tomography assessment of lung volume changes after bronchial valve treatment. Eur Respir J (2008) 0.97
Quantitative pulmonary imaging using computed tomography and magnetic resonance imaging. Respirology (2012) 0.97
Quantifying tracheobronchial tree dimensions: methods, limitations and emerging techniques. Eur Respir J (2009) 0.93
Investigation of hyperpolarized 3He magnetic resonance imaging utility in examining human airway diameter behavior in asthma through comparison with high-resolution computed tomography. Acad Radiol (2008) 0.93
Measurement, reconstruction, and flow-field computation of the human pharynx with application to sleep apnea. IEEE Trans Biomed Eng (2010) 0.92
Development and testing of image-processing methods for the quantitative assessment of airway hyperresponsiveness from high-resolution CT images. J Comput Assist Tomogr (1997) 0.92
Frontiers in bronchoscopic imaging. Respirology (2012) 0.91
Distal airways in humans: dynamic hyperpolarized 3He MR imaging--feasibility. Radiology (2003) 0.86
Three-dimensional airway measurements and algorithms. Proc Am Thorac Soc (2008) 0.84
Phenotyping airway disease with optical coherence tomography. Respirology (2011) 0.81
The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med (2004) 17.08
Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med (2011) 5.69
Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res (2010) 5.17
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med (2011) 4.16
Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 3.70
Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. Am J Respir Crit Care Med (2012) 3.44
Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med (2007) 3.05
The prediction of small airway dimensions using computed tomography. Am J Respir Crit Care Med (2004) 3.02
COPD phenotypes in biomass smoke- versus tobacco smoke-exposed Mexican women. Eur Respir J (2013) 2.81
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One (2012) 2.52
Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology. Am J Respir Crit Care Med (2007) 2.04
A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet (2011) 1.98
Quantifying the extent of emphysema: factors associated with radiologists' estimations and quantitative indices of emphysema severity using the ECLIPSE cohort. Acad Radiol (2011) 1.88
Estimation of cancer mortality associated with repetitive computed tomography scanning. Am J Respir Crit Care Med (2005) 1.88
Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms. Am J Respir Crit Care Med (2009) 1.75
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. Am J Respir Crit Care Med (2013) 1.73
Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax (2012) 1.72
Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort. Eur Respir J (2013) 1.66
An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2015) 1.63
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Sci Transl Med (2009) 1.61
Pulmonary ventilation visualized using hyperpolarized helium-3 and xenon-129 magnetic resonance imaging: differences in COPD and relationship to emphysema. J Appl Physiol (1985) (2012) 1.60
The effects of radiation dose and CT manufacturer on measurements of lung densitometry. Chest (2007) 1.53
Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 1.51
The IBV Valve trial: a multicenter, randomized, double-blind trial of endobronchial therapy for severe emphysema. J Bronchology Interv Pulmonol (2014) 1.51
Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. Respir Med (2013) 1.41
Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Am J Respir Crit Care Med (2010) 1.36
Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc (2011) 1.28
The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease. PLoS One (2009) 1.28
Persistent pneumocystis colonization leads to the development of chronic obstructive pulmonary disease in a nonhuman primate model of AIDS. J Infect Dis (2010) 1.19
The association between small airway obstruction and emphysema phenotypes in COPD. Chest (2007) 1.18
Lung density is not altered following intense normobaric hypoxic interval training in competitive female cyclists. J Appl Physiol (1985) (2007) 1.18
High-resolution computed tomography imaging of airway disease in infants with cystic fibrosis. Am J Respir Crit Care Med (2005) 1.17
Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results. Respir Med (2011) 1.11
Multicentre European study for the treatment of advanced emphysema with bronchial valves. Eur Respir J (2012) 1.09
Changes in airway dimensions on computed tomography scans of children with cystic fibrosis. Am J Respir Crit Care Med (2005) 1.08
Computed tomography in the evaluation of cystic fibrosis lung disease. Am J Respir Crit Care Med (2005) 1.07
Micro-computed tomography measurements of peripheral lung pathology in chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 1.04
Canadian Cohort Obstructive Lung Disease (CanCOLD): Fulfilling the need for longitudinal observational studies in COPD. COPD (2012) 1.04
Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease. Radiology (2012) 1.03
α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest (2010) 1.02
Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema. COPD (2008) 1.00
Evidence for dysanapsis using computed tomographic imaging of the airways in older ex-smokers. J Appl Physiol (1985) (2009) 1.00
Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD. Pulm Med (2011) 0.99
Quantitative CT measures of emphysema and airway wall thickness are related to D(L)CO. Respir Med (2010) 0.99
Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol (2009) 0.98
Quantitative pulmonary imaging using computed tomography and magnetic resonance imaging. Respirology (2012) 0.97
Reduced radiation dose helical chest CT: effect on reader evaluation of structures and lung findings. Radiology (2004) 0.96
On the role of abnormal DL(CO) in ex-smokers without airflow limitation: symptoms, exercise capacity and hyperpolarised helium-3 MRI. Thorax (2013) 0.95
Telomere length and chronic obstructive pulmonary disease: evidence of accelerated aging. J Am Geriatr Soc (2009) 0.95
Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. BMC Pulm Med (2014) 0.93
Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes? Ann Nutr Metab (2013) 0.91
Relationship between pathologic characteristics of peripheral airways and outcome after lung volume reduction surgery in severe chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 0.89
Effect of fluticasone propionate/salmeterol on arterial stiffness in patients with COPD. Respir Med (2011) 0.89
Airway and parenchymal disease in chronic obstructive pulmonary disease are distinct phenotypes. Proc Am Thorac Soc (2006) 0.86
New 133Xe gas trapping index for quantifying severe emphysema before partial lung volume reduction. J Nucl Med (2008) 0.84
Hyperpolarized (3)He ventilation defects used to predict pulmonary exacerbations in mild to moderate chronic obstructive pulmonary disease. Radiology (2014) 0.84
Ultra-short echo-time pulmonary MRI: evaluation and reproducibility in COPD subjects with and without bronchiectasis. J Magn Reson Imaging (2014) 0.84
Use of CT morphometry to detect changes in lung weight and gas volume. Chest (2005) 0.84
Impact of emphysema and airway wall thickness on quality of life in smoking-related COPD. Respir Med (2013) 0.83
What to do when a smoker's CT scan is "normal"?: Implications for lung cancer screening. Chest (2012) 0.83
Quantification of lung surface area using computed tomography. Respir Res (2010) 0.83
Qualitative and quantitative assessment of smoking-related lung disease: effect of iterative reconstruction on low-dose computed tomographic examinations. J Thorac Imaging (2014) 0.82
DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. Respir Res (2014) 0.82
Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Ann Am Thorac Soc (2014) 0.82
What are ventilation defects in asthma? Thorax (2013) 0.82
Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema. Eur Respir J (2013) 0.82
Detection of lung perfusion abnormalities using computed tomography in a porcine model of pulmonary embolism. J Thorac Imaging (2003) 0.81
Conventional high-resolution CT versus contiguous multidetector CT in the detection of bronchiolitis obliterans syndrome in lung transplant recipients. J Thorac Imaging (2008) 0.79
Diffusing capacity for carbon monoxide correlates best with tissue volume from quantitative CT scanning analysis. Chest (2015) 0.79
Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol (2014) 0.78
Bronchiolitis in young female smokers. Respir Med (2013) 0.77
Pulmonary abnormalities and carotid atherosclerosis in ex-smokers without airflow limitation. COPD (2014) 0.77
Pulmonary functional magnetic resonance imaging for paediatric lung disease. Paediatr Respir Rev (2013) 0.77
Computed tomography biomarkers of pulmonary emphysema. COPD (2013) 0.76
Using computed tomography to measure the site of airflow obstruction. Respirology (2012) 0.76
Uncovering the bronchovascular links in patients with chronic obstructive pulmonary disease with pulmonary hypertension. Am J Respir Crit Care Med (2015) 0.75
Phenotyping COPD using high resolution CT. Is it time to leave it for Watson? COPD (2012) 0.75
CT-Directed microcoil localization of small peripheral lung nodules: a feasibility study in pigs. J Invest Surg (2005) 0.75
Tomographic comparison of ventilation techniques for CT-guided thoracoscopic staple excision of subcentimeter lung nodules. J Invest Surg (2006) 0.75
Increased Ratio of Visceral to Subcutaneous Adipose Tissue in Septic Patients Is Associated With Adverse Outcome. Crit Care Med (2016) 0.75
A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography. Respiration (2017) 0.75