Published in Am J Hum Genet on December 01, 2007
A data-adaptive sum test for disease association with multiple common or rare variants. Hum Hered (2010) 5.95
A powerful and flexible multilocus association test for quantitative traits. Am J Hum Genet (2008) 4.96
Asymptotic tests of association with multiple SNPs in linkage disequilibrium. Genet Epidemiol (2009) 3.96
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Comparison of statistical tests for disease association with rare variants. Genet Epidemiol (2011) 3.42
Avoiding the high Bonferroni penalty in genome-wide association studies. Genet Epidemiol (2010) 2.79
Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet (2009) 2.30
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Hum Mol Genet (2008) 2.12
SNP set association analysis for familial data. Genet Epidemiol (2012) 2.08
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes (2008) 2.01
Leveraging genetic variability across populations for the identification of causal variants. Am J Hum Genet (2010) 2.00
Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets. Hum Genet (2011) 1.93
Integrating functional data to prioritize causal variants in statistical fine-mapping studies. PLoS Genet (2014) 1.91
Sample size requirements to detect gene-environment interactions in genome-wide association studies. Genet Epidemiol (2011) 1.78
PRESTO: rapid calculation of order statistic distributions and multiple-testing adjusted P-values via permutation for one and two-stage genetic association studies. BMC Bioinformatics (2008) 1.71
1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data. Eur J Hum Genet (2012) 1.59
CREB1 is a strong genetic predictor of the variation in exercise heart rate response to regular exercise: the HERITAGE Family Study. Circ Cardiovasc Genet (2010) 1.52
Bitter taste receptors influence glucose homeostasis. PLoS One (2008) 1.44
A general method for controlling the genome-wide type I error rate in linkage and association mapping experiments in plants. Heredity (Edinb) (2010) 1.44
A powerful and adaptive association test for rare variants. Genetics (2014) 1.40
Genetic variation in genes involved in hormones, inflammation and energetic factors and breast cancer risk in an admixed population. Carcinogenesis (2012) 1.40
PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies. Bioinformatics (2011) 1.39
Multiple testing corrections for imputed SNPs. Genet Epidemiol (2011) 1.36
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics (2014) 1.31
Genome-wide association analysis for multiple continuous secondary phenotypes. Am J Hum Genet (2013) 1.29
Gene-based testing of interactions in association studies of quantitative traits. PLoS Genet (2013) 1.23
Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes. Arch Gen Psychiatry (2011) 1.22
Efficient genome-wide association testing of gene-environment interaction in case-parent trios. Am J Epidemiol (2010) 1.22
Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. Carcinogenesis (2010) 1.19
A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians. Hum Mol Genet (2010) 1.18
Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence. Neuropsychopharmacology (2010) 1.17
Inherited variation in immune genes and pathways and glioblastoma risk. Carcinogenesis (2010) 1.17
JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Mol Carcinog (2011) 1.16
Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 1.15
Weighted multiple hypothesis testing procedures. Stat Appl Genet Mol Biol (2009) 1.14
Test selection with application to detecting disease association with multiple SNPs. Hum Hered (2009) 1.14
Linkage disequilibrium based association mapping of fiber quality traits in G. hirsutum L. variety germplasm. Genetica (2008) 1.13
Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Carcinogenesis (2010) 1.12
Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. Int J Cancer (2011) 1.12
Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway. Carcinogenesis (2010) 1.11
Schizophrenic patients and their unaffected siblings share increased resting-state connectivity in the task-negative network but not its anticorrelated task-positive network. Schizophr Bull (2010) 1.10
Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects. PLoS One (2010) 1.10
The effects of aging on N-methyl-D-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory. Neuroscience (2009) 1.08
PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study. J Thromb Haemost (2008) 1.08
MAX-rank: a simple and robust genome-wide scan for case-control association studies. Hum Genet (2008) 1.08
Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev (2010) 1.07
Powerful multi-marker association tests: unifying genomic distance-based regression and logistic regression. Genet Epidemiol (2010) 1.07
A non-human primate system for large-scale genetic studies of complex traits. Hum Mol Genet (2012) 1.05
Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival. Carcinogenesis (2011) 1.05
Kernel machine SNP-set testing under multiple candidate kernels. Genet Epidemiol (2013) 1.04
Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence. Cancer Res (2010) 1.04
Genetic determinants of immune-response to a polysaccharide vaccine for typhoid. Hugo J (2010) 1.04
Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology (2009) 1.04
Association of KLK3 (PSA) genetic variants with prostate cancer risk and PSA levels. Carcinogenesis (2011) 1.04
Adjustment for population stratification via principal components in association analysis of rare variants. Genet Epidemiol (2012) 1.03
Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol Biomarkers Prev (2010) 1.03
Roles of arginase variants, atopy, and ozone in childhood asthma. J Allergy Clin Immunol (2009) 1.03
A general framework for association tests with multivariate traits in large-scale genomics studies. Genet Epidemiol (2013) 1.03
Efficient association study design via power-optimized tag SNP selection. Ann Hum Genet (2008) 1.01
Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Clin Cancer Res (2011) 1.00
Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk. Cancer Epidemiol Biomarkers Prev (2012) 1.00
Statistical Methods for Mapping Multiple QTL. Int J Plant Genomics (2008) 1.00
Genetic variation in bone morphogenetic protein and colon and rectal cancer. Int J Cancer (2011) 0.99
Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose. Diabetes (2009) 0.99
Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans. Obesity (Silver Spring) (2009) 0.99
A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 0.99
Meta-analysis of genetic association studies and adjustment for multiple testing of correlated SNPs and traits. Genet Epidemiol (2010) 0.99
Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE study. Hum Mutat (2011) 0.98
Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry. Carcinogenesis (2010) 0.96
A powerful test for multiple rare variants association studies that incorporates sequencing qualities. Nucleic Acids Res (2012) 0.96
IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry. Carcinogenesis (2012) 0.95
Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. Carcinogenesis (2010) 0.95
Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma. Cancer Epidemiol Biomarkers Prev (2010) 0.94
Pearson's test, trend test, and MAX are all trend tests with different types of scores. Ann Hum Genet (2009) 0.93
Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function. Am J Respir Crit Care Med (2009) 0.93
FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans. Carcinogenesis (2011) 0.92
Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control (2009) 0.92
Design and analysis of multiple diseases genome-wide association studies without controls. Gene (2012) 0.92
Efficient p-value evaluation for resampling-based tests. Biostatistics (2011) 0.92
The cost of large numbers of hypothesis tests on power, effect size and sample size. Mol Psychiatry (2010) 0.91
Polymorphic variation in the GC and CASR genes and associations with vitamin D metabolite concentration and metachronous colorectal neoplasia. Cancer Epidemiol Biomarkers Prev (2011) 0.90
P-selectin genotype is associated with the development of cancer cachexia. EMBO Mol Med (2012) 0.89
Variation in the CYP19A1 gene and risk of colon and rectal cancer. Cancer Causes Control (2011) 0.89
Adaptive tests for detecting gene-gene and gene-environment interactions. Hum Hered (2011) 0.88
Utilising family-based designs for detecting rare variant disease associations. Ann Hum Genet (2014) 0.88
Association of genetic polymorphisms in cell-cycle control genes and susceptibility to endometrial cancer among Chinese women. Am J Epidemiol (2011) 0.88
The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort. Breast Cancer Res (2011) 0.88
Plasma cytokine levels and risk of HIV type 1 (HIV-1) transmission and acquisition: a nested case-control study among HIV-1-serodiscordant couples. J Infect Dis (2014) 0.88
A fast multilocus test with adaptive SNP selection for large-scale genetic-association studies. Eur J Hum Genet (2013) 0.88
Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes. Pharmacogenomics J (2011) 0.87
Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics. PLoS Comput Biol (2016) 0.86
Genetic linkage of region containing the CREB1 gene to depressive disorders in families with recurrent, early-onset, major depression: a re-analysis and confirmation of sex-specific effect. Am J Med Genet B Neuropsychiatr Genet (2010) 0.86
Genetic associations between neuregulin-1 SNPs and neurocognitive function in multigenerational, multiplex schizophrenia families. Psychiatr Genet (2012) 0.86
TAS2R bitter taste receptors regulate thyroid function. FASEB J (2014) 0.86
Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer. PLoS One (2012) 0.86
Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in Singapore Chinese women. Cancer Epidemiol Biomarkers Prev (2012) 0.86
TERT's role in colorectal carcinogenesis. Mol Carcinog (2012) 0.86
An Adaptive Association Test for Multiple Phenotypes with GWAS Summary Statistics. Genet Epidemiol (2015) 0.85
Multilocus association testing with penalized regression. Genet Epidemiol (2011) 0.85
Tumor necrosis factor-related genes and colon and rectal cancer. Int J Mol Epidemiol Genet (2011) 0.85
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet (2004) 14.76
Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity (Edinb) (2005) 9.85
A shrinkage approach to large-scale covariance matrix estimation and implications for functional genomics. Stat Appl Genet Mol Biol (2005) 9.57
Truncated product method for combining P-values. Genet Epidemiol (2002) 7.07
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med (2001) 6.79
A simple correction for multiple comparisons in interval mapping genome scans. Heredity (Edinb) (2001) 5.98
An efficient Monte Carlo approach to assessing statistical significance in genomic studies. Bioinformatics (2004) 4.90
Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies. Am J Hum Genet (2004) 4.15
Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care (1998) 3.99
Rapid simulation of P values for product methods and multiple-testing adjustment in association studies. Am J Hum Genet (2005) 2.89
A fast method for computing high-significance disease association in large population-based studies. Am J Hum Genet (2006) 2.84
Evaluation of Nyholt's procedure for multiple testing correction. Hum Hered (2005) 2.50
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes (2006) 2.03
An overview of statistical methods for multiple failure time data in clinical trials. Stat Med (1997) 1.97
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes (2007) 1.74
Approximate multinormal probabilities applied to correlated multiple endpoints in clinical trials. Stat Med (1991) 1.33
On rapid stimulation of P values in association studies. Am J Hum Genet (2005) 1.32
Finding the missing heritability of complex diseases. Nature (2009) 67.95
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet (2011) 18.88
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet (2006) 17.36
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Replicating genotype-phenotype associations. Nature (2007) 16.11
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics (2010) 13.54
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature (2003) 12.10
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15
Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med (2014) 6.12
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Low-coverage sequencing: implications for design of complex trait association studies. Genome Res (2011) 5.34
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet (2008) 4.84
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Optimal designs for two-stage genome-wide association studies. Genet Epidemiol (2007) 4.22
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal. Am J Hum Genet (2005) 3.62
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet (2011) 3.56
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci U S A (2009) 3.49
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Ordered subset analysis in genetic linkage mapping of complex traits. Genet Epidemiol (2004) 2.92
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Efficient study designs for test of genetic association using sibship data and unrelated cases and controls. Am J Hum Genet (2006) 2.72
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes (2006) 2.58
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet (2012) 2.55
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes (2004) 2.46
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Assessing whether an allele can account in part for a linkage signal: the Genotype-IBD Sharing Test (GIST). Am J Hum Genet (2004) 2.43
Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes (2004) 2.43
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools. Proc Natl Acad Sci U S A (2002) 2.32
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes (2011) 2.21
Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci. Cell Metab (2010) 2.21
Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells. Am J Hum Genet (2005) 2.20
Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information. Am J Hum Genet (2004) 2.19
Probability of detection of genotyping errors and mutations as inheritance inconsistencies in nuclear-family data. Am J Hum Genet (2002) 2.15
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes (2006) 2.03
Quantifying and correcting for the winner's curse in genetic association studies. Genet Epidemiol (2009) 2.02
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes (2008) 2.01
Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data. Am J Hum Genet (2012) 1.94
Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men. Diabetes (2009) 1.87
General framework for meta-analysis of rare variants in sequencing association studies. Am J Hum Genet (2013) 1.86
Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. PLoS Genet (2011) 1.81
Tissue-specific alternative splicing of TCF7L2. Hum Mol Genet (2009) 1.80
Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men. Diabetes (2012) 1.78
Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies. Genet Epidemiol (2009) 1.76
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes (2007) 1.74
Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genet Epidemiol (2006) 1.74
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants. Hum Mol Genet (2008) 1.65
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet (2009) 1.61
Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol (2009) 1.60
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet (2013) 1.57
Recommended joint and meta-analysis strategies for case-control association testing of single low-count variants. Genet Epidemiol (2013) 1.52
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. PLoS Genet (2013) 1.51
A tobit variance-component method for linkage analysis of censored trait data. Am J Hum Genet (2003) 1.49
Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands. Am J Med Genet (2002) 1.35
X-linked recessive atrophic macular degeneration from RPGR mutation. Genomics (2002) 1.34
Ascertainment-adjusted parameter estimates revisited. Am J Hum Genet (2002) 1.34
Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) (2007) 1.32
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes (2013) 1.25
Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet (2005) 1.18
Quantitative trait linkage analysis using Gaussian copulas. Genetics (2006) 1.18
IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies. Diabetes (2006) 1.18
Pleiotropy analysis of quantitative traits at gene level by multivariate functional linear models. Genet Epidemiol (2015) 1.16
Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known. Genet Epidemiol (2006) 1.16