Published in J Mol Cell Biol on June 01, 2012
An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer. J Am Med Inform Assoc (2012) 1.10
Big biological data: challenges and opportunities. Genomics Proteomics Bioinformatics (2014) 0.79
Investigation of anti-cancer mechanisms by comparative analysis of naked mole rat and rat. BMC Syst Biol (2013) 0.76
Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis. Genome Med (2016) 0.75
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med (2013) 11.10
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol (2011) 5.96
Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study. Lancet (2007) 5.21
European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens (2013) 4.28
Role of detection method in predicting breast cancer survival: analysis of randomized screening trials. J Natl Cancer Inst (2005) 4.01
Extra-embryonic function of Rb is essential for embryonic development and viability. Nature (2003) 3.92
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury. Am J Physiol Renal Physiol (2007) 3.54
Gene transfer into genomes of human cells by the sleeping beauty transposon system. Mol Ther (2003) 3.34
Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens (Greenwich) (2013) 2.94
Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations. J Invest Dermatol (2009) 2.94
Masked hypertension in diabetes mellitus: treatment implications for clinical practice. Hypertension (2013) 2.89
Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension. J Hypertens (2014) 2.82
Is breast cancer survival improving? Cancer (2004) 2.73
Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations. Hypertension (2010) 2.64
Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia. Blood (2014) 2.53
Inferring gene regulatory networks from multiple microarray datasets. Bioinformatics (2006) 2.49
Pax6 is a human neuroectoderm cell fate determinant. Cell Stem Cell (2010) 2.46
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor. Nat Methods (2008) 2.44
European Society of Hypertension International Protocol revision 2010 for the validation of blood pressure measuring devices in adults. Blood Press Monit (2010) 2.42
Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers. Sci Rep (2012) 2.37
Ambulatory blood pressure monitoring in 9357 subjects from 11 populations highlights missed opportunities for cardiovascular prevention in women. Hypertension (2011) 2.33
Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. Clin Cancer Res (2004) 2.28
Prognostic value of isolated nocturnal hypertension on ambulatory measurement in 8711 individuals from 10 populations. J Hypertens (2010) 2.28
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nat Genet (2002) 2.23
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17
Role of health insurance in averting economic hardship in families after acute stroke in China. Stroke (2009) 2.13
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J (2010) 2.13
Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study. Neurology (2012) 2.06
Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol Cell Biol (2004) 2.00
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. J Exp Med (2012) 1.90
Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J Am Chem Soc (2013) 1.90
A cytochrome C oxidase model catalyzes oxygen to water reduction under rate-limiting electron flux. Science (2007) 1.84
DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Mol Cell Biol (2006) 1.80
Response of a KIT-positive extra-abdominal fibromatosis to imatinib mesylate and KIT genetic analysis. J Natl Cancer Inst (2006) 1.80
Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci U S A (2012) 1.80
Essential hypertension. Lancet (2003) 1.79
Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers. J Clin Psychiatry (2010) 1.79
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proc Natl Acad Sci U S A (2003) 1.74
Effects of berberine on glucose metabolism in vitro. Metabolism (2002) 1.74
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev (2010) 1.73
Optical recording of neuronal activity with a genetically-encoded calcium indicator in anesthetized and freely moving mice. Front Neural Circuits (2010) 1.71
Optimization meets systems biology. BMC Syst Biol (2010) 1.66
Meta-analysis of continuous outcomes combining individual patient data and aggregate data. Stat Med (2008) 1.65
The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase. J Thorac Dis (2010) 1.64
Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells. Mol Cell (2012) 1.63
Blood pressure reduction for the secondary prevention of stroke: a Chinese trial and a systematic review of the literature. Hypertens Res (2009) 1.63
The International Database of Ambulatory Blood Pressure in relation to Cardiovascular Outcome (IDACO): protocol and research perspectives. Blood Press Monit (2007) 1.62
Alignment of molecular networks by integer quadratic programming. Bioinformatics (2007) 1.61
A new solar-powered blood pressure measuring device for low-resource settings. Hypertension (2010) 1.61
NOA: a novel Network Ontology Analysis method. Nucleic Acids Res (2011) 1.60
Enhanced radical scavenging activity by antioxidant-functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidants. Free Radic Biol Med (2007) 1.59
European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring. J Hypertens (2014) 1.58
Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell (2007) 1.56
Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells. Hum Mol Genet (2009) 1.54
Prognostic factors and treatment of patients with T-cell non-Hodgkin lymphoma: the M. D. Anderson Cancer Center experience. Cancer (2005) 1.53
Left atrial regional phasic strain, strain rate and velocity by speckle-tracking echocardiography: normal values and effects of aging in a large group of normal subjects. Int J Cardiol (2013) 1.52
Prediction of protein-RNA binding sites by a random forest method with combined features. Bioinformatics (2010) 1.52
Does a change in angiotensin II formation caused by antihypertensive drugs affect the risk of stroke? A meta-analysis of trials according to treatment with potentially different effects on angiotensin II. J Hypertens (2007) 1.51
Outcome-driven thresholds for ambulatory pulse pressure in 9938 participants recruited from 11 populations. Hypertension (2013) 1.50
Risk stratification by 24-hour ambulatory blood pressure and estimated glomerular filtration rate in 5322 subjects from 11 populations. Hypertension (2012) 1.49
Determinants of the ambulatory arterial stiffness index in 7604 subjects from 6 populations. Hypertension (2008) 1.48
Prognostic significance of visit-to-visit systolic blood pressure variability: a meta-analysis of 77,299 patients. J Clin Hypertens (Greenwich) (2015) 1.47
Characterizing the viscoelastic properties of thin hydrogel-based constructs for tissue engineering applications. J R Soc Interface (2005) 1.47
DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. J Biol Chem (2003) 1.47
Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information. Bioinformatics (2011) 1.45
Blood pressure load does not add to ambulatory blood pressure level for cardiovascular risk stratification. Hypertension (2014) 1.44
Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma. J Mol Cell Biol (2012) 1.43
Dyssynchronous pacing triggers endothelial-mesenchymal transition through heterogeneity of mechanical stretch in a canine model. Circ J (2014) 1.41
Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration. Proc Natl Acad Sci U S A (2007) 1.41
Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev (2009) 1.41
Plasma catecholamine release-inhibitory peptide catestatin in patients with essential hypertension. J Cardiovasc Med (Hagerstown) (2011) 1.41
Molecular communication through stochastic synchronization induced by extracellular fluctuations. Phys Rev Lett (2005) 1.40
Berberine stimulates glucose transport through a mechanism distinct from insulin. Metabolism (2007) 1.40
Treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials. Psychopharmacol Bull (2007) 1.40
Reproducibility of the ambulatory arterial stiffness index in hypertensive patients. J Hypertens (2008) 1.40
Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice. Invest Ophthalmol Vis Sci (2004) 1.40
Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting. J Biol Chem (2001) 1.39
Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development. J Biol Chem (2009) 1.39
rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells. Cell Res (2007) 1.39
Uncovering signal transduction networks from high-throughput data by integer linear programming. Nucleic Acids Res (2008) 1.39
Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy. Cytometry A (2014) 1.38
Small changes for works. J Mol Cell Biol (2011) 1.38
Transcriptome analysis of early organogenesis in human embryos. Dev Cell (2010) 1.37
Glycine metabolism in animals and humans: implications for nutrition and health. Amino Acids (2013) 1.36
Bioluminescence imaging to monitor the in vivo distribution of administered mesenchymal stem cells in acute kidney injury. Am J Physiol Renal Physiol (2008) 1.36
Distinct functions of BMP4 during different stages of mouse ES cell neural commitment. Development (2010) 1.36
Polymorphisms of KDR gene are associated with coronary heart disease. J Am Coll Cardiol (2007) 1.35
The public health impact of coccidioidomycosis in Arizona and California. Int J Environ Res Public Health (2011) 1.35
Prognostic value of the morning blood pressure surge in 5645 subjects from 8 populations. Hypertension (2010) 1.35
Early diagnosis of complex diseases by molecular biomarkers, network biomarkers, and dynamical network biomarkers. Med Res Rev (2013) 1.34
Development of the mammalian lymphatic vasculature. J Clin Invest (2014) 1.34
Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4. Cell Res (2010) 1.33
Disease-aging network reveals significant roles of aging genes in connecting genetic diseases. PLoS Comput Biol (2009) 1.32
Gain-of-function mutations in the extracellular domain of KIT are common in canine mast cell tumors. Mol Cancer Res (2008) 1.31
Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis. Circulation (2012) 1.30
Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma. Cancer (2004) 1.30
Discovering functions and revealing mechanisms at molecular level from biological networks. Proteomics (2007) 1.29
FLEXIBLE CULM 1 encoding a cinnamyl-alcohol dehydrogenase controls culm mechanical strength in rice. Plant Mol Biol (2008) 1.29