Published in PLoS One on May 25, 2012
Screening therapeutic EMT blocking agents in a three-dimensional microenvironment. Integr Biol (Camb) (2013) 1.17
Mechanotransduction of fluid stresses governs 3D cell migration. Proc Natl Acad Sci U S A (2014) 1.02
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A (2014) 0.99
Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment. Sci Rep (2014) 0.92
Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform. Small (2015) 0.85
Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning. Acta Biomater (2014) 0.84
Inducing chemotactic and haptotactic cues in microfluidic devices for three-dimensional in vitro assays. Biomicrofluidics (2014) 0.83
Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network. PLoS Comput Biol (2015) 0.81
Fibroblast Migration in 3D is Controlled by Haptotaxis in a Non-muscle Myosin II-Dependent Manner. Ann Biomed Eng (2015) 0.77
Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep (2016) 0.77
Macrophage-secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. Cancer Res (2016) 0.76
Abluminal stimulation of sphingosine 1-phosphate receptors 1 and 3 promotes and stabilizes endothelial sprout formation. Tissue Eng Part A (2014) 0.75
Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting. Sci Rep (2016) 0.75
Vasculature-On-A-Chip for In Vitro Disease Models. Bioengineering (Basel) (2017) 0.75
Microfluidic on-chip biomimicry for 3D cell culture: a fit-for-purpose investigation from the end user standpoint. Future Sci OA (2017) 0.75
Angiogenesis as a therapeutic target. Nature (2005) 11.89
Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov (2007) 11.46
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol (2009) 5.55
Microfluidic culture platform for neuroscience research. Nat Protoc (2006) 4.02
Continuous and discrete mathematical models of tumor-induced angiogenesis. Bull Math Biol (1998) 3.65
Angiogenesis assays: a critical overview. Clin Chem (2003) 3.32
Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res (2002) 2.96
Cell migration into scaffolds under co-culture conditions in a microfluidic platform. Lab Chip (2008) 2.70
Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging. Lab Chip (2008) 2.34
Cell population tracking and lineage construction with spatiotemporal context. Med Image Anal (2008) 2.26
Fundamentals of microfluidic cell culture in controlled microenvironments. Chem Soc Rev (2010) 2.04
Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices. Blood (2009) 2.04
Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. Biochem Biophys Res Commun (1999) 1.90
Perfused multiwell plate for 3D liver tissue engineering. Lab Chip (2009) 1.88
Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes. Tissue Eng (2006) 1.86
Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip (2005) 1.86
PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors. J Cell Biol (1994) 1.85
Endothelial cell polarization and chemotaxis in a microfluidic device. Lab Chip (2008) 1.83
Engineering microscale cellular niches for three-dimensional multicellular co-cultures. Lab Chip (2009) 1.77
VEGF and endothelial guidance in angiogenic sprouting. Organogenesis (2008) 1.63
Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation. Blood (2006) 1.62
Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation. J Theor Biol (2007) 1.60
Transport-mediated angiogenesis in 3D epithelial coculture. FASEB J (2009) 1.58
Endothelial cell migration in stable gradients of vascular endothelial growth factor A and fibroblast growth factor 2: effects on chemotaxis and chemokinesis. J Biol Chem (2008) 1.58
Mathematical modeling of tumor-induced angiogenesis. Annu Rev Biomed Eng (2006) 1.56
Mathematical modeling of tumor-induced angiogenesis. J Math Biol (2004) 1.51
Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing. Am J Physiol Cell Physiol (2000) 1.42
A high-throughput microfluidic assay to study neurite response to growth factor gradients. Lab Chip (2010) 1.33
A microfluidic chamber for analysis of neuron-to-cell spread and axonal transport of an alpha-herpesvirus. PLoS One (2008) 1.31
Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients. Lab Chip (2010) 1.25
Microfluidic culture models of tumor angiogenesis. Tissue Eng Part A (2010) 1.23
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. Mol Cancer (2006) 1.22
Surface-treatment-induced three-dimensional capillary morphogenesis in a microfluidic platform. Adv Mater (2009) 1.17
Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model. J Theor Biol (2005) 1.16
A multichamber fluidic device for 3D cultures under interstitial flow with live imaging: development, characterization, and applications. Biotechnol Bioeng (2010) 1.01
Multiplexed, high-throughput analysis of 3D microtissue suspensions. Integr Biol (Camb) (2010) 0.99
Platelet factor 4: a chemokine enigma. Int J Biochem Cell Biol (2005) 0.98
Locomotion and proliferation of glioblastoma cells in vitro: statistical evaluation of videomicroscopic observations. J Neurosurg (2000) 0.97
A hybrid continuum-discrete modelling approach to predict and control angiogenesis: analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology. Philos Trans A Math Phys Eng Sci (2010) 0.91
Large-scale analysis of neurite growth dynamics on micropatterned substrates. Integr Biol (Camb) (2010) 0.88
An ex-vivo angiogenesis assay as a screening method for natural compounds and herbal drug preparations. Planta Med (2004) 0.77
Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. Proc Natl Acad Sci U S A (2006) 7.48
Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. J Clin Invest (2004) 5.68
Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc Natl Acad Sci U S A (2004) 4.31
Injectable self-assembling peptide nanofibers create intramyocardial microenvironments for endothelial cells. Circulation (2005) 2.89
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A (2006) 2.75
Cell migration into scaffolds under co-culture conditions in a microfluidic platform. Lab Chip (2008) 2.70
Mechanotransduction through growth-factor shedding into the extracellular space. Nature (2004) 2.48
Cell mechanics and mechanotransduction: pathways, probes, and physiology. Am J Physiol Cell Physiol (2004) 2.32
Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc Natl Acad Sci U S A (2012) 2.29
Endothelial cells promote cardiac myocyte survival and spatial reorganization: implications for cardiac regeneration. Circulation (2004) 2.11
Computational model for cell migration in three-dimensional matrices. Biophys J (2005) 2.09
Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels. Nat Protoc (2012) 1.89
Interstitial flow influences direction of tumor cell migration through competing mechanisms. Proc Natl Acad Sci U S A (2011) 1.81
Biomechanics: cell research and applications for the next decade. Ann Biomed Eng (2009) 1.81
Force-induced activation of talin and its possible role in focal adhesion mechanotransduction. J Biomech (2007) 1.69
Measuring molecular rupture forces between single actin filaments and actin-binding proteins. Proc Natl Acad Sci U S A (2008) 1.59
Transport-mediated angiogenesis in 3D epithelial coculture. FASEB J (2009) 1.58
Wearable Conductive Fiber Sensors for Multi-Axis Human Joint Angle Measurements. J Neuroeng Rehabil (2005) 1.58
Control of self-assembling oligopeptide matrix formation through systematic variation of amino acid sequence. Biomaterials (2002) 1.52
Kinetic control of dimer structure formation in amyloid fibrillogenesis. Proc Natl Acad Sci U S A (2004) 1.52
Computational modeling of cardiovascular response to orthostatic stress. J Appl Physiol (1985) (2002) 1.52
Microfluidic platforms for studies of angiogenesis, cell migration, and cell-cell interactions. Sixth International Bio-Fluid Mechanics Symposium and Workshop March 28-30, 2008 Pasadena, California. Ann Biomed Eng (2010) 1.49
Mechanical deformation of neutrophils into narrow channels induces pseudopod projection and changes in biomechanical properties. J Appl Physiol (1985) (2005) 1.42
A three-dimensional viscoelastic model for cell deformation with experimental verification. Biophys J (2003) 1.42
Mechanotransduction in cardiac myocytes. Ann N Y Acad Sci (2004) 1.40
Utility of the photoplethysmogram in circulatory monitoring. Anesthesiology (2008) 1.39
A high-throughput microfluidic assay to study neurite response to growth factor gradients. Lab Chip (2010) 1.33
Self-assembling short oligopeptides and the promotion of angiogenesis. Biomaterials (2005) 1.33
Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments. Biomicrofluidics (2011) 1.29
Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab Chip (2012) 1.28
Microfluidic models of vascular functions. Annu Rev Biomed Eng (2012) 1.25
In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients. Lab Chip (2011) 1.24
Cuffless blood pressure monitoring using hydrostatic pressure changes. IEEE Trans Biomed Eng (2008) 1.21
Computational analysis of viscoelastic properties of crosslinked actin networks. PLoS Comput Biol (2009) 1.20
Mechanisms of tumor cell extravasation in an in vitro microvascular network platform. Integr Biol (Camb) (2013) 1.19
Cellular fluid mechanics and mechanotransduction. Ann Biomed Eng (2005) 1.18
Screening therapeutic EMT blocking agents in a three-dimensional microenvironment. Integr Biol (Camb) (2013) 1.17
Surface-treatment-induced three-dimensional capillary morphogenesis in a microfluidic platform. Adv Mater (2009) 1.17
Tumor cell migration in complex microenvironments. Cell Mol Life Sci (2012) 1.16
In vitro model of tumor cell extravasation. PLoS One (2013) 1.16
Autocrine EGF receptor activation mediates endothelial cell migration and vascular morphogenesis induced by VEGF under interstitial flow. Exp Cell Res (2005) 1.15
Stress transmission in the lung: pathways from organ to molecule. Annu Rev Physiol (2006) 1.15
Three-dimensional cellular deformation analysis with a two-photon magnetic manipulator workstation. Biophys J (2002) 1.12
A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment. Lab Chip (2012) 1.12
VASP involvement in force-mediated adherens junction strengthening. Biochem Biophys Res Commun (2008) 1.09
Sprouting angiogenesis under a chemical gradient regulated by interactions with an endothelial monolayer in a microfluidic platform. Anal Chem (2011) 1.08
Effects of systematic variation of amino acid sequence on the mechanical properties of a self-assembling, oligopeptide biomaterial. J Biomater Sci Polym Ed (2002) 1.05
Engineering of in vitro 3D capillary beds by self-directed angiogenic sprouting. PLoS One (2012) 1.04
Biomechanical Regulation of Endothelium-dependent Events Critical for Adaptive Remodeling. J Biol Chem (2008) 1.03
Atomistic simulation approach to a continuum description of self-assembled beta-sheet filaments. Biophys J (2006) 1.03
Mechanotransduction of fluid stresses governs 3D cell migration. Proc Natl Acad Sci U S A (2014) 1.02
Cytoskeletal remodeling and cellular activation during deformation of neutrophils into narrow channels. J Appl Physiol (1985) (2005) 1.02
Neutrophil transit times through pulmonary capillaries: the effects of capillary geometry and fMLP-stimulation. Biophys J (2002) 1.01
Nuclear mechanics and methods. Methods Cell Biol (2007) 1.01
Mechanism of a flow-gated angiogenesis switch: early signaling events at cell-matrix and cell-cell junctions. Integr Biol (Camb) (2012) 1.00
Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells. Stem Cell Rev (2015) 0.98
Dynamic modeling of cell migration and spreading behaviors on fibronectin coated planar substrates and micropatterned geometries. PLoS Comput Biol (2013) 0.98
Three-dimensional extracellular matrix-mediated neural stem cell differentiation in a microfluidic device. Lab Chip (2012) 0.97
Microfluidic platforms for mechanobiology. Lab Chip (2013) 0.97
Differentiation of embryonic stem cells into cardiomyocytes in a compliant microfluidic system. Ann Biomed Eng (2011) 0.97
Mechanical analysis of atherosclerotic plaques based on optical coherence tomography. Ann Biomed Eng (2004) 0.95
Dynamic mechanisms of cell rigidity sensing: insights from a computational model of actomyosin networks. PLoS One (2012) 0.95
3D matrix microenvironment for targeted differentiation of embryonic stem cells into neural and glial lineages. Biomaterials (2013) 0.94
Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems. Integr Biol (Camb) (2014) 0.93
Molecular Biomechanics: The Molecular Basis of How Forces Regulate Cellular Function. Mol Cell Biomech (2010) 0.91
A hybrid continuum-discrete modelling approach to predict and control angiogenesis: analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology. Philos Trans A Math Phys Eng Sci (2010) 0.91
A microfluidic platform for studying the effects of small temperature gradients in an incubator environment. Biomicrofluidics (2008) 0.91
Hot embossing for fabrication of a microfluidic 3D cell culture platform. Biomed Microdevices (2011) 0.91
A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment. Biomed Microdevices (2010) 0.90
Fast fluorescence laser tracking microrheometry, II: quantitative studies of cytoskeletal mechanotransduction. Biophys J (2008) 0.90
Synergistic effects of tethered growth factors and adhesion ligands on DNA synthesis and function of primary hepatocytes cultured on soft synthetic hydrogels. Biomaterials (2010) 0.90
Modular aspects of kinesin force generation machinery. Biophys J (2013) 0.90
Fast fluorescence laser tracking microrheometry. I: instrument development. Biophys J (2007) 0.90
Control of perfusable microvascular network morphology using a multiculture microfluidic system. Tissue Eng Part C Methods (2013) 0.89
Extracellular matrix heterogeneity regulates three-dimensional morphologies of breast adenocarcinoma cell invasion. Adv Healthc Mater (2012) 0.89
Wearable, cuff-less PPG-based blood pressure monitor with novel height sensor. Conf Proc IEEE Eng Med Biol Soc (2006) 0.88
Contrasting effects of vasculogenic induction upon biaxial bioreactor stimulation of mesenchymal stem cells and endothelial progenitor cells cocultures in three-dimensional scaffolds under in vitro and in vivo paradigms for vascularized bone tissue engineering. Tissue Eng Part A (2012) 0.87
Macromolecular crowding amplifies adipogenesis of human bone marrow-derived mesenchymal stem cells by enhancing the pro-adipogenic microenvironment. Tissue Eng Part A (2013) 0.87
Dynamic role of cross-linking proteins in actin rheology. Biophys J (2011) 0.86
Integrating focal adhesion dynamics, cytoskeleton remodeling, and actin motor activity for predicting cell migration on 3D curved surfaces of the extracellular matrix. Integr Biol (Camb) (2012) 0.86
Endothelial nitric oxide production during in vitro simulation of external limb compression. Am J Physiol Heart Circ Physiol (2002) 0.86
Utilization and control of bioactuators across multiple length scales. Lab Chip (2014) 0.86
ROS1 signaling regulates epithelial differentiation in the epididymis. Endocrinology (2014) 0.85
Microfluidic chemotaxis platform for differentiating the roles of soluble and bound amyloid-β on microglial accumulation. Sci Rep (2013) 0.85