Published in PLoS One on May 30, 2012
Can exercise teach us how to treat heart disease? Circulation (2012) 1.70
Exercise dose, exercise adherence, and associated health outcomes in the TIGER study. Med Sci Sports Exerc (2014) 1.49
Exercise for obese youth: refocusing attention from weight loss to health gains. Exerc Sport Sci Rev (2015) 1.40
Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained. J Physiol (2016) 1.07
Heritability of objectively assessed daily physical activity and sedentary behavior. Am J Clin Nutr (2013) 1.02
VO2max trainability and high intensity interval training in humans: a meta-analysis. PLoS One (2013) 1.01
The association between leisure time physical activity and coronary heart disease among men with different physical work demands: a prospective cohort study. Eur J Epidemiol (2013) 0.98
Toward exercise as personalized medicine. Sports Med (2013) 0.96
Genetic influence on exercise-induced changes in physical function among mobility-limited older adults. Physiol Genomics (2014) 0.95
Aerobic exercise but not resistance exercise reduces intrahepatic lipid content and visceral fat and improves insulin sensitivity in obese adolescent girls: a randomized controlled trial. Am J Physiol Endocrinol Metab (2013) 0.94
Heterogeneity of physical function responses to exercise training in older adults. J Am Geriatr Soc (2015) 0.93
Type 2 diabetes mellitus and exercise impairment. Rev Endocr Metab Disord (2013) 0.93
Advances in exercise, fitness, and performance genomics in 2012. Med Sci Sports Exerc (2013) 0.93
Pancreatic β-cell function is a stronger predictor of changes in glycemic control after an aerobic exercise intervention than insulin sensitivity. J Clin Endocrinol Metab (2013) 0.91
Genetic determinants of voluntary exercise. Trends Genet (2013) 0.90
Selectively bred rat model system for low and high response to exercise training. Physiol Genomics (2013) 0.90
You can't teach speed: sprinters falsify the deliberate practice model of expertise. PeerJ (2014) 0.89
Insulin sensitivity and metabolic flexibility following exercise training among different obese insulin-resistant phenotypes. Am J Physiol Endocrinol Metab (2013) 0.89
The independent and combined effects of exercise training and reducing sedentary behavior on cardiometabolic risk factors. Appl Physiol Nutr Metab (2014) 0.88
The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training. Int J Physiol Pathophysiol Pharmacol (2014) 0.85
Genomic and transcriptomic predictors of response levels to endurance exercise training. J Physiol (2016) 0.85
Healthy obese persons: how can they be identified and do metabolic profiles stratify risk? Curr Opin Endocrinol Diabetes Obes (2013) 0.84
Using response variation to develop more effective, personalized behavioral medicine?: evidence from the Resist Diabetes study. Transl Behav Med (2014) 0.83
Personalized metabolomics for predicting glucose tolerance changes in sedentary women after high-intensity interval training. Sci Rep (2014) 0.82
Are there negative responders to exercise training among heart failure patients? Med Sci Sports Exerc (2014) 0.82
Understanding the individual responsiveness to resistance training periodization. Age (Dordr) (2015) 0.79
A transcriptional signature of "exercise resistance" in skeletal muscle of individuals with type 2 diabetes mellitus. Metabolism (2015) 0.79
Dietary composition regulates Drosophila mobility and cardiac physiology. J Exp Biol (2012) 0.79
Physical activity enhances metabolic fitness independently of cardiorespiratory fitness in marathon runners. Dis Markers (2015) 0.79
Exercise for Hypertension: A Prescription Update Integrating Existing Recommendations with Emerging Research. Curr Hypertens Rep (2015) 0.79
The effects of exercise on the lipoprotein subclass profile: A meta-analysis of 10 interventions. Atherosclerosis (2015) 0.79
The relationship between the blood pressure responses to exercise following training and detraining periods. PLoS One (2014) 0.78
Exercise and diabetes: relevance and causes for response variability. Endocrine (2015) 0.77
Genotype by energy expenditure interaction with metabolic syndrome traits: the Portuguese healthy family study. PLoS One (2013) 0.77
Effect of adiposity on insulin action after acute and chronic resistance exercise in non-diabetic women. Eur J Appl Physiol (2013) 0.77
Transient increase in homocysteine but not hyperhomocysteinemia during acute exercise at different intensities in sedentary individuals. PLoS One (2012) 0.76
The prevalence of adverse cardiometabolic responses to exercise training with evidence-based practice is low. Diabetes Metab Syndr Obes (2015) 0.76
Safety and efficacy of aerobic training in patients with cancer who have heart failure: an analysis of the HF-ACTION randomized trial. J Clin Oncol (2014) 0.76
Skeletal Muscle PGC1α -1 Nucleosome Position and -260nt DNA Methylation Determine Exercise Response and Prevent Ectopic Lipid Accumulation in Men. Endocrinology (2017) 0.76
Is Physical Fitness Associated with Health in Overweight and Obese Youth? A Systematic Review. Kinesiol Rev (Champaign) (2013) 0.75
Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews. Cochrane Database Syst Rev (2017) 0.75
And what about exercise? Fitness and risk of death in "low-risk" adults. J Am Heart Assoc (2012) 0.75
Adverse Cardiovascular Response to Aerobic Exercise Training: Is This a Concern? Med Sci Sports Exerc (2016) 0.75
Circulating MiRNAs as biomarkers of gait speed responses to aerobic exercise training in obese older adults. Aging (Albany NY) (2017) 0.75
Inter-Individual Variability in the Adaptive Responses to Endurance and Sprint Interval Training: A Randomized Crossover Study. PLoS One (2016) 0.75
Genomic and transcriptomic predictors of triglyceride response to regular exercise. Br J Sports Med (2015) 0.75
Deep-targeted exon sequencing reveals renal polymorphisms associate with postexercise hypotension among African Americans. Physiol Rep (2016) 0.75
Pyruvate Dehydrogenase Phosphatase Regulatory Gene Expression Correlates with Exercise Training Insulin Sensitivity Changes. Med Sci Sports Exerc (2016) 0.75
Consequences of objective self-awareness during exercise. Health Psychol Open (2015) 0.75
Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes. Diabetes Obes Metab (2016) 0.75
Is Home-Based, High-Intensity Interval Training Cycling Feasible and Safe for Patients With Knee Osteoarthritis?: Study Protocol for a Randomized Pilot Study. Orthop J Sports Med (2017) 0.75
Effects of 6-Weeks High-Intensity Interval Training in Schoolchildren with Insulin Resistance: Influence of Biological Maturation on Metabolic, Body Composition, Cardiovascular and Performance Non-responses. Front Physiol (2017) 0.75
Inter-Individual Responses of Maximal Oxygen Uptake to Exercise Training: A Critical Review. Sports Med (2017) 0.75
A Practical and Time-Efficient High-Intensity Interval Training Program Modifies Cardio-Metabolic Risk Factors in Adults with Risk Factors for Type II Diabetes. Front Endocrinol (Lausanne) (2017) 0.75
Cardiac arrest during long-distance running races. N Engl J Med (2012) 3.34
Individual differences in response to regular physical activity. Med Sci Sports Exerc (2001) 2.96
Familial aggregation of VO(2max) response to exercise training: results from the HERITAGE Family Study. J Appl Physiol (1985) (1999) 2.89
The incidence of primary cardiac arrest during vigorous exercise. N Engl J Med (1984) 2.80
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. J Appl Physiol (1985) (2010) 2.43
Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted Risk Reduction Intervention Through Defined Exercise - STRRIDE-AT/RT). Am J Cardiol (2011) 2.28
Effects of exercise training on glucose homeostasis: the HERITAGE Family Study. Diabetes Care (2005) 1.96
Dose Response to Exercise in Women aged 45-75 yr (DREW): design and rationale. Med Sci Sports Exerc (2004) 1.92
Studies of a targeted risk reduction intervention through defined exercise (STRRIDE). Med Sci Sports Exerc (2001) 1.84
The HERITAGE family study. Aims, design, and measurement protocol. Med Sci Sports Exerc (1995) 1.83
The human gene map for performance and health-related fitness phenotypes: the 2001 update. Med Sci Sports Exerc (2002) 1.18
Individual responses to combined endurance and strength training in older adults. Med Sci Sports Exerc (2011) 1.15
Reproducibility of maximal exercise test data in the HERITAGE family study. Med Sci Sports Exerc (1999) 1.14
Plasma post-heparin lipase activities in the HERITAGE Family Study: the reproducibility, gender differences, and associations with lipoprotein levels. HEalth, RIsk factors, exercise Training and GEnetics. Clin Biochem (1999) 1.04
Inflammation and exercise (INFLAME): study rationale, design, and methods. Contemp Clin Trials (2007) 1.03
Heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs. J Appl Physiol (1985) (2011) 1.00
Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study. Diabetologia (2005) 0.99
Familial resemblance for coronary heart disease risk: the HERITAGE Family Study. Ethn Dis (2000) 0.98
Heritability of HR and BP response to exercise training in the HERITAGE Family Study. Med Sci Sports Exerc (2002) 0.98
Familial aggregation of blood lipid response to exercise training in the health, risk factors, exercise training, and genetics (HERITAGE) Family Study. Circulation (2002) 0.95
Reproducibility of cardiovascular, respiratory, and metabolic responses to submaximal exercise: the HERITAGE Family Study. Med Sci Sports Exerc (1998) 0.93
The effect of endurance exercise training on plasma lipoprotein AI and lipoprotein AI:AII concentrations in sedentary adults. Metabolism (2002) 0.91
Variability in the response of HDL cholesterol to exercise training in the HERITAGE Family Study. Int J Sports Med (2002) 0.91
The HERITAGE Family Study: quality assurance and quality control. Ann Epidemiol (1996) 0.88
Reproducibility of anthropometric and body composition measurements: the HERITAGE Family Study. Int J Obes Relat Metab Disord (1997) 0.87
Athletes, athletics, and sudden cardiac death. Med Sci Sports Exerc (1993) 0.85
Exercise and sudden cardiac death: protection or provocation. N Engl J Med (1984) 0.84
Familiality of triglyceride and LPL response to exercise training: the HERITAGE study. Med Sci Sports Exerc (2000) 0.81
Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet (2012) 20.56
Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc (2007) 20.11
Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation (2007) 18.32
2011 Compendium of Physical Activities: a second update of codes and MET values. Med Sci Sports Exerc (2011) 13.10
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc (2009) 8.89
Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc (2007) 8.67
Sitting time and mortality from all causes, cardiovascular disease, and cancer. Med Sci Sports Exerc (2009) 8.16
AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulation (2006) 8.01
Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Circulation (2007) 7.61
A mapping function for man. Hum Hered (1977) 7.50
Effects of the amount and intensity of exercise on plasma lipoproteins. N Engl J Med (2002) 7.34
Cardiorespiratory fitness and adiposity as mortality predictors in older adults. JAMA (2007) 7.26
Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61
Analysis of family resemblance. II. A linear model for familial correlation. Am J Hum Genet (1974) 6.51
Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA (2009) 6.36
American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc (2009) 6.07
A unified model for complex segregation analysis. Am J Hum Genet (1983) 5.67
Association of coffee consumption with all-cause and cardiovascular disease mortality. Mayo Clin Proc (2013) 5.27
Effects of aerobic and resistance training on hemoglobin A1c levels in patients with type 2 diabetes: a randomized controlled trial. JAMA (2010) 4.74
A maximum likelihood map of chromosome 1. Am J Hum Genet (1979) 4.34
Trends over 5 decades in U.S. occupation-related physical activity and their associations with obesity. PLoS One (2011) 4.21
Physical activity and stroke risk: a meta-analysis. Stroke (2003) 4.19
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care (2009) 3.69
Interventions to promote physical activity and dietary lifestyle changes for cardiovascular risk factor reduction in adults: a scientific statement from the American Heart Association. Circulation (2010) 3.63
Is it time to change the way we report and discuss weight loss? Obesity (Silver Spring) (2009) 3.57
Objective measurement of levels and patterns of physical activity. Arch Dis Child (2007) 3.48
Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes. Arch Intern Med (2005) 3.34
Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale. Am Heart J (2007) 3.34
Association between muscular strength and mortality in men: prospective cohort study. BMJ (2008) 3.33
Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE--a randomized controlled study. Arch Intern Med (2004) 3.30
Visceral fat is an independent predictor of all-cause mortality in men. Obesity (Silver Spring) (2006) 3.29
Cardiorespiratory fitness is inversely associated with the incidence of metabolic syndrome: a prospective study of men and women. Circulation (2005) 3.27
The transmission of schizophrenia under a multifactorial threshold model. Am J Hum Genet (1983) 3.24
NHLBI Family Heart Study: objectives and design. Am J Epidemiol (1996) 3.21
Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol (1985) (2003) 3.18
Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Ann Intern Med (2010) 3.17
Objectively measured physical activity and fat mass in a large cohort of children. PLoS Med (2007) 3.14
Sedentary behaviors increase risk of cardiovascular disease mortality in men. Med Sci Sports Exerc (2010) 3.06
Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial. Ann Intern Med (2004) 3.05
Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: the Swedish Obese Subjects, the HERITAGE Family Study, and a Memphis cohort. J Clin Endocrinol Metab (2002) 3.04
The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness. Eur Heart J (2012) 3.02
Race, visceral adipose tissue, plasma lipids, and lipoprotein lipase activity in men and women: the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) family study. Arterioscler Thromb Vasc Biol (2000) 3.01
Exercise capacity and body composition as predictors of mortality among men with diabetes. Diabetes Care (2004) 2.97
Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation (2012) 2.95
The effect of sex, age and race on estimating percentage body fat from body mass index: The Heritage Family Study. Int J Obes Relat Metab Disord (2002) 2.95
How many steps/day are enough? For adults. Int J Behav Nutr Phys Act (2011) 2.92
Familial aggregation of VO(2max) response to exercise training: results from the HERITAGE Family Study. J Appl Physiol (1985) (1999) 2.89
Effects of a 16-month randomized controlled exercise trial on body weight and composition in young, overweight men and women: the Midwest Exercise Trial. Arch Intern Med (2003) 2.83
Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA (2009) 2.83
The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods. Contemp Clin Trials (2005) 2.79
Genome-wide linkage analysis of systolic and diastolic blood pressure: the Québec Family Study. Circulation (2000) 2.75
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study. Eur Heart J (2005) 2.69
Methods for handling multiple testing. Adv Genet (2008) 2.67
How many steps/day are enough? For older adults and special populations. Int J Behav Nutr Phys Act (2011) 2.62
Cardiorespiratory fitness levels among US adults 20-49 years of age: findings from the 1999-2004 National Health and Nutrition Examination Survey. Am J Epidemiol (2010) 2.60
Validity of U.S. nutritional surveillance:National Health and Nutrition Examination Survey caloric energy intake data, 1971-2010. PLoS One (2013) 2.58
AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update endorsed by the National Heart, Lung, and Blood Institute. J Am Coll Cardiol (2006) 2.57
A prospective study of fitness, fatness, and depressive symptoms. Am J Epidemiol (2015) 2.52
Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivors. J Clin Oncol (2007) 2.50
Weight bias among health professionals specializing in obesity. Obes Res (2003) 2.44
Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. J Appl Physiol (1985) (2010) 2.43
Calibration of an accelerometer during free-living activities in children. Int J Pediatr Obes (2007) 2.41
Dietary patterns and the risk of mortality: impact of cardiorespiratory fitness. Int J Epidemiol (2009) 2.38
Inactivity, exercise, and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol (1985) (2005) 2.38
Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Network study. Hypertension (2004) 2.36
Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet (2006) 2.34
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet (2010) 2.34
The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med Sci Sports Exerc (2009) 2.30
Factors related to morbidity and mortality in patients with chronic heart failure with systolic dysfunction: the HF-ACTION predictive risk score model. Circ Heart Fail (2011) 2.28