Published in BMC Res Notes on June 13, 2012
Gene expression dynamics during diabetic periodontitis. J Dent Res (2012) 0.78
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res (2002) 40.03
The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol (1996) 22.30
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature (2009) 19.65
Analysis of variance for gene expression microarray data. J Comput Biol (2000) 16.28
Microarray data normalization and transformation. Nat Genet (2002) 15.04
Using GOstats to test gene lists for GO term association. Bioinformatics (2006) 12.58
Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett (2004) 11.00
Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol (2006) 7.93
RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics (2006) 6.50
Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med (1991) 4.43
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med (1998) 4.17
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. Proc Natl Acad Sci U S A (1997) 3.88
Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med (1993) 3.31
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data. BMC Bioinformatics (2006) 3.31
The use and analysis of microarray data. Nat Rev Drug Discov (2002) 3.08
Thalidomide: dermatological indications, mechanisms of action and side-effects. Br J Dermatol (2005) 2.46
Transcriptional profiling of the LPS induced NF-kappaB response in macrophages. BMC Immunol (2007) 1.71
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Res (2009) 1.68
Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation. J Infect Dis (2005) 1.64
Mechanism and its regulation of tumor-induced angiogenesis. World J Gastroenterol (2003) 1.55
Protein tyrosine phosphatases as adhesion receptors. Curr Opin Cell Biol (1995) 1.44
Properties of thalidomide and its analogues: implications for anticancer therapy. AAPS J (2005) 1.33
Antitumor effects of thalidomide analogs in human prostate cancer xenografts implanted in immunodeficient mice. Clin Cancer Res (2004) 1.25
Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression. Innate Immun (2009) 1.10
Thalidomide suppresses NF-kappa B activation induced by TNF and H2O2, but not that activated by ceramide, lipopolysaccharides, or phorbol ester. J Immunol (2002) 1.05
Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis (2010) 1.00
Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide. J Infect (2009) 0.96
Pentraxins in humoral innate immunity. Adv Exp Med Biol (2012) 0.87
Applications of microarrays in the pharmaceutical industry. Curr Opin Pharmacol (2002) 0.85
Thalidomide: from tragedy to promise. Swiss Med Wkly (2003) 0.85
Gene expression data analysis. Microbes Infect (2001) 0.84
Anti-angiogenic effects of thalidomide: expression of apoptosis-inducible active-caspase-3 in a three-dimensional collagen gel culture of aorta. Histochem Cell Biol (2004) 0.83
FTH1 binds to Daxx and inhibits Daxx-mediated cell apoptosis. Mol Biol Rep (2011) 0.83
s-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line. Hematol J (2004) 0.82
Polymorphism of microsomal epoxide hydrolase is associated with chronic obstructive pulmonary disease and bronchodilator response. J Formos Med Assoc (2011) 0.81
Effects of thalidomide on intracellular Mycobacterium leprae in normal and activated macrophages. Clin Diagn Lab Immunol (2005) 0.77
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood (2011) 4.21
Susceptibility to leprosy is associated with PARK2 and PACRG. Nature (2004) 3.07
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia. Blood (2009) 3.00
Adult-onset immunodeficiency in Thailand and Taiwan. N Engl J Med (2012) 2.87
Cohort study of molecular identification and typing of Mycobacterium abscessus, Mycobacterium massiliense, and Mycobacterium bolletii. J Clin Microbiol (2009) 2.58
Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science (2013) 2.34
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nat Med (2003) 2.08
Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis. J Leukoc Biol (2009) 1.89
Inhaled amikacin for treatment of refractory pulmonary nontuberculous mycobacterial disease. Ann Am Thorac Soc (2014) 1.76
Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science (2003) 1.73
Anti-CD20 (rituximab) therapy for anti-IFN-γ autoantibody-associated nontuberculous mycobacterial infection. Blood (2012) 1.68
Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia. Blood (2010) 1.56
Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe (2009) 1.55
Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. J Allergy Clin Immunol (2013) 1.49
Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis. Infect Immun (2002) 1.48
MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nat Med (2012) 1.43
New rapid scheme for distinguishing the subspecies of the Mycobacterium abscessus group and identifying Mycobacterium massiliense isolates with inducible clarithromycin resistance. J Clin Microbiol (2013) 1.43
Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection. Infect Immun (2005) 1.29
Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy. J Immunol (2005) 1.24
High-level relatedness among Mycobacterium abscessus subsp. massiliense strains from widely separated outbreaks. Emerg Infect Dis (2014) 1.21
Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy. Infect Immun (2003) 1.18
T-cell responses to the Mycobacterium tuberculosis-specific antigen ESAT-6 in Brazilian tuberculosis patients. Infect Immun (2002) 1.15
NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med (2012) 1.14
Evaluation of real-time and conventional PCR targeting complex 85 genes for detection of Mycobacterium leprae DNA in skin biopsy samples from patients diagnosed with leprosy. J Clin Microbiol (2006) 1.09
Rational combination of peptides derived from different Mycobacterium leprae proteins improves sensitivity for immunodiagnosis of M. leprae infection. Clin Vaccine Immunol (2008) 1.08
Role of tumor necrosis factor-alpha and interleukin-10 promoter gene polymorphisms in leprosy. J Infect Dis (2002) 1.08
Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes. Cell Microbiol (2010) 1.07
Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation. J Biol Chem (2010) 1.04
TLR6-driven lipid droplets in Mycobacterium leprae-infected Schwann cells: immunoinflammatory platforms associated with bacterial persistence. J Immunol (2011) 1.03
Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis (2010) 1.00
Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania. FASEB J (2009) 1.00
Adaptability and persistence of the emerging pathogen Bordetella petrii. PLoS One (2013) 0.97
NF-kappaB-mediated repression of iNOS expression in Leishmania amazonensis macrophage infection. Immunol Lett (2009) 0.96
Clinical and therapeutic features of pulmonary nontuberculous mycobacterial disease, Brazil, 1993-2011. Emerg Infect Dis (2013) 0.94
Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment. Cell Microbiol (2014) 0.93
Interleukin-10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population. Immunogenetics (2003) 0.93
Impact of PGL-I seropositivity on the protective effect of BCG vaccination among leprosy contacts: a cohort study. PLoS Negl Trop Dis (2012) 0.93
IFNG +874T/A polymorphism is not associated with American tegumentary leishmaniasis susceptibility but can influence Leishmania induced IFN-gamma production. BMC Infect Dis (2007) 0.93
Leprosy among patient contacts: a multilevel study of risk factors. PLoS Negl Trop Dis (2011) 0.92
Criteria for diagnosis of pure neural leprosy. J Neurol (2003) 0.90
Genomic insights into the emerging human pathogen Mycobacterium massiliense. J Bacteriol (2012) 0.90
Role of PGL-I antibody detection in the diagnosis of pure neural leprosy. Lepr Rev (2005) 0.90
Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease. Infect Immun (2009) 0.90
CD163 favors Mycobacterium leprae survival and persistence by promoting anti-inflammatory pathways in lepromatous macrophages. Eur J Immunol (2012) 0.90
Draft Genome Sequences of Burkholderia cenocepacia ET12 Lineage Strains K56-2 and BC7. Genome Announc (2013) 0.89
Kinetics of T cell-activation molecules in response to Mycobacterium tuberculosis antigens. Mem Inst Oswaldo Cruz (2003) 0.89
Differential TNFalpha mRNA regulation detected in the epidermis of leprosy patients. Arch Dermatol Res (2002) 0.88
TNF -308G>A single nucleotide polymorphism is associated with leprosy among Brazilians: a genetic epidemiology assessment, meta-analysis, and functional study. J Infect Dis (2011) 0.87
Lipid body mobilization in the ExoU-induced release of inflammatory mediators by airway epithelial cells. Microb Pathog (2008) 0.87
The T-cell anergy induced by Leishmania amazonensis antigens is related with defective antigen presentation and apoptosis. An Acad Bras Cienc (2004) 0.87
Expression of metalloproteinases (MMP-2, MMP-9, and TACE) and TNF-alpha in the nerves of leprosy patients. J Peripher Nerv Syst (2007) 0.87
Neurite outgrowth is impaired on HSP70-positive astrocytes through a mechanism that requires NF-kappaB activation. Brain Res (2002) 0.87
Caspase-8 activity prevents type 2 cytokine responses and is required for protective T cell-mediated immunity against Trypanosoma cruzi infection. J Immunol (2005) 0.87
High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions. Infect Immun (2009) 0.86
Epidemiological and clinical patterns of 92 patients co-infected with HIV and Mycobacterium leprae from Rio de Janeiro State, Brazil. Trans R Soc Trop Med Hyg (2013) 0.85
A profile of patients treated at a national leprosy outpatient referral clinic in Rio de Janeiro, Brazil, 1986-2007. Rev Panam Salud Publica (2012) 0.84
Another round for the CD4+CD25+ regulatory T cells in patients with tuberculosis. Am J Respir Crit Care Med (2007) 0.84
Up-regulation of Fas expression by Pseudomonas aeruginosa-infected endothelial cells depends on modulation of iNOS and enhanced production of NO induced by bacterial type III secreted proteins. Int J Mol Med (2006) 0.83
Pure neural leprosy: steroids prevent neuropathy progression. Arq Neuropsiquiatr (2007) 0.83
The additional benefit of the ML Flow test to classify leprosy patients. Acta Trop (2009) 0.83
Draft genome sequence determination for cystic fibrosis and chronic granulomatous disease Burkholderia multivorans isolates. J Bacteriol (2012) 0.83
RJLs: a new family of Ras-related GTP-binding proteins. Gene (2004) 0.82
ExoU-induced vascular hyperpermeability and platelet activation in the course of experimental Pseudomonas aeruginosa pneumosepsis. Shock (2010) 0.82
Mycobacterium leprae induces NF-kappaB-dependent transcription repression in human Schwann cells. Biochem Biophys Res Commun (2005) 0.82
The level of PPD-specific IFN-gamma-producing CD4+ T cells in the blood predicts the in vivo response to PPD. Tuberculosis (Edinb) (2006) 0.81
Differential interaction of bacterial species from the Burkholderia cepacia complex with human airway epithelial cells. Microbes Infect (2007) 0.81
Whole blood assay to access T cell-immune responses to Mycobacterium tuberculosis antigens in healthy Brazilian individuals. Mem Inst Oswaldo Cruz (2004) 0.81
Pseudomonas aeruginosa-induced production of free radicals by IFNgamma plus TNFalpha-activated human endothelial cells: mechanism of host defense or of bacterial pathogenesis? Immunol Cell Biol (2004) 0.81
Heparin-binding hemagglutinin (HBHA) of Mycobacterium leprae is expressed during infection and enhances bacterial adherence to epithelial cells. FEMS Microbiol Lett (2009) 0.81
Single nucleotide polymorphisms (SNPs) at -238 and -308 positions in the TNFalpha promoter: clinical and bacteriological evaluation in leprosy. Int J Lepr Other Mycobact Dis (2004) 0.80
Interleukin-4 regulates the expression of CD209 and subsequent uptake of Mycobacterium leprae by Schwann cells in human leprosy. Infect Immun (2010) 0.80
Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis. PLoS Negl Trop Dis (2012) 0.79
Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease. PLoS Negl Trop Dis (2013) 0.79
Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector. Toxicon (2007) 0.79
Cytokines and Mycobacterium leprae induce apoptosis in human Schwann cells. J Neuropathol Exp Neurol (2005) 0.79
The proteasome function is required for Mycobacterium leprae-induced apoptosis and cytokine secretion. Immunol Lett (2007) 0.78
Potential mechanisms underlying the acute lung dysfunction and bacterial extrapulmonary dissemination during Burkholderia cenocepacia respiratory infection. Respir Res (2010) 0.78