Published in Eur J Cell Biol on June 14, 2012
Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. J Control Release (2007) 1.73
Cysteine cathepsins (proteases)--on the main stage of cancer? Cancer Cell (2004) 1.27
Cystatins in immune system. J Cancer (2012) 1.22
Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro. Exp Cell Res (2003) 1.20
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase. J Med Chem (2010) 1.15
Synthesis and biological evaluation of (6- and 7-phenyl) coumarin derivatives as selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1. J Med Chem (2010) 1.10
Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer. Adv Enzyme Regul (2002) 1.08
Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells. Exp Cell Res (2006) 1.05
Role of cysteine cathepsins in matrix degradation and cell signalling. Connect Tissue Res (2008) 1.05
Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis. Cancer Gene Ther (2003) 1.05
Intracellular proteolytic activity of cathepsin B is associated with capillary-like tube formation by endothelial cells in vitro. J Cell Biochem (2006) 1.04
The role of cathepsin X in the migration and invasiveness of T lymphocytes. J Cell Sci (2008) 1.01
High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas. Acta Neuropathol (2009) 0.99
Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins. Immunology (2008) 0.98
Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds. ChemMedChem (2011) 0.97
γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways. Biochem J (2012) 0.95
Cystatin C as a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma. Cancer Lett (2006) 0.95
Inhibitory properties of cystatin F and its localization in U937 promonocyte cells. FEBS J (2005) 0.93
Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors. J Cancer Res Clin Oncol (2009) 0.91
Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells. Int J Biochem Cell Biol (2009) 0.91
5-Benzylidenethiazolidin-4-ones as multitarget inhibitors of bacterial Mur ligases. ChemMedChem (2010) 0.91
Nanoscale polymer carriers to deliver chemotherapeutic agents to tumours. Expert Opin Biol Ther (2005) 0.90
Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAcβ1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis. J Biol Chem (2012) 0.90
Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer. Anticancer Res (2003) 0.90
Proteins of higher fungi--from forest to application. Trends Biotechnol (2012) 0.89
Lysosomal enzymes, cathepsins in brain tumour invasion. J Neurooncol (2002) 0.89
Cystatins in non-small cell lung cancer: tissue levels, localization and relation to prognosis. Oncol Rep (2006) 0.89
Purification, characterization and cloning of a ricin B-like lectin from mushroom Clitocybe nebularis with antiproliferative activity against human leukemic T cells. Biochim Biophys Acta (2008) 0.89
The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer. Eur J Clin Invest (2010) 0.89
Natural killer cells as effectors of selection and differentiation of stem cells: role in resolution of inflammation. J Immunotoxicol (2014) 0.88
Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF. Bioorg Chem (2009) 0.88
Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis. J Med Chem (2014) 0.88
Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. Cancer Detect Prev (2002) 0.87
Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness. Mol Cancer (2009) 0.87
Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB). Bioorg Med Chem Lett (2009) 0.87
Cystatin incorporated in poly(lactide-co-glycolide) nanoparticles: development and fundamental studies on preservation of its activity. Eur J Pharm Sci (2004) 0.87
Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. Eur J Cell Biol (2012) 0.87
Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X. J Leukoc Biol (2008) 0.87
Stefin a and stefin B: markers for prognosis in operable squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys (2007) 0.87
Cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells. J Biol Chem (2012) 0.86
Synthesis and antibacterial activity of 5-ylidenethiazolidin-4-ones and 5-benzylidene-4,6-pyrimidinediones. Eur J Med Chem (2009) 0.85
Structural basis of trypsin inhibition and entomotoxicity of cospin, serine protease inhibitor involved in defense of Coprinopsis cinerea fruiting bodies. J Biol Chem (2011) 0.85
Screening of selected food and medicinal plant extracts for pancreatic lipase inhibition. Phytother Res (2009) 0.85
Versatile loops in mycocypins inhibit three protease families. J Biol Chem (2009) 0.85
DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function. J Leukoc Biol (2011) 0.85
Poly(lactide-co-glycolide) nanoparticles as a carrier system for delivering cysteine protease inhibitor cystatin into tumor cells. Exp Cell Res (2004) 0.85
Cysteine cathepsins in neurological disorders. Mol Neurobiol (2013) 0.85
γ-1-syntrophin mediates trafficking of γ-enolase towards the plasma membrane and enhances its neurotrophic activity. Neurosignals (2011) 0.84
Differentiation- and maturation-dependent content, localization, and secretion of cystatin C in human dendritic cells. J Leukoc Biol (2005) 0.84
Immunonanoparticles--an effective tool to impair harmful proteolysis in invasive breast tumor cells. FEBS J (2007) 0.84
Novel inhibitors of trihydroxynaphthalene reductase with antifungal activity identified by ligand-based and structure-based virtual screening. J Chem Inf Model (2011) 0.83
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor. J Med Chem (2014) 0.83
Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD). J Med Chem (2011) 0.83
Microbial and fungal protease inhibitors--current and potential applications. Appl Microbiol Biotechnol (2012) 0.83
Preparation and Reactivity of 5-benzylidenebarbituric and 5-benzylidene-2-thiobarbituric Acids. Acta Chim Slov (2011) 0.83
Selective inhibitors of aldo-keto reductases AKR1C1 and AKR1C3 discovered by virtual screening of a fragment library. J Med Chem (2012) 0.83
Serum cystatin C in patients with head and neck carcinoma. Clin Chim Acta (2004) 0.83
Cathepsin X in serum from patients with colorectal cancer: relation to prognosis. Radiol Oncol (2012) 0.82
Cysteine cathepsins: regulators of antitumour immune response. Expert Opin Biol Ther (2006) 0.82
Exploration of the chemical space of novel naphthalene-sulfonamide and anthranilic Acid-based inhibitors of penicillin-binding proteins. Acta Chim Slov (2012) 0.82
Profilin 1 as a target for cathepsin X activity in tumor cells. PLoS One (2013) 0.82
Cathepsin X prevents an effective immune response against Helicobacter pylori infection. Eur J Cell Biol (2009) 0.82
Comparison of bacterial and phage display peptide libraries in search of target-binding motif. Appl Biochem Biotechnol (2005) 0.82
Genotoxicity of trivalent chromium in bacterial cells. Possible effects on DNA topology. Chem Res Toxicol (2002) 0.82
Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety. PLoS One (2011) 0.81
Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles. Nanomedicine (Lond) (2010) 0.81
N-Benzoyl anthranilic acid derivatives as selective inhibitors of aldo-keto reductase AKR1C3. Bioorg Med Chem Lett (2012) 0.81
Novel toll-like receptor 4 (TLR4) antagonists identified by structure- and ligand-based virtual screening. Eur J Med Chem (2013) 0.81
CNL, a ricin B-like lectin from mushroom Clitocybe nebularis, induces maturation and activation of dendritic cells via the toll-like receptor 4 pathway. Immunology (2011) 0.81
Basidiomycete Clitocybe nebularis is rich in lectins with insecticidal activities. Appl Microbiol Biotechnol (2011) 0.81
Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells. J Leukoc Biol (2011) 0.80
Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF. Eur J Med Chem (2013) 0.80
Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes. Immunology (2004) 0.80
Iron-regulated surface determinant B (IsdB) promotes Staphylococcus aureus adherence to and internalization by non-phagocytic human cells. Cell Microbiol (2013) 0.80
Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase. Bioorg Med Chem Lett (2008) 0.80
A novel β-trefoil lectin from the parasol mushroom (Macrolepiota procera) is nematotoxic. FEBS J (2014) 0.80
New biologically active epidioxysterols from Stereum hirsutum. Bioorg Med Chem Lett (2007) 0.80
Endocrine disruptome--an open source prediction tool for assessing endocrine disruption potential through nuclear receptor binding. J Chem Inf Model (2014) 0.80
Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives. J Med Chem (2013) 0.80
Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms. J Biol Chem (2011) 0.79
LFA-1 fine-tuning by cathepsin X. IUBMB Life (2011) 0.79
Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X. Aging Cell (2013) 0.79
Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding. Eur J Immunol (2009) 0.79
Three-dimensional invasion of macrophages is mediated by cysteine cathepsins in protrusive podosomes. Eur J Immunol (2012) 0.79
MurD enzymes from different bacteria: evaluation of inhibitors. Biochem Pharmacol (2012) 0.79
Regulation of cathepsin B activity by 2A2 monoclonal antibody. FEBS J (2009) 0.79