Published in Trends Parasitol on June 22, 2012
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Combined therapy of iron chelator and antioxidant completely restores brain dysfunction induced by iron toxicity. PLoS One (2014) 0.84
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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature (2011) 4.63
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Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease. Prog Retin Eye Res (2012) 1.94
Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One (2011) 1.81
Current perspectives on the mechanism of action of artemisinins. Int J Parasitol (2006) 1.80
IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development. Proc Natl Acad Sci U S A (2007) 1.77
Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo. Invest Ophthalmol Vis Sci (2004) 1.68
Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway. Int J Biochem Cell Biol (2008) 1.64
Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice. PLoS One (2012) 1.59
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission? J Neuroinflammation (2011) 1.56
Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J Immunol (2008) 1.42
Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria. Int J Parasitol (2006) 1.35
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Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res (2009) 1.31
Connecting inflammation with glutamate agonism in suicidality. Neuropsychopharmacology (2012) 1.31
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The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation. Cell Res (2008) 1.26
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells. Neuroreport (2006) 1.26
Murine cerebral malaria: the whole story. Trends Parasitol (2010) 1.24
Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One (2012) 1.23
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons. Proc Natl Acad Sci U S A (2009) 1.20
Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: differences in asthma. J Cell Physiol (2008) 1.18
Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. Analyst (2011) 1.17
Detection and characterization of OX40 ligand expression in human airway smooth muscle cells: a possible role in asthma? J Allergy Clin Immunol (2004) 1.16
The excitotoxin quinolinic acid induces tau phosphorylation in human neurons. PLoS One (2009) 1.15
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Microparticle-associated nucleic acids mediate trait dominance in cancer. FASEB J (2011) 1.13
Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury. Am J Pathol (2011) 1.12
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Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. J Biol Chem (2008) 1.08
CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. J Allergy Clin Immunol (2005) 1.08
Characterisation of the expression of NMDA receptors in human astrocytes. PLoS One (2010) 1.08
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation. J Biol Chem (2006) 1.08
Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons. Int J Tryptophan Res (2009) 1.07
Neuroprotective effect of natural products against Alzheimer's disease. Neurochem Res (2012) 1.07
Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons. Neurotox Res (2009) 1.07
Brain gene expression, metabolism, and bioenergetics: interrelationships in murine models of cerebral and noncerebral malaria. FASEB J (2004) 1.06
Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations. J Neurosci (2009) 1.03
The kynurenine pathway in brain tumor pathogenesis. Cancer Res (2012) 1.03
Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria. Int J Parasitol (2010) 1.03
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. J Infect Dis (2002) 1.03
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Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Prog Neurobiol (2010) 1.02
The microcirculation in severe malaria. Microcirculation (2004) 1.02
Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats. FEBS J (2011) 1.02
Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. J Infect Dis (2003) 1.01
Altered pericyte-endothelial relations in the rat retina during aging: implications for vessel stability. Neurobiol Aging (2006) 1.01
Heme moves to center stage in cerebral malaria. Nat Med (2007) 1.01
Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone. Am J Physiol Regul Integr Comp Physiol (2012) 1.01
Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease. J Neuroinflammation (2009) 1.00
Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons. FEBS J (2009) 1.00
p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells. J Neurooncol (2012) 1.00
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Invest Ophthalmol Vis Sci (2011) 1.00
Phenotypic characterization of neural stem cells from human fetal spinal cord: synergistic effect of LIF and BMP4 to generate astrocytes. Glia (2007) 0.99
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Increased expression of indoleamine 2,3-dioxygenase in murine malaria infection is predominantly localised to the vascular endothelium. Int J Parasitol (2004) 0.98
Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease. Amino Acids (2013) 0.98
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M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. PLoS One (2012) 0.96
Placental hypoxia during placental malaria. J Infect Dis (2008) 0.96
Probucol promotes functional reendothelialization in balloon-injured rabbit aortas. Circulation (2003) 0.96
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Isolating vessels from the mouse brain for gene expression analysis using laser capture microdissection. Brain Res Brain Res Protoc (2002) 0.96
Gp91(phox) contributes to the development of experimental inflammatory bowel disease. Immunol Cell Biol (2011) 0.95
Cyclooxygenase-2 in the pathogenesis of murine cerebral malaria. J Infect Dis (2004) 0.95
Cooperation between β- and γ-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. FASEB J (2012) 0.94
Effect of dietary supplementation of dates in Alzheimer's disease APPsw/2576 transgenic mice on oxidative stress and antioxidant status. Nutr Neurosci (2014) 0.94
1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan. Comp Biochem Physiol B Biochem Mol Biol (2010) 0.93
Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis. J Immunol (2012) 0.93
Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain. PLoS One (2013) 0.93
CNS inflammation and bone marrow neuropathy in type 1 diabetes. Am J Pathol (2013) 0.92
Synthesis of artemiside and its effects in combination with conventional drugs against severe murine malaria. Antimicrob Agents Chemother (2011) 0.92
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress. Cancer Res (2013) 0.92
The correlation between proinflammatory cytokines, MAdCAM-1 and cellular infiltration in the inflamed colon from TNF-alpha gene knockout mice. Immunol Cell Biol (2007) 0.91
Differential microRNA expression in experimental cerebral and noncerebral malaria. Infect Immun (2011) 0.91
Microparticles from mycobacteria-infected macrophages promote inflammation and cellular migration. J Immunol (2012) 0.91
A role for Fas-Fas ligand interactions during the late-stage neuropathological processes of experimental cerebral malaria. J Neuroimmunol (2006) 0.91
Role of the gut in visceral fat inflammation and metabolic disorders. Obesity (Silver Spring) (2011) 0.91
Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons. J Alzheimers Dis (2009) 0.91
Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3. PLoS One (2012) 0.91
Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. Int J Clin Exp Pathol (2011) 0.90
Proinflammatory cytokine interferon-gamma increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid beta peptide 1-42: implications for the pathogenesis of Alzheimer's disease. J Neurochem (2009) 0.90
Neuroprotective effects of hesperidin, a plant flavanone, on rotenone-induced oxidative stress and apoptosis in a cellular model for Parkinson's disease. Oxid Med Cell Longev (2013) 0.90
Neuroprotective effects of a variety of pomegranate juice extracts against MPTP-induced cytotoxicity and oxidative stress in human primary neurons. Oxid Med Cell Longev (2013) 0.90
Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls. Eur Arch Psychiatry Clin Neurosci (2012) 0.89
Reduced activity of the epithelial sodium channel in malaria-induced pulmonary oedema in mice. Int J Parasitol (2010) 0.89
Modulation of indoleamine-2,3-dioxygenase expression and activity by HIV-1 in human macrophages. Fundam Clin Pharmacol (2009) 0.89
Increased markers of oxidative stress in autistic children of the Sultanate of Oman. Biol Trace Elem Res (2011) 0.88