Published in Infect Immun on March 21, 2011
miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain. Cell Rep (2014) 0.83
Specific Roles of MicroRNAs in Their Interactions with Environmental Factors. J Nucleic Acids (2012) 0.80
MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood. J Neuroinfect Dis (2015) 0.79
Helminth excreted/secreted antigens repress expression of LPS-induced Let-7i but not miR-146a and miR-155 in human dendritic cells. Biomed Res Int (2012) 0.79
MicroRNAs in the Host-Apicomplexan Parasites Interactions: A Review of Immunopathological Aspects. Front Cell Infect Microbiol (2016) 0.79
The miRNA and mRNA Signatures of Peripheral Blood Cells in Humans Infected with Trypanosoma brucei gambiense. PLoS One (2013) 0.77
Experimental Models of Microvascular Immunopathology: The Example of Cerebral Malaria. J Neuroinfect Dis (2014) 0.76
Tying malaria and microRNAs: from the biology to future diagnostic perspectives. Malar J (2016) 0.76
MicroRNA profiling of the intestinal tissue of Kazakh sheep after experimental Echinococcus granulosus infection, using a high-throughput approach. Parasite (2016) 0.76
Molecular basis of human cerebral malaria development. Trop Med Health (2016) 0.75
Computational identification of novel microRNAs and their targets in the malarial vector, Anopheles stephensi. Syst Synth Biol (2015) 0.75
Circulating microRNAs in malaria infection: bench to bedside. Malar J (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
The functions of animal microRNAs. Nature (2004) 64.85
Prediction of mammalian microRNA targets. Cell (2003) 53.70
Combinatorial microRNA target predictions. Nat Genet (2005) 50.48
Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer (2006) 46.47
MicroRNA signatures in human cancers. Nat Rev Cancer (2006) 46.29
miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res (2006) 39.25
MicroRNA gene expression deregulation in human breast cancer. Cancer Res (2005) 27.56
Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24
Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science (1993) 14.91
MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell (2007) 9.33
miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell (2007) 9.08
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature (2008) 8.69
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol (2007) 8.05
Changes in the burden of malaria in sub-Saharan Africa. Lancet Infect Dis (2010) 7.42
MicroRNAs: new regulators of immune cell development and function. Nat Immunol (2008) 6.96
A role for Dicer in immune regulation. J Exp Med (2006) 5.81
The murine cerebral malaria phenomenon. Trends Parasitol (2009) 5.62
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A (2008) 5.15
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature (1998) 4.97
Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res (2008) 4.95
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal (2009) 4.73
Immunological processes in malaria pathogenesis. Nat Rev Immunol (2005) 3.80
Principles and effects of microRNA-mediated post-transcriptional gene regulation. Oncogene (2006) 3.51
Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children. JAMA (2007) 3.29
A trial of artemether or quinine in children with cerebral malaria. N Engl J Med (1996) 3.28
Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol (2003) 3.18
A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends Parasitol (2006) 2.90
A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J Biol Chem (2007) 2.89
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J (1998) 2.82
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol (1986) 2.79
MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components. Mol Immunol (2007) 2.24
Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol (2002) 2.12
Immunopathogenesis of cerebral malaria. Int J Parasitol (2006) 2.08
Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol (2009) 1.93
MiR-210--micromanager of the hypoxia pathway. Trends Mol Med (2010) 1.90
Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response. J Infect Dis (2009) 1.89
Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. Parasitology (2009) 1.87
Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis. Microbes Infect (2002) 1.81
Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology (1992) 1.78
Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210. FEBS Lett (2008) 1.75
The eye in cerebral malaria: what can it teach us? Trans R Soc Trop Med Hyg (2008) 1.66
Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology. Chem Immunol (2002) 1.61
Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and -independent apoptosis in human embryonic kidney cells. PLoS One (2009) 1.54
FADD: a regulator of life and death. Trends Immunol (2010) 1.51
Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice. Infect Immun (2010) 1.47
Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema. J Neurosci (2005) 1.45
Immunopathological changes in human cerebral malaria. Clin Neuropathol (1993) 1.40
NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection. J Biol Chem (2009) 1.40
Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol (2007) 1.38
CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs. Proc Natl Acad Sci U S A (2009) 1.38
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria. Am J Pathol (1998) 1.32
Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice. Exp Neurol (2006) 1.32
Early cytokine production is associated with protection from murine cerebral malaria. Infect Immun (2005) 1.32
Multiple E2F-induced microRNAs prevent replicative stress in response to mitogenic signaling. Mol Cell Biol (2010) 1.29
Apoptosis in experimental cerebral malaria: spatial profile of cleaved caspase-3 and ultrastructural alterations in different disease stages. Neuropathol Appl Neurobiol (2007) 1.28
Murine cerebral malaria: the whole story. Trends Parasitol (2010) 1.24
Mouse models for erythrocytic-stage malaria. Methods Mol Med (2002) 1.21
Correlation between enhanced vascular permeability, up-regulation of cellular adhesion molecules and monocyte adhesion to the endothelium in the retina during the development of fatal murine cerebral malaria. Am J Pathol (1996) 1.17
Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice. J Infect Dis (2005) 1.15
Conventional and experimental treatment of cerebral malaria. Int J Parasitol (2006) 1.12
Role of cytokines and adhesion molecules in malaria immunopathology. Stem Cells (1993) 1.09
Brain gene expression, metabolism, and bioenergetics: interrelationships in murine models of cerebral and noncerebral malaria. FASEB J (2004) 1.06
Helicobacter pylori and gastric cancer: possible role of microRNAs in this intimate relationship. Clin Microbiol Infect (2009) 1.04
Respective role of TNF receptors in the development of experimental cerebral malaria. J Neuroimmunol (1997) 1.04
No miRNA were found in Plasmodium and the ones identified in erythrocytes could not be correlated with infection. Malar J (2008) 0.96
Comparative clinical and experimental study on the pathogenesis of cerebral malaria. Contrib Microbiol Immunol (1983) 0.84
Micromanagement during the innate immune response. Sci STKE (2007) 0.82
Brain metabolic markers reflect susceptibility status in cytokine gene knockout mice with murine cerebral malaria. Int J Parasitol (2006) 0.80
The lack of suppressor of cytokine signalling-1 (SOCS1) protects mice from the development of cerebral malaria caused by Plasmodium berghei ANKA. Parasite Immunol (2003) 0.78
Role of immune mediators in the pathology of experimental murine cerebral malaria. Redox Rep (1999) 0.76
Peptidomic discovery of short open reading frame-encoded peptides in human cells. Nat Chem Biol (2012) 2.95
A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends Parasitol (2006) 2.90
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity. J Immunol (2002) 2.39
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene (2007) 2.24
Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med (2010) 2.12
Immunopathogenesis of cerebral malaria. Int J Parasitol (2006) 2.08
Malaria-induced acquisition of antibodies to Plasmodium falciparum variant surface antigens. Infect Immun (2002) 2.00
Endothelial microparticles: a potential contribution to the thrombotic complications of the antiphospholipid syndrome. Thromb Haemost (2004) 1.96
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol (2013) 1.91
Current perspectives on the mechanism of action of artemisinins. Int J Parasitol (2006) 1.80
Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway. Int J Biochem Cell Biol (2008) 1.64
Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria. Infect Immun (2004) 1.60
Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma. JAMA (2004) 1.60
Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice. PLoS One (2012) 1.59
Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum. Infect Immun (2006) 1.51
Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J Immunol (2008) 1.42
Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria. Int J Parasitol (2006) 1.35
Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice. Exp Neurol (2006) 1.32
Early cytokine production is associated with protection from murine cerebral malaria. Infect Immun (2005) 1.32
The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation. Cell Res (2008) 1.26
Bedside diagnosis of imported malaria using the Binax Now malaria antigen detection test. Scand J Infect Dis (2006) 1.26
Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria. Malar J (2008) 1.25
Murine cerebral malaria: the whole story. Trends Parasitol (2010) 1.24
Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens. Infect Immun (2004) 1.24
Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: differences in asthma. J Cell Physiol (2008) 1.18
Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. Analyst (2011) 1.17
Elevated cell-specific microparticles are a biological marker for cerebral dysfunctions in human severe malaria. PLoS One (2010) 1.17
Platelet-endothelial cell interactions in cerebral malaria: the end of a cordial understanding. Thromb Haemost (2009) 1.16
Detection and characterization of OX40 ligand expression in human airway smooth muscle cells: a possible role in asthma? J Allergy Clin Immunol (2004) 1.16
Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium. FASEB J (2009) 1.14
Cerebral malaria -- a neurovascular pathology with many riddles still to be solved. Curr Neurovasc Res (2004) 1.14
Microparticle-associated nucleic acids mediate trait dominance in cancer. FASEB J (2011) 1.13
Inhibition of endothelial activation: a new way to treat cerebral malaria? PLoS Med (2005) 1.09
Pathophysiology of cerebral malaria: role of host cells in the modulation of cytoadhesion. Ann N Y Acad Sci (2003) 1.09
CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. J Allergy Clin Immunol (2005) 1.08
Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome. J Infect Dis (2005) 1.08
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. J Biol Chem (2008) 1.08
Brain gene expression, metabolism, and bioenergetics: interrelationships in murine models of cerebral and noncerebral malaria. FASEB J (2004) 1.06
Microparticle conferred microRNA profiles--implications in the transfer and dominance of cancer traits. Mol Cancer (2012) 1.05
Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria. Int J Parasitol (2010) 1.03
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. J Infect Dis (2002) 1.03
Technical advance: autofluorescence as a tool for myeloid cell analysis. J Leukoc Biol (2010) 1.02
The microcirculation in severe malaria. Microcirculation (2004) 1.02
Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Prog Neurobiol (2010) 1.02
Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. J Infect Dis (2003) 1.01
Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes. Infect Immun (2003) 1.01
Cell vesiculation and immunopathology: implications in cerebral malaria. Microbes Infect (2006) 1.01
Heme moves to center stage in cerebral malaria. Nat Med (2007) 1.01
Increased expression of indoleamine 2,3-dioxygenase in murine malaria infection is predominantly localised to the vascular endothelium. Int J Parasitol (2004) 0.98
Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease. Amino Acids (2013) 0.98
Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons. J Physiol (2002) 0.96
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. J Acquir Immune Defic Syndr (2002) 0.96
Placental hypoxia during placental malaria. J Infect Dis (2008) 0.96
Probucol promotes functional reendothelialization in balloon-injured rabbit aortas. Circulation (2003) 0.96
Interferon-gamma synergises with tumour necrosis factor and lymphotoxin-alpha to enhance the mRNA and protein expression of adhesion molecules in mouse brain endothelial cells. Cytokine (2007) 0.96
Isolating vessels from the mouse brain for gene expression analysis using laser capture microdissection. Brain Res Brain Res Protoc (2002) 0.96
Human immunodeficiency virus infection alters tumor necrosis factor alpha production via Toll-like receptor-dependent pathways in alveolar macrophages and U1 cells. J Virol (2008) 0.95
Gp91(phox) contributes to the development of experimental inflammatory bowel disease. Immunol Cell Biol (2011) 0.95
Cyclooxygenase-2 in the pathogenesis of murine cerebral malaria. J Infect Dis (2004) 0.95
Cooperation between β- and γ-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. FASEB J (2012) 0.94
Metallothionein-I+II in neuroprotection. Biofactors (2009) 0.94
1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan. Comp Biochem Physiol B Biochem Mol Biol (2010) 0.93
Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis. J Immunol (2012) 0.93
Synthesis of artemiside and its effects in combination with conventional drugs against severe murine malaria. Antimicrob Agents Chemother (2011) 0.92
The correlation between proinflammatory cytokines, MAdCAM-1 and cellular infiltration in the inflamed colon from TNF-alpha gene knockout mice. Immunol Cell Biol (2007) 0.91
Microparticles from mycobacteria-infected macrophages promote inflammation and cellular migration. J Immunol (2012) 0.91
A role for Fas-Fas ligand interactions during the late-stage neuropathological processes of experimental cerebral malaria. J Neuroimmunol (2006) 0.91
Role of the gut in visceral fat inflammation and metabolic disorders. Obesity (Silver Spring) (2011) 0.91
Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1. Amino Acids (2014) 0.90
ATP-binding cassette transporter hallmarks tissue macrophages and modulates cytokine-triggered polarization programs. Eur J Immunol (2009) 0.90
Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. Int J Clin Exp Pathol (2011) 0.90