PubRank

Craig H Bassing

Author PubWeight™ 84.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Mol Cell 2006 3.53
2 ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature 2006 3.35
3 Activating Notch1 mutations in mouse models of T-ALL. Blood 2005 3.08
4 Control of sister chromatid recombination by histone H2AX. Mol Cell 2004 2.43
5 Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity. Nat Immunol 2004 2.38
6 Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. Adv Immunol 2005 2.19
7 Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Mol Cell 2009 2.08
8 RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol 2009 1.98
9 DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes. Nature 2008 1.88
10 Elucidation of IgH intronic enhancer functions via germ-line deletion. Proc Natl Acad Sci U S A 2005 1.85
11 H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature 2010 1.78
12 A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity 2002 1.74
13 Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev 2007 1.65
14 ATR and H2AX cooperate in maintaining genome stability under replication stress. J Biol Chem 2008 1.55
15 Antigen receptor allelic exclusion: an update and reappraisal. J Immunol 2010 1.54
16 MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. J Exp Med 2009 1.50
17 Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proc Natl Acad Sci U S A 2003 1.49
18 Histone H2AX is integral to hypoxia-driven neovascularization. Nat Med 2009 1.48
19 Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. Eur J Immunol 2008 1.48
20 Complementary functions of ATM and H2AX in development and suppression of genomic instability. Proc Natl Acad Sci U S A 2008 1.42
21 Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability. Mol Cell Biol 2008 1.37
22 ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification. J Exp Med 2010 1.36
23 Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. J Exp Med 2007 1.29
24 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proc Natl Acad Sci U S A 2006 1.27
25 Regulation of cell differentiation by the DNA damage response. Trends Cell Biol 2011 1.25
26 Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis. Proc Natl Acad Sci U S A 2009 1.25
27 Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination. J Exp Med 2009 1.24
28 Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. J Exp Med 2003 1.18
29 Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice. J Clin Invest 2010 1.17
30 Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proc Natl Acad Sci U S A 2011 1.05
31 Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. Immunity 2003 1.05
32 Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma. Cancer Res 2009 1.04
33 Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence. Immunity 2003 1.01
34 Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement. J Immunol 2008 0.98
35 Chromatin dynamics and locus accessibility in the immune system. Nat Immunol 2003 0.97
36 Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining. J Immunol 2008 0.94
37 The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. J Exp Med 2013 0.93
38 Posttranscriptional silencing of VbetaDJbetaCbeta genes contributes to TCRbeta allelic exclusion in mammalian lymphocytes. J Immunol 2010 0.93
39 Repair of chromosomal RAG-mediated DNA breaks by mutant RAG proteins lacking phosphatidylinositol 3-like kinase consensus phosphorylation sites. J Immunol 2011 0.92
40 Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. J Immunol 2010 0.91
41 The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells. J Exp Med 2006 0.90
42 Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications. Proc Natl Acad Sci U S A 2007 0.90
43 Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas. Proc Natl Acad Sci U S A 2013 0.90
44 Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Mol Cell Biol 2013 0.88
45 T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. J Exp Med 2002 0.88
46 Somatic inactivation of Tp53 in hematopoietic stem cells or thymocytes predisposes mice to thymic lymphomas with clonal translocations. Cell Cycle 2013 0.88
47 TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes. J Immunol 2009 0.87
48 Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. Proc Natl Acad Sci U S A 2013 0.85
49 Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia. Cell Cycle 2014 0.83
50 Differential regulation of proximal and distal Vbeta segments upstream of a functional VDJbeta1 rearrangement upon beta-selection. J Immunol 2011 0.82
51 Analysis of the complex genomic structure of Bcl-x and its relationship to Bcl-x(gamma) expression after CD28-dependent costimulation. Mol Immunol 2002 0.81
52 The sticky business of histone H2AX in V(D)J recombination, maintenance of genomic stability, and suppression of lymphoma. Immunol Res 2008 0.81
53 Histone H2AX suppresses translocations in lymphomas of Eμ-c-Myc transgenic mice that contain a germline amplicon of tumor-promoting genes. Cell Cycle 2013 0.81
54 Assembled DJ beta complexes influence TCR beta chain selection and peripheral V beta repertoire. J Immunol 2009 0.80
55 Cellular context-dependent effects of H2ax and p53 deletion on the development of thymic lymphoma. Blood 2010 0.80
56 Redundant and nonredundant functions of ATM and H2AX in αβ T-lineage lymphocytes. J Immunol 2012 0.80
57 Chipping away at gamma-H2AX foci. Cell Cycle 2009 0.80
58 Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks. J Immunol 2013 0.79
59 Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL. Cancer Immunol Res 2013 0.79
60 V(D)J recombinational accessibility-heading in the opposite direction? Nat Immunol 2004 0.79
61 Noncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences. J Immunol 2014 0.77
62 Fetal thymocyte development: putting a zinc finger on it? Nat Immunol 2006 0.77
63 Deciphering the DNA damage histone code. Cell Cycle 2010 0.76
64 ATM prevents unattended DNA double strand breaks on site and in generations to come. Cancer Biol Ther 2007 0.76
65 V(D)J recombination causes dangerous chromosome liaisons in developing thymocytes. Cell Cycle 2009 0.76
66 Molecular biology: case of mistaken identity. Nature 2004 0.75
67 Foxos around make B cells tolerable. Nat Immunol 2008 0.75
68 Somatic inactivation of ATM in hematopoietic cells predisposes mice to cyclin D3 dependent T cell acute lymphoblastic leukemia. Cell Cycle 2015 0.75
69 Molecular Analysis of Mouse T Cell Receptor α and β Gene Rearrangements. Methods Mol Biol 2016 0.75