Published in Mol Microbiol on July 13, 2012
Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. Science (2013) 1.23
The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets. Antibiotics (Basel) (2016) 0.80
Chemoenzymatic syntheses of water-soluble lipid I fluorescent probes. Tetrahedron Lett (2015) 0.79
Delayed lysis confers resistance to the nucleoside analogue 5-fluorouracil and alleviates mutation accumulation in the single-stranded DNA bacteriophage ϕX174. J Virol (2014) 0.76
Autotransporter-based antigen display in bacterial ghosts. Appl Environ Microbiol (2014) 0.75
Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis. Antibiotics (Basel) (2016) 0.75
Genetically Determined Variation in Lysis Time Variance in the Bacteriophage φX174. G3 (Bethesda) (2016) 0.75
New Insight into the Catalytic Mechanism of Bacterial MraY from Enzyme Kinetics and Docking Studies. J Biol Chem (2016) 0.75
Combining Genes from Multiple Phages for Improved Cell Lysis and DNA Transfer from Escherichia coli to Bacillus subtilis. PLoS One (2016) 0.75
Re-directing bacterial microcompartment systems to enhance recombinant expression of lysis protein E from bacteriophage ϕX174 in Escherichia coli. Microb Cell Fact (2017) 0.75
Nucleotide sequence of bacteriophage phi X174 DNA. Nature (1977) 95.69
Prokaryotes: the unseen majority. Proc Natl Acad Sci U S A (1998) 21.41
High abundance of viruses found in aquatic environments. Nature (1989) 15.01
The Jpred 3 secondary structure prediction server. Nucleic Acids Res (2008) 13.32
High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science (1989) 8.73
The process of infection with bacteriophage phi-X174. X. Mutations in a phi-X Lysis gene. J Mol Biol (1966) 5.64
Holins: the protein clocks of bacteriophage infections. Annu Rev Microbiol (2000) 5.30
Bacteriophage lysis: mechanism and regulation. Microbiol Rev (1992) 4.95
Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature (2007) 4.60
Phages will out: strategies of host cell lysis. Trends Microbiol (2000) 3.07
Proline-induced distortions of transmembrane helices. J Mol Biol (2002) 2.76
Holins: form and function in bacteriophage lysis. FEMS Microbiol Rev (1995) 2.59
Recent advances in the formation of the bacterial peptidoglycan monomer unit. Nat Prod Rep (2001) 2.51
Recursive PCR: a novel technique for total gene synthesis. Protein Eng (1992) 2.48
The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc Natl Acad Sci U S A (2004) 2.19
Tuning Escherichia coli for membrane protein overexpression. Proc Natl Acad Sci U S A (2008) 2.11
Second-site revertants of an inactive T4 lysozyme mutant restore activity by restructuring the active site cleft. Biochemistry (1991) 2.03
Phages in nature. Bacteriophage (2011) 2.00
Lysis of Escherichia coli by induction of cloned phi X174 genes. Mol Gen Genet (1982) 1.88
Lytic action of cloned phi X174 gene E. J Virol (1982) 1.72
Phospho-MurNAc-pentapeptide translocase (MraY) as a target for antibacterial agents and antibacterial proteins. Infect Disord Drug Targets (2006) 1.57
Topological analysis of the MraY protein catalysing the first membrane step of peptidoglycan synthesis. Mol Microbiol (1999) 1.50
Bacteriophage and their lysins for elimination of infectious bacteria. FEMS Microbiol Rev (2009) 1.48
slyD, a host gene required for phi X174 lysis, is related to the FK506-binding protein family of peptidyl-prolyl cis-trans-isomerases. J Biol Chem (1994) 1.39
MraY Inhibitors as Novel Antibacterial Agents. Curr Top Med Chem (2005) 1.35
Genetic evidence that the bacteriophage phi X174 lysis protein inhibits cell wall synthesis. Proc Natl Acad Sci U S A (2000) 1.32
Deletion and fusion analysis of the phage phi X174 lysis gene E. Gene (1985) 1.25
Mutational analysis of slyD, an Escherichia coli gene encoding a protein of the FKBP immunophilin family. Mol Microbiol (1997) 1.25
Breaking free: "protein antibiotics" and phage lysis. Res Microbiol (2002) 1.24
The lysis protein E of phi X174 is a specific inhibitor of the MraY-catalyzed step in peptidoglycan synthesis. J Biol Chem (2000) 1.13
Phenylalanine promotes interaction of transmembrane domains via GxxxG motifs. J Mol Biol (2007) 1.12
Phospho-N-acetyl-muramyl-pentapeptide translocase from Escherichia coli: catalytic role of conserved aspartic acid residues. J Bacteriol (2004) 1.11
Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli. J Biol Chem (1992) 1.10
Lytic activity localized to membrane-spanning region of phi X174 E protein. Mol Gen Genet (1986) 1.04
A high-throughput, homogeneous, fluorescence resonance energy transfer-based assay for phospho-N-acetylmuramoyl-pentapeptide translocase (MraY). J Biomol Screen (2012) 1.03
The Escherichia coli FKBP-type PPIase SlyD is required for the stabilization of the E lysis protein of bacteriophage phi X174. Mol Microbiol (2002) 1.02
Evolutionary dominance of holin lysis systems derives from superior genetic malleability. Microbiology (2008) 1.02
Interaction of the transmembrane domain of lysis protein E from bacteriophage phiX174 with bacterial translocase MraY and peptidyl-prolyl isomerase SlyD. Microbiology (2006) 0.99
Mechanistic analysis of muraymycin analogues: a guide to the design of MraY inhibitors. J Med Chem (2011) 0.94
Influence of C-terminal modifications of phi X174 lysis gene E on its lysis-inducing properties. J Gen Virol (1985) 0.92
Purification and functional characterization of phiX174 lysis protein E. Biochemistry (2009) 0.88
Genetic analysis of MraY inhibition by the phiX174 protein E. Genetics (2008) 0.85
Proline 21, a residue within the alpha-helical domain of phiX174 lysis protein E, is required for its function in Escherichia coli. Mol Microbiol (1997) 0.83
Enhancement of bacteriolysis of shuffled phage PhiX174 gene E. Virol J (2011) 0.80
Synthesis and biological evaluation of a diazepanone-based library of liposidomycins analogs as MraY inhibitors. Eur J Med Chem (2011) 0.78
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA. J Mol Biol (2002) 3.76
Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY. J Cell Biol (2005) 1.93
A large conformational change of the translocation ATPase SecA. Proc Natl Acad Sci U S A (2004) 1.86
Crystal structure of the long-chain fatty acid transporter FadL. Science (2004) 1.74
Model for eukaryotic tail-anchored protein binding based on the structure of Get3. Proc Natl Acad Sci U S A (2009) 1.59
Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Mol Cell (2007) 1.59
Structural characterization of the Get4/Get5 complex and its interaction with Get3. Proc Natl Acad Sci U S A (2010) 1.49
Modeling the effects of prl mutations on the Escherichia coli SecY complex. J Bacteriol (2005) 1.40
The complex process of GETting tail-anchored membrane proteins to the ER. Curr Opin Struct Biol (2012) 1.12
A structural model of the Sgt2 protein and its interactions with chaperones and the Get4/Get5 complex. J Biol Chem (2011) 1.11
Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface. Cell Rep (2012) 1.05
Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue. EMBO J (2011) 1.03
Precise timing of ATPase activation drives targeting of tail-anchored proteins. Proc Natl Acad Sci U S A (2013) 0.93
Get5 carboxyl-terminal domain is a novel dimerization motif that tethers an extended Get4/Get5 complex. J Biol Chem (2012) 0.93
USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation. Elife (2014) 0.90
The glove-like structure of the conserved membrane protein TatC provides insight into signal sequence recognition in twin-arginine translocation. Structure (2013) 0.86
Structure of the twin-arginine signal-binding protein DmsD from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.84
Ultrastructure and complex polar architecture of the human pathogen Campylobacter jejuni. Microbiologyopen (2014) 0.81
A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides. Anal Bioanal Chem (2015) 0.75