Published in Science on January 01, 2009
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol (2010) 9.35
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell (2011) 9.16
Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron (2011) 8.06
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell (2011) 6.80
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci (2010) 5.12
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci (2011) 4.15
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev (2011) 4.09
Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet (2009) 3.66
Neurotrophin regulation of neural circuit development and function. Nat Rev Neurosci (2013) 3.53
A role for the elongator complex in zygotic paternal genome demethylation. Nature (2010) 3.27
Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat Neurosci (2011) 3.27
Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell (2014) 3.17
Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J Cell Biol (2010) 3.16
DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature (2010) 2.74
A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell (2012) 2.72
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron (2009) 2.72
Direct lineage conversions: unnatural but useful? Nat Biotechnol (2011) 2.69
Regulation and function of DNA methylation in plants and animals. Cell Res (2011) 2.41
Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell (2013) 2.40
Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci (2010) 2.39
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nat Neurosci (2013) 2.38
DNA methylation and memory formation. Nat Neurosci (2010) 2.31
Neuronal activity-regulated gene transcription in synapse development and cognitive function. Cold Spring Harb Perspect Biol (2011) 2.27
Synaptic dysregulation in a human iPS cell model of mental disorders. Nature (2014) 2.12
Decreased serum BDNF levels in patients with epileptic and psychogenic nonepileptic seizures. Neurology (2010) 2.10
Adult neural stem cells bridge their niche. Cell Stem Cell (2012) 1.97
DNA methylation and demethylation in mammals. J Biol Chem (2011) 1.89
Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. Nat Neurosci (2010) 1.87
Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron (2013) 1.86
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role. Adv Nutr (2012) 1.80
DNA methylation and its basic function. Neuropsychopharmacology (2012) 1.76
Brain function and chromatin plasticity. Nature (2010) 1.75
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nat Neurosci (2015) 1.75
Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways. Nat Neurosci (2010) 1.68
DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet (2009) 1.68
DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle (2009) 1.64
Adult neural stem cells in the mammalian central nervous system. Cell Res (2009) 1.64
TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron (2013) 1.64
DNA methylation presents distinct binding sites for human transcription factors. Elife (2013) 1.63
Epigenetic regulation of memory formation and maintenance. Learn Mem (2013) 1.62
Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol Aging (2010) 1.61
Immune influence on adult neural stem cell regulation and function. Neuron (2009) 1.59
Genome-wide epigenetic regulation by early-life trauma. Arch Gen Psychiatry (2012) 1.57
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle (2011) 1.55
Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later. Cell Stem Cell (2015) 1.54
Signaling mechanisms regulating adult neural stem cells and neurogenesis. Biochim Biophys Acta (2012) 1.50
Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. J Neurosci (2009) 1.50
Mechanisms of specificity in neuronal activity-regulated gene transcription. Prog Neurobiol (2011) 1.49
Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia. Cell (2012) 1.48
Signaling in adult neurogenesis. Curr Opin Neurobiol (2010) 1.45
Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans. Neuropsychopharmacology (2012) 1.45
Epigenetic mechanisms of depression and antidepressant action. Annu Rev Pharmacol Toxicol (2012) 1.45
Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression. Mol Cell (2015) 1.44
Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits. Neuron (2016) 1.43
Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell Stem Cell (2013) 1.42
The role of Bisphenol A in shaping the brain, epigenome and behavior. Horm Behav (2010) 1.42
Orchestrating transcriptional control of adult neurogenesis. Genes Dev (2012) 1.41
Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology (2010) 1.41
The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. Neuropsychopharmacology (2012) 1.40
Epigenetic regulation of oligodendrocyte identity. Trends Neurosci (2010) 1.36
Regulation of chromatin structure in memory formation. Curr Opin Neurobiol (2009) 1.35
Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain. Neuropsychopharmacology (2011) 1.34
The timing for neuronal maturation in the adult hippocampus is modulated by local network activity. J Neurosci (2011) 1.32
Localized CT-guided irradiation inhibits neurogenesis in specific regions of the adult mouse brain. Radiat Res (2011) 1.30
Epigenetic mechanisms in learned fear: implications for PTSD. Neuropsychopharmacology (2012) 1.30
DNA glycosylases: in DNA repair and beyond. Chromosoma (2011) 1.29
Extensive changes in DNA methylation are associated with expression of mutant huntingtin. Proc Natl Acad Sci U S A (2013) 1.28
Gadd45 stress sensors in malignancy and leukemia. Crit Rev Oncog (2011) 1.27
Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind. Neurobiol Dis (2010) 1.26
Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity. J Neurosci (2012) 1.20
Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels. Genome Biol (2010) 1.20
Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis. Neuropsychopharmacology (2011) 1.17
Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development. J Child Psychol Psychiatry (2011) 1.16
A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice. Psychopharmacology (Berl) (2011) 1.16
Cognitive neuroepigenetics: a role for epigenetic mechanisms in learning and memory. Neurobiol Learn Mem (2010) 1.16
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest (2010) 1.14
Dynamics of DNA methylation in aging and Alzheimer's disease. DNA Cell Biol (2012) 1.13
Crosstalk among Epigenetic Pathways Regulates Neurogenesis. Front Neurosci (2012) 1.10
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. J Clin Invest (2013) 1.09
Stress sensor Gadd45 genes as therapeutic targets in cancer. Cancer Ther (2009) 1.09
Impact of diet on adult hippocampal neurogenesis. Genes Nutr (2009) 1.08
Epigenetics in the human brain. Neuropsychopharmacology (2012) 1.08
Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients. Transl Psychiatry (2012) 1.08
Active DNA demethylation in plants and animals. Cold Spring Harb Symp Quant Biol (2012) 1.07
Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair. Nat Neurosci (2015) 1.06
Epigenetic treatments for cognitive impairments. Neuropsychopharmacology (2011) 1.05
DNA methylation of BDNF as a biomarker of early-life adversity. Proc Natl Acad Sci U S A (2014) 1.05
Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment. Neuropsychopharmacology (2012) 1.04
Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy. Brain (2014) 1.04
Injury-dependent Müller glia and ganglion cell reprogramming during tissue regeneration requires Apobec2a and Apobec2b. J Neurosci (2012) 1.04
Sex-specific and strain-dependent effects of early life adversity on behavioral and epigenetic outcomes. Front Psychiatry (2013) 1.04
Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders. Neural Plast (2012) 1.03
The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life. Epigenetics (2011) 1.03
Norepinephrine directly activates adult hippocampal precursors via beta3-adrenergic receptors. J Neurosci (2010) 1.03
Epigenetic regulation of pluripotency and differentiation. Circ Res (2014) 1.02
BDNF deregulation in Rett syndrome. Neuropharmacology (2013) 1.02
Analysis of DNA methylation reveals a partial reprogramming of the Müller glia genome during retina regeneration. Proc Natl Acad Sci U S A (2013) 1.02
DNA demethylation by TDG. Epigenomics (2012) 1.01
Origins of aberrant DNA methylation in acute myeloid leukemia. Leukemia (2013) 1.00
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet (2003) 25.57
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci (2005) 8.96
DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science (2003) 8.81
Cyclical DNA methylation of a transcriptionally active promoter. Nature (2008) 7.62
GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature (2005) 7.04
DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation. Cell (2006) 6.11
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature (2007) 5.54
Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci (2008) 5.12
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science (2002) 4.88
Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res (2007) 4.13
Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci (2008) 3.86
Immune transcriptome alterations in the temporal cortex of subjects with autism. Neurobiol Dis (2008) 2.88
Spatial exploration-induced Arc mRNA and protein expression: evidence for selective, network-specific reactivation. J Neurosci (2005) 2.69
Increased neurogenesis in a model of electroconvulsive therapy. Biol Psychiatry (2000) 2.48
GADD45A does not promote DNA demethylation. PLoS Genet (2008) 2.36
Demethylase activity is directed by histone acetylation. J Biol Chem (2001) 1.91
Effects of visual experience on activity-dependent gene regulation in cortex. Nat Neurosci (2006) 1.71
Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a. Oncogene (2002) 1.59
Gadd45beta is important for perpetuating cognate and inflammatory signals in T cells. Nat Immunol (2003) 1.52
Is there an epigenetic component in long-term memory? J Theor Biol (1999) 1.32
Activity-dependent regulation of neuronal plasticity and self repair. Prog Brain Res (2000) 1.29
Base excision DNA repair defect in Gadd45a-deficient cells. Oncogene (2007) 1.27
Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms. J Mol Neurosci (1998) 1.27
Electroconvulsive seizure-induced gene expression profile of the hippocampus dentate gyrus granule cell layer. J Neurochem (2006) 1.26
Identification of novel light-induced genes in the suprachiasmatic nucleus. BMC Neurosci (2007) 1.17
Characterization of the 1B promoter of fibroblast growth factor 1 and its expression in the adult and developing mouse brain. J Biol Chem (1996) 0.99
Cloning and characterization of a novel form of mouse fibroblast growth factor-1 (FGF-1) mRNA, FGF-1.G: differential expression of FGF-1 and FGF-1.G mRNAs during embryonic development and in postnatal tissues. Biochim Biophys Acta (2001) 0.91
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science (2005) 11.31
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature (2012) 10.74
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity (2006) 10.58
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell (2011) 9.75
Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol (2006) 9.53
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature (2008) 9.16
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell (2011) 9.16
Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A (2004) 9.00
Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci (2005) 8.96
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci U S A (2006) 8.27
Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron (2011) 8.06
MAP kinases in the immune response. Annu Rev Immunol (2001) 7.62
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med (2004) 7.49
Interchromosomal associations between alternatively expressed loci. Nature (2005) 7.45
GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature (2005) 7.04
IRAK-M is a negative regulator of Toll-like receptor signaling. Cell (2002) 6.79
T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity (2007) 6.61
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature (2007) 6.58
Caspases 3 and 7: key mediators of mitochondrial events of apoptosis. Science (2006) 6.55
Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J Neurosci (2006) 6.48
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol (2007) 6.20
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity (2006) 6.00
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci U S A (2005) 5.96
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature (2002) 5.95
Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity (2006) 5.91
Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity (2007) 5.73
The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A (2008) 5.59
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell (2004) 5.50
Toll-like receptor 3 promotes cross-priming to virus-infected cells. Nature (2005) 5.32
A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain. Neuron (2007) 5.31
A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol (2009) 5.26
A toll-like receptor that prevents infection by uropathogenic bacteria. Science (2004) 5.26
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. J Clin Invest (2009) 5.09
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 4.95
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A (2004) 4.88
TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science (2005) 4.86
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med (2005) 4.85
The NLR gene family: a standard nomenclature. Immunity (2008) 4.77
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell (2007) 4.76
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol (2006) 4.70
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat Immunol (2004) 4.67
Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity (2008) 4.67
TGF-beta: a master of all T cell trades. Cell (2008) 4.60
Transforming growth factor-beta in T-cell biology. Nat Rev Immunol (2002) 4.50
Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med (2007) 4.47
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. Nat Immunol (2006) 4.44
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med (2005) 4.28
Natural regulatory T cells control the development of atherosclerosis in mice. Nat Med (2006) 4.28
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol (2003) 4.15
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature (2002) 4.15
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A (2004) 4.12
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity (2007) 4.07
Control of TH17 cells occurs in the small intestine. Nature (2011) 4.03
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity (2006) 4.02
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer (2013) 4.02
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci U S A (2009) 3.99
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med (2006) 3.76
Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proc Natl Acad Sci U S A (2006) 3.74
The inflammasome: first line of the immune response to cell stress. Cell (2006) 3.73
Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. Gastroenterology (2010) 3.57
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host Microbe (2007) 3.52
In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics. Cell (2011) 3.47
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A (2003) 3.46
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med (2005) 3.43
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J Exp Med (2008) 3.39
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity (2011) 3.38
OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands. J Clin Invest (2004) 3.38
Mechanism of p38 MAP kinase activation in vivo. Genes Dev (2003) 3.36
T helper cell differentiation: regulation by cis elements and epigenetics. Immunity (2006) 3.33
Chemical genetic analysis of the time course of signal transduction by JNK. Mol Cell (2006) 3.32
Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat Neurosci (2011) 3.27
Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10. Immunity (2008) 3.26
TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci U S A (2004) 3.26
Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo. J Immunol (2010) 3.25
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity (2007) 3.19
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nat Med (2008) 3.15
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science (2012) 3.12
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol (2002) 3.08
Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation. J Immunol (2002) 3.04
Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma. Nat Immunol (2005) 2.96
Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annu Rev Pharmacol Toxicol (2004) 2.94
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proc Natl Acad Sci U S A (2003) 2.94
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J Clin Invest (2008) 2.91
Regulation of the Th2 cytokine locus by a locus control region. Immunity (2003) 2.84
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med (2004) 2.84
A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe (2010) 2.84
An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance. Immunity (2009) 2.82
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med (2002) 2.77
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc Natl Acad Sci U S A (2006) 2.75
Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. J Cell Biol (2005) 2.75
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature (2012) 2.73
The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. Nat Immunol (2009) 2.73
Does Toll-like receptor 3 play a biological role in virus infections? Virology (2004) 2.73
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron (2009) 2.72