PubRank

Zaverio M Ruggeri

Author PubWeight™ 70.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. Proc Natl Acad Sci U S A 2012 3.50
2 Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med 2007 2.85
3 Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nat Med 2005 2.19
4 Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. Proc Natl Acad Sci U S A 2006 2.09
5 Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress. Blood 2006 1.95
6 High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. Blood 2010 1.75
7 Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. Science 2003 1.65
8 The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci U S A 2006 1.62
9 Distinct spatio-temporal Ca2+ signaling elicited by integrin alpha2beta1 and glycoprotein VI under flow. Blood 2009 1.57
10 The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion. Blood 2003 1.56
11 A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo. J Exp Med 2003 1.56
12 Role for ADAP in shear flow-induced platelet mechanotransduction. Blood 2009 1.55
13 Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. Blood 2004 1.55
14 Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition. Circ Cardiovasc Imaging 2012 1.53
15 Functional self-association of von Willebrand factor during platelet adhesion under flow. Proc Natl Acad Sci U S A 2001 1.51
16 Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. Proc Natl Acad Sci U S A 2005 1.51
17 Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus. Proc Natl Acad Sci U S A 2008 1.48
18 Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding. Proc Natl Acad Sci U S A 2003 1.38
19 Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant. Blood 2009 1.36
20 P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J Clin Invest 2011 1.29
21 Size regulation of von Willebrand factor-mediated platelet thrombi by ADAMTS13 in flowing blood. Blood 2005 1.28
22 Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibalpha mechanoreceptor. Blood 2002 1.24
23 Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage. Blood 2009 1.22
24 HBV pathogenesis in animal models: recent advances on the role of platelets. J Hepatol 2007 1.20
25 Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. Blood 2005 1.19
26 Cell damage evaluation of thermal inkjet printed Chinese hamster ovary cells. Biotechnol Bioeng 2010 1.18
27 Neutrophils release brakes of coagulation. Nat Med 2010 1.16
28 The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies. J Clin Invest 2011 1.13
29 Distinct roles of ADP receptors in von Willebrand factor-mediated platelet signaling and activation under high flow. Blood 2004 1.11
30 In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura. Thromb Haemost 2006 1.09
31 Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling. J Am Coll Cardiol 2005 1.06
32 Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. J Biol Chem 2002 1.05
33 Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus. Clin Vaccine Immunol 2007 1.04
34 The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi. Blood 2013 1.03
35 New perspectives on von Willebrand factor functions in hemostasis and thrombosis. Semin Hematol 2005 1.01
36 Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function. Proc Natl Acad Sci U S A 2009 1.01
37 Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. Blood 2011 1.01
38 ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. Blood 2006 1.00
39 Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I. Proc Natl Acad Sci U S A 2011 0.98
40 Platelet mimetic particles for targeting thrombi in flowing blood. Adv Mater 2012 0.98
41 The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice. Blood 2007 0.95
42 Induction of platelet thrombi by bacteria and antibodies. Blood 2002 0.95
43 Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesity. Arterioscler Thromb Vasc Biol 2009 0.94
44 Factor XI interacts with the leucine-rich repeats of glycoprotein Ibalpha on the activated platelet. J Biol Chem 2004 0.93
45 A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Ibalpha for the diagnosis of patients with low von Willebrand factor levels. Haematologica 2004 0.92
46 Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain. Acta Crystallogr D Biol Crystallogr 2004 0.90
47 Platelet and von Willebrand factor interactions at the vessel wall. Hamostaseologie 2004 0.90
48 Comparison of VerifyNow-P2Y12 test and Flow Cytometry for monitoring individual platelet response to clopidogrel. What is the cut-off value for identifying patients who are low responders to clopidogrel therapy? Thromb J 2009 0.88
49 Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. J Clin Invest 2015 0.86
50 Contribution of leptin receptor N-linked glycans to leptin binding. Biochem J 2008 0.86
51 The role of the porcine von Willebrand factor: baboon platelet interactions in pulmonary xenotransplantation. Transplantation 2002 0.82
52 Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties. Arterioscler Thromb Vasc Biol 2013 0.80
53 Structure and function of the von Willebrand factor A1 domain. Curr Protein Pept Sci 2002 0.78
54 Indications for a protective function of beta2-glycoprotein I in thrombotic thrombocytopenic purpura. Br J Haematol 2012 0.78
55 Conditional knockout of integrin α2β1 in murine megakaryocytes leads to reduced mean platelet volume. PLoS One 2013 0.78
56 Altered von Willebrand factor subunit proteolysis and multimer processing associated with the Cys2362Phe mutation in the B2 domain. Thromb Haemost 2007 0.77
57 Tensile destruction test as an estimation of partial proteolysis in fibrin clots. Am J Hematol 2002 0.75
58 A single amino acid change in the binding pocket alters specificity of an anti-integrin antibody AP7.4 as revealed by its crystal structure. Blood Cells Mol Dis 2004 0.75
59 Tailored antiplatelet therapy in a patient with ITP and clopidogrel resistance. Thromb Haemost 2014 0.75