Sidney W Whiteheart

Author PubWeight™ 54.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 AAA+ proteins: have engine, will work. Nat Rev Mol Cell Biol 2005 7.73
2 Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases. J Struct Biol 2004 2.15
3 Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. Mol Biol Cell 2006 2.02
4 Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo. Blood 2009 2.00
5 Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood 2010 2.00
6 A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17. Brain 2006 1.75
7 A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing. Blood 2011 1.61
8 Cellular functions of NSF: not just SNAPs and SNAREs. FEBS Lett 2007 1.42
9 PKCalpha regulates platelet granule secretion and thrombus formation in mice. J Clin Invest 2009 1.41
10 Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion. Blood 2012 1.35
11 Munc18b/STXBP2 is required for platelet secretion. Blood 2012 1.30
12 Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor. J Biol Chem 2004 1.27
13 Phosphorylation of SNAP-23 regulates exocytosis from mast cells. J Biol Chem 2004 1.23
14 Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood 2003 1.18
15 Arf6 plays an early role in platelet activation by collagen and convulxin. Blood 2005 1.12
16 The platelet release reaction: just when you thought platelet secretion was simple. Curr Opin Hematol 2008 1.10
17 Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF). Biochim Biophys Acta 2011 1.08
18 Platelet secretion is kinetically heterogeneous in an agonist-responsive manner. Blood 2012 1.06
19 Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nat Commun 2013 1.05
20 IκB kinase phosphorylation of SNAP-23 controls platelet secretion. Blood 2013 1.03
21 Mast cell degranulation requires N-ethylmaleimide-sensitive factor-mediated SNARE disassembly. J Immunol 2003 1.02
22 Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. J Biol Chem 2011 1.01
23 Dissecting the N-ethylmaleimide-sensitive factor: required elements of the N and D1 domains. J Biol Chem 2009 1.00
24 Application of a Saccharomyces cerevisiae model to study requirements for trafficking of Yersinia pestis YopM in eucaryotic cells. Infect Immun 2003 1.00
25 A role for Sec1/Munc18 proteins in platelet exocytosis. Biochem J 2003 1.00
26 Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation. J Biol Chem 2008 0.97
27 Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm. Epilepsy Res 2006 0.95
28 Uncoupling the ATPase activity of the N-ethylmaleimide sensitive factor (NSF) from 20S complex disassembly. Biochemistry 2002 0.90
29 Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. J Clin Invest 2014 0.89
30 Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly. J Struct Biol 2012 0.89
31 Hexahistidine-tag-specific optical probes for analyses of proteins and their interactions. Anal Biochem 2009 0.87
32 Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes. Epilepsia 2008 0.87
33 The Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation. J Biol Chem 2012 0.85
34 Studies of secretion using permeabilized platelets. Methods Mol Biol 2004 0.82
35 Plasma membrane Ca(2+)-ATPase (PMCA) translocates to filopodia during platelet activation. Thromb Haemost 2004 0.82
36 Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release. Epilepsia 2011 0.81
37 Protein expression in platelets from six species that differ in their open canalicular system. Platelets 2010 0.81
38 Platelets from Munc18c heterozygous mice exhibit normal stimulus-induced release. Thromb Haemost 2004 0.79
39 Platelet activation and its patient-specific consequences. Thromb Res 2007 0.78
40 Murine platelets are not regulated by O-linked beta-N-acetylglucosamine. Arch Biochem Biophys 2008 0.78
41 Histidine-tag-directed chromophores for tracer analyses in the analytical ultracentrifuge. Methods 2010 0.77
42 Demonstration of differential quantitative requirements for NSF among multiple vesicle fusion pathways of GLUT4 using a dominant-negative ATPase-deficient NSF. Biochem Biophys Res Commun 2005 0.77
43 Thiosulfinates modulate platelet activation by reaction with surface free sulfhydryls and internal thiol-containing proteins. Platelets 2007 0.76
44 The ins and outs of endocytic trafficking in platelet functions. Curr Opin Hematol 2017 0.75