AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development.

PubWeight™: 1.86‹?› | Rank: Top 3%

🔗 View Article (PMC 3426120)

Published in Plant Cell on July 05, 2012

Authors

Benjamin Péret1, Kamal Swarup, Alison Ferguson, Malvika Seth, Yaodong Yang, Stijn Dhondt, Nicholas James, Ilda Casimiro, Paula Perry, Adnan Syed, Haibing Yang, Jesica Reemmer, Edward Venison, Caroline Howells, Miguel A Perez-Amador, Jeonga Yun, Jose Alonso, Gerrit T S Beemster, Laurent Laplaze, Angus Murphy, Malcolm J Bennett, Erik Nielsen, Ranjan Swarup

Author Affiliations

1: School of Biosciences and Centre for Plant Integrative Biology, University of Nottingham, LE12 5RD Nottingham, United Kingdom.

Articles citing this

Systems analysis of auxin transport in the Arabidopsis root apex. Plant Cell (2014) 1.87

Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana. PLoS Genet (2015) 1.44

Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence. Proc Natl Acad Sci U S A (2013) 1.38

Systems analysis of shoot apical meristem growth and development: integrating hormonal and mechanical signaling. Plant Cell (2012) 1.31

AUX/LAX family of auxin influx carriers-an overview. Front Plant Sci (2012) 1.16

Auxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID. Elife (2014) 1.15

Auxin reflux between the endodermis and pericycle promotes lateral root initiation. EMBO J (2012) 1.12

Phototropism: growing towards an understanding of plant movement. Plant Cell (2014) 1.08

Patterning of leaf vein networks by convergent auxin transport pathways. PLoS Genet (2013) 0.96

Auxin activity: Past, present, and future. Am J Bot (2015) 0.96

Differential growth at the apical hook: all roads lead to auxin. Front Plant Sci (2013) 0.95

Insights into the origin and evolution of the plant hormone signaling machinery. Plant Physiol (2015) 0.95

The art of being flexible: how to escape from shade, salt, and drought. Plant Physiol (2014) 0.93

ECHIDNA-mediated post-Golgi trafficking of auxin carriers for differential cell elongation. Proc Natl Acad Sci U S A (2013) 0.93

Auxin and cytokinin control formation of the quiescent centre in the adventitious root apex of Arabidopsis. Ann Bot (2013) 0.92

The circadian clock rephases during lateral root organ initiation in Arabidopsis thaliana. Nat Commun (2015) 0.91

The role of auxin transporters in monocots development. Front Plant Sci (2014) 0.90

Arabidopsis SHR and SCR transcription factors and AUX1 auxin influx carrier control the switch between adventitious rooting and xylogenesis in planta and in in vitro cultured thin cell layers. Ann Bot (2015) 0.88

Activation of Big Grain1 significantly improves grain size by regulating auxin transport in rice. Proc Natl Acad Sci U S A (2015) 0.88

Genome-wide identification and expression profiling analysis of ZmPIN, ZmPILS, ZmLAX and ZmABCB auxin transporter gene families in maize (Zea mays L.) under various abiotic stresses. PLoS One (2015) 0.86

Multiple roles for membrane-associated protein trafficking and signaling in gravitropism. Front Plant Sci (2012) 0.85

The oak gene expression atlas: insights into Fagaceae genome evolution and the discovery of genes regulated during bud dormancy release. BMC Genomics (2015) 0.84

Transcriptional Profiles of Drought-Related Genes in Modulating Metabolic Processes and Antioxidant Defenses in Lolium multiflorum. Front Plant Sci (2016) 0.83

Tracing a key player in the regulation of plant architecture: the columnar growth habit of apple trees (Malus × domestica). Planta (2013) 0.83

A Functional Antagonistic Relationship between Auxin and Mitochondrial Retrograde Signaling Regulates Alternative Oxidase1a Expression in Arabidopsis. Plant Physiol (2014) 0.83

Ethylene Inhibits Root Elongation during Alkaline Stress through AUXIN1 and Associated Changes in Auxin Accumulation. Plant Physiol (2015) 0.82

Numerical bifurcation analysis of the pattern formation in a cell based auxin transport model. J Math Biol (2012) 0.81

Auxin Import and Local Auxin Biosynthesis Are Required for Mitotic Divisions, Cell Expansion and Cell Specification during Female Gametophyte Development in Arabidopsis thaliana. PLoS One (2015) 0.81

Genetic control of root growth: from genes to networks. Ann Bot (2015) 0.81

Novel Vein Patterns in Arabidopsis Induced by Small Molecules. Plant Physiol (2015) 0.80

A current perspective on the role of AGCVIII kinases in PIN-mediated apical hook development. Front Plant Sci (2015) 0.80

The exosome and trans-acting small interfering RNAs regulate cuticular wax biosynthesis during Arabidopsis inflorescence stem development. Plant Physiol (2014) 0.80

A strigolactone signal is required for adventitious root formation in rice. Ann Bot (2015) 0.80

Comprehensive Analysis of the Soybean (Glycine max) GmLAX Auxin Transporter Gene Family. Front Plant Sci (2016) 0.79

Auxin Input Pathway Disruptions Are Mitigated by Changes in Auxin Biosynthetic Gene Expression in Arabidopsis. Plant Physiol (2014) 0.79

Arabidopsis aux1rcr1 mutation alters AUXIN RESISTANT1 targeting and prevents expression of the auxin reporter DR5:GUS in the root apex. J Exp Bot (2013) 0.79

Parsimonious Model of Vascular Patterning Links Transverse Hormone Fluxes to Lateral Root Initiation: Auxin Leads the Way, while Cytokinin Levels Out. PLoS Comput Biol (2015) 0.79

The ASH1-RELATED3 SET-domain protein controls cell division competence of the meristem and the quiescent center of the Arabidopsis primary root. Plant Physiol (2014) 0.79

RBOH-mediated ROS production facilitates lateral root emergence in Arabidopsis. Development (2016) 0.78

Lateral Organ Boundaries Domain16 and 18 Act Downstream of the AUXIN1 and LIKE-AUXIN3 Auxin Influx Carriers to Control Lateral Root Development in Arabidopsis. Plant Physiol (2015) 0.78

Transcriptomic analysis reveals the gene expression profile that specifically responds to IBA during adventitious rooting in mung bean seedlings. BMC Genomics (2016) 0.78

Gene Networks Involved in Hormonal Control of Root Development in Arabidopsis thaliana: A Framework for Studying Its Disturbance by Metal Stress. Int J Mol Sci (2015) 0.78

Formation of polarity convergences underlying shoot outgrowths. Elife (2016) 0.78

The Nitrification Inhibitor Methyl 3-(4-Hydroxyphenyl)Propionate Modulates Root Development by Interfering with Auxin Signaling via the NO/ROS Pathway. Plant Physiol (2016) 0.78

Calcium: The Missing Link in Auxin Action. Plants (Basel) (2013) 0.77

Usual and unusual development of the dicot leaf: involvement of transcription factors and hormones. Plant Cell Rep (2013) 0.77

Modelling the dynamics of polar auxin transport in inflorescence stems of Arabidopsis thaliana. J Exp Bot (2015) 0.77

The Shape of an Auxin Pulse, and What It Tells Us about the Transport Mechanism. PLoS Comput Biol (2015) 0.77

Evolution of Cis-Regulatory Elements and Regulatory Networks in Duplicated Genes of Arabidopsis. Plant Physiol (2015) 0.77

Auxin influx importers modulate serration along the leaf margin. Plant J (2015) 0.76

A 2,4-dichlorophenoxyacetic acid analog screened using a maize coleoptile system potentially inhibits indole-3-acetic acid influx in Arabidopsis thaliana. Plant Signal Behav (2014) 0.76

SHADE AVOIDANCE 4 is Required for Proper Auxin Distribution in the Hypocotyl. Plant Physiol (2016) 0.75

An auxin influx transporter regulates vascular patterning in cotyledons. Plant Cell (2012) 0.75

A recovery principle provides insight into auxin pattern control in the Arabidopsis root. Sci Rep (2017) 0.75

Transcription of TIR1-Controlled Genes Can be Regulated within 10 Min by an Auxin-Induced Process. Can TIR1 be the Receptor? Front Plant Sci (2016) 0.75

Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root. Development (2016) 0.75

Comprehensive Analysis and Expression Profiling of the OsLAX and OsABCB Auxin Transporter Gene Families in Rice (Oryza sativa) under Phytohormone Stimuli and Abiotic Stresses. Front Plant Sci (2016) 0.75

A Genome-Scale Analysis of the PIN Gene Family Reveals Its Functions in Cotton Fiber Development. Front Plant Sci (2017) 0.75

Ectopic KNOX Expression Affects Plant Development by Altering Tissue Cell Polarity and Identity. Plant Cell (2016) 0.75

Genome-wide analysis of auxin transport genes identifies the hormone responsive patterns associated with leafy head formation in Chinese cabbage. Sci Rep (2017) 0.75

Transcriptional changes during ovule development in two genotypes of litchi (Litchi chinensis Sonn.) with contrast in seed size. Sci Rep (2016) 0.75

MtLAX2, a Functional Homologue of the Arabidopsis Auxin Influx Transporter AUX1, Is Required for Nodule Organogenesis. Plant Physiol (2017) 0.75

Genome-wide identification and expression analysis of ClLAX, ClPIN and ClABCB genes families in Citrullus lanatus under various abiotic stresses and grafting. BMC Genet (2017) 0.75

Arabidopsis seed germination speed is controlled by SNL histone deacetylase-binding factor-mediated regulation of AUX1. Nat Commun (2016) 0.75

Control of vein patterning by intracellular auxin transport. Plant Signal Behav (2013) 0.75

Dynamic PIN-FORMED auxin efflux carrier phosphorylation at the plasma membrane controls auxin efflux-dependent growth. Proc Natl Acad Sci U S A (2017) 0.75

Modeling halotropism: a key role for root tip architecture and reflux loop remodeling in redistributing auxin. Development (2016) 0.75

Q&A: Auxin: the plant molecule that influences almost anything. BMC Biol (2016) 0.75

Spatiotemporal expression patterns of wheat amino acid transporters reveal their putative roles in nitrogen transport and responses to abiotic stress. Sci Rep (2017) 0.75

Lanthanum Inhibits Primary Root Growth by Repressing Auxin Carrier Abundances in Arabidopsis. Front Plant Sci (2017) 0.75

Articles cited by this

Regulation of phyllotaxis by polar auxin transport. Nature (2003) 9.17

Arabidopsis AUX1 gene: a permease-like regulator of root gravitropism. Science (1996) 6.52

PIN proteins perform a rate-limiting function in cellular auxin efflux. Science (2006) 5.58

Auxin: a trigger for change in plant development. Cell (2009) 5.28

Polar PIN localization directs auxin flow in plants. Science (2006) 4.81

Functional redundancy of PIN proteins is accompanied by auxin-dependent cross-regulation of PIN expression. Development (2005) 4.14

Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apex. Genes Dev (2001) 3.89

The auxin influx carrier LAX3 promotes lateral root emergence. Nat Cell Biol (2008) 3.69

Root gravitropism requires lateral root cap and epidermal cells for transport and response to a mobile auxin signal. Nat Cell Biol (2005) 3.61

Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1. Plant J (2005) 3.04

AUX1 promotes lateral root formation by facilitating indole-3-acetic acid distribution between sink and source tissues in the Arabidopsis seedling. Plant Cell (2002) 2.95

Auxin transport routes in plant development. Development (2009) 2.91

The evolutionary dynamics of plant duplicate genes. Curr Opin Plant Biol (2005) 2.63

Molecular and cellular aspects of auxin-transport-mediated development. Trends Plant Sci (2007) 2.56

Structure-function analysis of the presumptive Arabidopsis auxin permease AUX1. Plant Cell (2004) 2.55

AXR4 is required for localization of the auxin influx facilitator AUX1. Science (2006) 2.49

High-affinity auxin transport by the AUX1 influx carrier protein. Curr Biol (2006) 2.45

A toolkit and robust pipeline for the generation of fosmid-based reporter genes in C. elegans. PLoS One (2009) 2.18

Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell (2006) 2.08

Auxin transport through non-hair cells sustains root-hair development. Nat Cell Biol (2008) 1.94

Auxin influx carriers stabilize phyllotactic patterning. Genes Dev (2008) 1.92

GABI-Kat SimpleSearch: new features of the Arabidopsis thaliana T-DNA mutant database. Nucleic Acids Res (2011) 1.86

Functional expression and characterization of Arabidopsis ABCB, AUX 1 and PIN auxin transporters in Schizosaccharomyces pombe. Plant J (2009) 1.63

P-glycoprotein4 displays auxin efflux transporter-like action in Arabidopsis root hair cells and tobacco cells. Plant Cell (2007) 1.62

The amino acid/auxin:proton symport permease family. Biochim Biophys Acta (1999) 1.43

Cell polarity signaling in Arabidopsis involves a BFA-sensitive auxin influx pathway. Curr Biol (2002) 1.41

The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings. Development (2010) 1.39

Auxin influx activity is associated with Frankia infection during actinorhizal nodule formation in Casuarina glauca. Plant Physiol (2007) 1.28

A recombineering-based gene tagging system for Arabidopsis. Plant J (2011) 1.07

Vascular patterning: more than just auxin? Curr Biol (2003) 0.94

The binding of auxin to the Arabidopsis auxin influx transporter AUX1. Plant Physiol (2008) 0.92

Articles by these authors

TAA1-mediated auxin biosynthesis is essential for hormone crosstalk and plant development. Cell (2008) 5.26

Arabidopsis H+-PPase AVP1 regulates auxin-mediated organ development. Science (2005) 4.14

The auxin influx carrier LAX3 promotes lateral root emergence. Nat Cell Biol (2008) 3.69

Root gravitropism requires lateral root cap and epidermal cells for transport and response to a mobile auxin signal. Nat Cell Biol (2005) 3.61

Dissecting Arabidopsis lateral root development. Trends Plant Sci (2003) 3.52

Auxin-dependent regulation of lateral root positioning in the basal meristem of Arabidopsis. Development (2007) 3.31

Chloroplast to nucleus communication triggered by accumulation of Mg-protoporphyrinIX. Nature (2003) 3.27

Ethylene upregulates auxin biosynthesis in Arabidopsis seedlings to enhance inhibition of root cell elongation. Plant Cell (2007) 3.14

Arabidopsis lateral root development: an emerging story. Trends Plant Sci (2009) 3.08

AUX1 promotes lateral root formation by facilitating indole-3-acetic acid distribution between sink and source tissues in the Arabidopsis seedling. Plant Cell (2002) 2.95

Multilevel interactions between ethylene and auxin in Arabidopsis roots. Plant Cell (2007) 2.90

Control of proliferation, endoreduplication and differentiation by the Arabidopsis E2Fa-DPa transcription factor. EMBO J (2002) 2.90

Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial. J Clin Oncol (2009) 2.88

A novel sensor to map auxin response and distribution at high spatio-temporal resolution. Nature (2012) 2.86

Plant neurobiology: no brain, no gain? Trends Plant Sci (2007) 2.83

A novel aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity. Curr Biol (2010) 2.81

Plant ABC proteins--a unified nomenclature and updated inventory. Trends Plant Sci (2008) 2.81

High-throughput quantification of root growth using a novel image-analysis tool. Plant Physiol (2009) 2.78

Changes in gene expression in Arabidopsis shoots during phosphate starvation and the potential for developing smart plants. Plant Physiol (2003) 2.73

Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome. Cell (2007) 2.58

Structure-function analysis of the presumptive Arabidopsis auxin permease AUX1. Plant Cell (2004) 2.55

Colocalization of fluorescent markers in confocal microscope images of plant cells. Nat Protoc (2008) 2.53

Divergent evolution of duplicate genes leads to genetic incompatibilities within A. thaliana. Science (2009) 2.52

Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so-gradual process. Dev Cell (2012) 2.49

Analysis of the small GTPase gene superfamily of Arabidopsis. Plant Physiol (2003) 2.45

High-affinity auxin transport by the AUX1 influx carrier protein. Curr Biol (2006) 2.45

Cytokinins act directly on lateral root founder cells to inhibit root initiation. Plant Cell (2007) 2.23

Cell cycle progression in the pericycle is not sufficient for SOLITARY ROOT/IAA14-mediated lateral root initiation in Arabidopsis thaliana. Plant Cell (2005) 2.23

The plant-specific cyclin-dependent kinase CDKB1;1 and transcription factor E2Fa-DPa control the balance of mitotically dividing and endoreduplicating cells in Arabidopsis. Plant Cell (2004) 2.20

Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell (2006) 2.08

Speeding up the evaluation of new agents in cancer. J Natl Cancer Inst (2008) 2.08

The Arabidopsis Rab GTPase RabA4b localizes to the tips of growing root hair cells. Plant Cell (2004) 2.06

Lateral root development in Arabidopsis: fifty shades of auxin. Trends Plant Sci (2013) 1.97

Auxin transport through non-hair cells sustains root-hair development. Nat Cell Biol (2008) 1.94

Auxin influx carriers stabilize phyllotactic patterning. Genes Dev (2008) 1.92

Auxin transporters--why so many? Cold Spring Harb Perspect Biol (2010) 1.92

Cell numbers and leaf development in Arabidopsis: a functional analysis of the STRUWWELPETER gene. EMBO J (2002) 1.92

Root growth in Arabidopsis requires gibberellin/DELLA signalling in the endodermis. Nat Cell Biol (2008) 1.89

Systems analysis of auxin transport in the Arabidopsis root apex. Plant Cell (2014) 1.87

The VTI family of SNARE proteins is necessary for plant viability and mediates different protein transport pathways. Plant Cell (2003) 1.85

Genome-wide identification of potential plant E2F target genes. Plant Physiol (2005) 1.85

Gibberellin signaling controls cell proliferation rate in Arabidopsis. Curr Biol (2009) 1.82

The Arabidopsis YUCCA1 flavin monooxygenase functions in the indole-3-pyruvic acid branch of auxin biosynthesis. Plant Cell (2011) 1.81

Interferon alfa-2a versus combination therapy with interferon alfa-2a, interleukin-2, and fluorouracil in patients with untreated metastatic renal cell carcinoma (MRC RE04/EORTC GU 30012): an open-label randomised trial. Lancet (2010) 1.81

Bimodular auxin response controls organogenesis in Arabidopsis. Proc Natl Acad Sci U S A (2010) 1.78

Auxin transport: a field in flux. Trends Plant Sci (2006) 1.78

A role for the RabA4b effector protein PI-4Kbeta1 in polarized expansion of root hair cells in Arabidopsis thaliana. J Cell Biol (2006) 1.77

ABCB19/PGP19 stabilises PIN1 in membrane microdomains in Arabidopsis. Plant J (2008) 1.74

Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling. Chem Biol (2009) 1.73

The Arabidopsis AAA ATPase SKD1 is involved in multivesicular endosome function and interacts with its positive regulator LYST-INTERACTING PROTEIN5. Plant Cell (2007) 1.70

A role for peroxisomes in photomorphogenesis and development of Arabidopsis. Science (2002) 1.67

Lateral root emergence: a difficult birth. J Exp Bot (2009) 1.64

Brassinosteroid perception in the epidermis controls root meristem size. Development (2011) 1.62

Gibberellin signaling in the endodermis controls Arabidopsis root meristem size. Curr Biol (2009) 1.62

The DP-E2F-like gene DEL1 controls the endocycle in Arabidopsis thaliana. Curr Biol (2005) 1.61

Marking cell lineages in living tissues. Plant J (2005) 1.61

RootNav: navigating images of complex root architectures. Plant Physiol (2013) 1.61

Rho-GTPase-dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth. J Cell Biol (2008) 1.59

A local maximum in gibberellin levels regulates maize leaf growth by spatial control of cell division. Curr Biol (2012) 1.57

Survival and growth of Arabidopsis plants given limited water are not equal. Nat Biotechnol (2011) 1.52

Actin-based motility of endosomes is linked to the polar tip growth of root hairs. Eur J Cell Biol (2005) 1.52

The plant-specific family of DNA-binding proteins containing three HMG-box domains interacts with mitotic and meiotic chromosomes. New Phytol (2011) 1.48

Diarch symmetry of the vascular bundle in Arabidopsis root encompasses the pericycle and is reflected in distich lateral root initiation. Plant Physiol (2007) 1.48

Endodermal ABA signaling promotes lateral root quiescence during salt stress in Arabidopsis seedlings. Plant Cell (2013) 1.46

Probing the reproducibility of leaf growth and molecular phenotypes: a comparison of three Arabidopsis accessions cultivated in ten laboratories. Plant Physiol (2010) 1.46

Increased leaf size: different means to an end. Plant Physiol (2010) 1.45

The Arabidopsis thaliana homolog of yeast BRE1 has a function in cell cycle regulation during early leaf and root growth. Plant Cell (2007) 1.45