Eric C Beyer

Author PubWeight™ 45.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev 2003 4.87
2 Cardiac gap junction channels show quantitative differences in selectivity. Circ Res 2002 2.28
3 Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation. Circ Res 2002 1.54
4 Oxidative stress, lens gap junctions, and cataracts. Antioxid Redox Signal 2009 1.49
5 Loss of function and impaired degradation of a cataract-associated mutant connexin50. Eur J Cell Biol 2003 1.48
6 A mutant connexin50 with enhanced hemichannel function leads to cell death. Invest Ophthalmol Vis Sci 2009 1.43
7 Connexin43 and connexin26 form gap junctions, but not heteromeric channels in co-expressing cells. J Cell Sci 2004 1.40
8 Pathways for degradation of connexins and gap junctions. Cardiovasc Res 2004 1.38
9 Amino terminal glutamate residues confer spermine sensitivity and affect voltage gating and channel conductance of rat connexin40 gap junctions. J Physiol 2004 1.37
10 An aberrant sequence in a connexin46 mutant underlies congenital cataracts. J Biol Chem 2005 1.22
11 Autophagy: a pathway that contributes to connexin degradation. J Cell Sci 2011 1.17
12 Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels. J Gen Physiol 2004 1.13
13 Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5. Cardiovasc Res 2004 1.11
14 Connexin40 and connexin43 determine gating properties of atrial gap junction channels. J Mol Cell Cardiol 2009 1.05
15 Dynamic model for ventricular junctional conductance during the cardiac action potential. Am J Physiol Heart Circ Physiol 2004 1.05
16 Redistribution of connexin45 in gap junctions of connexin43-deficient hearts. Cardiovasc Res 2002 1.03
17 Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50. Am J Physiol Cell Physiol 2011 1.02
18 N-terminal residues in Cx43 and Cx40 determine physiological properties of gap junction channels, but do not influence heteromeric assembly with each other or with Cx26. J Cell Sci 2006 1.01
19 Cataracts are caused by alterations of a critical N-terminal positive charge in connexin50. Invest Ophthalmol Vis Sci 2008 1.01
20 An intact connexin N-terminus is required for function but not gap junction formation. J Cell Sci 2008 0.95
21 Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces. J Biol Chem 2011 0.94
22 An MIP/AQP0 mutation with impaired trafficking and function underlies an autosomal dominant congenital lamellar cataract. Exp Eye Res 2012 0.93
23 Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Mol Biol Cell 2012 0.92
24 Connexin43 increases the sensitivity of prostate cancer cells to TNFalpha-induced apoptosis. J Cell Sci 2007 0.92
25 Cx30.2 can form heteromeric gap junction channels with other cardiac connexins. Biochem Biophys Res Commun 2008 0.92
26 A connexin50 mutant, CX50fs, that causes cataracts is unstable, but is rescued by a proteasomal inhibitor. J Biol Chem 2013 0.92
27 Transgenic overexpression of connexin50 induces cataracts. Exp Eye Res 2007 0.90
28 Cytoplasmic amino acids within the membrane interface region influence connexin oligomerization. J Membr Biol 2012 0.89
29 Different domains are critical for oligomerization compatibility of different connexins. Biochem J 2011 0.89
30 Connexin50D47A decreases levels of fiber cell connexins and impairs lens fiber cell differentiation. Invest Ophthalmol Vis Sci 2013 0.89
31 Connexin43 with a cytoplasmic loop deletion inhibits the function of several connexins. Biochem Biophys Res Commun 2005 0.88
32 The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation. Mol Vis 2009 0.87
33 The N terminus of connexin37 contains an alpha-helix that is required for channel function. J Biol Chem 2009 0.87
34 The cytoplasmic accumulations of the cataract-associated mutant, Connexin50P88S, are long-lived and form in the endoplasmic reticulum. Exp Eye Res 2008 0.85
35 Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis. Biochem Biophys Res Commun 2004 0.84
36 Highly restricted pattern of connexin36 expression in chick somite development. Anat Embryol (Berl) 2004 0.82
37 A carboxyl terminal domain of connexin43 is critical for gap junction plaque formation but not for homo- or hetero-oligomerization. Cell Commun Adhes 2003 0.82
38 c-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmias. Cardiovasc Res 2012 0.80
39 Inducible coexpression of connexin37 or connexin40 with connexin43 selectively affects intercellular molecular transfer. J Membr Biol 2012 0.78
40 The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating. J Membr Biol 2014 0.76