Published in Curr Top Med Chem on January 01, 2012
Inauhzin sensitizes p53-dependent cytotoxicity and tumor suppression of chemotherapeutic agents. Neoplasia (2013) 0.96
Measurement of DNA concentration as a normalization strategy for metabolomic data from adherent cell lines. Anal Chem (2013) 0.91
Clinical significance of a point mutation in DNA polymerase beta (POLB) gene in gastric cancer. Int J Biol Sci (2015) 0.85
Loss of urokinase receptor sensitizes cells to DNA damage and delays DNA repair. PLoS One (2014) 0.80
The pharmacogenomics of osteosarcoma. Pharmacogenomics J (2016) 0.79
Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle (2013) 0.78
Conformational determinants for the recruitment of ERCC1 by XPA in the nucleotide excision repair (NER) Pathway: structure and dynamics of the XPA binding motif. Biophys J (2013) 0.78
Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair. PLoS One (2013) 0.77
Irreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesion. J Am Chem Soc (2014) 0.77
A novel assay revealed that ribonucleotide reductase is functionally important for interstrand DNA crosslink repair. Bioorg Med Chem (2015) 0.76
Review and application of group theory to molecular systems biology. Theor Biol Med Model (2011) 2.00
Analytic theories of allometric scaling. J Exp Biol (2011) 1.14
Molecular signaling network complexity is correlated with cancer patient survivability. Proc Natl Acad Sci U S A (2012) 1.13
A biopolymer transistor: electrical amplification by microtubules. Biophys J (2006) 1.05
Cytoskeletal signaling: is memory encoded in microtubule lattices by CaMKII phosphorylation? PLoS Comput Biol (2012) 1.03
The zinc dyshomeostasis hypothesis of Alzheimer's disease. PLoS One (2012) 1.02
Cancer as a dynamical phase transition. Theor Biol Med Model (2011) 1.01
The roles of beta-tubulin mutations and isotype expression in acquired drug resistance. Cancer Inform (2007) 0.98
Transitions in microtubule C-termini conformations as a possible dendritic signaling phenomenon. Eur Biophys J (2005) 0.96
An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis. Theor Biol Med Model (2013) 0.95
Neural cytoskeleton capabilities for learning and memory. J Biol Phys (2010) 0.93
Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction. PLoS One (2012) 0.92
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives. Mol Cancer (2010) 0.91
Cancer proliferation and therapy: the Warburg effect and quantum metabolism. Theor Biol Med Model (2010) 0.91
Chemotherapy drugs form ion pores in membranes due to physical interactions with lipids. Chem Biol Drug Des (2012) 0.89
Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity. J Chem Inf Model (2009) 0.88
Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression. AIP Adv (2012) 0.88
Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing. J Mol Graph Model (2008) 0.86
Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia. PLoS One (2012) 0.86
Microtubule ionic conduction and its implications for higher cognitive functions. J Integr Neurosci (2010) 0.85
Quantum effects in the understanding of consciousness. J Integr Neurosci (2014) 0.85
Homology modeling of tubulin: influence predictions for microtubule's biophysical properties. Eur Biophys J (2006) 0.85
Determination of the optimal tubulin isotype target as a method for the development of individualized cancer chemotherapy. Theor Biol Med Model (2013) 0.84
A Refined Model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes. J Chem Inf Model (2014) 0.83
Emission of mitochondrial biophotons and their effect on electrical activity of membrane via microtubules. J Integr Neurosci (2011) 0.82
A computationally designed DNA aptamer template with specific binding to phosphatidylserine. Nucleic Acid Ther (2013) 0.82
Ensemble-based virtual screening reveals dual-inhibitors for the p53-MDM2/MDMX interactions. J Mol Graph Model (2009) 0.81
Viscous drag effect in the flexural rigidity and cantilever stiffness of bio- and nano-filaments measured with the shooting-bead method. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.81
Self-organization and entropy reduction in a living cell. Biosystems (2012) 0.81
Entropic fragment-based approach to aptamer design. Chem Biol Drug Des (2011) 0.80
Molecular dynamics modeling of tubulin C-terminal tail interactions with the microtubule surface. Proteins (2011) 0.80
Vibrational dynamics of bio- and nano-filaments in viscous solution subjected to ultrasound: implications for microtubules. Eur Biophys J (2011) 0.80
Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length. Cell Physiol Biochem (2015) 0.80
Stochastic and Deterministic Models of Cellular p53 Regulation. Front Oncol (2013) 0.80
DNA polymerase beta (pol β) inhibitors: a comprehensive overview. Drug Discov Today (2012) 0.79
Computational design and biological testing of highly cytotoxic colchicine ring A modifications. Chem Biol Drug Des (2010) 0.79
Improving the performance of the coupled reference interaction site model-hyper-netted chain (RISM-HNC)/simulation method for free energy of solvation. J Phys Chem B (2008) 0.79
Microtubule assembly of isotypically purified tubulin and its mixtures. Biophys J (2008) 0.79
Determination of noscapine's localization and interaction with the tubulin-α/β heterodimer. Chem Biol Drug Des (2011) 0.79
Rayleigh instability of the inverted one-cell amphibian embryo. Phys Biol (2008) 0.78
Effect of calcium on electrical energy transfer by microtubules. J Biol Phys (2008) 0.78
Quantitative analysis of the conservation of the tertiary structure of protein segments. Protein J (2006) 0.78
Model of ionic currents through microtubule nanopores and the lumen. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 0.78
Geometrical comparison of two protein structures using Wigner-D functions. Proteins (2014) 0.78
Simulation of the effects of microtubules in the cortical rotation of amphibian embryos in normal and zero gravity. Biosystems (2012) 0.78
Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45. PLoS One (2012) 0.78
Discovery of small molecule inhibitors that interact with γ-tubulin. Chem Biol Drug Des (2012) 0.77
Experimental and computational study of the interaction of novel colchicinoids with a recombinant human αI/βI-tubulin heterodimer. Chem Biol Drug Des (2013) 0.77
Near death experiences: a multidisciplinary hypothesis. Front Hum Neurosci (2013) 0.77
Computable features required to evaluate the efficacy of drugs and a universal algorithm to find optimally effective drug in a drug complex. PLoS One (2012) 0.77
The molecular mechanism of action of the CR6261-Azichromycin combination found through computational analysis. PLoS One (2012) 0.77
Interactomes, manufacturomes and relational biology: analogies between systems biology and manufacturing systems. Theor Biol Med Model (2011) 0.77
An accurate method for prediction of protein-ligand binding site on protein surface using SVM and statistical depth function. Biomed Res Int (2013) 0.77
Keeping time: could quantum beating in microtubules be the basis for the neural synchrony related to consciousness? J Integr Neurosci (2014) 0.77
Dynamic change of heme environment in soluble guanylate cyclase and complexation of NO-independent drug agents with H-NOX domain. Chem Biol Drug Des (2012) 0.76
Explicitly solvated ligand contribution to continuum solvation models for binding free energies: selectivity of theophylline binding to an RNA aptamer. J Phys Chem B (2010) 0.76
Analysis of protein three-dimension structure using amino acids depths. Protein J (2007) 0.76
A critical assessment of the information processing capabilities of neuronal microtubules using coherent excitations. J Biol Phys (2010) 0.76
Modeling the yew tree tubulin and a comparison of its interaction with paclitaxel to human tubulin. Pharm Res (2012) 0.75
Homology and molecular dynamics models of toll-like receptor 7 protein and its dimerization. Chem Biol Drug Des (2014) 0.75
Computer assisted design of second-generation colchicine derivatives. Interdiscip Sci (2010) 0.75
Electrostatic contributions to colchicine binding within tubulin isotypes. Electromagn Biol Med (2009) 0.75
Peloruside, laulimalide, and noscapine interactions with beta-tubulin. Pharm Res (2012) 0.75
Modelling DNA Repair Pathways: Recent Advances and Future Directions. Curr Pharm Des (2016) 0.75
Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism. J Med Chem (2016) 0.75
QM and QM/MD simulations of the Vinca alkaloids docked to tubulin. J Mol Graph Model (2011) 0.75
An investigation of the plausibility of stochastic resonance in tubulin dimers. Biosystems (2011) 0.75
Self-assembled ligands targeting TLR7: a molecular level investigation. Langmuir (2017) 0.75