Jack A Tuszynski

Author PubWeight™ 51.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Review and application of group theory to molecular systems biology. Theor Biol Med Model 2011 2.00
2 Analytic theories of allometric scaling. J Exp Biol 2011 1.14
3 Molecular signaling network complexity is correlated with cancer patient survivability. Proc Natl Acad Sci U S A 2012 1.13
4 A biopolymer transistor: electrical amplification by microtubules. Biophys J 2006 1.05
5 Cytoskeletal signaling: is memory encoded in microtubule lattices by CaMKII phosphorylation? PLoS Comput Biol 2012 1.03
6 The zinc dyshomeostasis hypothesis of Alzheimer's disease. PLoS One 2012 1.02
7 Cancer as a dynamical phase transition. Theor Biol Med Model 2011 1.01
8 The roles of beta-tubulin mutations and isotype expression in acquired drug resistance. Cancer Inform 2007 0.98
9 Transitions in microtubule C-termini conformations as a possible dendritic signaling phenomenon. Eur Biophys J 2005 0.96
10 An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis. Theor Biol Med Model 2013 0.95
11 Neural cytoskeleton capabilities for learning and memory. J Biol Phys 2010 0.93
12 Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction. PLoS One 2012 0.92
13 Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives. Mol Cancer 2010 0.91
14 Cancer proliferation and therapy: the Warburg effect and quantum metabolism. Theor Biol Med Model 2010 0.91
15 Chemotherapy drugs form ion pores in membranes due to physical interactions with lipids. Chem Biol Drug Des 2012 0.89
16 DNA repair inhibitors: the next major step to improve cancer therapy. Curr Top Med Chem 2012 0.89
17 Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity. J Chem Inf Model 2009 0.88
18 Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression. AIP Adv 2012 0.88
19 Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing. J Mol Graph Model 2008 0.86
20 Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia. PLoS One 2012 0.86
21 Microtubule ionic conduction and its implications for higher cognitive functions. J Integr Neurosci 2010 0.85
22 Homology modeling of tubulin: influence predictions for microtubule's biophysical properties. Eur Biophys J 2006 0.85
23 Quantum effects in the understanding of consciousness. J Integr Neurosci 2014 0.85
24 Determination of the optimal tubulin isotype target as a method for the development of individualized cancer chemotherapy. Theor Biol Med Model 2013 0.84
25 A Refined Model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes. J Chem Inf Model 2014 0.83
26 Emission of mitochondrial biophotons and their effect on electrical activity of membrane via microtubules. J Integr Neurosci 2011 0.82
27 A computationally designed DNA aptamer template with specific binding to phosphatidylserine. Nucleic Acid Ther 2013 0.82
28 Self-organization and entropy reduction in a living cell. Biosystems 2012 0.81
29 Viscous drag effect in the flexural rigidity and cantilever stiffness of bio- and nano-filaments measured with the shooting-bead method. Phys Rev E Stat Nonlin Soft Matter Phys 2009 0.81
30 Entropic fragment-based approach to aptamer design. Chem Biol Drug Des 2011 0.80
31 Vibrational dynamics of bio- and nano-filaments in viscous solution subjected to ultrasound: implications for microtubules. Eur Biophys J 2011 0.80
32 Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length. Cell Physiol Biochem 2015 0.80
33 Molecular dynamics modeling of tubulin C-terminal tail interactions with the microtubule surface. Proteins 2011 0.80
34 Stochastic and Deterministic Models of Cellular p53 Regulation. Front Oncol 2013 0.80
35 DNA polymerase beta (pol β) inhibitors: a comprehensive overview. Drug Discov Today 2012 0.79
36 Computational design and biological testing of highly cytotoxic colchicine ring A modifications. Chem Biol Drug Des 2010 0.79
37 Determination of noscapine's localization and interaction with the tubulin-α/β heterodimer. Chem Biol Drug Des 2011 0.79
38 Microtubule assembly of isotypically purified tubulin and its mixtures. Biophys J 2008 0.79
39 Improving the performance of the coupled reference interaction site model-hyper-netted chain (RISM-HNC)/simulation method for free energy of solvation. J Phys Chem B 2008 0.79
40 Rayleigh instability of the inverted one-cell amphibian embryo. Phys Biol 2008 0.78
41 Model of ionic currents through microtubule nanopores and the lumen. Phys Rev E Stat Nonlin Soft Matter Phys 2010 0.78
42 Geometrical comparison of two protein structures using Wigner-D functions. Proteins 2014 0.78
43 Simulation of the effects of microtubules in the cortical rotation of amphibian embryos in normal and zero gravity. Biosystems 2012 0.78
44 Effect of calcium on electrical energy transfer by microtubules. J Biol Phys 2008 0.78
45 Quantitative analysis of the conservation of the tertiary structure of protein segments. Protein J 2006 0.78
46 Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45. PLoS One 2012 0.78
47 Experimental and computational study of the interaction of novel colchicinoids with a recombinant human αI/βI-tubulin heterodimer. Chem Biol Drug Des 2013 0.77
48 Interactomes, manufacturomes and relational biology: analogies between systems biology and manufacturing systems. Theor Biol Med Model 2011 0.77
49 Computable features required to evaluate the efficacy of drugs and a universal algorithm to find optimally effective drug in a drug complex. PLoS One 2012 0.77
50 An accurate method for prediction of protein-ligand binding site on protein surface using SVM and statistical depth function. Biomed Res Int 2013 0.77
51 Keeping time: could quantum beating in microtubules be the basis for the neural synchrony related to consciousness? J Integr Neurosci 2014 0.77
52 Near death experiences: a multidisciplinary hypothesis. Front Hum Neurosci 2013 0.77
53 The molecular mechanism of action of the CR6261-Azichromycin combination found through computational analysis. PLoS One 2012 0.77
54 Discovery of small molecule inhibitors that interact with γ-tubulin. Chem Biol Drug Des 2012 0.77
55 Dynamic change of heme environment in soluble guanylate cyclase and complexation of NO-independent drug agents with H-NOX domain. Chem Biol Drug Des 2012 0.76
56 A critical assessment of the information processing capabilities of neuronal microtubules using coherent excitations. J Biol Phys 2010 0.76
57 Explicitly solvated ligand contribution to continuum solvation models for binding free energies: selectivity of theophylline binding to an RNA aptamer. J Phys Chem B 2010 0.76
58 Analysis of protein three-dimension structure using amino acids depths. Protein J 2007 0.76
59 Computer assisted design of second-generation colchicine derivatives. Interdiscip Sci 2010 0.75
60 Homology and molecular dynamics models of toll-like receptor 7 protein and its dimerization. Chem Biol Drug Des 2014 0.75
61 Electrostatic contributions to colchicine binding within tubulin isotypes. Electromagn Biol Med 2009 0.75
62 QM and QM/MD simulations of the Vinca alkaloids docked to tubulin. J Mol Graph Model 2011 0.75
63 Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism. J Med Chem 2016 0.75
64 Self-assembled ligands targeting TLR7: a molecular level investigation. Langmuir 2017 0.75
65 Modelling DNA Repair Pathways: Recent Advances and Future Directions. Curr Pharm Des 2016 0.75
66 An investigation of the plausibility of stochastic resonance in tubulin dimers. Biosystems 2011 0.75
67 Peloruside, laulimalide, and noscapine interactions with beta-tubulin. Pharm Res 2012 0.75