Published in Methods on July 14, 2012
Sequencing and validation of housekeeping genes for quantitative real-time PCR during the gonadotrophic cycle of Diploptera punctata. BMC Res Notes (2013) 0.81
Capturing drug responses by quantitative promoter activity profiling. CPT Pharmacometrics Syst Pharmacol (2013) 0.75
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell (2003) 3.66
A probability-based approach for the analysis of large-scale RNAi screens. Nat Methods (2007) 3.34
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha. Cardiovasc Res (2007) 3.31
Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Nat Struct Mol Biol (2004) 2.70
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res (2010) 2.06
Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors. J Clin Oncol (2012) 2.04
Research-based PAM50 subtype predictor identifies higher responses and improved survival outcomes in HER2-positive breast cancer in the NOAH study. Clin Cancer Res (2014) 1.86
Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells. Clin Cancer Res (2003) 1.82
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.79
Expression profiling of human immune cell subsets identifies miRNA-mRNA regulatory relationships correlated with cell type specific expression. PLoS One (2012) 1.76
Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Res (2002) 1.62
Laparoscopic treatment of endometrial cancer: systematic review. J Minim Invasive Gynecol (2013) 1.54
Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling. J Biol Chem (2003) 1.39
Meta-analysis of human leukocyte antigen genetic polymorphisms and susceptibility to chronic myelogenous leukemia in Chinese population. Leuk Res (2011) 1.38
Reverse transcriptase-polymerase chain reaction based quantification of the combined MDS-EVI1/EVI1 gene in acute myeloid leukemia. Leuk Lymphoma (2006) 1.37
An expanding universe of small proteins. Curr Opin Microbiol (2011) 1.35
Massive parallel bisulfite sequencing of CG-rich DNA fragments reveals that methylation of many X-chromosomal CpG islands in female blood DNA is incomplete. Hum Mol Genet (2009) 1.34
New score predicting for prognosis in PML-RARA+, AML1-ETO+, or CBFBMYH11+ acute myeloid leukemia based on quantification of fusion transcripts. Blood (2003) 1.31
The ADH1B Arg47His polymorphism in east Asian populations and expansion of rice domestication in history. BMC Evol Biol (2010) 1.30
Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia. Am J Hum Genet (2009) 1.29
Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations. BMC Biol (2008) 1.27
RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export. Mol Cell Biol (2004) 1.26
Crystal synthesis and effects of epitaxial perovskite manganite underlayer conditions on characteristics of ZnO nanostructured heterostructures. Nanoscale (2013) 1.26
Intratumoral cytokines/chemokines/growth factors and tumor infiltrating dendritic cells: friends or enemies? Cancer Metastasis Rev (2006) 1.24
Nanoscale crystal imperfection-induced characterization changes of manganite nanolayers with various crystallographic textures. Nanoscale Res Lett (2013) 1.23
Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the tibetan plateau. Mol Biol Evol (2013) 1.22
Nuclear export of mRNA by TAP/NXF1 requires two nucleoporin-binding sites but not p15. Mol Cell Biol (2002) 1.18
Insights into effective RNAi gained from large-scale siRNA validation screening. Oligonucleotides (2007) 1.16
Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy (2014) 1.14
Metabolic flux engineering of L-lysine production in Corynebacterium glutamicum--over expression and modification of G6P dehydrogenase. J Biotechnol (2007) 1.12
Dendritic cells combining with cytokine-induced killer cells synergize chemotherapy in patients with late-stage non-small cell lung cancer. Cancer Immunol Immunother (2011) 1.10
The prevalence and causes of visual impairment in an elderly Chinese Bai ethnic rural population: the Yunnan minority eye study. Invest Ophthalmol Vis Sci (2012) 1.09
Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance. Proc Natl Acad Sci U S A (2012) 1.07
An optimized workflow for improved gene expression profiling for formalin-fixed, paraffin-embedded tumor samples. J Clin Bioinforma (2013) 1.05
Polymer single-nanowire optical sensors. Nano Lett (2008) 1.05
Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross. PLoS One (2010) 1.04
In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials. Mol Cancer Ther (2006) 1.02
High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the γ-secretase inhibitor, RO4929097. Mol Oncol (2011) 1.02
Identification and validation of genes affecting aortic lesions in mice. J Clin Invest (2010) 1.02
Effects of pirfenidone on proliferation, migration, and collagen contraction of human Tenon's fibroblasts in vitro. Invest Ophthalmol Vis Sci (2009) 0.99
Significant expansion of exon-bordering protein domains during animal proteome evolution. Nucleic Acids Res (2005) 0.99
Meta-analysis of inter-species liver co-expression networks elucidates traits associated with common human diseases. PLoS Comput Biol (2009) 0.99
Real-time contrast-enhanced ultrasonography of resected and immunohistochemically proven hepatic angiomyolipomas. Abdom Imaging (2010) 0.99
[Risk factors associated with continued heroin use during methadone maintenance treatment in Guizhou province, China]. Zhonghua Yu Fang Yi Xue Za Zhi (2008) 0.96
Dampened activity of E2F1-DP and Myb-MuvB transcription factors in Drosophila endocycling cells. J Cell Sci (2010) 0.95
Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients. Blood (2013) 0.95
Biological evaluation of a multi-targeted small molecule inhibitor of tumor-induced angiogenesis. Bioorg Med Chem Lett (2006) 0.95
RO4383596, an orally active KDR, FGFR, and PDGFR inhibitor: synthesis and biological evaluation. Bioorg Med Chem (2005) 0.94
Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes. EMBO J (2002) 0.94
Effect of FCGR2A and FCGR3A variants on CLL outcome. Blood (2010) 0.93
Co-degradation with glucose of four surfactants, CTAB, Triton X-100, SDS and Rhamnolipid, in liquid culture media and compost matrix. Biodegradation (2006) 0.93
A prospective study of the efficacy of a combination of autologous dendritic cells, cytokine-induced killer cells, and chemotherapy in advanced non-small cell lung cancer patients. Tumour Biol (2013) 0.92
Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma. Med Oncol (2015) 0.91
Genetic evidence of an East Asian origin and paleolithic northward migration of Y-chromosome haplogroup N. PLoS One (2013) 0.90
Single-cell analysis by electrochemical detection with a microfluidic device. J Chromatogr A (2005) 0.90
Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus. Am J Epidemiol (2012) 0.89
Content-based histopathology image retrieval using CometCloud. BMC Bioinformatics (2014) 0.89
Fast detection of humidity with a subwavelength-diameter fiber taper coated with gelatin film. Opt Express (2008) 0.89
Second intron of mouse nestin gene directs its expression in pluripotent embryonic carcinoma cells through POU factor binding site. Acta Biochim Biophys Sin (Shanghai) (2006) 0.88
Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors. Bioorg Med Chem Lett (2008) 0.87
Enrichment of human prostate cancer cells with tumor initiating properties in mouse and zebrafish xenografts by differential adhesion. Prostate (2013) 0.86
High-throughput single-cell analysis for enzyme activity without cytolysis. Anal Chem (2006) 0.86
MYCN transgenic zebrafish model with the characterization of acute myeloid leukemia and altered hematopoiesis. PLoS One (2013) 0.86
Coalition of DNA polymorphisms of ApoB and ApoAI genes is related with coronary artery disease in Kazaks. J Geriatr Cardiol (2012) 0.86
Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients. Int J Cancer (2014) 0.86
CD45RA-Foxp3high but not CD45RA+Foxp3low suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression. J Exp Clin Cancer Res (2014) 0.85
Negative pressure pinched sample injection for microchip-based electrophoresis. Lab Chip (2006) 0.85
[Impact of methadone maintenance treatment on HIV risk behaviors of heroin drug users]. Zhonghua Yu Fang Yi Xue Za Zhi (2010) 0.84
Dynamic enhancing vascular pattern of intrahepatic peripheral cholangiocarcinoma on contrast-enhanced ultrasound: the influence of chronic hepatitis and cirrhosis. Abdom Imaging (2013) 0.84
RG7212 anti-TWEAK mAb inhibits tumor growth through inhibition of tumor cell proliferation and survival signaling and by enhancing the host antitumor immune response. Clin Cancer Res (2013) 0.84
Associations between tumor necrosis factor-α polymorphisms and risk of psoriasis: a meta-analysis. PLoS One (2013) 0.84
Adsorption of surfactants on a Pseudomonas aeruginosa strain and the effect on cell surface lypohydrophilic property. Appl Microbiol Biotechnol (2007) 0.84
Identification and classification of chemicals using terahertz reflective spectroscopic focal-plane imaging system. Opt Express (2006) 0.84
Pharmacokinetics of pirfenidone after topical administration in rabbit eye. Mol Vis (2011) 0.84
Detection of a novel reactive metabolite of diclofenac: evidence for CYP2C9-mediated bioactivation via arene oxides. Drug Metab Dispos (2005) 0.84
Dibenzoylmethane, a natural dietary compound, induces HIF-1 alpha and increases expression of VEGF. Biochem Biophys Res Commun (2003) 0.84
Reliability and validity of addiction severity index in drug users with methadone maintenance treatment in Guizhou province, China. Biomed Environ Sci (2008) 0.84
Regulatory dendritic cells: new targets for cancer immunotherapy. Cancer Biol Ther (2011) 0.83
Effect of dirhamnolipid on the removal of phenol catalyzed by laccase in aqueous solution. World J Microbiol Biotechnol (2011) 0.83
Association of TGF-beta1 gene polymorphisms in exon1 and blood levels with essential hypertension. Blood Press (2010) 0.82
Pyrazolobenzodiazepines: part I. Synthesis and SAR of a potent class of kinase inhibitors. Bioorg Med Chem Lett (2010) 0.82
Tryptophan hydroxylase 2 gene is associated with major depressive disorder in a female Chinese population. J Affect Disord (2011) 0.82
Prevalence and outcomes of cataract surgery in adult rural Chinese populations of the Bai nationality in Dali: the Yunnan minority eye study. PLoS One (2013) 0.82
Expression of δNp73 in hippocampus of APP/PS1 transgenic mice following GFP-BMSCs transplantation. Neurol Res (2011) 0.82
Influence of laparoscopic gastrectomy on the detection rate of free gastric cancer cells in the peritoneal cavity. Ann Surg Oncol (2009) 0.82
Prevalence of circulating CD4+CD28null T cells is associated with early atherosclerotic damage in patients with end-stage renal disease undergoing hemodialysis. Hum Immunol (2012) 0.82
Increased levels of IL-23 and osteopontin in serum and cerebrospinal fluid of multiple sclerosis patients. J Neuroimmunol (2012) 0.81
[Factors influencing the rate on retention to methadone maintenance treatment program among heroin addicts in Guizhou, China]. Zhonghua Liu Xing Bing Xue Za Zhi (2009) 0.81
Effects of HIF-1alpha on human gastric cancer cell apoptosis at different CO(2) pressures. Clin Exp Med (2008) 0.81