Published in Mol Cell Biol on August 01, 2002
REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol (2002) 2.55
Flexible gates: dynamic topologies and functions for FG nucleoporins in nucleocytoplasmic transport. Eukaryot Cell (2009) 1.81
Nuclear export dynamics of RNA-protein complexes. Nature (2011) 1.63
Crystal structure of the Drosophila Mago nashi-Y14 complex. Genes Dev (2003) 1.36
RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export. Mol Cell Biol (2004) 1.26
mRNA export from mammalian cell nuclei is dependent on GANP. Curr Biol (2009) 1.11
RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA. Nucleic Acids Res (2006) 1.09
Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1. Nucleic Acids Res (2010) 1.08
Nuclear export of metazoan replication-dependent histone mRNAs is dependent on RNA length and is mediated by TAP. RNA (2005) 1.06
Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15. EMBO Rep (2003) 1.06
NXT2 is required for embryonic heart development in zebrafish. BMC Dev Biol (2005) 1.06
Identification and characterization of the mouse nuclear export factor (Nxf) family members. Nucleic Acids Res (2005) 0.98
Karyopherin beta 2B participates in mRNA export from the nucleus. Proc Natl Acad Sci U S A (2002) 0.95
Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs. Nucleic Acids Res (2007) 0.91
Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP. Nucleic Acids Res (2014) 0.89
Optical microwell assay of membrane transport kinetics. Biophys J (2003) 0.86
Export of adenoviral late mRNA from the nucleus requires the Nxf1/Tap export receptor. J Virol (2010) 0.83
Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export. Viruses (2013) 0.82
The SR protein B52/SRp55 is required for DNA topoisomerase I recruitment to chromatin, mRNA release and transcription shutdown. PLoS Genet (2010) 0.81
Multiple Export Mechanisms for mRNAs. Cells (2015) 0.80
Nuclear export of messenger RNA. Genes (Basel) (2015) 0.80
The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold. J Mol Biol (2011) 0.80
NTF2-like domain of Tap plays a critical role in cargo mRNA recognition and export. Nucleic Acids Res (2015) 0.79
GANP enhances the efficiency of mRNA nuclear export in mammalian cells. Nucleus (2011) 0.79
The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA. Nucleic Acids Res (2015) 0.79
Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes. PLoS One (2012) 0.79
A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs. Nucleic Acids Res (2016) 0.78
Dm nxf1/sbr gene affects the formation of meiotic spindle in female Drosophila melanogaster. Chromosome Res (2009) 0.76
Three-Dimensional Mapping of mRNA Export through the Nuclear Pore Complex. Genes (Basel) (2014) 0.76
Nucleocytoplasmic transport: the soluble phase. Annu Rev Biochem (1998) 10.74
Transport of proteins and RNAs in and out of the nucleus. Cell (1999) 6.02
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol Cell (1998) 5.85
Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores. EMBO J (1997) 5.61
Kinetic analysis of translocation through nuclear pore complexes. EMBO J (2001) 5.27
Nuclear export of different classes of RNA is mediated by specific factors. J Cell Biol (1994) 4.99
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J (1999) 4.49
Splicing is required for rapid and efficient mRNA export in metazoans. Proc Natl Acad Sci U S A (1999) 4.26
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA (2000) 3.96
Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell (2000) 3.33
The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes Dev (1999) 3.24
The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway. EMBO J (1997) 3.10
Nucleocytoplasmic transport enters the atomic age. Curr Opin Cell Biol (2001) 3.06
The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export. Curr Biol (1997) 2.90
TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus. EMBO J (1999) 2.83
The nuclear pore complex: a protein machine bridging the nucleus and cytoplasm. Curr Opin Cell Biol (2000) 2.56
Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export. J Cell Biol (2000) 2.48
The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain. EMBO J (2000) 2.44
Minimal Rev-response element for type 1 human immunodeficiency virus. J Virol (1991) 2.22
Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor. Mol Cell (2001) 2.17
Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs. Mol Cell Biol (1999) 2.09
TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. Mol Cell Biol (2000) 2.07
NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila. RNA (2001) 2.04
Domains of U4 and U6 snRNAs required for snRNP assembly and splicing complementation in Xenopus oocytes. EMBO J (1990) 1.96
Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. Mol Cell Biol (2002) 1.86
Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export. J Biol Chem (2001) 1.84
Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP. J Mol Biol (1999) 1.77
Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran. J Mol Biol (1998) 1.63
Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export. Mol Cell Biol (1999) 1.60
The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p. RNA (2000) 1.52
NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells. Mol Cell Biol (2001) 1.44
Two closely related human nuclear export factors utilize entirely distinct export pathways. Mol Cell (2001) 1.43
Small bristles, the Drosophila ortholog of NXF-1, is essential for mRNA export throughout development. RNA (2001) 1.32
Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1. Nat Struct Biol (2002) 1.24
NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation. Curr Biol (2001) 1.22
Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins. EMBO Rep (2000) 1.22
Mex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA export. Mol Cell Biol (2000) 1.12
RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex. J Biol Chem (2001) 1.11
Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling. J Biol Chem (2001) 1.09
Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element. J Virol (2000) 1.07
NXT1 is necessary for the terminal step of Crm1-mediated nuclear export. J Cell Biol (2001) 1.06
RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro. Mol Cell Biol (2000) 1.03
Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet (2011) 9.79
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev (2006) 8.78
P bodies: at the crossroads of post-transcriptional pathways. Nat Rev Mol Cell Biol (2007) 7.96
Getting to the root of miRNA-mediated gene silencing. Cell (2008) 7.17
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat Struct Mol Biol (2008) 5.57
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA (2005) 5.15
Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain. Nature (2003) 4.92
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol (2007) 4.90
Transcriptome complexity in a genome-reduced bacterium. Science (2009) 4.64
Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species. Curr Opin Cell Biol (2005) 4.45
Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat Struct Mol Biol (2004) 4.38
Deadenylation is a widespread effect of miRNA regulation. RNA (2008) 3.98
Proteome organization in a genome-reduced bacterium. Science (2009) 3.97
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes Dev (2007) 3.92
Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Mol Cell Biol (2006) 3.80
Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways. EMBO J (2003) 3.68
Impact of genome reduction on bacterial metabolism and its regulation. Science (2009) 3.45
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome. RNA (2005) 3.11
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. Mol Cell (2004) 3.05
An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature (2004) 2.95
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Mol Cell (2011) 2.80
Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila. Nature (2004) 2.80
SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Mol Cell (2005) 2.71
Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Nat Struct Mol Biol (2004) 2.70
The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nat Struct Mol Biol (2004) 2.65
Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets. RNA (2005) 2.59
REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol (2002) 2.55
SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA (2008) 2.54
The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing. RNA (2009) 2.37
The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Nat Struct Mol Biol (2004) 2.36
The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release. Mol Cell Biol (2009) 2.28
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature (2005) 2.27
mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons. FEBS Lett (2007) 2.22
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. EMBO J (2006) 2.16
A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay. EMBO J (2007) 2.11
A novel mode of RBD-protein recognition in the Y14-Mago complex. Nat Struct Biol (2003) 2.11
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins. RNA (2009) 2.11
A C-terminal silencing domain in GW182 is essential for miRNA function. RNA (2009) 2.10
Nonsense-mediated mRNA decay: Target genes and functional diversification of effectors. Trends Biochem Sci (2006) 2.07
The interplay of nuclear mRNP assembly, mRNA surveillance and export. Trends Cell Biol (2003) 2.03
An efficient protein complex purification method for functional proteomics in higher eukaryotes. Nat Biotechnol (2002) 1.71
Genome-wide analysis of nuclear mRNA export pathways in Drosophila. EMBO J (2003) 1.70
Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. EMBO J (2010) 1.64
The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition. EMBO Rep (2005) 1.63
Complex genomic rearrangements lead to novel primate gene function. Genome Res (2005) 1.62
Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein. Proc Natl Acad Sci U S A (2011) 1.56
Quality control of gene expression: a stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay. Genes Dev (2006) 1.51
Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. PLoS Genet (2009) 1.46
Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Mol Cell Biol (2009) 1.44
Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Mol Cell (2009) 1.43
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Nucleic Acids Res (2009) 1.42
Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein. EMBO Rep (2010) 1.39
Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu. Nat Rev Mol Cell Biol (2010) 1.36
The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex. EMBO J (2011) 1.29
The role of disordered protein regions in the assembly of decapping complexes and RNP granules. Genes Dev (2013) 1.29
RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export. Mol Cell Biol (2004) 1.26
Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction. Mol Cell (2012) 1.24
A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. Mol Cell Biol (2007) 1.23
HPat provides a link between deadenylation and decapping in metazoa. J Cell Biol (2010) 1.23
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes. Mol Cell Biol (2008) 1.22
The yeast ski complex: crystal structure and RNA channeling to the exosome complex. Cell (2013) 1.20
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex. Nucleic Acids Res (2012) 1.19
GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation. EMBO J (2013) 1.17
CUP promotes deadenylation and inhibits decapping of mRNA targets. Genes Dev (2011) 1.14
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Nat Struct Mol Biol (2012) 1.13
The role of GW182 proteins in miRNA-mediated gene silencing. Adv Exp Med Biol (2013) 1.13
Metabolic flux engineering of L-lysine production in Corynebacterium glutamicum--over expression and modification of G6P dehydrogenase. J Biotechnol (2007) 1.12
Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex. EMBO Rep (2004) 1.09
NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain. RNA Biol (2013) 1.09
DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Proc Natl Acad Sci U S A (2009) 1.08
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev (2010) 1.08
The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets. Nucleic Acids Res (2012) 1.07
The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2. Genes Dev (2013) 1.07
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression. Genes Dev (2014) 1.04
The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Nucleic Acids Res (2012) 1.03
The C-terminal region of Ge-1 presents conserved structural features required for P-body localization. RNA (2008) 1.02
Structure and assembly of the NOT module of the human CCR4-NOT complex. Nat Struct Mol Biol (2013) 1.02
The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa. EMBO J (2010) 1.00
The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome. RNA (2011) 0.99
An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay. Genes Dev (2013) 0.99
The PAM domain, a multi-protein complex-associated module with an all-alpha-helix fold. BMC Bioinformatics (2003) 0.97
A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs. Cold Spring Harb Perspect Biol (2012) 0.97
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins. Mol Cell (2013) 0.95
Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes. EMBO J (2002) 0.94
Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat Struct Mol Biol (2011) 0.93
miRISC recruits decapping factors to miRNA targets to enhance their degradation. Nucleic Acids Res (2013) 0.93
The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1. Nucleic Acids Res (2014) 0.92
NMR assignment of the Drosophila Argonaute2 PAZ domain. J Biomol NMR (2004) 0.91
RNAi: finding the elusive endonuclease. RNA (2004) 0.88
A role for eIF4AII in microRNA-mediated mRNA silencing. Nat Struct Mol Biol (2013) 0.79
Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays. Methods (2012) 0.79
Making sense of nonsense. Nat Struct Mol Biol (2013) 0.77
Directing mRNA export. Nat Struct Mol Biol (2004) 0.77
A tiny helper lightens the maternal load. Cell (2006) 0.77
Delving into the diversity of silencing pathways. Symposium on MicroRNAs and siRNAs: biological functions and mechanisms. EMBO Rep (2007) 0.75
Nucleus and gene expression. Curr Opin Cell Biol (2009) 0.75