BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors.

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Published in Cancer Discov on July 13, 2012

Authors

Kimberly Brown Dahlman1, Junfeng Xia, Katherine Hutchinson, Charles Ng, Donald Hucks, Peilin Jia, Mohammad Atefi, Zengliu Su, Suzanne Branch, Pamela L Lyle, Donna J Hicks, Viviana Bozon, John A Glaspy, Neal Rosen, David B Solit, James L Netterville, Cindy L Vnencak-Jones, Jeffrey A Sosman, Antoni Ribas, Zhongming Zhao, William Pao

Author Affiliations

1: Vanderbilt-Ingram Cancer Center, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

Associated clinical trials:

Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies | NCT00948467

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