PubRank

Raymond C Stevens

Author PubWeight™ 312.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 2007 20.32
2 GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science 2007 11.74
3 The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 2008 11.74
4 Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 2010 10.30
5 Structure of an agonist-bound human A2A adenosine receptor. Science 2011 6.21
6 A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure 2008 6.01
7 Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A 2002 6.00
8 Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 2010 5.86
9 Structure of the human κ-opioid receptor in complex with JDTic. Nature 2012 5.18
10 Structure-function of the G protein-coupled receptor superfamily. Annu Rev Pharmacol Toxicol 2012 3.83
11 Crystal structure of a lipid G protein-coupled receptor. Science 2012 3.78
12 Serial femtosecond crystallography of G protein-coupled receptors. Science 2013 3.58
13 Structure of the human histamine H1 receptor complex with doxepin. Nature 2011 3.48
14 Structural basis for allosteric regulation of GPCRs by sodium ions. Science 2012 3.40
15 Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science 2013 3.17
16 Structure of the human smoothened receptor bound to an antitumour agent. Nature 2013 3.08
17 Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. Science 2012 3.07
18 Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature 2012 2.96
19 Microscale fluorescent thermal stability assay for membrane proteins. Structure 2008 2.95
20 Diversity and modularity of G protein-coupled receptor structures. Trends Pharmacol Sci 2011 2.89
21 Structure of the human glucagon class B G-protein-coupled receptor. Nature 2013 2.86
22 Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem Biol 2009 2.82
23 Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. J R Soc Interface 2009 2.69
24 Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin. Nat Biotechnol 2006 2.66
25 Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. J Am Chem Soc 2010 2.62
26 Structural features for functional selectivity at serotonin receptors. Science 2013 2.60
27 Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3. Structure 2005 2.55
28 Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling. Science 2002 2.50
29 Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature 2008 2.36
30 Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Proc Natl Acad Sci U S A 2006 2.28
31 Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008. Nat Rev Drug Discov 2009 2.23
32 Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure 2011 2.11
33 Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure 2012 2.08
34 Discovery of new GPCR biology: one receptor structure at a time. Structure 2009 2.08
35 Automated sample mounting and alignment system for biological crystallography at a synchrotron source. Structure 2004 2.00
36 Structural basis of cell surface receptor recognition by botulinum neurotoxin B. Nature 2006 1.97
37 Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome. Acta Crystallogr D Biol Crystallogr 2003 1.92
38 Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem 2010 1.88
39 Structural basis for molecular recognition at serotonin receptors. Science 2013 1.86
40 Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR. Cell 2013 1.83
41 Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Science 2014 1.81
42 Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS. Proc Natl Acad Sci U S A 2004 1.70
43 Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure. J Mol Biol 2007 1.63
44 Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin. Biochemistry 2002 1.59
45 A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4. J Mol Biol 2006 1.59
46 Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl 2007 1.55
47 Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX. Structure 2011 1.54
48 Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction. PLoS Pathog 2008 1.54
49 Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold. Proteins 2006 1.51
50 Structural plasticity and the evolution of antibody affinity and specificity. J Mol Biol 2003 1.47
51 Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution. Proteins 2002 1.45
52 Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. Angew Chem Int Ed Engl 2006 1.45
53 In situ data collection and structure refinement from microcapillary protein crystallization. J Appl Crystallogr 2005 1.42
54 Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc Natl Acad Sci U S A 2008 1.41
55 Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics. J Mol Biol 2004 1.40
56 The crystal structure of the α-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function. Structure 2011 1.39
57 Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange. Anal Chem 2010 1.38
58 Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues. J Biol Chem 2010 1.37
59 Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog. J Mol Biol 2007 1.35
60 The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases. Structure 2005 1.33
61 In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels. Acta Crystallogr D Biol Crystallogr 2008 1.32
62 Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor. J Med Chem 2011 1.30
63 Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screens. Methods 2004 1.30
64 Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc Natl Acad Sci U S A 2004 1.28
65 Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets. Methods Mol Biol 2010 1.27
66 Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3. J Virol 2008 1.27
67 Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs. J Virol 2006 1.24
68 NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline. Proc Natl Acad Sci U S A 2005 1.23
69 Sphingosine-1-phosphate and its receptors: structure, signaling, and influence. Annu Rev Biochem 2013 1.20
70 Mechanisms underlying responsiveness to tetrahydrobiopterin in mild phenylketonuria mutations. Hum Mutat 2004 1.19
71 Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. ACS Chem Biol 2012 1.19
72 Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures. J Am Chem Soc 2009 1.18
73 Microscale NMR screening of new detergents for membrane protein structural biology. J Am Chem Soc 2008 1.18
74 Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein. J Virol 2007 1.18
75 Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution. Proteins 2004 1.17
76 The genesis of high-throughput structure-based drug discovery using protein crystallography. Curr Opin Chem Biol 2002 1.17
77 Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR. J Struct Funct Genomics 2005 1.13
78 LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophys J 2010 1.13
79 Molecular genetics of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency. Hum Mutat 2008 1.13
80 Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria. Proc Natl Acad Sci U S A 2008 1.10
81 A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. J Mol Biol 2010 1.10
82 GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods 2011 1.09
83 Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation. J Mol Biol 2010 1.09
84 Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution. Proteins 2004 1.09
85 The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex. J Mol Biol 2005 1.08
86 LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Cryst Growth Des 2008 1.08
87 Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch. J Virol 2007 1.08
88 Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates. J Mol Biol 2002 1.08
89 Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus. J Virol 2007 1.07
90 Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc Natl Acad Sci U S A 2013 1.06
91 Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Cryst Growth Des 2011 1.06
92 Scalable high-throughput micro-expression device for recombinant proteins. Biotechniques 2004 1.05
93 Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol 2013 1.05
94 Structural commonalities among integral membrane enzymes. FEBS Lett 2004 1.05
95 Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7. J Virol 2005 1.04
96 A fully integrated protein crystallization platform for small-molecule drug discovery. J Struct Biol 2003 1.04
97 Shotgun crystallization strategy for structural genomics II: crystallization conditions that produce high resolution structures for T. maritima proteins. J Struct Funct Genomics 2005 1.03
98 Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution. Proteins 2006 1.03
99 Structure of botulinum neurotoxin type D light chain at 1.65 A resolution: repercussions for VAMP-2 substrate specificity. Biochemistry 2006 1.02
100 Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition. Biochemistry 2005 1.02
101 Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222. Appl Environ Microbiol 2011 1.02
102 Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. Protein Expr Purif 2007 1.01
103 Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Mol Genet Metab 2005 1.00
104 Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes. Biochemistry 2008 1.00
105 Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution. Proteins 2004 1.00
106 Robotics for automated crystal formation and analysis. Methods Enzymol 2003 1.00
107 Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold. Proteins 2005 0.99
108 Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics. Methods Mol Biol 2008 0.96
109 Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor. J Med Chem 2011 0.96
110 Retraction: Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. Nat Struct Mol Biol 2009 0.95
111 Structural and biochemical characterization of the therapeutic Anabaena variabilis phenylalanine ammonia lyase. J Mol Biol 2008 0.95
112 Chemotype-selective modes of action of κ-opioid receptor agonists. J Biol Chem 2013 0.95
113 FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A. Proteins 2010 0.95
114 The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor. Structure 2013 0.95
115 Engineered nanostructured β-sheet peptides protect membrane proteins. Nat Methods 2013 0.95
116 X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase. J Med Chem 2010 0.93
117 Development of pegylated forms of recombinant Rhodosporidium toruloides phenylalanine ammonia-lyase for the treatment of classical phenylketonuria. Mol Ther 2005 0.93
118 Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. J Membr Biol 2008 0.93
119 Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Mol Pharmacol 2013 0.93
120 Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding. J Mol Biol 2010 0.93
121 Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening. J Med Chem 2012 0.93
122 Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution. Proteins 2004 0.92
123 Crystallization Optimum Solubility Screening: using crystallization results to identify the optimal buffer for protein crystal formation. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.92
124 Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution. Proteins 2004 0.92
125 β₂-adrenergic receptor activation by agonists studied with ¹⁹F NMR spectroscopy. Angew Chem Int Ed Engl 2013 0.92
126 Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). PLoS Pathog 2013 0.91
127 Response of patients with phenylketonuria in the US to tetrahydrobiopterin. Mol Genet Metab 2005 0.91
128 Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor. Proteins 2005 0.91
129 Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. J Biol Chem 2012 0.91
130 Converting an injectable protein therapeutic into an oral form: phenylalanine ammonia lyase for phenylketonuria. Mol Genet Metab 2010 0.89
131 Trends in enzyme therapy for phenylketonuria. Mol Ther 2004 0.89
132 Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins 2004 0.89
133 Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution. Proteins 2004 0.89
134 Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution. Proteins 2006 0.89
135 Structural evidence for substrate strain in antibody catalysis. Proc Natl Acad Sci U S A 2003 0.89
136 Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 A resolution. Proteins 2004 0.88
137 Biopterin responsive phenylalanine hydroxylase deficiency. Genet Med 2004 0.88
138 Toward PKU enzyme replacement therapy: PEGylation with activity retention for three forms of recombinant phenylalanine hydroxylase. Mol Ther 2004 0.88
139 Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold. Proteins 2006 0.88
140 Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution. Proteins 2004 0.87
141 Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution. Proteins 2004 0.87
142 Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p. Proteins 2006 0.87
143 Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. J Med Chem 2011 0.87
144 Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold. Proteins 2005 0.86
145 Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes. ACS Chem Biol 2014 0.86
146 Structure-based epitope and PEGylation sites mapping of phenylalanine ammonia-lyase for enzyme substitution treatment of phenylketonuria. Mol Genet Metab 2007 0.86
147 Opportunities for functional selectivity in GPCR antibodies. Biochem Pharmacol 2012 0.86
148 Structural aspects of therapeutic enzymes to treat metabolic disorders. Hum Mutat 2009 0.86
149 β2-Adrenergic receptor solutions for structural biology analyzed with microscale NMR diffusion measurements. Angew Chem Int Ed Engl 2012 0.86
150 Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold. Proteins 2005 0.85
151 Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution. Proteins 2004 0.85
152 Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 A resolution. Proteins 2005 0.85
153 Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution. Proteins 2003 0.84
154 Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold. Proteins 2006 0.84
155 Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution. Proteins 2005 0.84
156 Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase. J Am Chem Soc 2011 0.84
157 Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. J Am Chem Soc 2013 0.84
158 Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution. Proteins 2004 0.84
159 A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption/Ionization on Silicon (DIOS) platform. Chembiochem 2004 0.84
160 Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26. Langmuir 2010 0.84
161 Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution. Proteins 2004 0.83
162 Structural studies on phenylalanine hydroxylase and implications toward understanding and treating phenylketonuria. Pediatrics 2003 0.83
163 Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution. Proteins 2005 0.83
164 Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site. Proteins 2006 0.82
165 Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution. Proteins 2004 0.82
166 A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer. Methods Mol Biol 2013 0.82
167 Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution. Proteins 2004 0.82
168 Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution. Proteins 2006 0.82
169 Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution. Proteins 2006 0.82
170 Structural characterization of three novel hydroxamate-based zinc chelating inhibitors of the Clostridium botulinum serotype A neurotoxin light chain metalloprotease reveals a compact binding site resulting from 60/70 loop flexibility. Biochemistry 2011 0.82
171 Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase. Bioorg Med Chem Lett 2008 0.81
172 Growth and excitement in membrane protein structural biology. Curr Opin Struct Biol 2010 0.81
173 Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution. Proteins 2004 0.81
174 Mutations in the regulatory domain of phenylalanine hydroxylase and response to tetrahydrobiopterin. Genet Test 2007 0.81
175 Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold. Proteins 2005 0.80
176 RAMP-ing up class-B GPCR ECD structural coverage. Structure 2010 0.80
177 Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution. Proteins 2006 0.80
178 Evaluation of orally administered PEGylated phenylalanine ammonia lyase in mice for the treatment of Phenylketonuria. Mol Genet Metab 2011 0.79
179 Rescue of misfolded proteins and stabilization by small molecules. Methods Mol Biol 2010 0.79
180 Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 A resolution. Proteins 2003 0.79
181 Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution. Proteins 2006 0.79
182 Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77-A resolution. Proteins 2004 0.78
183 Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution. Proteins 2004 0.77
184 Trapping small caffeine in a large GPCR pocket. Structure 2011 0.77
185 Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold. Proteins 2005 0.77
186 Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution. Proteins 2004 0.77
187 A roadmap to membrane protein structures. Methods 2012 0.76
188 Chaperone-like therapy with tetrahydrobiopterin in clinical trials for phenylketonuria: is genotype a predictor of response? JIMD Rep 2011 0.76
189 Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information. J Comput Aided Mol Des 2015 0.76
190 Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies. Langmuir 2012 0.76
191 Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold. Proteins 2004 0.75
192 Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold. Proteins 2005 0.75
193 Morphological manipulation of bolaamphiphilic polydiacetylene assemblies by controlled lipid doping. Chem Phys Lipids 2002 0.75
194 Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution. Proteins 2008 0.75
195 Asia growth in membrane protein structure. Curr Opin Struct Biol 2013 0.75
196 Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution. Proteins 2004 0.75