PubRank

Philippe I H Bastiaens

Author PubWeight™ 71.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 2005 5.99
2 Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature 2013 5.04
3 Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Nat Cell Biol 2007 4.75
4 Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum. Science 2002 3.12
5 Protein analysis on a proteomic scale. Nature 2003 3.12
6 Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling. Nat Cell Biol 2007 2.91
7 The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell 2010 2.72
8 EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation. Nat Cell Biol 2003 2.49
9 Small-molecule inhibition of APT1 affects Ras localization and signaling. Nat Chem Biol 2010 2.37
10 Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat Chem Biol 2011 2.00
11 Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron 2009 1.96
12 The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins. Nat Cell Biol 2011 1.87
13 Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. Curr Opin Cell Biol 2006 1.64
14 Spatial organization of intracellular communication: insights from imaging. Nat Rev Mol Cell Biol 2010 1.55
15 Imaging activation of two Ras isoforms simultaneously in a single cell. Chembiochem 2005 1.54
16 Recruitment of Eph receptors into signaling clusters does not require ephrin contact. J Cell Biol 2004 1.52
17 Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B. Science 2007 1.36
18 In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays. Nat Methods 2010 1.34
19 Signaling from the living plasma membrane. Cell 2011 1.29
20 Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin. EMBO J 2007 1.18
21 Imaging phosphorylation dynamics of the epidermal growth factor receptor. J Biol Chem 2004 1.16
22 Cdt1 interactions in the licensing process: a model for dynamic spatiotemporal control of licensing. Cell Cycle 2007 1.10
23 Imaging in situ protein-DNA interactions in the cell nucleus using FRET-FLIM. Exp Cell Res 2005 1.06
24 Red-edge anisotropy microscopy enables dynamic imaging of homo-FRET between green fluorescent proteins in cells. J Struct Biol 2004 1.04
25 Quantitative microscopy and systems biology: seeing the whole picture. Histochem Cell Biol 2008 1.02
26 VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells. Am J Physiol Cell Physiol 2009 1.00
27 Regulation of Ras localization by acylation enables a mode of intracellular signal propagation. Sci Signal 2010 0.96
28 Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues. J Biol Chem 2005 0.95
29 Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design. Angew Chem Int Ed Engl 2011 0.95
30 Reverse engineering intracellular biochemical networks. Nat Chem Biol 2008 0.92
31 Spatial aspects of intracellular information processing. Curr Opin Genet Dev 2010 0.91
32 siRNA cell arrays for high-content screening microscopy. Biotechniques 2004 0.90
33 Quantitative imaging of apoptosis commitment in colorectal tumor cells. Differentiation 2007 0.86
34 Lateral phosphorylation propagation: an aspect of feedback signalling? Nat Rev Mol Cell Biol 2003 0.84
35 Fluorescence fluctuations of quantum-dot sensors capture intracellular protein interaction dynamics. Nat Methods 2010 0.84
36 A protein-interaction array inside a living cell. Angew Chem Int Ed Engl 2013 0.82
37 Imaging protein-protein interactions by Fluorescence Resonance Energy Transfer (FRET) microscopy. Curr Protoc Neurosci 2006 0.80
38 Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery. Chembiochem 2012 0.79
39 Imaging protein interactions by FRET microscopy: FRET measurements by acceptor photobleaching. CSH Protoc 2006 0.79
40 Measuring FRET by sensitized emission. CSH Protoc 2006 0.79
41 Configurable low-cost plotter device for fabrication of multi-color sub-cellular scale microarrays. Small 2014 0.78
42 High-throughput quantification of posttranslational modifications in situ by CA-FLIM. Methods Enzymol 2011 0.77
43 Cell cycle-dependent binding modes of the ran exchange factor RCC1 to chromatin. Biophys J 2013 0.76
44 Imaging protein interactions by FRET microscopy: FLIM measurements. CSH Protoc 2006 0.76
45 Optimizing cell arrays for accurate functional genomics. BMC Res Notes 2012 0.75
46 Measuring FRET by acceptor photobleaching. CSH Protoc 2006 0.75
47 Imaging protein interactions by FRET microscopy: FRET measurements by sensitized emission. CSH Protoc 2006 0.75
48 FLIM measurements and frequency domain FLIM data analysis. CSH Protoc 2006 0.75
49 Quantifying cellular dynamics by fluorescence resonance energy transfer (FRET) microscopy. Curr Protoc Neurosci 2013 0.75
50 An experimental setup for frequency domain FLIM. CSH Protoc 2006 0.75
51 Imaging protein interactions by FRET microscopy: labeling proteins with fluorescent dyes. CSH Protoc 2006 0.75
52 Imaging protein interactions by FRET microscopy: cell preparation for FRET analysis. CSH Protoc 2006 0.75