Published in Biophys J on April 16, 2013
Axon-soma communication in neuronal injury. Nat Rev Neurosci (2013) 1.31
Nucleosome functions in spindle assembly and nuclear envelope formation. Bioessays (2015) 0.79
Mitotic spindle assembly in animal cells: a fine balancing act. Nat Rev Mol Cell Biol (2017) 0.75
How do site-specific DNA-binding proteins find their targets? Nucleic Acids Res (2004) 6.17
Analysis of binding reactions by fluorescence recovery after photobleaching. Biophys J (2004) 5.12
Anomalous diffusion of fluorescent probes inside living cell nuclei investigated by spatially-resolved fluorescence correlation spectroscopy. J Mol Biol (2000) 3.65
Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Nature (2006) 3.47
Spatial coordination of spindle assembly by chromosome-mediated signaling gradients. Science (2005) 3.38
Global chromosome positions are transmitted through mitosis in mammalian cells. Cell (2003) 3.27
Spatial and temporal coordination of mitosis by Ran GTPase. Nat Rev Mol Cell Biol (2008) 2.84
Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin. EMBO J (2009) 2.78
Structure of RCC1 chromatin factor bound to the nucleosome core particle. Nature (2010) 2.61
The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller. Nature (1998) 2.42
N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol (2007) 2.36
Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell (2001) 2.28
Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import. Mol Cell Biol (1999) 2.27
The lac repressor displays facilitated diffusion in living cells. Science (2012) 2.24
The kinetic mechanism of Ran--nucleotide exchange catalyzed by RCC1. Biochemistry (1995) 2.20
Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B. Science (2001) 2.04
Evidence for a common mode of transcription factor interaction with chromatin as revealed by improved quantitative fluorescence recovery after photobleaching. Biophys J (2008) 2.04
Why cytoplasmic signalling proteins should be recruited to cell membranes. Trends Cell Biol (2000) 2.03
Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins. Biophys J (2005) 1.94
Diffusion coefficient measurements in microfluidic devices. Talanta (2002) 1.75
Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells. Genes Dev (2004) 1.73
Direct measurement of association and dissociation rates of DNA binding in live cells by fluorescence correlation spectroscopy. Biophys J (2009) 1.52
Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms. J Cell Biol (2000) 1.50
A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. J Cell Biol (2003) 1.44
Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis. Curr Biol (2004) 1.30
Ran binds to chromatin by two distinct mechanisms. Curr Biol (2002) 1.27
DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication. J Cell Sci (1992) 1.23
The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip. J Biol Chem (2000) 1.21
EGFP-tagged core and linker histones diffuse via distinct mechanisms within living cells. Biophys J (2006) 1.16
Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos. Curr Biol (2002) 1.05
RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex. J Mol Biol (2010) 1.05
Apoptotic histone modification inhibits nuclear transport by regulating RCC1. Nat Cell Biol (2008) 1.02
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science (2005) 5.99
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature (2013) 5.04
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Nat Cell Biol (2007) 4.75
Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum. Science (2002) 3.12
Protein analysis on a proteomic scale. Nature (2003) 3.12
Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling. Nat Cell Biol (2007) 2.91
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell (2010) 2.72
EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation. Nat Cell Biol (2003) 2.49
Small-molecule inhibition of APT1 affects Ras localization and signaling. Nat Chem Biol (2010) 2.37
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat Chem Biol (2011) 2.00
Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron (2009) 1.96
The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins. Nat Cell Biol (2011) 1.87
Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. Curr Opin Cell Biol (2006) 1.64
Spatial organization of intracellular communication: insights from imaging. Nat Rev Mol Cell Biol (2010) 1.55
Imaging activation of two Ras isoforms simultaneously in a single cell. Chembiochem (2005) 1.54
Recruitment of Eph receptors into signaling clusters does not require ephrin contact. J Cell Biol (2004) 1.52
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B. Science (2007) 1.36
In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays. Nat Methods (2010) 1.34
Signaling from the living plasma membrane. Cell (2011) 1.29
Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin. EMBO J (2007) 1.18
Imaging phosphorylation dynamics of the epidermal growth factor receptor. J Biol Chem (2004) 1.16
Cdt1 interactions in the licensing process: a model for dynamic spatiotemporal control of licensing. Cell Cycle (2007) 1.10
Imaging in situ protein-DNA interactions in the cell nucleus using FRET-FLIM. Exp Cell Res (2005) 1.06
Red-edge anisotropy microscopy enables dynamic imaging of homo-FRET between green fluorescent proteins in cells. J Struct Biol (2004) 1.04
Quantitative microscopy and systems biology: seeing the whole picture. Histochem Cell Biol (2008) 1.02
VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells. Am J Physiol Cell Physiol (2009) 1.00
Regulation of Ras localization by acylation enables a mode of intracellular signal propagation. Sci Signal (2010) 0.96
Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues. J Biol Chem (2005) 0.95
Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design. Angew Chem Int Ed Engl (2011) 0.95
Reverse engineering intracellular biochemical networks. Nat Chem Biol (2008) 0.92
Spatial aspects of intracellular information processing. Curr Opin Genet Dev (2010) 0.91
siRNA cell arrays for high-content screening microscopy. Biotechniques (2004) 0.90
Quantitative imaging of apoptosis commitment in colorectal tumor cells. Differentiation (2007) 0.86
Lateral phosphorylation propagation: an aspect of feedback signalling? Nat Rev Mol Cell Biol (2003) 0.84
Fluorescence fluctuations of quantum-dot sensors capture intracellular protein interaction dynamics. Nat Methods (2010) 0.84
A protein-interaction array inside a living cell. Angew Chem Int Ed Engl (2013) 0.82
Imaging protein-protein interactions by Fluorescence Resonance Energy Transfer (FRET) microscopy. Curr Protoc Neurosci (2006) 0.80
Measuring FRET by sensitized emission. CSH Protoc (2006) 0.79
Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery. Chembiochem (2012) 0.79
Imaging protein interactions by FRET microscopy: FRET measurements by acceptor photobleaching. CSH Protoc (2006) 0.79
Configurable low-cost plotter device for fabrication of multi-color sub-cellular scale microarrays. Small (2014) 0.78
High-throughput quantification of posttranslational modifications in situ by CA-FLIM. Methods Enzymol (2011) 0.77
Imaging protein interactions by FRET microscopy: FLIM measurements. CSH Protoc (2006) 0.76
Measuring FRET by acceptor photobleaching. CSH Protoc (2006) 0.75
Optimizing cell arrays for accurate functional genomics. BMC Res Notes (2012) 0.75
FLIM measurements and frequency domain FLIM data analysis. CSH Protoc (2006) 0.75
Imaging protein interactions by FRET microscopy: FRET measurements by sensitized emission. CSH Protoc (2006) 0.75
Imaging protein interactions by FRET microscopy: labeling proteins with fluorescent dyes. CSH Protoc (2006) 0.75
Quantifying cellular dynamics by fluorescence resonance energy transfer (FRET) microscopy. Curr Protoc Neurosci (2013) 0.75
An experimental setup for frequency domain FLIM. CSH Protoc (2006) 0.75
Imaging protein interactions by FRET microscopy: cell preparation for FRET analysis. CSH Protoc (2006) 0.75