Steven L Teitelbaum

Author PubWeight™ 93.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med 2008 3.64
2 IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest 2005 3.56
3 Osteopetrosis. N Engl J Med 2004 2.95
4 Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell 2011 2.84
5 The osteoclast: friend or foe? Annu Rev Pathol 2008 2.45
6 Vav3 regulates osteoclast function and bone mass. Nat Med 2005 2.30
7 Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol 2007 2.27
8 The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis. J Exp Med 2003 2.20
9 c-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation. J Clin Invest 2003 2.19
10 Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc 2014 2.08
11 NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J Biol Chem 2007 1.99
12 Glucocorticoids suppress bone formation via the osteoclast. J Clin Invest 2006 1.92
13 High dose M-CSF partially rescues the Dap12-/- osteoclast phenotype. J Cell Biochem 2003 1.87
14 alphavbeta3 and macrophage colony-stimulating factor: partners in osteoclast biology. Immunol Rev 2005 1.81
15 SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts. Nat Med 2002 1.71
16 Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization. J Clin Invest 2010 1.71
17 Talin1 and Rap1 are critical for osteoclast function. Mol Cell Biol 2012 1.68
18 Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet 2011 1.68
19 Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin. J Cell Biol 2003 1.65
20 M-CSF mediates TNF-induced inflammatory osteolysis. J Clin Invest 2005 1.64
21 Interleukin-4 reversibly inhibits osteoclastogenesis via inhibition of NF-kappa B and mitogen-activated protein kinase signaling. J Biol Chem 2001 1.55
22 DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk. Mol Cell 2008 1.52
23 Marrow stromal cells and osteoclast precursors differentially contribute to TNF-alpha-induced osteoclastogenesis in vivo. J Immunol 2004 1.50
24 The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signaling. J Clin Invest 2004 1.45
25 Animal rights pressure on scientists. Science 2002 1.39
26 Synaptotagmin VII regulates bone remodeling by modulating osteoclast and osteoblast secretion. Dev Cell 2008 1.38
27 FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner. J Clin Invest 2005 1.25
28 Direct inhibition of NF-kappa B blocks bone erosion associated with inflammatory arthritis. J Immunol 2003 1.21
29 Critical role of beta3 integrin in experimental postmenopausal osteoporosis. J Bone Miner Res 2005 1.17
30 c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages. J Biol Chem 2007 1.11
31 Osteoclasts and arthritis. J Bone Miner Res 2009 1.10
32 Rac deletion in osteoclasts causes severe osteopetrosis. J Cell Sci 2011 1.10
33 Noninvasive imaging of osteoclasts in parathyroid hormone-induced osteolysis using a 64Cu-labeled RGD peptide. J Nucl Med 2007 1.10
34 Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state. J Bone Miner Res 2004 1.10
35 SHIP1 negatively regulates proliferation of osteoclast precursors via Akt-dependent alterations in D-type cyclins and p27. J Immunol 2006 1.09
36 Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. Mol Endocrinol 2004 1.09
37 SLP-76 couples Syk to the osteoclast cytoskeleton. J Immunol 2009 1.09
38 Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption. Mol Cell Biol 2005 1.08
39 The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development. J Biol Chem 2006 1.07
40 RANKL employs distinct binding modes to engage RANK and the osteoprotegerin decoy receptor. Structure 2012 1.04
41 M-CSF regulates the cytoskeleton via recruitment of a multimeric signaling complex to c-Fms Tyr-559/697/721. J Biol Chem 2007 1.03
42 Dissection of platelet and myeloid cell defects by conditional targeting of the beta3-integrin subunit. FASEB J 2009 1.00
43 Integrins, growth factors, and the osteoclast cytoskeleton. Ann N Y Acad Sci 2010 0.99
44 Cytoskeletal dysfunction dominates in DAP12-deficient osteoclasts. J Cell Sci 2010 0.99
45 The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. Proc Natl Acad Sci U S A 2009 0.97
46 c-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton. Mol Cell Biol 2012 0.97
47 IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner. J Cell Biochem 2012 0.97
48 Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function. Endocrinology 2002 0.96
49 Tumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclasts. J Biol Chem 2008 0.95
50 Defects in osteoblast function but no changes in long-term repopulating potential of hematopoietic stem cells in a mouse chronic inflammatory arthritis model. Blood 2009 0.94
51 Oophorectomy-induced bone loss is attenuated in MAGP1-deficient mice. J Cell Biochem 2012 0.94
52 Microfibril-associated glycoprotein-1, an extracellular matrix regulator of bone remodeling. J Biol Chem 2010 0.94
53 Genetic variation in the serotonin transporter and HTR1B receptor predicts reduced bone formation during serotonin reuptake inhibitor treatment in older adults. World J Biol Psychiatry 2013 0.87
54 Osteoporosis and integrins. J Clin Endocrinol Metab 2005 0.86
55 An insulin-sensitizing thiazolidinedione, which minimally activates PPARγ, does not cause bone loss. J Bone Miner Res 2015 0.85
56 Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation. J Bone Miner Res 2011 0.85
57 Fyn promotes proliferation, differentiation, survival and function of osteoclast lineage cells. J Cell Biochem 2010 0.83
58 Paxillin contracts the osteoclast cytoskeleton. J Bone Miner Res 2012 0.81
59 Osteoclasts and Arthritis. J Bone Miner Res 2009 0.81
60 Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption. J Cell Biochem 2010 0.81
61 Glucocorticoids and the osteoclast. Ann N Y Acad Sci 2007 0.81
62 Syk tyrosine 317 negatively regulates osteoclast function via the ubiquitin-protein isopeptide ligase activity of Cbl. J Biol Chem 2009 0.81
63 Vinculin regulates osteoclast function. J Biol Chem 2014 0.81
64 Src-like adaptor protein regulates osteoclast generation and survival. J Cell Biochem 2010 0.79
65 Bone weighs in on obesity. Cell 2007 0.78
66 Zap70 inhibits Syk-mediated osteoclast function. J Cell Biochem 2013 0.78
67 Bone: the conundrum of glucocorticoid-induced osteoporosis. Nat Rev Endocrinol 2012 0.76
68 Halofuginone prevents estrogen-deficient osteoporosis in mice. J Cell Biochem 2012 0.76
69 How do bone cells secrete proteins? Adv Exp Med Biol 2010 0.76
70 Comparative proteomic analysis of a cytosolic fraction from β3 integrin-deficient cells. Cancer Genomics Proteomics 2012 0.75
71 Type I phosphotidylinosotol 4-phosphate 5-kinase γ regulates osteoclasts in a bifunctional manner. J Biol Chem 2013 0.75
72 Dexamethsone suppresses bone formation via the osteoclast. Adv Exp Med Biol 2007 0.75
73 Scientific misconduct: ORI survey is flawed. Nature 2002 0.75