Published in Curr Protein Pept Sci on August 01, 2012
Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. J Cell Biol (2013) 0.98
SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis. Mol Biol Cell (2013) 0.93
Characterization of the loss of SUMO pathway function on cancer cells and tumor proliferation. PLoS One (2015) 0.87
SUMO-interacting motifs (SIMs) in Polo-like kinase 1-interacting checkpoint helicase (PICH) ensure proper chromosome segregation during mitosis. Cell Cycle (2016) 0.84
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor. Nat Chem Biol (2017) 0.83
Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. Proteomics (2015) 0.80
Identification of biochemically distinct properties of the small ubiquitin-related modifier (SUMO) conjugation pathway in Plasmodium falciparum. J Biol Chem (2013) 0.79
The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2. PLoS One (2014) 0.79
The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation. Front Physiol (2014) 0.77
Microcompartments and protein machines in prokaryotes. J Mol Microbiol Biotechnol (2013) 0.77
Mapping the SUMOylated landscape. FEBS J (2015) 0.77
Exploring the RING-catalyzed ubiquitin transfer mechanism by MD and QM/MM calculations. PLoS One (2014) 0.76
The GTPase RAN regulates multiple steps of the centrosome life cycle. Chromosome Res (2016) 0.76
Depletion of UBC9 Causes Nuclear Defects during the Vegetative and Sexual Life Cycles in Tetrahymena thermophila. Eukaryot Cell (2015) 0.75
SUMO and the robustness of cancer. Nat Rev Cancer (2017) 0.75
The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol (2007) 18.33
Concepts in sumoylation: a decade on. Nat Rev Mol Cell Biol (2007) 11.48
Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol (2006) 10.74
Protein modification by SUMO. Annu Rev Biochem (2004) 10.59
PCNA, the maestro of the replication fork. Cell (2007) 10.43
SUMO: a history of modification. Mol Cell (2005) 10.40
Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell (2003) 9.90
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell (1997) 9.01
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell (2006) 8.44
Molecular architecture of the kinetochore-microtubule interface. Nat Rev Mol Cell Biol (2008) 8.21
CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell (1997) 8.08
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol (1996) 7.64
Polyubiquitin chains: polymeric protein signals. Curr Opin Chem Biol (2004) 7.10
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol (2007) 6.83
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol Cell (1998) 6.62
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell (2006) 6.46
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol (2009) 6.43
The cellular geography of aurora kinases. Nat Rev Mol Cell Biol (2003) 6.40
Transport into and out of the nucleus. Microbiol Mol Biol Rev (2001) 6.36
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat Cell Biol (2008) 5.90
The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell (2002) 5.80
A new protease required for cell-cycle progression in yeast. Nature (1999) 5.44
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting. J Biol Chem (2000) 4.96
The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. Nat Cell Biol (2006) 4.89
An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell (2001) 4.81
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J (1997) 4.80
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev (2004) 4.80
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
Chromosomes can congress to the metaphase plate before biorientation. Science (2006) 4.64
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature (2005) 4.63
Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell (1995) 4.23
CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J (1991) 4.22
Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature (1995) 4.20
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell (2002) 4.09
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat Cell Biol (2000) 3.96
The polycomb protein Pc2 is a SUMO E3. Cell (2003) 3.91
Modification in reverse: the SUMO proteases. Trends Biochem Sci (2007) 3.84
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p. J Biol Chem (1997) 3.76
SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex. J Cell Biol (1998) 3.65
The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification. J Biol Chem (2001) 3.64
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A (2005) 3.62
CENP-E function at kinetochores is essential for chromosome alignment. J Cell Biol (1997) 3.49
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Cell (2010) 3.26
The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol Cell Biol (2000) 3.24
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev Cell (2002) 3.23
SUMOylation and De-SUMOylation: wrestling with life's processes. J Biol Chem (2008) 3.22
Mechanisms of chromosomal instability. Curr Biol (2010) 3.21
Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J Cell Biol (1998) 3.11
Chromosome alignment and segregation regulated by ubiquitination of survivin. Science (2005) 3.09
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. J Cell Sci (2004) 3.01
SUMO: ligases, isopeptidases and nuclear pores. Trends Biochem Sci (2003) 2.92
The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo. Curr Biol (2004) 2.88
Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex. Mol Cell Biol (2002) 2.85
The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell (2002) 2.85
The RanGTP gradient - a GPS for the mitotic spindle. J Cell Sci (2008) 2.78
Ubch9 conjugates SUMO but not ubiquitin. FEBS Lett (1997) 2.73
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J Cell Biol (2002) 2.60
SUMO junction-what's your function? New insights through SUMO-interacting motifs. EMBO Rep (2007) 2.58
Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat Cell Biol (2005) 2.56
Regulation of cell cycle progression and gene expression by H2A deubiquitination. Nature (2007) 2.52
SUMO-specific proteases: a twist in the tail. Trends Cell Biol (2007) 2.50
RanBP2 associates with Ubc9p and a modified form of RanGAP1. Proc Natl Acad Sci U S A (1997) 2.42
The SUMO isopeptidase Ulp2 prevents accumulation of SUMO chains in yeast. J Biol Chem (2003) 2.38
Differential regulation of sentrinized proteins by a novel sentrin-specific protease. J Biol Chem (2000) 2.34
Association of the human SUMO-1 protease SENP2 with the nuclear pore. J Biol Chem (2002) 2.33
Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol Cell Biol (2005) 2.31
Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association. J Cell Biol (1998) 2.29
Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. Mol Cell Biol (2005) 2.28
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell (2008) 2.25
SUMO-2/3 regulates topoisomerase II in mitosis. J Cell Biol (2003) 2.24
SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell (2001) 2.23
Nup358 integrates nuclear envelope breakdown with kinetochore assembly. J Cell Biol (2003) 2.21
KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates. Mol Biol Cell (2007) 2.20
Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors. Mol Cell Biol (2005) 2.18
SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes Dev (2006) 2.16
Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. J Biol Chem (2006) 2.15
SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis. Mol Cell (2008) 2.15
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. Structure (2004) 2.15
Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif. Mol Cell (2010) 2.10
Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex. Curr Biol (2005) 2.10
Rod-Zw10-Zwilch: a key player in the spindle checkpoint. Trends Cell Biol (2005) 2.06
Sumoylation regulates diverse biological processes. Cell Mol Life Sci (2007) 2.03
The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol (2003) 1.97
CENP-I is essential for centromere function in vertebrate cells. Dev Cell (2002) 1.94
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. EMBO J (2007) 1.92
Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates. J Biol Chem (2001) 1.89
Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics (2001) 1.89
Clearing the way for mitosis: is cohesin a target? Nat Rev Mol Cell Biol (2009) 1.88
Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1. J Biol Chem (2003) 1.88
Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2. Curr Biol (1998) 1.86
The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis. J Cell Sci (1995) 1.85
The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle. Mol Cell Proteomics (2008) 1.81
The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol (2006) 1.81
Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest. Trends Cell Biol (2005) 1.80
Centromeres: unique chromatin structures that drive chromosome segregation. Nat Rev Mol Cell Biol (2011) 1.80
CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. J Cell Biol (2008) 1.77
Comparison of SUMO fusion technology with traditional gene fusion systems: enhanced expression and solubility with SUMO. Protein Sci (2005) 1.73
The ABCs of CENPs. Chromosoma (2011) 1.72
Purification and identification of endogenous polySUMO conjugates. EMBO Rep (2011) 1.72
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J Cell Biol (2006) 1.67
Arsenic and fluoride exposure in drinking water: children's IQ and growth in Shanyin county, Shanxi province, China. Environ Health Perspect (2007) 2.03
Automated identification of SUMOylation sites using mass spectrometry and SUMmOn pattern recognition software. Nat Methods (2006) 1.68
PARP-1 transcriptional activity is regulated by sumoylation upon heat shock. EMBO J (2009) 1.33
Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1. Mol Cell (2009) 1.22
SUMO: the glue that binds. Dev Cell (2006) 1.20
Developmental control of sumoylation pathway proteins in mouse male germ cells. Dev Biol (2008) 1.09
An improved SUMmOn-based methodology for the identification of ubiquitin and ubiquitin-like protein conjugation sites identifies novel ubiquitin-like protein chain linkages. Proteomics (2010) 0.85
Analysis of changes in SUMO-2/3 modification during breast cancer progression and metastasis. J Proteome Res (2014) 0.82
Self-assembly multifunctional nanocomposites with Fe3O4 magnetic core and CdSe/ZnS quantum dots shell. J Biomed Mater Res A (2008) 0.81
Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. Proteomics (2015) 0.80
Ub in charge: regulating E2 enzyme nuclear import. Nat Cell Biol (2005) 0.80
Direct asymmetric hydrogenation of α-keto acids by using the highly efficient chiral spiro iridium catalysts. Chem Commun (Camb) (2014) 0.76
Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent. J Mater Sci Mater Med (2010) 0.76
Chromosome movement via multiple motors: novel relationships between KIF18A and CENP-E revealed. Cell Cycle (2009) 0.75
[Sonocatalytic degradation of ethyl violet in the presence of high dispersion TiO2 and the comparison of catalytic activity with suspension TiO2]. Huan Jing Ke Xue (2007) 0.75
[Influences of intervention on the abilities of detecting pulmonary tuberculosis cases in general hospitals]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2009) 0.75
Bis[4-(2-hydroxy-benzyl-amino)phen-yl] ether. Acta Crystallogr Sect E Struct Rep Online (2008) 0.75
Sonocatalytic degradation of methyl orange in the presence of (nanometer and ordinary) anatase TiO2 powders. J Environ Sci (China) (2005) 0.75