Published in J Immunol on July 30, 2012
The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection. Nat Immunol (2014) 1.77
CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype. Nat Immunol (2014) 1.43
Global DNA methylation remodeling accompanies CD8 T cell effector function. J Immunol (2013) 1.27
Adjuvant-specific regulation of long-term antibody responses by ZBTB20. J Exp Med (2014) 1.25
The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity. J Exp Med (2014) 1.21
Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection. J Exp Med (2014) 0.99
A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma. PLoS One (2013) 0.99
Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation. Nat Immunol (2016) 0.88
NF-κB regulates PD-1 expression in macrophages. J Immunol (2015) 0.83
DCIR2+ cDC2 DCs and Zbtb32 Restore CD4+ T-Cell Tolerance and Inhibit Diabetes. Diabetes (2015) 0.82
Tzfp represses the androgen receptor in mouse testis. PLoS One (2013) 0.81
Subtype-specific addiction of the activated B-cell subset of diffuse large B-cell lymphoma to FOXP1. Proc Natl Acad Sci U S A (2016) 0.81
Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment. Nucleic Acids Res (2015) 0.79
Oct1 and OCA-B are selectively required for CD4 memory T cell function. J Exp Med (2015) 0.78
Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types. Genes Immun (2014) 0.78
ZBTB32 Restricts the Duration of Memory B Cell Recall Responses. J Immunol (2016) 0.78
B cell differentiation is associated with reprogramming the CCCTC binding factor-dependent chromatin architecture of the murine MHC class II locus. J Immunol (2014) 0.77
Identification of co-expressed gene signatures in mouse B1, marginal zone and B2 B-cell populations. Immunology (2014) 0.77
RelA and RelB cross-talk and function in Epstein-Barr virus transformed B cells. Leukemia (2013) 0.76
Transcriptome Profiling Reveals Disruption of Innate Immunity in Chronic Heavy Ethanol Consuming Female Rhesus Macaques. PLoS One (2016) 0.75
Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory. PLoS Pathog (2017) 0.75
Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88
Plasma cell differentiation requires the transcription factor XBP-1. Nature (2001) 9.72
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity (2002) 6.27
Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity (2003) 5.95
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell (1993) 4.80
Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell (1994) 4.60
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity (2009) 4.42
Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA. Science (1994) 3.71
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol (2006) 3.65
Transcriptional repressor Blimp-1 regulates T cell homeostasis and function. Nat Immunol (2006) 3.48
PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing. Nat Immunol (2004) 3.39
Bone marrow is a major site of long-term antibody production after acute viral infection. J Virol (1995) 3.32
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell (2004) 3.12
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nat Immunol (2006) 3.09
Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science (1997) 2.93
Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 2.83
Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med (2004) 2.76
Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J Immunol (2000) 2.67
Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. Immunity (2007) 2.61
Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. Mol Cell Biol (2000) 2.24
Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol Cell Biol (2002) 2.24
PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins. Genes Dev (1999) 2.09
CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter. Nat Immunol (2001) 1.89
BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nat Immunol (2000) 1.76
Murine model for evaluation of protective immunity to influenza virus. Vaccine (1993) 1.73
Epigenetic regulation of MHC-II and CIITA genes. Trends Immunol (2006) 1.73
Transcriptional regulation of the MHC class II antigen presentation pathway. Curr Opin Immunol (2003) 1.48
ROG, repressor of GATA, regulates the expression of cytokine genes. Immunity (2000) 1.46
Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA. J Exp Med (1994) 1.46
Gene expression profiling reveals a highly specialized genetic program of plasma cells. Blood (2003) 1.34
Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene. J Exp Med (2001) 1.32
CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA. Immunity (2003) 1.30
Involvement of histone demethylase LSD1 in Blimp-1-mediated gene repression during plasma cell differentiation. Mol Cell Biol (2009) 1.29
A role for Blimp1 in the transcriptional network controlling natural killer cell maturation. Blood (2010) 1.26
New insights into the regulation of human B-cell differentiation. Trends Immunol (2009) 1.26
Terminal differentiation of lymphocytes depends on Blimp-1. Curr Opin Immunol (2007) 1.24
The role of BTB domain-containing zinc finger proteins in T cell development and function. Immunol Lett (2006) 1.23
Regulation of major histocompatibility complex class II genes. Curr Opin Immunol (2010) 1.15
Regulatory events in early and late B-cell differentiation. Mol Immunol (2005) 1.07
Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis. Mol Cell Biol (2004) 1.07
E47, IRF-4, and PU.1 synergize to induce B-cell-specific activation of the class II transactivator promoter III (CIITA-PIII). Blood (2004) 1.05
Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation. J Biol Chem (2011) 1.04
The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol (2011) 1.04
Differentiation of the secondary B-lymphocyte repertoire: the germinal center reaction. Immunol Rev (1994) 1.02
A role for EZH2 in silencing of IFN-gamma inducible MHC2TA transcription in uveal melanoma. J Immunol (2007) 1.01
Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex. J Immunol (1997) 1.01
The zinc finger domain of Tzfp binds to the tbs motif located at the upstream flanking region of the Aie1 (aurora-C) kinase gene. J Biol Chem (2001) 0.97
Transcriptional control of MHC class II gene expression during differentiation from B cells to plasma cells. J Immunol (1989) 0.96
Positive regulatory domain I-binding factor 1 mediates repression of the MHC class II transactivator (CIITA) type IV promoter. Mol Immunol (2006) 0.93
Active suppression of major histocompatibility complex class II gene expression during differentiation from B cells to plasma cells. Proc Natl Acad Sci U S A (1988) 0.92
Early epigenetic events regulate the adaptive immune response gene CIITA. Epigenetics (2011) 0.92
Protease treatment of nuclear extracts distinguishes between class II MHC X1 box DNA-binding proteins in wild-type and class II-deficient B cells. J Immunol (1993) 0.91
ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation. Mol Cell Biol (2005) 0.89
A repressor of GATA-mediated negative feedback mechanism of T cell activation. J Immunol (2004) 0.86
Multiple histone methyl and acetyltransferase complex components bind the HLA-DRA gene. PLoS One (2012) 0.86
The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific. J Biol Chem (2002) 0.86
Extended presentation of specific MHC-peptide complexes by mature dendritic cells compared to other types of antigen-presenting cells. Eur J Immunol (2004) 0.86
Multiple roles for Blimp-1 in B and T lymphocytes. Adv Exp Med Biol (2007) 0.84
The generation and selection of the T cell repertoire: insights from studies of the molecular basis of T cell recognition. Immunol Rev (1988) 0.84
Epigenetic regulation during B cell differentiation controls CIITA promoter accessibility. J Immunol (2006) 0.83
The molecular basis of MHC-restricted antigen recognition by T cells. Int Rev Immunol (1988) 0.78
Restoring function in exhausted CD8 T cells during chronic viral infection. Nature (2005) 28.04
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature (2006) 20.00
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol (2003) 15.51
Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol (2003) 15.51
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol (2003) 11.48
Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity (2007) 10.83
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature (2008) 10.80
mTOR regulates memory CD8 T-cell differentiation. Nature (2009) 10.07
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol (2005) 8.27
Molecular and functional profiling of memory CD8 T cell differentiation. Cell (2002) 8.06
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol (2007) 7.60
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. J Exp Med (2011) 7.29
Memory CD8 T-cell differentiation during viral infection. J Virol (2004) 6.75
Redefining chronic viral infection. Cell (2009) 6.30
Systems biology of vaccination for seasonal influenza in humans. Nat Immunol (2011) 6.09
Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell (2004) 6.08
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. J Virol (2006) 6.00
Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature (2008) 5.94
Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol (2003) 5.90
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J Exp Med (2008) 5.71
Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med (2002) 5.64
Cutting edge: long-term B cell memory in humans after smallpox vaccination. J Immunol (2003) 5.51
Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity (2008) 5.22
Programming the magnitude and persistence of antibody responses with innate immunity. Nature (2011) 5.18
Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med (2002) 5.16
The NLR gene family: a standard nomenclature. Immunity (2008) 4.77
Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. J Immunol Methods (2004) 4.57
Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proc Natl Acad Sci U S A (2004) 4.56
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2010) 4.56
Cutting edge: rapid in vivo killing by memory CD8 T cells. J Immunol (2003) 4.25
Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J Exp Med (2006) 4.23
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J Exp Med (2006) 4.17
Heterologous immunity provides a potent barrier to transplantation tolerance. J Clin Invest (2003) 4.14
Dynamic T cell migration program provides resident memory within intestinal epithelium. J Exp Med (2010) 4.09
Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity (2010) 4.06
Translating innate immunity into immunological memory: implications for vaccine development. Cell (2006) 3.98
SAP is required for generating long-term humoral immunity. Nature (2003) 3.85
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. J Virol (2008) 3.83
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nat Med (2003) 3.68
Immunological mechanisms of vaccination. Nat Immunol (2011) 3.35
Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J Immunol (2006) 3.35
From vaccines to memory and back. Immunity (2010) 3.30
Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nat Protoc (2009) 3.30
Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J Immunol (2006) 3.29
Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proc Natl Acad Sci U S A (2012) 3.27
A Blueprint for HIV Vaccine Discovery. Cell Host Microbe (2012) 3.27
Dissolving polymer microneedle patches for influenza vaccination. Nat Med (2010) 3.24
Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity (2011) 3.19
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell (2004) 3.12
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. J Exp Med (2008) 2.81
Original antigenic sin responses to influenza viruses. J Immunol (2009) 2.76
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. Nat Immunol (2011) 2.76
The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. J Immunol (2009) 2.68
Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science (2007) 2.67
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science (2009) 2.64
Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J Virol (2002) 2.64
Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. J Exp Med (2006) 2.55
The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. J Exp Med (2008) 2.50
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity (2011) 2.49
Memory CD8 T-cell compartment grows in size with immunological experience. Nature (2008) 2.49
The role of models in understanding CD8+ T-cell memory. Nat Rev Immunol (2005) 2.43
High antigen levels are the cause of T cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2009) 2.42
Features of responding T cells in cancer and chronic infection. Curr Opin Immunol (2010) 2.42
The role of programming in memory T-cell development. Curr Opin Immunol (2004) 2.41
Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells. Cancer Res (2006) 2.40
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci U S A (2007) 2.39
Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J Infect Dis (2004) 2.29
Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo. J Immunol (2002) 2.26
Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination. J Virol (2007) 2.21
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity (2012) 2.16
Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes. J Infect Dis (2008) 2.14
Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics (2007) 2.10
Generation and maintenance of immunological memory. Semin Immunol (2004) 2.06
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. J Virol (2005) 2.06
Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection. Immunity (2013) 2.05
Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation. J Immunol (2007) 2.04
Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells. J Immunol (2005) 1.95
Immunological memory in humans. Semin Immunol (2004) 1.90
Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J Immunol (2003) 1.83
Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge. Proc Natl Acad Sci U S A (2009) 1.82
NFATc1 regulates PD-1 expression upon T cell activation. J Immunol (2008) 1.81
Transdermal influenza immunization with vaccine-coated microneedle arrays. PLoS One (2009) 1.78
Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought. J Virol (2006) 1.78
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. J Virol (2009) 1.77
Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus. J Immunol (2010) 1.74
Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. J Virol (2012) 1.74
Accelerating next-generation vaccine development for global disease prevention. Science (2013) 1.73
Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D. J Immunol (2007) 1.71
Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation. Virology (2003) 1.69
Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults. J Immunol (2011) 1.66
Defective generation but normal maintenance of memory T cells in old mice. Eur J Immunol (2002) 1.64
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. J Immunol (2008) 1.63
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proc Natl Acad Sci U S A (2011) 1.62
BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proc Natl Acad Sci U S A (2005) 1.61
Requirement of B cells for generating CD4+ T cell memory. J Immunol (2009) 1.60
Differentiation of memory B and T cells. Curr Opin Immunol (2006) 1.59