Published in Acta Crystallogr Sect F Struct Biol Cryst Commun on July 27, 2012
Errors in Crystal structure of HINT from Helicobacter pylori. Acta Crystallogr F Struct Biol Commun (2016) 1.07
Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease. Prog Biophys Mol Biol (2015) 0.81
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human histidine triad nucleotide-binding protein 2 (hHINT2). Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.80
Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. ACS Med Chem Lett (2016) 0.75
Solvent content of protein crystals. J Mol Biol (1968) 106.07
Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers (1983) 99.69
Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46
Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55
Inference of macromolecular assemblies from crystalline state. J Mol Biol (2007) 44.95
REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr D Biol Crystallogr (2011) 39.32
Molecular replacement with MOLREP. Acta Crystallogr D Biol Crystallogr (2009) 26.26
iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM. Acta Crystallogr D Biol Crystallogr (2011) 18.13
Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases. Biochemistry (2002) 2.42
Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science (1997) 2.27
Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nat Struct Biol (1997) 1.96
Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. J Biol Chem (2010) 1.60
Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3. J Biol Chem (2002) 1.58
Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis. Proc Natl Acad Sci U S A (2003) 1.55
Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins. Proc Natl Acad Sci U S A (1996) 1.41
The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells. Immunity (2004) 1.36
The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activity. J Biol Chem (2006) 1.32
Amino acid sequence and characterization of a protein inhibitor of protein kinase C. J Biol Chem (1990) 1.32
The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF-beta-catenin-mediated transcription. J Cell Sci (2005) 1.31
Hint1 is a haplo-insufficient tumor suppressor in mice. Oncogene (2006) 1.27
The protein content in crystals and packing coefficients in different space groups. Acta Crystallogr D Biol Crystallogr (2000) 1.24
Role of mPKCI, a novel mu-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia. Mol Pharmacol (2004) 1.13
31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions. J Biol Chem (2005) 1.12
Meta-analysis of 12 genomic studies in bipolar disorder. J Mol Neurosci (2007) 1.12
Lysyl-tRNA synthetase-generated lysyl-adenylate is a substrate for histidine triad nucleotide binding proteins. J Biol Chem (2006) 1.09
Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia. Neurochem Res (2004) 1.07
Engineered monomeric human histidine triad nucleotide-binding protein 1 hydrolyzes fluorogenic acyl-adenylate and lysyl-tRNA synthetase-generated lysyl-adenylate. J Biol Chem (2007) 1.06
Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp Cell Res (1998) 1.04
Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells. Cancer Res (2007) 1.00
Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors. J Biol Chem (2004) 0.99
Nonconventional involvement of LysRS in the molecular mechanism of USF2 transcriptional activity in FcepsilonRI-activated mast cells. Mol Cell Biol (2005) 0.97
Silencing of Hint1, a novel tumor suppressor gene, by promoter hypermethylation in hepatocellular carcinoma. Cancer Lett (2008) 0.95
Supersensitivity to amphetamine in protein kinase-C interacting protein/HINT1 knockout mice. Neuropsychopharmacology (2007) 0.95
Altered specificity of Hint-W123Q supports a role for Hint inhibition by ASW in avian sex determination. Physiol Genomics (2004) 0.95
HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells. Int J Cancer (2009) 0.94
Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia? Schizophr Res (2008) 0.93
The histidine triad protein Hint is not required for murine development or Cdk7 function. Mol Cell Biol (2003) 0.93
Isolation, cloning and characterization of a low-molecular-mass purine nucleoside- and nucleotide-binding protein. Biochem J (1997) 0.92
Increased anxiety-related behaviour in Hint1 knockout mice. Behav Brain Res (2011) 0.91
Probing the impact of the echinT C-terminal domain on structure and catalysis. J Mol Biol (2010) 0.89
Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src. J Biol Chem (2008) 0.89
Identifying apoptosis-evasion proteins/pathways in human hepatoma cells via induction of cellular hormesis by UV irradiation. J Proteome Res (2009) 0.89
Characterization of a monomeric Escherichia coli alkaline phosphatase formed upon a single amino acid substitution. J Biol Chem (2003) 0.89
Distribution and expression of protein kinase C interactive protein (PKCI/HINT1) in mouse central nervous system (CNS). Neurochem Res (2008) 0.88
Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level. BMC Neurosci (2009) 0.88
Side chain independent recognition of aminoacyl adenylates by the Hint1 transcription suppressor. J Phys Chem B (2012) 0.87
High-resolution X-ray structure of the rabbit histidine triad nucleotide-binding protein 1 (rHINT1)-adenosine complex at 1.10 Å resolution. Acta Crystallogr D Biol Crystallogr (2011) 0.86
Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP). Int J Cancer (2010) 0.85
Plant nucleoside 5'-phosphoramidate hydrolase; simple purification from yellow lupin (Lupinus luteus) seeds and properties of homogeneous enzyme. Acta Biochim Pol (2011) 0.81
[HINT1--a novel tumor suppressor protein of the HIT superfamily]. Postepy Biochem (2010) 0.80
Stereochemistry of rHint1 hydrolase assisted cleavage of P-N bond in nucleoside 5'-O-phosphoramidothioates. Chem Commun (Camb) (2007) 0.79
First identification and functional analysis of a histidine triad nucleotide binding protein in an invertebrate species Haliotis diversicolor supertexta. Dev Comp Immunol (2009) 0.78
Effect of base modifications on structure, thermodynamic stability, and gene silencing activity of short interfering RNA. RNA (2007) 1.16
Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding. Proc Natl Acad Sci U S A (2003) 1.14
Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1. J Biol Chem (2003) 0.99
S100A6 binds p53 and affects its activity. Int J Biochem Cell Biol (2008) 0.97
Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5'-O-phosphorothioates to nucleoside 5'-O-phosphates. J Biol Chem (2010) 0.95
Catalytic phosphoryl interactions of topoisomerase IB. Biochemistry (2005) 0.94
High-resolution X-ray structure of the rabbit histidine triad nucleotide-binding protein 1 (rHINT1)-adenosine complex at 1.10 Å resolution. Acta Crystallogr D Biol Crystallogr (2011) 0.86
Gene silencing activity of siRNA molecules containing phosphorodithioate substitutions. ACS Chem Biol (2012) 0.85
Gastric ghrelin in relation to gender, stomach topography and Helicobacter pylori in dyspeptic patients. World J Gastroenterol (2009) 0.84
Family history of gastric cancer correlates with decreased expression of HINT1 tumor suppressor gene in gastric mucosa of dyspeptic patients. Oncol Lett (2011) 0.83
Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection. World J Gastroenterol (2005) 0.83
Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients. Helicobacter (2009) 0.82
The 2-thiouridine unit in the RNA strand is desulfured predominantly to 4-pyrimidinone nucleoside under in vitro oxidative stress conditions. Chem Commun (Camb) (2011) 0.82
Rhodium(III) and iridium(III) complexes with 1,2-naphthoquinone-1-oximate as a bidentate ligand: synthesis, structure, and biological activity. J Biol Inorg Chem (2009) 0.82
Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference. Int J Alzheimers Dis (2011) 0.81
A single nuclease-resistant linkage in DNA as a versatile tool for the characterization of DNA lesions: application to the guanine oxidative lesion "G+34" generated by metalloporphyrin/KHSO(5) reagent. Chem Res Toxicol (2012) 0.81
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human histidine triad nucleotide-binding protein 2 (hHINT2). Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.80
RNA interference in silencing of genes of Alzheimer's disease in cellular and rat brain models. Nucleic Acids Symp Ser (Oxf) (2008) 0.79
Water-soluble polycationic dendrimers with a phosphoramidothioate backbone: preliminary studies of cytotoxicity and oligonucleotide/plasmid delivery in human cell culture. Oligonucleotides (2003) 0.79
Evaluation of BACE1 Silencing in Cellular Models. Int J Alzheimers Dis (2009) 0.79
Biological evaluation of novel Pt(II) and Pd(II) complexes with pyrazole-containing ligands. Eur J Pharmacol (2004) 0.78
5-Ethynyl-1-β-D-ribofuranosyl-1H-[1,2,3]triazole-4-carboxylic acid amide (ETCAR) and its analogues: synthesis and cytotoxic properties. Bioorg Med Chem (2011) 0.78
[Effect of Helicobacter pylori eradication on the expression level of SATB1 and c-Myc genes in gastric mucosa of patients with family history of gastric cancer]. Pol Merkur Lekarski (2013) 0.78
Desulfuration of 2-thiouridine with hydrogen peroxide in the physiological pH range 6.6-7.6 is pH-dependent and results in two distinct products. Bioorg Med Chem Lett (2013) 0.78
siRNAs modified with boron cluster and their physicochemical and biological characterization. Bioconjug Chem (2013) 0.77
LNA units present in the (2'-OMe)-RNA strand stabilize parallel duplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA and parallel triplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription. Org Biomol Chem (2015) 0.77
Synthesis of a fluorescent cationic phosphorus dendrimer and preliminary biological studies of its interaction with DNA. Nucleosides Nucleotides Nucleic Acids (2010) 0.77
Wheat (Triticum vulgare) chloroplast nuclease ChSI exhibits 5' flap structure-specific endonuclease activity. Biochemistry (2004) 0.76
Evaluation of influence of Ap4A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis. Bioorg Med Chem (2011) 0.76
Expression of somatostatin receptor subtype 3 in the gastric mucosa of dyspeptic patients in relation to Helicobacter pylori infection and a family history of gastric cancer. J Gastroenterol Hepatol (2007) 0.76
Guanosine in a single stranded region of anticodon stem-loop tRNA models is prone to oxidatively generated damage resulting in dehydroguanidinohydantoin and spiroiminodihydantoin lesions. Chemistry (2015) 0.76
Longer 19-base pair short interfering RNA duplexes rather than shorter duplexes trigger RNA interference. Oligonucleotides (2010) 0.76
[FHIT--tumor suppressor protein involved in induction of apoptosis and cell cycle regulation]. Postepy Biochem (2009) 0.76
The differences in the relationship between diastolic dysfunction, selected biomarkers and collagen turn-over in heart failure patients with preserved and reduced ejection fraction. Cardiol J (2016) 0.75
Discrimination in metal-ion binding to RNA dinucleotides with a non-bridging oxygen or sulfur in the phosphate diester link. Chemistry (2008) 0.75
Contamination of the surgical field in head and neck oncologic surgery. Head Neck (2013) 0.75
An oxathiaphospholane approach to one-pot phosphorothioylation of isoprenoid alcohols. Org Lett (2004) 0.75
[The clinical significance of GastroPanel in diagnostics of Helicobacter pylori eradication efficiency in patients with dyspepsia with correlation of family history of gastric cancer]. Pol Merkur Lekarski (2013) 0.75
New, Substituted Derivatives of Dicarboximides and their Cytotoxic Properties. Anticancer Agents Med Chem (2016) 0.75
Reaction of S-geranyl-2-thiouracil modified oligonucleotides with alkyl amines leads to the N2-alkyl isocytosine derivatives. Org Biomol Chem (2017) 0.75
[Somatostatin receptor subtype 3 (SSTR3) mRNA level in gastric mucosa of patients with dyspepsia]. Pol Merkur Lekarski (2007) 0.75
Versatile method for the site specific modification of DNA with boron clusters - Anti-EGFR antisense oligonucleotide case. Chemistry (2017) 0.75